• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.2
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• pp.85-100
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• 2010

Objectives: The purpose of this study was to evaluate diagnostic value of Transcranial Doppler Ultrasound about risk factor of stroke by comparing blood flow between patients with metabolic syndrome(MS group) and Normal group. Methods: 62 metabolic syndrome patients and 106 healthy adults were selected who had no cerebrovascular diseases, cardiovascular diseases and other systemic diseases. We measured the mean velocity(Vm), peak systolic velocity(Vs) and pulsatility index(PI) of MCA, ACA, PCA, VA, ICA in two groups using TCD. All subjects were divided by gender and age. Results: In comparing Ms group with normal group, Vm in the MCA, ACA, PCA, ICA and Vs in the MCA, ICA were lower in MS group. In all vessels, PI of MS group were higher than that of Normal group. In all vessels, Vm and Vs revealed negative correlation with age and PI revealed positive correlation with age. In 20-39 year olds, there was decrease in the Vs and Vm and increase of PI of MS group in comparison with normal group. There was significant difference in the Vm of PCA, ICA, Vs of MCA, PCA, ICA and PI of MCA, ACA. In 40-59 year olds, Vm in the MCA, ACA, ICA and Vs in the MCA, ACA were lower in MS group. PI in the MCA, ACA, PCA, ICA were higher in MS group. In 60-79 year olds, Vm of MCA, PCA, ICA was decreased in MS group than Normal group with no statistical signification. Vs in the MCA was lower and PI in the PCA was higher in MS group. In male, Vm of PCA and Vs of MCA were lower and PI of MCA, ACA, PCA, ICA were higher in MS group. In female, Vm of MCA, PCA, ICA and Vs of MCA, ICA were lower and PI of ACA, PCA, VA, ICA were higher in MS group. Conclusions: The significant difference in Vm, Vs, PI between MS group and normal group suggests hemodynamic disorder. Screening and prognosing high risk group can be done through TCD and this can be used to prevent stroke. More detailed study will be needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.6
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• pp.242-248
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• 2021

This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.

• Journal of Biomedical Engineering Research
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• v.16 no.2
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• pp.183-190
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• 1995

The use of ultrasound pulsed Doppler systems has become increasingly popular due to the advantages of easy measurements of blood velocity, volume blood blow, and irregularities of the circulatory system. However, the 2-D Doppler systems have several problems, such as range ambiguity, low signal to noise ratio, and slow frame rate. The mean frequency aliasing problem originating from the pulse repetition frequency is one of major limitations in pulsed Doppler systems. A conventional approach to resolve this problem is tracking the mean frequency close to and beyond the Nyquist frequency along the temporal axis. In this paper, a new concept of tracking the mean frequency along the spatial axis is proposed. The proposed technique is fault tolerant by nature and more suitable for multi gate and 2-D Doppler system than conventional methods.

• Journal of Biomedical Engineering Research
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• v.16 no.3
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• pp.279-288
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• 1995

Ultrasonic Doppler systems for the purpose of estimating blood flow velocity, blood flow volume, and flow imaging are commonly used due to advantages of non-invasive and real time observation. Specially, the technical developments of color flow mapping (2-D Doppler) systems have made a relatively rapid progress. However, the 2-D Doppler systems have several problems, such as the range ambiguity, low signal to noise ratio, and slow frame rate. The slow frame rate problem is resolved by using the spatial average which is a method to acquire more data samples for mean frequency estimation. In this paper, spatial average method using the 2nd order sampling instead of quadrature sampling is proposed. The experimental results show that the proposed methods have good performance and easy application to the color flow mapping system.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.124-127
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• 2002

Ceil embolisation technique has been used to treat the intracranial aneurysms. Microcoils inserted into the aneurysm sac induce the blood flow stagnation inside the aneurysm sac, which causes the thrombus formation and embolisation of aneurysm. Since the intraaneurysmal flow patterns affect the embolisation process, we want to measure the flow field for different locations of coil inside the aneurysm sac . Lateral aneurysm models are manufactured using rapid prototyping, and the velocity fields are measured using particle image velocitimeter. Distally blocked models showed less flow into the aneurysm sac comparing to proximally blocked models. Also blocking the neck of aneurysm showed better inflow blocking comparing to blocking the dome of aneurysm. These results suggest that distal neck should be the preferred locations of coil for aneurysm embolisation.

• Proceedings of the KIEE Conference
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• 2005.05a
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• pp.39-41
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• 2005

The population of diabetes is continuously increasing because of the economic development and the lifestyle modification. If diabetes become chronic condition, it can cause various complications. Among many other complications, diabetic foot is the most fatal issue since it may require amputation of the legs. Diabetic foot has three different types such as neuropathic, neuro-ischemic and ischemic. Among these types, patients of neuropathic foot experience sensory abnormality. Nerve conduction velocity (NCV) is used for diagnosing neuropathic foot but this method uses strong electric stimulus to cause severe pain to the patients In this study, two channel photo-plethysmography was used as noninvasive screening tool for distinguish neuropathic foot and normal group by observing blood flow of both finger and toe simultaneously.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.13 no.2
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• pp.123-140
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• 2009

The effect of a solute concentration difference on the osmotic transport of water through the semi-permeable membrane of a simple cell model is investigated. So far, most studies on osmotic phenomena are described by simple diffusion-type equations ignoring all fluid motion or described by Stokes flow. In our work, as the governing equations, we consider the coupled full Navier-Stokes equations which describe the fluid motion and the full transport equation that takes into account of convection and diffusion effects. A two dimensional finite difference model has been developed to simulate the velocity field, concentration field, and semi-permeable membrane movement. It is shown that the cell swells to regions of lower solute concentration due to the uneven water flux through the semi-permeable membrane. The simulation is applied on a red blood cell geometry and the relevant results are presented.

• Proceedings of the KSME Conference
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• 2000.04b
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• pp.531-534
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• 2000

The objective of this investigation is to find effects of the pulsatile flow on the morphological changes of the endothelial cell(E.C.) in blood vessel. The shear flow experiment system is used to get the morphological changes of the E.C. The shapes of E.C. are simulated by the cosine curves and computer simulation is used to calculate the pressure and shear stress fields on the E.C. The inlet boundary condition is given from the measured velocity data of femoral artery. The endothelial cells reduce their heights in the flow field so as to reduce the pressure and wall shear stress on the surface. As the exposed time increases, the shear stress and pressure on the E.C. are reduced under the pulsatile flow. The shear stresses on the cell surface show the minimum values during the deceleration phase.

• Proceedings of the KSME Conference
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• 2003.11a
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• pp.741-746
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• 2003

The main objective of present study is to obtain information for flow characteristics, such as velocity and wall shear stress, of bifurcation in blood vessel. Branch flows for Newtonian fluids are simulated by using Fluent V.6.0. The numerical simulations are carried out for five cases divided by different values of bifurcation angle and area ratio. As a result of simulation, high wall shear stress is appeared at the bifurcated region. As increasing bifurcation angle, pressure drop is increasing. In addition, as the area is decreasing, pressure drop and wall shear stress is increasing.

• Transactions of Materials Processing
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• v.24 no.2
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• pp.89-94
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• 2015

Medical catheter tubes are disposable devices that are inserted into the body cavities such as the pleura, trachea, esophagus, stomach, urinary bladder, ureter, or blood vessels for surgical procedures. Each hole of the inner tube is called a lumen, which is used as a passage for drug injections, waste discharge, polypus removal, blood transport, or injection of a camera or sensor. The catheter tube is manufactured by extrusion. The flow in the inner extrusion die affects the thickness and diameter of the tube. In the current study computer simulation of flow in an extrusion die for catheter tubing was performed. Velocity, pressure, shear rate, and shear stress were investigated and the die design was examined.