• Journal of Platform Technology
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• v.6 no.4
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• pp.26-33
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• 2018

In this paper, we propose an image retrieval algorithm for real-time processing and design it as hardware. The proposed method is based on the classification of BoWs(Bag of Words) algorithm and proposes an image search algorithm using bit stream. K-fold cross validation is used for the verification of the algorithm. Data is classified into seven classes, each class has seven images and a total of 49 images are tested. The test has two kinds of accuracy measurement and speed measurement. The accuracy of the image classification was 86.2% for the BoWs algorithm and 83.7% the proposed hardware-accelerated software implementation algorithm, and the BoWs algorithm was 2.5% higher. The image retrieval processing speed of BoWs is 7.89s and our algorithm is 1.55s. Our algorithm is 5.09 times faster than BoWs algorithm. The algorithm is largely divided into software and hardware parts. In the software structure, C-language is used. The Scale Invariant Feature Transform algorithm is used to extract feature points that are invariant to size and rotation from the image. Bit streams are generated from the extracted feature point. In the hardware architecture, the proposed image retrieval algorithm is written in Verilog HDL and designed and verified by FPGA and Design Compiler. The generated bit streams are stored, the clustering step is performed, and a searcher image databases or an input image databases are generated and matched. Using the proposed algorithm, we can improve convenience and satisfaction of the user in terms of speed if we search using database matching method which represents each object.

• Microbiology and Biotechnology Letters
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• v.47 no.1
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• pp.139-147
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• 2019

Glutamate decarboxylase catalyzes the conversion of glutamate to gamma-aminobutyric acid (GABA), contributing to pH homeostasis through proton consumption. The reaction is the first step toward the GABA shunt. To date, the enzymes involved in the glutamate metabolism of Photobacterium damselae subsp. piscicida have not been elucidated. In this study, an open reading frame of P. damselae subsp. piscicida, showing homology to the glutamate decarboxylase or putative pyridoxal-dependent aspartate 1-decarboxylase genes, was isolated and cloned into an expression vector to produce the recombinant enzyme. Preliminary gas chromatography-mass spectrometry characterization of the purified recombinant enzyme revealed that it catalyzed not only the decarboxylation of glutamate but also the transamination of GABA. This enzyme of P. damselae subsp. piscicida could be bifunctional, combining decarboxylase and transaminase activities in a single polypeptide chain.

• Journal of KIBIM
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• v.11 no.2
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• pp.1-16
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• 2021

Since entering the 21st century, the construction industry has developed faster and faster, and more and more technologies have been applied in the construction industry. BIM technology (Building Information Modeling) was born in this environment. The application of BIM technology can greatly improve the efficiency of cost management and help achieve the goal of cost management. But through BIM to realize project cost management, there is still no good solution. In order to solve this problem, this paper puts forward the concept of WBS structure applied to construction projects by studying the BoQ (Bill of Quantities) list based on BIM, and proposes the numbering method of the structure. The WBS (Work Breakdown Structure) structure proposed in this paper divides more than 5000 cost objects into 133 projects according to the type of work and project schedule. This structure helps to realize the application of BIM in project cost management. Although this article has studied more than 5000 data of three projects, it does not think that it can cover all cost objects in the existing construction industry. The purpose of this article is to propose a solution for cost and Process Control using BIM-based BoQ data.

• Journal of Korean Academy of Dental Administration
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• v.9 no.1
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• pp.1-6
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• 2021

Measuring and quantifying the burden of disease (BoD) is crucial for healthcare policy-related decisions. For this purpose, summary measures of population health (SMPH) have been proposed to overcome the limitations of prevalence, incidence, and mortality. Oral health remains separated from the mainstream healthcare system, and the lack of reliable epidemiological data has been pointed out as the cause. In this study, we aimed to understand the flow of international and domestic BoD research related to oral disorders and the direction in which those studies should advance in the future. It is necessary to continuously revise the previously measured BoD of oral disorders and calculate the BoD by performing subdivisions, starting from the development of lay descriptions. Furthermore, developing elaborate BoD measurement methodologies that reflect the complexity of the oral cavity is essential.

• Journal of Veterinary Science
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• v.21 no.5
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• pp.72.1-72.10
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• 2020

Background: Fenbendazole, a dewormer drug, is used widely in the clinical treatment of parasite infections in animals. Recent studies have shown that fenbendazole has substantial effects on tumor growth, immune responses, and inflammatory responses, suggesting that fenbendazole is a pluripotent drug. Nevertheless, the antiviral effects have not been reported. Fenbendazole can disrupt microtubules, which are essential for multiple viruses infections, suggesting that fenbendazole might have antiviral effects. Objectives: This study examined whether fenbendazole could inhibit bovine herpesvirus 1 (BoHV-1) productive infection in cell cultures. Methods: The effects of fenbendazole on viral production, transcription of the immediate early (IE) genes, viron-associated protein expression, and the cellular signaling PLC-γ1/Akt pathway were assessed using distinct methods. Results: Fenbendazole could inhibit BoHV-1 productive infections significantly in MDBK cells in a dose-dependent manner. A time-of-addition assay indicated that fenbendazole affected both the early and late stages in the virus replication cycles. The transcription of IE genes, including BoHV-1 infected cell protein 0 (bICP0), bICP4, and bICP22, as well as the synthesis of viron-associated proteins, were disrupted differentially by the fenbendazole treatment. The treatment did not affect the cellular signaling pathway of PLC-γ1/Akt, a known cascade playing important roles in virus infection. Conclusions: Overall, fenbendazole has antiviral effects on BoHV-1 replication.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.347-347
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• 2022

최근 데이터 사이언스의 비약적인 발전과 함께 다양한 형태의 딥러닝 알고리즘이 개발되어 수자원 분야에도 적용되고 있다. 이 연구에서는 LSTM(Long Short-Term Memory) 네트워크와 BO-LSTM이라는 베이지안 최적화(BO) 기술을 결합하여 일단위 앙상블 미래 댐유입량을 projection하는 딥 러닝 모델을 제안하였다. BO-LSTM 하이퍼파라미터 및 손실 함수는 베이지안 최적화 기법을 통해 훈련 및 최적화되며, BO 접근법은 모델의 하이퍼파라미터와 손실 함수를 높은 정확도로 빠르게 최적화할 수 있었다(R=0.92 및 NSE=0.85). 또한 미래 댐 유입량을 예측하기 위한 LSTM의 구조는 Forecasting 모형과 Proiection 모형으로 구분하여 두 모형의 장단점을 분석하였으며, 본 연구의 결과로부터 데이터 처리 단계가 모델 훈련의 효율성을 높이고 노이즈를 줄이는 데 효과적이고 미래 예측에 있어 LSTM 구조에 따른 영향을 확인할 수 있었다. 본 연구는 소양강 유역, 2020-2100년 기간 동안의 미래 예측에 적용되었다. 전반적으로, CIMIP6 데이터에 따르면 10%에서 50%의 미래 유입량 증가가 발생하는 것으로 확인되었으며, 이는 미래 강수량의 증가의 폭과 유사함을 확인하였다. 유입량 산정에 있어 신뢰할 수 있는 예측은 저수지 운영, 계획 및 관리에 있어 정책 입안자와 운영자에게 도움이 될 것입니다.

• Korean Journal of Agricultural Science
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• v.25 no.1
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• pp.79-88
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• 1998

This study was performed in order to apply to effective breeding of Korean native cattle on the molecular genetic level obtained from PCR and nucleotide sequencing analysis of BoLA DRB3 exon2 that has important roles in host immune defence. Genomic DNA used in this study was prepared from the blood of Korean native cattle in Korean Native Cattle Improvement Center of National Livestock Cooperation. The results obtained from this study are summarized as follows: 1. Genomic DNA extracted from the blood of Korean native cattle was subjected to electrophoresis on 1.5% agarose gel. Major band was bigger than 12.2kb, indicating that genomic DNA was well prepared for PCR. Amplified products of 284bp fragments was obtained the amplification of BoLA DRB3 exon2 gene by PCR. 2. Cloning of BoLA DRB3 exon2 of Korean native cattle with pCR2.1 vector was conformed by 300bp fragment from recombinent plasmid that restricted with enzyme digestion of EcoRI. 3. Homology of BoLA DRB3 exon2 alleles of parent was 82.0% between sire's alleles and 90.1% between dam's alleles. 4. In pedigree analysis using BoLA DRB3 exon2 gene, sequencing result of BoLA DRB3 exon2 genes showed inheritance by Mendelian mode through the parents to their offspring. 5. Taking together those experimental results, pedigree was confirmed on the basis of sequencing for the alleles of parents and offspring. This knowledge by the molecular biological approach could be served for the improvement of Korean native cattle.

• Korean Journal of Poultry Science
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• v.35 no.2
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• pp.131-136
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• 2008

This study was conducted to investigate the effects of dietary conjugated linoleic acid (CLA) and oil containing unsaturated fatty acid supplementation on egg production and quality in laying hens. Two hundred-eighty eight, 36 week old ISA brown commercial layer, were employed in a 5 week feeding trial. Dietary treatments are 1) BO (basal diet + 1% soybean oil + 1% oat), 2) BS (basal diet + 1% safflower oil + 1% oat), 3) BF (basal diet + 1% free fatty acid + 1% oat), 4) CD (basal diet + 1% CLA containing diglyceride + 1% oat), 5) CT (basal diet + 1% CLA containing triglyceride + 1% oat) and 6) CP (basal diet + 1% CLA by-product + 1% soybean oil). For overall period, hen-day egg production was not significant among treatments (P>0.05). Egg shell breaking strength at 3 weeks in CP treatment was significantly lower than BS, BF, CD and CT treatments (P<0.05) and that at 4 weeks in BO and CP treatments was significantly lower than others (P<0.05). Egg shell thickness at 3 and 4 weeks in CP treatment was significantly lower than BS, BF, CD and CT treatments (P<0.05). Egg weight at 3 and 4 weeks in CP treatment was significantly lower than others (P<0.05). Yolk height at 4 weeks in BF and CT treatments was significantly highest compared to BO, CD and CP treatments (P<0.05) and among BO, CD and CP treatments, that in BO and CD treatments was significantly higher than CP treatment (P<0.05). At 4 weeks, yolk color in CP treatment was significantly higher than BO and BS treatments (P<0.05). Haugh unit at 3 and 4 weeks in BO and CP treatments was significantly lower than others (P<0.05). In conclusion, supplementing CLA and oil containing unsaturated fatty acid for laying hens improved egg shell breaking strength, egg shell thickness, egg weight, yolk height, yolk color and haugh unit.

• The Journal of Korean Medical History
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• v.13 no.1
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• pp.103-110
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• 2000

Practical use of "So Mun Hyun Ki Won Byung Sik" on 'O Un Ju Byung' in "Dong Eui Bo Gam" has been analysed and is found that the author, Hur Jun of "Dong Eui Bo Gam", had applied "So Mun Hyun Ki Won Byung Sik" in explaining morphology of disease. Also, treatment and prescriptions were based on his personal opinion.

• The Journal of Korean Medical History
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• v.13 no.1
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• pp.111-127
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• 2000

Having looked at the effect of "Eui Hak Ip Mun", published at the end of the 16th century, on "Dong Eui Bo Gam", Author have concluded that there is difference in the view regarding the concepts of understanding human body and diagnosing disease. Also, "Dong Eui Bo Gam" is using "Eui Hak Ip Mun" selectively to establish a new medical system.