• 한국자원식물학회지
• /
• 제22권1호
• /
• pp.96-101
• /
• 2009

독도는 460만 년 전부터 250만 년 전에 형성된 이래 울릉도나 본토와 한번도 맞닿은 적이 없었기 때문에 식물 진화를 논할 수 있는 식물지리학적으로 매우 중요한 의미 있는 섬이다. 동도의 광의의 귀화식물은 목본인 섬괴불나무와 보리밥나무 2종과 초본류 23종으로 총 27종류이다. 그리고 협의의 귀화식물은 방가지똥, 갓, 소리쟁이, 흰명아주, 그리고 개보리 등으로 5종류이다. 외부에서 이입된 귀화식물은 총 32종류에 해당하므로 동도 현존식물 약60종에 대해 60%에 해당한다. 따라서 독도는 이입종에 의한 생태적 교란이 매우 심하고 독도 고유 식물들의 생육환경이 매우 불안전한 상태이므로 자생종의 보전차원에서 귀화식물의 유입 차단이나 제거 등의 관리 방안이 도출되고 정책적인 관심이 요구된다고 판단된다.

• 한국광물학회지
• /
• 제18권3호
• /
• pp.205-214
• /
• 2005

울산단층 동쪽 지괴에 발달한 제4기 단층인 개곡1, 개곡2, 신계, 마동, 원원사, 진현단층을 대상으로 X선회절분석(XRD), 전자현미분석(EPMA), 후방산란전자영상분석(BSE), K-Ar연대측정법을 이용하여 단층비지의 광물조성과 미세조직의 특징을 연구하였다. 단층비지내 변질광물들은 단층운동에 수반된 열수변질작용으로 형성되었다. $28.9Ma\~44.3Ma$ 범위의 연대를 나타내는 단층비지는 주로 점토광물, 석영, 장석으로 구성된다. 점토광물은 스멕타이트가 주구성 광물이고 소량으로 녹니석, 일라이트 및 카올리나이트가 산출된다. 접촉부 모암과 단층 비지대에서는 단층작용과 관련된 열수작용에 의해 광물의 변질작용의 흔적이 쉽게 인지되고, 주입비지와 절단된 방해석맥 등과 같이 단층작용이 반복된 증거를 볼 때 단층비지대는 다중변형작용의 산물임을 알 수 있다. 녹색 내지 녹회색 계통인 진현단층의 비지의 경우 적색계통의 다른 단층비지에 비해 $Al_2O_3$의 함량이 높고, MgO와 CaO의 함량은 낮다. 스멕타이트의 화학분석 결과, 단층비지의 색은 기질을 구성하는 점토광물의 종류와 화학적 조성과도 밀접한 관계를 가진다.

• Restorative Dentistry and Endodontics
• /
• 제25권3호
• /
• pp.435-445
• /
• 2000

The purpose of this study was to compare the leakage of four different obturation techniques in conjunction with immediate apical barrier of ${\beta}$-tricalcium phosphate(TCP) in teeth with open apex. Eighty single-rooted human premolar teeth were prepared and sectioned horizontally, so maximum diameter in apex was 4mm. Apical defects that were similar to open apex, were created with #1/2 round bur and SF104R bur. The apical foramen were opened to a size 80 file extended 3mm beyond the apex. The teeth were placed into the oasis block soaked saline to simulate periapical tissue often associated with pulpless teeth and received apical barriers consisting of TCP followed by obturation using lateral condensation technique, vertical condensation technique, continuous wave technique and thermoplasticized gutta-percha injection technique. Two unobturated teeth served as positive and negative controls. Teeth were immersed in resorcinol-formaldehyde resin for S days at $4^{\circ}C$, and the resin was allowed to polymerize completely for 4 days at room temperature. Teeth were then sectioned horizontally at 1.5mm(level 1), 2.5mm(level 2) and 3.5mm(level 3) from the apex, and examined under a stereomicroscope at ${\times}40$ magnification. The photographs were taken at ${\times}40$ magnification of the filling in each level and scanned. The leakage length in tooth/resin interface was measured at each of the three levels. Each ratio of leakage was obtained by calculating the ratio of the leakage length of canal wall infiltrated with resin to the total length of the canal and was analyzed statistically(One-way ANOVA and Scheffe test). The result were as follows : 1. At the level 1, there was the least leakage in the thermoplasticized gutta-percha injection technique group(group 4), but there was statistically significant(p<0.05). 2. At the level 2, there was the least leakage in the thermoplasticized gutta-percha injection technique group(group 4), and the most leakage in the continuous wave technique group(group 3). There was statistically significant difference between the thermoplasticized gutta-percha injection technique group and the continuous wave technique group(p<0.05). 3. At the level 3, there was the least leakage in the thermoplasticized gutta-percha injection technique group(group 4), but there were no statistically significant differences between other groups(p>0.05). These results suggest that thermoplasticized gutta-percha injection technique which had 1mm apical gutta-percha matrix after the formation of TCP apical barrier, can demonstrate favorable apical sealing.

• Journal of Periodontal and Implant Science
• /
• 제38권1호
• /
• pp.51-58
• /
• 2008

Purpose: In dental clinical fields, various periodontal membranes are currently used for periodontal regeneration. The periodontal membranes are categorized into two basic types: resorbable and non-resorbable. According to the case, clinician select which membrane is used. Comparing different membranes that are generally used in clinic is meaningful. For this purpose, this study evaluates histological effects of various membranes in canine one wall intrabony defect models and it suggest a valuation basis about study model. Material and Method: The membranes were non-resorbable TefGen $Plus^{(R)}$, resorbable Gore Resolut $XT^{(R)}$ and resorbable $Osteoguide^{(R)}$. One wall intrabony defects were surgically created at the second and the mesial aspect of the fourth mandibular premolars in either right or left jaw quadrants in two dogs. The animals were euthanized 8 weeks post-surgery when block sections of the defect sites were collected and prepared for histological evaluation. Results: 1. While infiltration of inflammatory cells were observed in control, TefGen $Plus^{(R)}$ and Gore Resolut $XT^{(R)}$, it was not observed in $Osteoguide^{(R)}$. 2. TefGen $Plus^{(R)}$ had higher integrity than others and $Osteoguide^{(R)}$ was absorbed with folding shape. Gore Resolut $XT^{(R)}$ was divided everal parts during resorbtion and it was also absorbed from inside. 3. Quantity of new bone and new cementum was not abundant in all membranes. 4. For histologic evaluation of membranes we should consider infiltration of inflammatory, migration of junctional epithelium, integrity of membrane, quantity of new bone and new cementum, connective tissue formation and aspect of resorption. Conclusion: This histologic evaluation suggests that $Osteoguide^{(R)}$ provides periodontal regenerative environment with less inflammatory state. It is meangful that this study model suggests a valuation basis about other study model.

• 대한화학회지
• /
• 제18권2호
• /
• pp.97-109
• /
• 1974

sulfaguanidine 1수화물의 결정 및 분자구조를 X-선 회절법으로 규명하였다. 결정은 일사축계에 속하며 단위세포내에는 4분자가 있으며 공간군은 $P2_1$/c이다. 단위세포상수는 ${\alpha}=7.57{\pm}0.03,\;b=5.44{\pm}0.02,\;c=24.76{\pm}0.06{\AA},\;{\beta}=91.0{\pm}0.2^{\circ}$이다. 결정구조는 패터슨 함수의 해석과 직접법을 병용하여 밝혀냈다. 원자좌표치는 최소자승법으로 정밀화하였으며 1542개의 독립적인 회절반점에 대한 최종 R값은 0.14이었다. sulfaguanidine분자의 guanidyl기의 질소원자는 2개의 다른 물분자를 매개로 하여 수소결합을 하므로써 다른 분자들의 sulfonyl기의 산소원자에 연결되어 있다. 수소결합 형성에 있어서 물분자는 donor와 acceptor의 역할을 겸하고 있으며 수소결합은 사면체의 방향을 하고 있다. 2차원적인 수소결합에 의하여 연결된 분자들은 (001)면에 평행한 분자층을 형성하고 있다.

• 대한화학회지
• /
• 제5권1호
• /
• pp.33-37
• /
• 1961

We have shown that carboxy-peptidase destroys the biological activity of angiotensin octa-and deca-peptides. Since Proline occurs as the seventh amino acid from the amino end of the chain and since carboxypeptidase does not cleave proline from a peptid chain, it is evident that the heptapeptid H.asp-arg-val-tyr-ileu-his-pro.OH is formed by this hydrolysis. This peptide must then be biologically inactive. In order to determine whether the phenyl group of the C-terminal amino acid was the necessary requirement for biological activity of the octapeptide, $ala^8$ angiotensin octapeptide(amino acids of peptides numbered from amino end) was synthesized. For this synthesis the four dipeptides were prepared: carbobenzoxy-L-prolyl-L-alanine-P-nitrobenzyl-ester, m.p. $134-135^{\circ}C,$ carbobenzoxy-L-isoleucyl-imidazole benzyl-L-histidine methyl ester, m.p. $114-116^{\circ}C,$ carbobenzoxy-L-valyl-L-tyrosine hydrazide and carbobenzoxy B-benzyl-L-aspartyl-nitro-L-arginine. The first three dipeptides were obtained as crystalline compounds. Imidazole-benzyl-L-histidine was used in the hope that it would block the histidine imidazole against side reactions in steps subsequent to the formation of the C-terminal tetrapeptide. Also, it was through that the imidazole benzylated peptides would be easier to crystallize. This, however, was not the case. The tetrapeptide, carbobenzoxy-L-isoleucyl-L-im, benzyl-histidyl, L-prolyl-L-alanine-nitrobenzyl ester was not obtained in a crystalline form. Neither could the mono-or dihydrobromide of the tetrapeptide free base be induced to crystallize. Carbobenzoxy-L-valyl-L-tyrosine azide was condensed with the tetrapeptide free base to yield the protected hexapeptide; carbobenzoxy-L-valyl-L-tyrosyl-L-isoleucyl-L-im, benzyl, histidyl-L-Prolyl-L-alanine-nitrobenzyl ester. Upon removal of the carbobenzoxy group with hydrogen bromide in acetic acid an amorphous free base hexapeptide ester was obtained. This compound gave the correct C, H, N analysis and contained the six amino acids in the correct ratio. The octapeptide was obtained by condensing this hexapeptide with carbobenzoxy-B-benzyl-L-aspartyl-nitro, L-arginine using the mixed anhydride method of condensation. This amorphous product was proven to be homogenous by chromatography in two solvent systems and upon hydrolysis yielded the eight amino acids in correct ratio. The five protecting groups were removed from the octapeptide by hydrogenolysis over palladium black catalyst. Biological assay of the free peptide indicated that it possessed less than 0.1 per cent of both pressor and oxytocic activity of the phenylalanine8 angiotensin. This suggests that the phenyl group is a point of attachment between angiotensin and its biological receptor site.

• Restorative Dentistry and Endodontics
• /
• 제25권1호
• /
• pp.1-16
• /
• 2000

It is difficult to treat the endodontic apical perforation successfully. In this study, we hypothesized that the application of PDGF-BB and IGF-I into periapical perforation site may accelerate periapical healing and lead to bone deposition. And the specificity of osteonectin in periapical healing was investigated. The experiments were performed on the upper and lower 51 premolar teeth of 4 beagle dogs. The pulp chamber of each tooth was opened and the dental plaque was inserted into the canal for developing the periapical lesion for 5 weeks. Then, the roots were artificially perforated at the apex with the number 4 profile of .06 taper. In each step, standard periapical radiographs were taken to compare the size of lesion each other. The radiographs were scanned and analyzed by image analysis system. The mean and standard deviation of periradicular radiolucency ratios were calculated in each group. ANOVA was used for comparison. 51 premolars were grouped into 3 groups; control group, calcium hydroxide-treated group and calcium hydroxide plus growth factors-treated group. In the control group, the apical perforations were not sealed and obturated with gutta-percha and ZOE sealer by lateral condensation technique. In the experimental groups, the apical perforation were sealed with calcium hydroxide and with/without $4{\mu}g$ of PDGF-BB & IGF-I in cellulose gel and obturated by lateral condensation technique. Fluorescent bone markers were used to measure new bone formation. Following 2, 4, 12 weeks after experiment the dogs were sacrificed and histologic sections were prepared. Each tooth block including periapical lesion was sectioned mesiodistally. One half of the sections were decalcified with 6% nitric acid and processed by standard paraffin embedding technique. The sections were stained by hematoxylin and eosin, and immunostained for osteonectin. Histomorphometrical measurement of neoformed bone was performed using a light microscope. And the other half of the sections were prepared by undecalcified preparation, and confocal laser scanning microscopic investigations were done.

• 디지털융복합연구
• /
• 제17권6호
• /
• pp.219-227
• /
• 2019

본 연구는 계량정보학 네트워크 분석을 중심으로 블록체인 분야의 한국 연구자의 학술연구 동향을 계량학적 시각으로 살펴보고자 하였다. 데이터는 2009년부터 2018년까지 KCI와 NTIS, WoS 및 Scopus에 등재된 블록체인 논문으로 선정하였다. 계량정보학 연구방법으로 논문 발행, 연구의 분야, 공저자, 단어분석을 수행했다. 분석결과, 2017년부터 논문 수가 급증하였으며 공저자 네트워크 형성의 초기단계를 보였다. 논문제목에 많이 사용된 단어는 응용발전과 쟁점 및 기술개발과 관련된 단어들이 주로 나타났다. 또한 국내논문연구 분야는 사회과학 주제가 가장 많은 반면에 국제논문연구는 공학 주제가 가장 많았다. 시기별 분석결과는 한국학자들의 블록체인 3.0 연구는 2017년 시작되었고 2018년 빠르게 늘고 있다. 논문 피인용 수는 발행연도와 관련이 있었지만, 공저자 수와는 무관하였다. 이러한 계량정보학적 동향을 살펴봄으로써 블록체인 분야의 발전에 유용한 기초자료가 될 수 있을 것으로 기대한다. 향후연구는 블록체인 분야의 세계범위 지적 구조와 특징이 더욱 명확하게 드러날 것으로 기대한다.

• Nuclear Engineering and Technology
• /
• 제53권1호
• /
• pp.61-68
• /
• 2021

Experiments of vertically upward steam-water two-phase flow have been carried out in single-side heated narrow rectangular channel with a gap of 3 mm. Flow patterns were identified and classified through visualization directly. Slug flow was only observed at 0.2 MPa but replaced by block-bubble flow at 1.0 MPa. Flow pattern maps at the pressure of 0.2 MPa and 1.0 MPa were plotted and the difference was analyzed. The experimental data has been compared with other flow pattern maps and transition criteria. The results show reasonable agreement with Hosler's, while a wide discrepancy is observed when compared with air-water two-phase experimental data. Current criteria developed based on air-water experiments poorly predict bubble-slug flow transition due to the different formation and growth of bubbles. This work is significant for researches on heat transfer, bubble dynamics and flow instability.

• 자원환경지질
• /
• 제37권4호
• /
• pp.413-424
• /
• 2004

한반도의 북중국/남중국지괴와의 연계성 및 충돌의 영향을 근거로 한반도의 지체구조적 진화를 알아보기 위하여 경기육괴에 분포하는 중생대 대동누층군과 원생대 변성암인 서산층군에 대하여 고지자기 연구를 수행하였다. 대동누층군에 대해서는 26개 지점 239개의 시료 중 14개 지점 106개의 시료에서 생성당시의 특성잔류자화 방향을 추출하였다. 특성잔류자화 방향은 경사보정 후 평균방향이 D/I=74.5$^{\circ}$/36.7$^{\circ}$(k=60.7, $\alpha$=5.1$^{\circ}$)이며 이는 경사보정 전의 방향 D/I=61.9$^{\circ}$/52.8$^{\circ}$(k=4.4, $$\alpha$_{95}$=21.5$^{\circ}$)보다 집중된 분포를 나타내므로 암석생성당시 획득된 일차자화임을 지시한다. 경사보정 후의 방향으로부터 계산한 고지자기극은 208.0$^{\circ}$E, 24.5$^{\circ}$N (n=14, K=67.5,$A_{95}$=4.9$^{\circ}$)에 위치하며 중기 트라이아스기 남중국지괴의 고자기극과 통계학적으로 유사하므로 이 기간 동안 대동누층군은 남중국지괴와 지구조적으로 동일했던 것으로 해석되며 남중국지괴와 한반도의 충돌에 따른 변형$.$변성작용에도 일차자화가 보존되었음을 지시한다. 서산층군의 33개 지점에서 채취한 279개 시료의 대부분은 분산된 방향을 나타내며, 오직 쥬라기 화강암 주변의 6개 지점에서 채취한 36개의 시료로부터 특성잔류자화 방향을 추출하였다. 이와 같은 결과는 경기육괴의 최대 변성시기인 북중국/남중국지괴와의 충돌과 연관된 고생대 말기에서 중생대 쥬라기 시기의 지구조 운동의 영향으로 추측된다. 지층경사보정 이전의 잔류자화 방향은 D/I=45.7$^{\circ}$/60.1$^{\circ}$(k=41.2, $$\alpha$_{95}$=10.6$^{\circ}$)이며 이로부터 구해진 고지자기극의 위치는 195.0$^{\circ}$E, 51.6$^{\circ}$N(n=6, K=20.8,$A_{95}$=12.4$^{\circ}$)로서 한반도 쥬라기 또는 백악기 초의 고지자기극과 유사하다. 그러나 서산층군의 특성잔류자화 방향은 조산운동의 직접적인 영향보다는 조산운동 후기 또는 이후에 쥬라기 대보화강암의 정치와 연관되어 획득된 재자화 방향으로 해석하였다.