• 생명과학회지
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• 제19권10호
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• pp.1374-1381
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• 2009

본 연구는 남성 음주자의 나이대별 생리학적 변수들에 어떠한 차이가 있는지를 연구하였다. 30대 남성들은 waist-hip ratio, 좌 우 심장-발목 혈관지수, 좌 우 발목-상완지수, 아밀라제, hs-CRP, CPK가 가장 낮았고 체중, IL-6, 좌 우 안와혈압, 혈색소, 적혈구수, 적혈구 분포도, ALT, 총 콜레스테롤, 중성지방, 페르틴 농도는 높게 나타났다. hs-CRP, CPK는 40대 음주남성에서 높았지만 페리틴 농도는 반대였다. 50대 음주남성에서는 WHR이 높았으며 이완기 혈압, 좌 우 안와혈압, 호산구와 아밀라제 농도는 높게 나타냈다. 60대 음주남성에서는 좌 우 심장-발목 혈관지수, 평균 혈색소 농도, $\gamma$-GTP, RF, AFP, PSA의 농도는 높았으며, 체중, 이완기 혈압, 좌 우 안와혈압, 혈색소, 혈소판, 백혈구, 적혈구 분포지수, 호산구, 단구, 아밀라제 중성지방, CPK 농도 변화에서는 높게 나타났다. 이러한 결과를 볼 때 음주는 남성들에 있어 나이대별로 다양한 생리학적 변화를 유도 할 것으로 사료된다. 향후 음주가 성별, 즉 남녀 간에 미치는 생리학적 영향의 차이에 대한 연구 역시 더 필요할 것으로 생각된다.

• Journal of Nutrition and Health
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• 제37권7호
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• pp.557-565
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• 2004

This study was conducted to assess the effect of nutrition counseling for postoperative female breast cancer patients (N = 38). In baseline survey, we investigated the nutrition parameters by measuring anthropometric and biochemical blood index and assessing nutrient intake using recall method. Individual nutrition counseling was performed 3 times with 2 - 3 weeks intervals. Patients were offered nutrition information related to breast cancer and desirable life style after cancer operation. The effects of counseling program were assessed 2 month later. Of biochemical parameters, serum total cholesterol level was significantly reduced after nutrition counseling program. Nutrient intakes of postoperative breast cancer patients were generally below the RDA level at the baseline survey. After nutrition counseling, mean daily intake of total energy, protein, calcium were significantly elevated. Of dietary habit, meal regularity and control of portion size were improved and fruits and vegetables intake were significantly increased after nutrition counseling. Control of fatty food intake and alcohol drinking were significantly improved after nutrition counseling program. Score of general nutrition knowledge and knowledge about breast cancer, were significantly increased after nutrition counseling from 2.1 to 3.2 and from 2.3 to 3.8, respectively. It can be postulated that the dietary habit and nutrients intake of postoperative breast cancer patients can be improved by individual nutrition counseling program. In further study, the systematic group nutrition counseling program is needed.

• 대한수의학회지
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• 제54권4호
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• pp.233-238
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• 2014

The present study was performed to evaluate the effect of medicinal plant extract on relieving hangovers in mice administered alcohol. The animals were divided into three groups. Each group was treated with fermented plant extract, non-fermented plant extract, or water 30 min after consuming ethanol (2 mL/kg). A locomotor activity test showed that all groups had decreased motor activity until 40 min after plant extract administration. The mice treated with water had lower motor activity until 100 min post-administration. However, the group treated with non-fermented plant extract showed increased motor activity 40 min post-administration, and the higher activity level was maintained until 120 min post-administration. The animals treated with fermented plant extract had a level of motor activity between those of the groups treated with water or non-fermented plant extract. Blood was collected from each mouse 120 min post-administration and aldehyde concentration was measured. The group treated with non-fermented plant extract had a significantly higher (p < 0.05) aldehyde concentration than the other groups. These results demonstrate that the non-fermented medicinal plant extract helped alleviate hangovers 40 min after administration by reducing aldehyde concentrations in the blood.

• Journal of Nutrition and Health
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• 제26권8호
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• pp.953-966
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• 1993

The purpose of this study is to investigate the nutritional status and blood constituents of the diabetics by obese index. All the measurements were taken from 501 (male 202, female 299) diabetics. Subjects were devided into 4 groups(underweight, ideal body weight, overweight, obesity) by obese index. 1) Energy intake was 1670-1900 Kcal in male diabetics and 1460-1560 Kcal in female diabetics. 2) In male diabetics, intakes of dietary cholesterol, protein food and polyunsturated fatty acid were significantly higher in underweight group than the other three groups. 3) In male diabetics, obese indices of RBW, BMI, WHR were observed to have significant positive correlation with alcohol intake(r=0.15, p<0.05). In female diabetics, WHR was observed to have a significant positive correlation with cholesterol intake(r=0.21, p<0.001). 4) In male diabetics, obese indices of RBW, BMI were observed to have significant negative correlations with total fatty acid(r=-0.16, -0.15), PUFA(r=-0.21, -0.20), total 6 fatty acid (r=-0.20, -0.19), and linoleic acid(r=-0.20, -0.19). In female diabetics, obese index of weight was observed to have significant negative correlations with total fatty acid(r=-0.13), saturated fatty acid(r=-0.13). 5) HDL (5) of diabetics was lower than normal level in all weight groups except underweight. VLDL(5) and serum TG(mg/dl) of diabetics was higher than normal level in all weight groups except underweight. 6) In male diabetics, obese indices of weight, RBW, BMI were observed to have significant negative correlations with HDL(r=-0.44, -0.29, -0.35), positive correlation with VLDL(r=0.39, 0.24, 0.30), and positive correlations with serum TG(r=0.25, 0.22, 0.24).

• 한국농촌생활과학회지
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• 제9권1호
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• pp.19-31
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• 1998

The purpose of this study was to compare the consciousness health status and food habit for farmers in Korea. Eight hundred persons were surveyed by rural leader of RDA, composed with 35.1% of male and 64.9% of female. Data collection includes height weight and blood pressure by measuring method and personal & family situation by interview for influential factor of health status and food habit. The questionnaire was included dietary habit of salt, sugar, dietary fiber and fat intake and other behavior questions related with diet. The subjects were composed 32.5% of elementary school graduated and 50% of middle size farming. Of the all subjects, 54% of were rice planted farming mainly and 19 were over 65 year-aged group. In the concept of disease prevalence. gender difference was exist, liver and heart complains were more frequency in male and waist pain and urinary complain in female, shoulder pain and nervousness were frequently prevalent to all group of farmers. The hypertension prevalence of farmers were 16% by measuring blood pressure, but consciousness of hypertension was very low (5%). The correlation of health status with personal factors were analysed, body weight, number of family, education level, and working level were significant with CMI score and Farmers' syndrome score. The food habit status was negatively correlated with weight and BMI, age was negatively correlated with CMI score and farmers' syndrome. The consciousness of health status and food habit score were significantly correlated with smoking and alcohol drinking. It concludes that good food habit contribute wellness of health. Nutrition education for better food habit would be helpful on health status.

• Journal of Korean Biological Nursing Science
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• 제23권1호
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• pp.31-42
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• 2021

Purpose: This study was performed to assess the level of blood glucose and to identify poor glycemic control groups among patients with type 2 diabetes mellitus (DM). Methods: Data of 1,022 Korean type 2 DM patients aged 30-64 years were extracted from the Korea National Health and Nutrition Examination Survey VII. Complex samples analysis and a decision-tree analysis were performed using the SPSS WIN 26.0 program. Results: The mean level of hemoglobin A1c (HbA1c) was 7.22±0.25%, and 69.0% of the participants showed abnormal glycemic control (HbA1c≥6.5%). The characteristics of participants associated with poor glycemic control groups were presented with six different pathways by the decision-tree analysis. Poor glycemic control groups were classified according to the patients' characteristics such as period after DM diagnosis, awareness of DM, sleep duration, gender, alcohol drinking, occupation, income status, low density lipoprotein-cholesterol, abdominal obesity, and number of walking days per week. Period of DM diagnosis with a cut-off point of 6 years was the most significant predictor of the poor glycemic control group. Conclusion: The findings showed the predictable characteristics of the poor glycemic control groups, and they can be used to screen the poor glycemic control groups among adults with type 2 DM.

• Journal of Preventive Medicine and Public Health
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• 제24권4호
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• pp.496-506
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• 1991

모 철강공장에서 1990년 8월 27일부터 9월 6일까지 실시되었던 정기 특수건강진단에 참여한 근로자 중 평균 소음노출이 $91.8{\pm}5.2dB(A)$인 고소음부서 기능직 근로자 1,034명과 $75.2{\pm}4.6dB(A)$인 저소음부서 기능직 근로자 390명 사이에 고혈압(수축기 160mmHg 이상 또는 이완기 100mmHg 이상) 유병률을 비교하고, 청력손실(1,000Hz에서 25dB 이상 또는 4,000Hz에서 40dBA이상) 여부와 고혈압 유병률과의 관계를 관찰하여 다음과 같은 결과를 얻었다. 고소음부서와 저소음부서 사이에 평균 수축기 및 이완기 혈압의 차이를 보이지 않았다(p>0.05). 고소음부서와 저소음부서 사이의 고혈압 유병률은 통계적으로 유의하지는 않았으나 39세 이내의 연령군에서는 고소음부서에서 더 높았으며, $40{\sim}49$세 사이의 연령군에서는 차이가 없었고, 50세 이상의 연령군에서는 오히려 저소음부서에서 높은 경향을 보였다. 고혈압 유병률은 고연령군에서 보다 저연령군의 청력손실군에서 정상 청력군에 비해 통계적인 유의성이 없었으나 더 높은 경향을 보였다. 청력손실, 비만도지수, 연령, 음주습관 및 고혈압 가족력이 이완기 혈압의 예견지표였다(p<0.02). 청력손실은 특히 40세 이전의 연령군에서 주요 이완기혈압 예견지표로 나타났다(p<0.01).

• 생물정신의학
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• 제8권2호
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• pp.258-265
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• 2001

Objectives : Chronic alcohol consumption has been known to result in various neurocognitive deficits. Many neuropsychological studies revealed that the major disturbances occurred in the executive function, learning and short-term memory, visuospatial performance function, perceptuo-motor skills, and abstraction and problem solving abilities. This study was done to identify which cognitive areas might be mainly affected. Methods : The cognitive disturbance was evaluated using the Korean Version of the Mini Mental State Examination(MMSEK) and the 7 Minute Screen(7MS) in male inpatients with alcohol dependence(N=3 : as well as in age and education level matched healthy male controls(N=30). Four individual tests of the 7MS were consisted of the Benton Temporal Orientation Test, the Enhanced Cued Recall, the Clock Drawing and the Category Fluency. Results : 1) The average scores of four individual test of the 7MS for the alcoholics were $2.77{\pm}4.38$ for the Benton Temporal Orientation Test, $13.90{\pm}2.02$ for the Memory Test(the Cued Recall $6.77{\pm}1.94$, the Uncued Recall $7.10{\pm}2.45$), $5.84{\pm}1.86$ for the Clock Drawing, and $12.58{\pm}3.29$ for the Category Fluency. Except the Benton Temporal Orientation Test, there were statistically significant differences between test scores of alcoholics and those of controls(p<0.01). 2) The alcoholics who had MMSE-K score <24 were 9.68%. The average(${\pm}S.D.$) score of the MMSE-K for the patient group($27.23{\pm}2.62$) was significantly(p<0.001) lower than that of the healthy controls($29.20{\pm}1.24$). There were no statistically significant differences between four individual test scores of the 7MS of alcoholics with the MMSE-K score <24(N=3) and those of alcoholics with the MMSE-K score ${\geq}24$(N=28). 3) Four individual test scores of the 7MS seemed to have statistically significant association with such variables as MMSE-K, duration of alcohol drinking, blood magnesium concentration, liver function and thyroid function. Conclusion : Mild deficits of cognitive areas such as orientation, memory, visuospatial abilities and verbal fluency could be found in alcohol dependence.

• Journal of Nutrition and Health
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• 제35권3호
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• pp.303-313
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• 2002

1999년 7월 1일부터 1년간 아산재단 강릉병원에서 건강검진을 받은 성인 중에서 공복혈당장애군 (92명), 당뇨군 (119명) 및 이들과 성별 및 연령이 유사한 정상 대조군 (123명)을 대상으로 신체계측을 통하여 비만도를 평가하고, 혈압측정과 혈액분석 그리고 식품 섭취 빈도법을 이용하여 영양소 섭취량을 평가하였다. 1) 남자에서 공복혈당장애군의 BMI(25.7$\pm$2.7kg/$m^2$)와 비만도 지수(119.1$\pm$12.2%)는 당뇨군 및 정상군보다 유의하게 높았으며, WHR (0.92$\pm$0.04)과 혈압 (수축기 139$\pm$19.2mmHg, 이완기 85.1$\pm$12.2mmHg)은 당뇨군과는 차이를 보이지 않는 반면 정상군보다는 유의하게 높았다. 한편 여자의 경우, 공복혈당장애군의 체중, BMI, 비만도 지수 및 WHR는 당뇨군과는 유의한 차이를 보이지 않았으나, 정상군에 비해서는 유의하게 높았다. 2) 비만 이환율을 살펴보면, 남자의 경우 공복혈당장애군 (43.6%)-정상군 (27.4%)-당뇨군 (22.5%)의 순이었으나, 여자는 공복혈당장애군(76.7%)-당뇨군(63.3%)-정상군(54.0%)의 순으로 나타나, 공복혈당장애군에서 비만의 이환율이 더 높았으나 유의한 차이는 아니었다. 3) 남자에서 수축기 및 이완기 고혈압 위험 집단의 비율은 공복혈당장애군에서 각각 40.0%와 52.0%로 가장 높았으나 (p<0.05), 여자에서는 세 군 간에 유의한 차이를 보이지 않았다. 4) 남자에서 공복혈당장애군의 중성지방 농도(177.7$\pm$109.4mg/dl)와 AI(3.16$\pm$0.91)는 정상군 및 당뇨군과 유의한 차이를 보이지 않고 단지 두 군의 중간 정도의 범주에 해당되었다. 그러나, 여자에서는 공복혈당장애군의 AI, relative cholesterol의 수준이 정상군과는 유의하게 다르고, 오히려 당뇨군과는 유의한 차이를 보이지 않았다. 5) 영양소 섭취량은 정상군, 공복혈당장애군 및 당뇨군간에 유의한 차이를 보이지 않았다. 그러나 알코올로부터의 열량 섭취비율을 살펴보면, 남자의 경우 공복혈당장애군이 7.0$\pm$6.9%로서 정상군 (4.5$\pm$5.9%) 및 당뇨군 (5.6$\pm$6.1%) 보다 유의하게 높았다. 30~49세에 해당되는 중년 여성의 에너지, 단백질, 철분 섭취량을 권장량과 비교하여 보면, 각각 74.8$\pm$12.6%, 94.6$\pm$26.4% 및 64.5$\pm$14.1%로 당뇨군 (각각 112.8$\pm$28.5%, 157.8$\pm$68.2%, 92.8$\pm$21.7%)에 비해 유의하게 낮았고 정상군과는 유의한 차이를 보이지 않았다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.10027-10031
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• 2014

Background: We investigated the risk of cancer mortality according to obesity status and metabolic health status using sampled cohort data from the National Health Insurance system. Materials and Methods: Data on body mass index and fasting blood glucose in the sampled cohort database (n=363,881) were used to estimate risk of cancer mortality. Data were analyzed using a Cox proportional hazard model (Model 1 was adjusted for age, sex, systolic blood pressure, diastolic blood pressure, total cholesterol level and urinary protein; Model 2 was adjusted for Model 1 plus smoking status, alcohol intake and physical activity). Results: According to the obesity status, the mean hazard ratios were 0.82 [95% confidence interval (CI), 0.75-0.89] and 0.79 (95% CI, 0.72-0.85) for the overweight and obese groups, respectively, compared with the normal weight group. According to the metabolic health status, the mean hazard ratio was 1.26 (95% CI, 1.14-1.40) for the metabolically unhealthy group compared with the metabolically healthy group. The interaction between obesity status and metabolic health status on the risk of cancer mortality was not statistically significant (p=0.31). Conclusions: We found that the risk of cancer mortality decreased according to the obesity status and increased according to the metabolic health status. Given the rise in the rate of metabolic dysfunction, the mortality from cancer is also likely to rise. Treatment strategies targeting metabolic dysfunction may lead to reductions in the risk of death from cancer.