• 대한지역사회영양학회지
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• 제2권5호
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• pp.695-700
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• 1997

This study was conducted to investigate the effect of an energy restriction program on the weight loss and changes of the biochemical nutritional status for 35 obese women. The energy restriction program took place over a 3-week period that was devided into two parts. The first part consisted of 750-800kcal diet and the second part of 800-1000kcal. Subjects were provided a low energy formula and a menu for the recommended diet. Anthropometric and biochemical measurement before and after the energy restriction program were estimated. Mean weight loss was 3.0kg, accordingly the obestiy rate was lowered from 40.2 to 34.4, BMI from 29.2 to 28.9 and fat weight from 23.3kg to 21.0kg( <0.01. <0.05). Waist circumference loss was most prominent(4.4%) compared to triceps(21% loss)and hip circumference(2.2%loss). Mean RBC count, hemoglobin and hematocrit were significantly lowered( <0.01) but they were in the normal range. Systolic blood pressure was significantly decreased from 124.1mmHg to 113.1mmHg . Mean SGOT and SGPT were lowered from 29.3u/L to 20.0u/L and from 28.7u/L to 16.6u/L, respectively. It seems that the 3 weeks of energy restriction program used in this study was effective in improving anthropometric measurements without producing deficiency of iron or other susceptible nutrients.(Korean J community Nutrition 2(5) : 695-700,1997)

• 대한수의학회지
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• 제35권3호
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• pp.437-445
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• 1995

과일 및 채소류의 곰팡이 억제제로 개발된 captafol은 인간 및 동물에서의 독성작용은 많이 보고된 바 있으나 이들의 독작용을 완화시키거나 치료할 수 있는 제제에 대한 연구는 별로 알려진 바 없다. captafol에 의한 혈액학 및 혈청 생화화적 변화에 따른 cysteine의 방어 작용을 확인할 목적으로 랫트에 5mg/kg 용량의 captafol을 1회 복강 투여하고 동시에 5, 58, 290 및 580mg/kg cysteine을 각각 투여하고 체중의 변화, 부검소견, 절대장기중량, 혈액학 및 혈청 생화학적 소견을 비교 분석 하였다. captafol 단독 투여군에서는 체중 및 간 장기중량 감소, 복강내 장기들의 섬유소에 의한 유착 및 복수 등이 현저하였으며 적혈구 수, hemoglobin 농도, 혈청 AST의 증가가 인정되었으며 또한 혈청 인지질 함량 감소가 확인되었다. 한편, cysteine 58mg/kg 이상의 용량군에서는 복강내 장기들의 유착 및 복수가 확인되지 않았으며 장기중량, 혈액학 및 혈청 생화학적 소견에서도 정상을 나타내었다. 이 연구 결과는 captafol의 중독증상에 대해 cysteine 및 sulfhydryl군을 가진 물질은 그 증세를 감소시키거나 완화시킬 수 있는 효과가 있음을 보여주고 있다.

• 대한정형외과스포츠의학회지
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• 제7권1호
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• pp.45-49
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• 2008

목적: 하프코스 마라톤 달리기 후에 체내의 생리적 변화를 관찰하여 휴식 기간에 따른 회복 양상을 확인하고자 한다. 대상 및 방법: 하프코스 완주자 13명( 남자 12명, 여자 1명)을 대상으로 하였으며, 평균 연령은 44세(범위: $38{\sim}54$)이었으며 신장은 평균 166 cm (표준편차 6.5), 몸무게는 평균 68 kg(표준편차 7.3)이었다. 생화학적 검사항목은 운동 후 근육 및 심장에 영향을 미치는 혈청효소인 aminotransferases (AST, ALT), CK-MB, Troponin-I 그리고 신장 기능 및 체내의 전해질 균형 상태를 확인할 수 있는 BUN, Creatinine, Na, K의 변화를 확인하였으며, 검사 방법은 출발 전, 완주 직후 및 2일 후, 완주 후 2주에 채혈하여 검사치의 변화의 양상을 확인하였다. 결과: 모든 검사 항목에 있어 측정 시점에 따른 측정 결과는 정상범위 내의 변화를 보였다. 측정 시점에 따른 유의한 변화를 보이지 않았던 검사항목은 ALT (p=0.914) 및 Troponin I (p=0.354)이었으며, BUN, Cr. Na. K등 신장 기능 및 체내의 전해질 균형상태를 반영하는 검사는 완주 직후 증가되었다가 2일 째에 출발전의 수치로 회복되었으며, 근육 및 심장에 영향을 주는 AST 및 CK-MB의 경우 완주 직후 증가된 수치가 2일째까지 유지되거나, 더욱 증가되었다가 2주 후 검사 상 출발전의 수치로 회복되는 양상을 보였다. 결론: 장거리 달리기를 한 후 탈수 현상으로 인한 초기 신장 효소 변화는 2일 정도에 회복이 되었으며, 근육 및 심장의 피로 효소는 약 2주 정도의 시간이 지나야 회복되었다. 따라서 하프코스마라톤을 뛴 후 정상적인 회복을 위해서는 음주경력, 흡연경력 및 달리기 경력에 상관없이 약 2주간의 회복기를 거치는 것이 필요할 것으로 생각되었다.

• 대한지역사회영양학회:학술대회논문집
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• 대한지역사회영양학회 2005년도 10th Anniversary International Symposium
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• pp.80-80
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• 2005

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2004년도 KSOT/KEMS Fall Annual Meeting
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• pp.136-136
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• 2004

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2004년도 KSOT/KEMS Fall Annual Meeting
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• pp.135-135
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• 2004

• Toxicological Research
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• 제7권1호
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• pp.51-59
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• 1991

The purpose of the present study was to investigate the effects of non-watering, fasting and non-watering fasting for 16-17 hrs on haematological and biochemical parameters in SD rats. 1. Liver weight was decreased in the order of in the fasting group, non-watering fasting group and non-watering group in both sexes. 2. In fasting group and non-watering fasting group, haematologic parameters of male (HGB and MCH) and femal (MCHC) were trends to decrease compared with normal feeding & watering group. 3. In the differential leucocyte counts, there were no significant differences compared with noraml feeding % watering group.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2007년도 추계국제학술대회 및 컨퍼런스
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• pp.629-629
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• 2007

• Environmental Analysis Health and Toxicology
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• 제2권1_2호
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• pp.43-53
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• 1987

Among the environmental toxic metals, cadmium and lead compounds are very hazard for human health because these may affect the biological function of human body and furthermore enhance the cause of various disease. In recent years, as the view of environmental toxicology, the combination of toxic metals suffering human health is especially significant cadmium chloride (10 mg/kg P. 0., 1 mg/kg I.P.) and lead acetate (20 mg/kg P.O., 2 mg/kg I.P.) were administered to rats for 4 weeks on alternate days and then examined the effect of these on body weight, tissue weight and also biochemical function in blood and tissue were investigated and comparision of the two experimental groups such as single and combined administration. According to the results of this experiment, accumulation of heavy metals increased and biological metabolic function grew worse but, in tissue, toxic effect decreased by combined administration and intraperitoneal administration was more toxic than per OS.

• 한국환경성돌연변이발암원학회지
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• 제21권2호
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• pp.156-163
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• 2001

Vanadium has been known as environmental polluants resulted from the burning of fossil fuels in nature. It led to toxic responses by prooxidant activity, inducing free radicals and the accumulation in the tissues. Recently, there has been growing interest in an essential nutritional requirement of vandium and especially the treatment of diabetes. But because of its strong toxicity, thease chemicals have narrow safety margin. In order to reduce metal toxicity, and increase absorption and biological activities, metal ions such as selenium and chromium were uptaken in yeast cells. In this study, Vanadium yeast was prepared by uptaking vanadate in yeast cells. Vanadate induced hematological and biochemical changes in the experimental rat blood were inhibited by the treatments of vanadium yeast. Lipid peroxidation and catalase activity were significantly increased in kidney and liver after a single intraperitoneal injection of vanadate to rats. However, these observations were apparently reduced in the vanadium yeast treated group. Vanadium amount in blood, kidney and liver after a single intraperitoneal injection of vanadium yeast was significantly reduced than that of vanadate treated group. In conclusion, vanadium yeast uptaken vanadate in yeast cells could reduce toxic effects of vanadate.