• KOREAN JOURNAL OF CROP SCIENCE
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• v.48
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• pp.24-30
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• 2003

Plant fats and oils contain phytosterols as naturally occurring constituents, which are present in pure or esterified form, or conjugated as glycosides. The predominant phytosterol is sitosterol and minor components are campesterol, stigmasterol, $\Delta^7$-avenasterol and brassicasterol. They play a key role in cell membrane function of plants as cholesterol in animals. Phytosterols have been known for many years for their properties for reducing blood cholesterol levels, as well as their other beneficial health effects for cancer preventive biological-active substances. The objective of this paper is to present a description of the recent advances in phytosterols for future research.

• The Korean Journal of Food And Nutrition
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• v.9 no.4
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• pp.366-371
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• 1996

The purpose of this study was to investigate blood pressure and blood constituents in middle-aged men obesity. All the measurements were taken from 1524(obese 453, control 1071) man's subjects. The body mass index BMI in obese group and control was 26.6$\pm$1.4kg/$m^2$ and 22.2$\pm$1.9kg/$m^2$ respectively. The mean systolic and diastolic blood pressure in obese group were significantly higher than control(p<0.001). The concentrations of serum total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol and atherogenic index in obese group were 202.1$\pm$34.7mg/dl, 210.0$\pm$121.8mg/dl, 43.4$\pm$10.3mg/dl, 116.7$\pm$33.5mg/dl, 3.8$\pm$1.2, respectively. There was significance in the relation between cholesterol, triglyceride, LDL-cholesterol and BMI. The frequency of dyslipidemia (hypercholesterolemia and hypertriglyceridemia) in obese group was significantly more than control(p<0.001).

• Journal of the East Asian Society of Dietary Life
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• v.6 no.3
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• pp.425-434
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• 1996

The purpose of this study was to investigate of the dietary life and nutritional status of the Buddhist priests. Dietary life, the state of prepare a meal and menu are carried out through the questionnaire and the nutritional status is carried out through the analysis of the constituents of the blood. The results of this study can be summarized as follows. 1. The traditional temple's foods undergo a change with the variety and westernization of dietary life. 2. Buddhist priests take a carbohydrate centered meal and the intake of protein and lipid is tendency to lack, but the intake of vitamin and mineral is sufficient with various vegetables. 3. The content of the lipid compoents and glucose of blood are low and they are free from the danger of geriatric diseases but the content of triglyceride is very higher than the healthy general adults. Therefore it is necessary to improve the nutritional status of the buddhist priests with decrease the intake of rice and increase the various side dish and to develop the standard menu for the Buddhist priests.

• Journal of Ginseng Research
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• v.42 no.3
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• pp.255-263
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• 2018

Orally administered ginsengs come in contact with the gut microbiota, and their hydrophilic constituents, such as ginsenosides, are metabolized to hydrophobic compounds by gastric juice and gut microbiota: protopanxadiol-type ginsenosides are mainly transformed into compound K and ginsenoside Rh2; protopanaxatriol-type ginsenosides to ginsenoside Rh1 and protopanaxatriol, and ocotillol-type ginsenosides to ocotillol. Although this metabolizing activity varies between individuals, the metabolism of ginsenosides to compound K by gut microbiota in individuals treated with ginseng is proportional to the area under the blood concentration curve for compound K in their blood samples. These metabolites such as compound K exhibit potent pharmacological effects, such as antitumor, anti-inflammatory, antidiabetic, antiallergic, and neuroprotective effects compared with the parent ginsenosides, such as Rb1, Rb2, and Re. Therefore, to monitor the potent pharmacological effects of ginseng, a novel probiotic fermentation technology has been developed to produce absorbable and bioactive metabolites. Based on these findings, it is concluded that gut microbiota play an important role in the pharmacological action of orally administered ginseng, and probiotics that can replace gut microbiota can be used in the development of beneficial and bioactive ginsengs.

• Korean Journal of Plant Resources
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• v.35 no.6
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• pp.713-719
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• 2022

Platycodon grandiflorum and Glycyrrhiza uralensis contain several bioactive compounds, such as saponin, oleanolic acid, and flavone. P. grandiflorum and G. uralensis have traditionally been used to treat disorders related to blood pressure, diabetes, and counteracting poison, and they have antinociceptive and antiinflammatory properties. However, the validity of complex saponin's vasodilatory effect has not been scientifically investigated. Therefore, this study explores the vasodilatory effect of complex saponin extracted from P. grandiflorum and G. uralensis mixture extract on rabbit carotid arteries. To this end, arterial rings with intact or damaged endothelium were used in an organ bath experiment and contracted by endothelin. Complex saponins, the major active constituents of P. grandiflorum and G. uralensis mixture extract, exhibited a moderate vasodilatory effect on the rabbit's basilar arteries. Therefore, treatment with complex saponin extracted from P. grandiflorum and G. uralensis mixture extract may selectively accelerate cerebral blood flow through basilar arterial dilation. Overall, the findings suggest that the extracted complex saponins can serve as vasodilator sources.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.11
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• pp.1642-1645
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• 2005

This study was conducted to investigate the effects of Biotite V supplementation on growth performance, nutrients digestibility and blood constituents and to evaluate whether Biotite V could replace an antibiotics in growing pigs diet. One hundred twenty pigs with initial body weight of 18.35${\pm}$0.15 kg were used in a 28 days growth trial. Pigs were allotted to four treatments by sex and body weight in a randomized complete block design. There were six replicate pens per treatment and five pigs per pen. Four dietary treatments were: 1) NC (basal diet without antibiotics), 2) PC (basal diet+0.1% CTC), 3) NCBV (NC diet+0.5% 200 mesh Biotite V) and 4) PCBV (PC diet+0.5% 200 mesh Biotite V). Through the entire experimental period, ADG tented to increase in NCBV and PCBV treatments compared to NC and PC treatments respectively, but no significant differences were observed (p>0.05). ADFI was slightly lower in NCBV and PCBV treatments than that in NC and PC treatments without significant differences (p>0.05). Gain/feed in PC and PCBV treatments was improved significantly compared to NC treatment (p<0.05). N and Ca digestibilities were higher in PCBV treatments than those in PC treatment (p<0.05). DM and P digestibilities were not affected by the addition of Biotite V (p>0.05). RBC, HCT, Hb, lymphocyte and monocyte were increased numerically in NCBV and PCBV treatments compared to NC and PC treatments (p>0.05). WBC was lower in treatment groups than that in NC treatment, but no significant differences were observed (p>0.05). In conclusion, dietary supplementation of Biotite V can better the gain/feed and some of the nutrients digestibilities in growing pigs. It has a possibility to replace antibiotics in swine diet.

• Asian-Australasian Journal of Animal Sciences
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• v.8 no.3
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• pp.241-247
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• 1995

The aim of the present study was to investigate the effect of internal parasites on growth rates of Thai Native (TN) and crossbred (75% TN $\times$ 25% Anglo-Nubian, AN and 50% TN $\times$ 50% AN) goats (undrenched, drenched every 3 weeks or at 9 weeks) in village environments in southern Thailand in a humid tropical climate. There was no significant (p > 0.05) difference in growth rate ($g/kg^{0.75}/d$) between the genotypes during unsupplemented grazing (0-64 days of the experimental period). However, during supplementary feeding (64-127 days) and throughout the period (0-127 days) TN goats had significantly (p < 0.01) lower growth rates compared with 75% TN $\times$ 25% AN and 50% TN $\times$ 50% AN goats. There was no (p > 0.05) significant difference in growth rates between 75% TN $\times$ 25% AN and 50% TN $\times$ 50 % AN goats. The growth rates of goats drenched every 3 weeks were significantly (p < 0.01) higher than those undrenched or drenched at 9 weeks. The results of this study also indicate that drenching alone did not result in increased weight gain except when the nutritional status was also improved. Parasitic infection affected some blood constituents, such as pack cell volume, haemoglobin, total protein and albumin. This resulted in lower growth rates for control groups and goats drenched at 9 weeks compared to those of goats drenched every 3 weeks.

• Journal of Nutrition and Health
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• v.26 no.8
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• pp.953-966
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• 1993

The purpose of this study is to investigate the nutritional status and blood constituents of the diabetics by obese index. All the measurements were taken from 501 (male 202, female 299) diabetics. Subjects were devided into 4 groups(underweight, ideal body weight, overweight, obesity) by obese index. 1) Energy intake was 1670-1900 Kcal in male diabetics and 1460-1560 Kcal in female diabetics. 2) In male diabetics, intakes of dietary cholesterol, protein food and polyunsturated fatty acid were significantly higher in underweight group than the other three groups. 3) In male diabetics, obese indices of RBW, BMI, WHR were observed to have significant positive correlation with alcohol intake(r=0.15, p<0.05). In female diabetics, WHR was observed to have a significant positive correlation with cholesterol intake(r=0.21, p<0.001). 4) In male diabetics, obese indices of RBW, BMI were observed to have significant negative correlations with total fatty acid(r=-0.16, -0.15), PUFA(r=-0.21, -0.20), total 6 fatty acid (r=-0.20, -0.19), and linoleic acid(r=-0.20, -0.19). In female diabetics, obese index of weight was observed to have significant negative correlations with total fatty acid(r=-0.13), saturated fatty acid(r=-0.13). 5) HDL (5) of diabetics was lower than normal level in all weight groups except underweight. VLDL(5) and serum TG(mg/dl) of diabetics was higher than normal level in all weight groups except underweight. 6) In male diabetics, obese indices of weight, RBW, BMI were observed to have significant negative correlations with HDL(r=-0.44, -0.29, -0.35), positive correlation with VLDL(r=0.39, 0.24, 0.30), and positive correlations with serum TG(r=0.25, 0.22, 0.24).

• Animal Bioscience
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• v.34 no.2
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• pp.285-294
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• 2021

Objective: This study was conducted to investigate the supplementary effect of a phytogenic blend (SPA: a mixture containing fermented Schisandra chinensis pomace, fermented Pinus densiflora needle extract, and Allium tuberosum powder in the ratio of 2:2:1) on egg production, egg quality, blood constituents, and visceral organs in laying hens. Methods: A total of 135 Hy-line brown laying hens (48-wk-old) were randomly allocated to three dietary treatments with 5 replicates of 9 hens. The control group (CON) was fed a basal diet (no exogenous SPA addition) and the experimental groups were fed the basal diet containing SPA at the level of 0.1% and 0.3% for 6 weeks. Results: The feed intake was significantly improved in SPA supplemented groups as compared with the control (p<0.05). However, egg production, daily egg mass, and feed conversion ratio were not different among the dietary treatments (p>0.05). For egg quality traits, only Haugh unit (HU) was significantly improved in SPA (0.3%) (p<0.05) as compared with other groups. However, HU was not affected during 4-wk of storage at 18℃ among the dietary treatments (p>0.05). Furthermore, SPA supplementation did not affect the blood biochemical constituents except for the phosphate content, which was significantly higher in SPA groups than the CON group (p<0.05). There were no significant differences in visceral organ characteristics and immune indicators (immunoglobulin A [IgA], IgG, and IgM) in SPA or CON groups. Conclusion: This study suggested that the supplementation of SPA may have beneficial effects on feed intake and egg quality in laying hens.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.1
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• pp.21-29
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• 2001

An experiment was conducted with twenty crossbred male lambs to assess the effect of cotton (Gossypium) seed meal (CSM) on blood constituents and immunity. Lambs were randomly assigned to a reference diet (30% deoiled peanut meal, DPNM) and four test diets containing 40% of either raw, 45 minutes cooked, 1% $Ca(OH)_2$ and iron (1 free gossy-pol, FG : 0.3 Fe) treated CSM (replacing approximately 50%, reference concentrate mixture). These isonitrogenous and isocaloric concentrate mixtures were fed to meet 80% of protein requirements (NRC, 1985) along with ad lib maize hay for 180 days. Blood was collected at 60, 120 and 180 days post feeding. The lambs were sensitized with Brucella abortus S99 antigen after 140 days and were subjected to ELISA and delayed type hypersensitivity. Blood haemoglobin, erythrocyte count, leucocyte count, total protein, total albumin, total globulin, urea, creatinine concentration and aspartate aminotransferase activity in lambs fed on raw or processed CSM were comparable to the values of reference lambs. The higher (p<0.01) blood glucose levels observed in CSM fed lambs at 60 days of feeding was latter reduced to the levels comparable with those on reference diet at 120 and 180 days of feeding. The alanine amino transferase activity was lower in lambs fed raw and cooked CSM containing diets at 120 and 180 days of feeding. A marginal increase in serum iron and alkaline posphatase activity was observed in iron treated group and raw CSM fed lambs, respectively. The humoral immune response and DTH reactivity was lower (p<0.05) in lambs fed raw CSM (consuming 302.83 mg FG/day). Cooking, $Ca(OH)_2$ and iron treatment of raw CSM showed a positive response in alleviating the suppression of immune response owing to the reduced consumption of FG by 40.19, 17.40% and 26.73%, respectively in these diets. The present study thus indicated that consumption of 40% raw CSM (302.83 mg FG/day) though did not affect majority of the haematological and blood biochemical parameters, but markedly suppressed the immune mechanism of lambs.