• Journal of Life Science
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• v.17 no.10
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• pp.1361-1367
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• 2007

I investigated the effect of KT5720, an inhibitor of protein kinase A, on the vesicular stomatitis virus (VSV) infection in BHK-21cell cultures. The virus inducted cytopathic effect (CPE) was almost completely suppressed by KT5720 at 5uM. The inhibitor, however, did not affect replication of the virus nor the synthesis of viral macromolecules. KT5720, did not block the cytoskeletal disruption, while the cell rounding was suppressed. And, the KT5720-sensitive function may be involved in developing the VSV-induced CPE, but not essential for the virus replications.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.2
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• pp.338-343
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• 2006

This paper describes about the design concept and the architecture of an economic VPN system which can perform fast crypto operations with cheap cost. The essence of the proposed system architecture is consisting of the system with two companion chips dedicated to VPN: one chip is a multi-purpose network processor for security machine and the other is a crypto acceleration chip which encrypt and decrypt network packets in a high speed. This study also addresses about some realizations that is required for fast prototyping such as the porting of an operating system, the establishment of compiler tool chain, the implementation of device drivers and the design of IPSec security engine. Especially, the second chip supports the most time consuming block cipher algorithms including 3DES, AES, and SEED and its performance was evaluated.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2018.05a
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• pp.129-130
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• 2018

In shipping logistics, despite the fact that it has promoted the information processing process, the use of the document exchange mechanism has caused a problem of increasing the cost and lead time. In recent years, various types of projects are in progress in preparation for full-scale introduction of a blockchain technology capable of solving the document exchange mechanism in the shipping industry, In near future, by expanding the practical application scope, it is aiming to increase competitiveness through transparency, reliability, stability, and efficiency, which are the effects of application of the block chain technology.

• The Korean Journal of Pain
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• v.18 no.1
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• pp.52-55
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• 2005

Complications following a well conducted epidural steroid injection are rare. A 50-year-old man developed a headache and neck stiffness 2 days after a lumbar epidural steroid injection. Under the impression of aseptic meningitis, fluid and nonsteroidal anti-inflammatory drug therapy was started immediately after cerebrospinal fluid (CSF) sampling. The CSF was turbid, and revealed a white blood cell count, protein, glucose and pressure of $550/{\mu}l$ (98% lymphocyte), 107.9 mg/dl, 48 mg/dl (serum 113 mg/dl) and $17cmH_2O$, respectively. The CSF stain and culture, and antibody test and polymerase chain reaction for pathogens were negative. A computed tomography (CT) scan of the brain revealed no abnormality, and a chest roentgenogram and the results of the neurological examination were normal. Under the impression of aseptic meningitis, the condition was managed conservatively, without antibiotics. Seven days later, the clinical symptoms had improved, and the patient discharged.

• Macromolecular Research
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• v.11 no.1
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• pp.2-8
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• 2003

The self-assembly of polymers can lead to supramolecular systems and is related to the their functions of material and life sciences. In this article, self-assembly of Langmuir-Blodgett (LB) films, polymer micelles, and polymeric nanoparticles, and their biomedical applications are described. LB surfaces with a well-ordered and layered structure adhered more cells including platelet, hepatocyte, and fibroblast than the cast surfaces with microphase-separated domains. Extensive morphologic changes were observed in LB surface-adhered cells compared to the cast films. Amphiphilic block copolymers, consisting of poly(${\gamma}$-benzyl L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) [or poly(N-isopropylacrylamide) (PNIPAAm)] as the hydrophilic one, can self-assemble in water to form nanoparticles presumed to be composed of the hydrophilic shell and hydrophobic core. The release characteristics of hydrophobic drugs from these polymeric nanoparticles were dependent on the drug loading contents and chain length of the hydrophobic part of the copolymers. Achiral hydrophobic merocyanine dyes (MDs) were self-assembled in copolymeric nanoparticles, which provided a chiral microenvironment as red-shifted aggregates, and the circular dichroism (CD) of MD was induced in the self-assembled copolymeric nanoparticles.

• Bulletin of the Korean Chemical Society
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• v.16 no.9
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• pp.873-885
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• 1995

The local structural and thermodynamical properties of blends A-B/H of a diblock copolymer A-B and a homopolymer H are studied using the polymer reference interaction site model (RISM) integral equation theory with the mean-spherical approximation closure. The random phase approximation (RPA)-like static scattering function is derived and the interaction parameter is obtained to investigate the phase transition behaviors in A-B/H blends effectively. The dependences of the microscopic interaction parameter and the macrophase-microphase separation on temperature, molecular weight, block composition and segment size ratio of the diblock copolymer, density, and concentration of the added homopolymer, are investigated numerically within the framework of Gaussian chain statistics. The numerical calculations of site-site interchain pair correlation functions are performed to see the local structures for the model blends. The calculated phase diagrams for A-B/H blends from the polymer RISM theory are compared with results by the RPA model and transmission electron microscopy (TEM). Our extended formal version shows the different feature from RPA in the microscopic phase separation behavior, but shows the consistency with TEM qualitatively. Scaling relationships of scattering peak, interaction parameter, and temperature at the microphase separation are obtained for the molecular weight of diblock copolymer. They are compared with the recent data by small-angle neutron scattering measurements.

• Journal of Korean Society for Quality Management
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• v.49 no.4
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• pp.527-537
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• 2021

Purpose: The purpose of this study was to suggest an improved version of Proof-of-Nonce (PoN) algorithm, which is a distributed consensus algorithm used for block chain system. Methods: First, we used response surface method for design of experiment that is to generate experimental points considering non-linear relationship among variables. Then, we employed overlapped contour plots for visualizing the impact of control variables to performance target. Results: First, we modified the consensus procedure of the existing PoN algorithm by diminishing the content of the exchanged message. Then, we verified the performance improvement of the new PoN algorithm by performing a numerical experiment and paired t-test. Finally, we established new regression models for consensus time and Transactions per second (TPS) and proposed a method for optimizing control variables for obtaining performance target. Conclusion: We could improve the performance of the previous version of PoN algorithm by modifying the content of the exchanged message during 4-steps of consensus procedure, which might be a stepping stone for designing an efficient and effective consensus algorithm for blockchain system with dynamic operation environment.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.121-128
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• 2021

After entering the 4th Industrial Revolution, the digital content market, which was only dependent on existing contents supply enterprises, is providing various digital content through the participation of users like YouTube. Accordingly, it activated the digital content market, but it causes a negative influence on the digital content market due to the copyright of the creator and the indiscriminate illegal use and usage of the content. This study researched digital content management technology based on blockchain technology to protect digital content and the copyright of the creator. The suggested technology protects the digital content and the copyright holder and discerns the users and prevents the indiscriminate approach and illegal use of digital content. For the safe management of digital content, hash function applied as the certification technology of blockchain is used to certify the users and manage the digital content and provide integrity and authentication service.

• Journal of KIBIM
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• v.11 no.3
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• pp.12-21
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• 2021

Existing real estate markets are monopolized because they are capital intensive and have information asymmetry. However, with the advent of the Fourth Industrial Revolution, technology is converging in various industries based on information technology (IT), and the real estate market is also developing a new field called "PropTech". According to this trend, new PropTech technologies are emerging in various real estate services sectors in Korea, but the electronic contract system, which accounts for the largest portion of the real estate industry, is still cited as a complex identification process and long processing time. Therefore, in this paper, we propose an improvement plan for the current electronic contract system through the introduction of blockchain technology, which is drawing attention with the development of PropTech, and explore the possibility of introduction by producing an experimental model of blockchain-applied electronic contract system in a programming language.

• Journal of Energy Engineering
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• v.27 no.4
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• pp.86-91
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• 2018

This paper is a review of accounts balancing time in small distributed power trading platform using blockchain technology. First, the national VPP energy management system using the AMI applied to this study is introduced and then the accounts balancing time and process of the cryptocurrency coin payment which based on the power generation of pro-consumer certified by power big data analysis in a test bed environment is discussed. Futhermore the configuration of a power Big Data analysis system with GPU Fast Big Data that applies MapD to current lambda architecture is also introduced.