• 간호행정학회지
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• 제13권2호
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• pp.199-207
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• 2007

Purpose: Clinical characteristics and medical cost were analyzed according to the surgical procedures for intertrochanteric fracture in aged patients to assess the appropriateness of treatment expense and to find possibility of reducing the medical cost. Method: Variable for the statistical analysis were; the clinical characteristics, medical cost according to the surgical procedures, the treatment success rate, the total medical expense, and the average expense per case. SAS Package Version 8.02. was used to analyze the relevant data. Results: Operative procedures differ significantly according to the gender and by the location of institution. Only significant clinical variables according to the operative procedure were duration of general anesthesia and amount of blood transfusion. Average cost per treatment was the highest in the bipolar hemiarthroplasty followed by the gamma nail and hip compressing screw. Average cost for bipolar hemiarthroplasty was significantly higher than other surgical procedures. Conclusions: The difference in hospital costs for treatment of intertrochanteric fracture originates from the utilized surgical procedures, mostly by the materials used. The method of surgical treatment should be carefully determined by the purpose of the surgery, in order to improve the quality of medical care and also to reduce the hospital cost.

• 한국한의학연구원논문집
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• 제7권1호
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• pp.85-103
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• 2001

Objectives : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea(合穴) points in branches of the twelves meridians will be representative of measurements of the twelve meridians, to measure the electric potentials in twenty aged(TAG) and fifty aged(FAG) healthy volunteers groups when they were sleeping or awakening respectively, to do significance test for electric potential of meridian system among circadian rhythms(CR) and Sasang constitutions(SC). Methods : We selected who thirty healthy volunteers were diagnosed by a blood test, urine examination and differentiation of syndromes by five viscera among volunteers. When they were sleeping, their electric potentials of well and sea points in branches of the twelve meridians were simultaneously measured by physiograph. After a minute we measured them again, totally 5 times. And then when they were awakening, their electric potentials were measured 5 times by the above method. Results : Measurements were analyzed by statistical ANOVA test, we obtained that some of the electric potentials of TAG at sleeping significantly varied with CR, SC, and at awakening some of the electric potentials of FAG also significantly did with CR, SC.

• 한방안이비인후피부과학회지
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• 제12권1호
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• pp.241-253
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• 1999

The results of the study about comparison of Eastern-Western medicine on the Atopic dermatitis were as follows. 1. Atopic dermatitis is chronic eczematous dermatosis which have severe itching, characteristic eruption, easily occur region and pass on chronic relapsing progress and have family history of Atopic disease and hereditary disposition. 2. Atopic dermatitis assume an remarkable clinical aspect and it's diagnosis depends on family history and clinical symptom. 3. In all cases of Western medical treatment is nothing but a symptomatic treatment because can not find out certainly the cause of Atopic dermatitis. 4. Atopic dermatitis is belong to the category of the 'Naesun(내癬)', 'Taeryumchang(胎斂瘡)', 'Samanpoong(四灣風)' etc. in Oriental medicine. 5. The etiology and pathogenesis of Atopic dermatitis in oriental medicine are congenital defect(稟賦不足), internal accumulation of damp and heat(濕熱內鬱), improper diet(飮食不節), exogenous pathogenic factors(外邪侵襲), etc.. 6. The treatments of Atopic dermatitis in oriental medicine are thought effective clear up heat and remove dampness with febrifugal arld diuretic drug(淸熱利濕), invigorate the spleen to resolve dampness(健脾燥濕), nourish Um and blood to relave dryness(滋陰養血潤燥), etc..

• Pediatric Infection and Vaccine
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• 제4권2호
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• pp.282-287
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• 1997

Malaria due to Plasmodium vivax had been known as an indigenous protozoan disease in Korea. However, massive use of insecticides and improvement of sanitation for several decades have led to rapid reduction of malaria incidence, then it was recognized to have been almost eradicated in recent years. However in 1993, one case was reported in Phajoo, Kyungki-do, and then, reported cases have been increasing annually. Recently we encountered one case of malaria in a 3 year old male child living in Dorim-dong, Seoul, who had never been abroad and had no history of transfusion, drug abuse, and travel to endemic area in Korea. He had characteristic fever, chill and splenomegaly and was confirmed as Plasmodium vivax malaria with peripheral blood smear finding. He was successfully treated with hydroxy chloroquine and primaquine. We report this case with brief review of related literature.

• Journal of Preventive Medicine and Public Health
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• 제42권6호
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• pp.349-355
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• 2009

Biomarkers are characteristic biological properties that can be detected and measured in a variety of biological matrices in the human body, including the blood and tissue, to give an indication of whether there is a threat of disease, if a disease already exists, or how such a disease may develop in an individual case. Along the continuum from exposure to clinical disease and progression, exposure, internal dose, biologically effective dose, early biological effect, altered structure and/or function, clinical disease, and disease progression can potentially be observed and quantified using biomarkers. While the traditional discovery of biomarkers has been a slow process, the advent of molecular and genomic medicine has resulted in explosive growth in the discovery of new biomarkers. In this review, issues in evaluating biomarkers will be discussed and the biomarkers of environmental exposure, early biologic effect, and susceptibility identified and validated in epidemiological studies will be summarized. The spectrum of genomic approaches currently used to identify and apply biomarkers and strategies to validate genomic biomarkers will also be discussed.

• Childhood Kidney Diseases
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• 제17권2호
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• pp.29-34
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• 2013

Urine production is vital for the removal of certain waste products produced by metabolism in the body and for the maintenance of homeostasis in the body. The kidneys produce urine by the following three precisely regulated processes: filtration, reabsorption, and secretion. Urine is composed of water, certain electrolytes, and various waste products that are filtered out of the blood through the glomeruli. The physical features of urine are evaluated carefully to detect any abnormal findings that may indicate underlying diseases in the genitourinary system. A change in urine color may indicate an underlying pathological condition, although many of the causes of abnormal urine color are benign effects of medications and foods. A characteristic and specific odor may be the result of a metabolic disease rather than a concentrated specimen or a simple urinary tract infection. Although transient changes in urine output and nocturia are usually benign conditions, persistent abnormal findings require further workup, with a thorough medical history taking. This article presents many of the conditions that physicians may encounter and will help them in the diagnosis and in establishing a treatment plan.

• 한국식품영양과학회지
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• 제29권5호
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• pp.908-916
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• 2000

This study was undertaken to purify the anticoagulant polysaccharide from Pachymeniopsis elliptica. The anticoagulant compound (PE-2IVc-2-1) was isolated from the crude polysaccharide (PE-2) by the sequential steps such as ultrafiltration (PE-2IV), anion-exchange chromatography of DEAE-Toyopearl 650C(PE-2IVc), size-exclusion chromatography of Sepharose CL-6B (PE-2IVc), and HPLC Shodex OHpak column chromatography (PE-2IVc-2-1). The apparent molecular weight of purified polysaccharide (PE-2IVc-2-1) was approximately 710 kDa. It was mainly composed of galactose (48.6%) and 3,6-anhydrogalactose (44.0%) with 27.1% of sulfate residue, in addition a trace amount of xylose (3.6%), glucose (1.1%), mannose (1.1%), arabinose (0.8%) and fucose (0.8%). The IR spectrum of the polysaccharide showed the characteristic bands of S=O(1116.74 and 1143.17 $cm^{-1}$) and C-O-S (828.19 $cm^{-1}$) stretching, respectively. The anticoagulant effect of PE-2 in ex vivo was proportional to the concentration of intravenously injected dose, up to 100 mg/kg.

• 비교문화연구
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• 제35권
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• pp.59-78
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• 2014

This article is written on the ground that one of the major characteristics of Chinese New Period women's novels is about family dissolution and calling and it is examined based on analysis of "The Bathing Woman" by Tie Ning. In "The Bathing Woman", the family seems 'Regular' externally but it is actually fragmented internally. The author offers patriarchal perspective on 'Family' from the eyes of daughter of the family. The problems are classified into three categories. First, it is the problem of exclusiveness embedded in the essential characteristic of family represented by blood relation. Second, it is the research on the reason for family dissolution. Tie Ning finds the reason at 'Unmotherly mother, that is the lack of maternal instinct. Third, it is the expectation of the restoration of dissolved family. Tie Ning's indication of 'Family' is equal to 'Mother' and 'Mother' is the source and power that can heal and restore the dissolved family in her novel. It is expansion of maternal instinct represented by protection and caring into 'Practical action' and it is meaningful in a way that it expands the principle of maternal instinct and sublimates it into universal morality. However, it should not be overlooked that it could be another moral system that could suppress the females in other ways.

• Journal of Korean Neurosurgical Society
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• 제62권2호
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• pp.136-143
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• 2019

Moyamoya disease (MMD) is a progressive cerebrovascular disease with unknown etiology, characterized by bilateral steno-occlusive changes at the terminal portion of the internal carotid artery and an abnormal vascular network formation at the base of the brain. MMD has an intrinsic nature to convert the vascular supply for the brain from internal carotid (IC) system to the external carotid (EC) system, as indicated by Suzuki's angiographic staging. Insufficiency of this 'IC-EC conversion system' could result not only in cerebral ischemia, but also in intracranial hemorrhage from inadequate collateral anastomosis, both of which represent the clinical manifestation of MMD. Surgical revascularization prevents cerebral ischemic attack by improving cerebral blood flow, and recent evidence further suggests that extracranial-intracranial bypass could powerfully reduce the risk of re-bleeding in MMD patients with posterior hemorrhage, who were known to have extremely high re-bleeding risk. Although the exact mechanism underlying the hemorrhagic presentation in MMD is undetermined, most recent angiographic analysis revealed the characteristic angio-architecture related to high re-bleeding risk, such as the extension and dilatation of choroidal collaterals and posterior cerebral artery involvement. We sought to update the current management strategy for hemorrhagic MMD, including the outcome of surgical revascularization for hemorrhagic MMD in our institute. Further investigations will clarify the optimal surgical strategy to prevent hemorrhagic manifestation in patients with MMD.

• Journal of Genetic Medicine
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• 제16권1호
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• pp.23-26
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• 2019

Thrombophilia refers to inherited or acquired hemostatic disorders that result in a predisposition to blood clot formation. When combined with the hypercoagulable state that is characteristic of pregnancy, there is an increased risk of severe and recurrent pregnancy complications. Activated protein C resistance caused by factor V Leiden (FVL) mutation is known to be the most common cause of inherited thrombophilia in Caucasian population. FVL mutation has been related to pregnancy complications associated with hypercoagulation, e.g. miscarriage, intrauterine fetal demise, placental abruption, and intrauterine growth retardation. Although the FVL mutation is easily detected using molecular DNA techniques, patients who are heterozygous for this disorder often remain asymptomatic until they develop a concurrent prothrombotic condition. Because there are potentially serious effects of FVL mutation for pregnancy, and because effective treatment strategies exist, early detection and treatment of this condition might be considered.