• Journal of Korean society of Dental Hygiene
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• v.18 no.1
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• pp.19-29
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• 2018

Objectives: Despite a rise of an interest in tooth whitening, diverse problems are being caused in case of hydrogen peroxide that is being used as a tooth bleaching agent. Thus, the aim was to examine tooth whitening effectiveness using natural products as a plan for supplementing this. Methods: As a result of having measured a tooth color through using VITA Easyshade V after having developed toothpaste with the application of extracts such as Citrus Peels, Mulberry (Morus alba L.) Root Bark, strawberry, and lemon, and then having used it for 10 weeks, they are as follows. Both upper and lower 6 anteriors mostly got brighter. Results: A statistically significant difference was shown especially in the right canine (p=0.015), in the right central incisor (p=0.007), and in the left central incisor (p<0.001). In consequence of having measured a color change, the tooth got brighter gradually in the higher extract content and in the lengthier use time. In case of canine, it got less bright compared to other teeth. In the outcome of evaluating sensuality, most of the questions were indicated to be high in case of using a whitening toothpaste for 10 weeks. But in what "there is no stickiness in the mouth, the stickiness was more felt in the use up to 5 weeks, but was improved in 10 weeks. Conclusions: The bleaching effectiveness was proved by developing a toothpaste with the application of natural extracts. A short-term effect cannot be seen like a whitening agent of using hydrogen peroxide. But there is a continuous effect in consideration of tooth-brushing more than 3 times a day.

• Proceedings of the KACD Conference
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• 2003.11a
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• pp.573-573
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• 2003

I. Objective This study evaluated the microshear bond strength of teeth bleached with commercial whitening strips and compared with those bleached with home bleaching gel. II. Materials and Methods Twelve exrtacted central incisors were cut into pieces and central four segments were chosen from each tooth and embedded in acrylic resin. Four blocks with 12 tooth segments embedded in acrylic resin were acquired and numbered from one to four. Block 1 was bleached with Crest Whitestrips, block 2 with Claren, block 3 with Opalescence tooth whitening gel(10% carbamide peroxide).(omitted)

• Restorative Dentistry and Endodontics
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• v.34 no.2
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• pp.95-102
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• 2009

The aim of this study was to evaluate the influence of light energy on the tooth whitening effect of bleaching agent in vitro..Extracted human mandibular molars were sectioned to 2 fragments(mesial. distal) and lingual portions of crown were used in this study. All specimens were stained using a red wine for 24 hours and immersed in artificial saliva. Specimens divided into four groups, group 1 and 2 light-activated by LumaCool (LED, LumaLite, Inc., Spring Valley, USA), group 3 and 4 light-activated by FlipoWhite2 (Plasma acr lamp, Lokki. Australia). Group 1 and 3 bleached with Luma White (LumaLite, Inc., Spring Valley, USA), group 2 and 4 bleached with Polaoffice(SDI, Victoria, Australia). Bleaching treatment performed during 10 minutes every 24 hours and repeated 6 times. During bleaching treatment, distal fragments was light-activated (L) but mesial fragments was not(NL). Shade assessment employed before and after bleaching treatment using spectrophotometer. The results of the change in shade was compared and analysed between NL and L by using paired-sample T test with 95 % level of confidence. There were no significant differences between NL and L with a few exceptions. In group 2, $a^*$ value more change in L, in group 3, $b^*$ value more change in L, in group 4, $a^*$ value less change in L. After bleaching, $L^*$ value and ${\Delta}E$ increased in all groups and the value of $a^*$ and $b^*$ decreased in all groups. Within the limitation of this test conditions, the results of this study indicate that the light energy has no obvious improving impact on the tooth whitening effect of a bleaching agent.

• Journal of dental hygiene science
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• v.13 no.1
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• pp.13-19
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• 2013

This study evaluated the change of color and the microhardness according to time-out using the office bleaching with in vitro test after bleaching one time 1 day per week, total three times, for the control group and three times per 1day for the experimental group. $L^*$ was increased in both groups. Group 1 showed a significant increase statistically between before and after tooth whitening (p<0.05). Group 2 showed a significant increase statistically between before and after tooth whitening (p<0.05). ${\Delta}E^*$ was huge in both groups. In group 1, it was great in terms of statistical significance between 1 day and 7 days after tooth whitening (p<0.05). In group 2, it was the greatest between before and 1 day after tooth whitening and was significant statistically as well (p<0.05). Vickers hardness number (VHN) decreased in both groups. In group 1, VHN decreased over time and the difference was significant statistically (p<0.05). In group 2, VHN decreased over time and the difference was significant statistically (p<0.05). Percentage microhardness loss was great in both groups. In group 1, it was the greatest between 1 day and 7 days after the treatment, and it was significant statistically (p<0.05). In group 2, it was the greatest between before and 1 day after the treatment, and it was significant statistically (p<0.05). Put together, the more frequent tooth whitening a day is, the longer the period of tooth whitening when applying the same frequency, the greater color change was, however the microhardness decreased, in regard to the results over time using 15% hydrogen peroxide tooth whitening product for professionals.

• Journal of dental hygiene science
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• v.22 no.3
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• pp.156-163
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• 2022

Background: This study attempted to apply resin infiltrant (RI) as a method to maintain the effect of tooth bleaching treatment and compared it with fluoride varnish (FV) or artificial saliva to evaluate the effect. Methods: Sixty healthy lozenge specimens were classified into five groups. Group 1 was the negative control group, and discoloration was induced after artificial saliva treatment of the tooth specimen (G1_S+C). Group 2 was a positive control group, in which pigmentation was induced after bleaching treatment and artificial saliva treatment (G2 _B+S+C). Coloration was induced in group 3 (experimental group 1) after bleaching treatment and artificial saliva treatment, followed by application of fluorine varnish (G3_B+FV+S+C). Coloration was induced in Group 4 (experimental group 2) after applying RI after bleaching treatment and artificial saliva treatment (G4_B+RI+S+C). Pigmentation was induced in group 5 (experimental group 3) after bleaching treatment and artificial saliva treatment, followed by acid treatment (etching) and treatment with RI (G5_B+E+RI+S+C). Coffee and wine were used to induce discoloration. The lightness value (L^*) of the CIE L^*a^*b^* color system was obtained by image analysis. Kruskal-Wallis H analysis was performed for the mean difference in L^* values by group. Results: When coloration was induced with coffee, there was no significant difference in L^* value between artificial saliva (G2 _B+S+C), FV (G3_B+FV+S+C), and RI (G4_B+RI+S+C, G5_B+E+RI+S+C) groups. There was no significant difference in L^* values between the artificial saliva (G2 _B+S+C), FV (G3_B+FV+S+C), and RI (G4_B+RI+S+C, G5_B+E+RI+S+C) groups, even in the case of wine induced coloration. Conclusion: It was confirmed that artificial saliva or RI treatment had similar effects to the FV previously used to maintain the effect of tooth bleaching treatment.

• Journal of dental hygiene science
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• v.21 no.3
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• pp.178-184
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• 2021

Background: As the importance of the esthetic function of teeth increases, the use of esthetic restoration materials and whitening treatment are increasing. The purpose of this study was to investigate the color change of esthetic restoration materials upon using staining and whitening toothpaste. Methods: Light curing (LC) packable composite resin, LC flowable resin, LC glass ionomer (GI), and self-curing GI specimens were colored in coffee or curry for three hours a day for seven days. After that, regular toothpaste, whitening toothpaste containing hydrogen peroxide, and whitening toothpaste containing activated charcoal were applied for three minutes three times a day for two weeks. Luminosity (L), chromaticity a (a), and chromaticity b (b) were measured using a spectrophotometer once a week. Results: In the coffee-colored group, the change in L^2*a^2*b² (E²) with time was significant (p=0.004), there was no difference for different toothpaste types (p=0.646), and there was significant difference (p<0.001) for different esthetic restorative materials. The change of E² in the curry-colored group was significant only for different esthetic restorative materials (p<0.001). In the coffee-colored group, the L, a, and b values of the light-curing GI showed greater change than other materials after staining and one week after whitening, turning dark, red, and yellow. In the curry-colored group, L did not differ for different materials and times, and a and b showed the greatest difference in light-curing GI after staining and one and two weeks after whitening. Conclusion: The use of whitening toothpaste for two weeks was not different from the use of general toothpaste in the removal of staining or whitening. Since light-curing GI is the most vulnerable to coloration, it is recommended that coloring by food chromogen should be explained in advance, before using light-curing GI for teeth restoration.

• Restorative Dentistry and Endodontics
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• v.36 no.4
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• pp.306-312
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• 2011

Objectives: This clinical study evaluated the effect of light activation on the whitening efficacy and safety of in-office bleaching system containing 15% hydrogen peroxide gel. Materials and Methods: Thirty-three volunteers were randomly treated with (n = 17, experimental group) or without light activation (n = 16, control group), using Zoom2 white gel (15% $H_2O_2$, Discus Dental) for a total treatment time of 45 min. Visual and instrumental color measurements were obtained using Vitapan Classical shade guide and Shadepilot (DeguDent) at screening test, after bleaching, and 1 month and 3 month after bleaching. Data were analyzed using t-test, repeated measure ANOVA, and chi-squared test. Results: Zoom2 white gel produced significant shade changes in both experimental and control group when pre-treatment shade was compared with that after bleaching. However, shade difference between two groups was not statistically significant (p > 0.05). Tooth shade relapse was not detected at 3 months after bleaching. The incidence of transient tooth sensitivity was 39.4%, with being no differences between two groups. Conclusions: The application of light activation with Zoom2 white gel system neither achieved additional whitening effects nor showed more detrimental influences.

• Journal of dental hygiene science
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• v.23 no.4
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• pp.351-360
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• 2023

Background: The purpose of this study is to investigate the tooth whitening effect of Listerine Healthy White and provide effective management of extrinsic discoloration by comparing the whitening effects of existing whitening products. Methods: The included study four groups: those using whitening gel, whitening toothpaste, and Listerine Healthy White and a control using artificial saliva. Each group received 40 bovine tooth specimens, which were stained with commonly consumed tooth-coloring-inducing foods; black tea, black coffee, and instant noodles for 72 hours. The specimens were treated with tooth whitening materials for 5 weeks, after which the lightness (L^*) was measured weekly using a spectrophotometer. Results: There was a significant difference in lightness among the groups between the 1st and 5th week of treatment for all tooth-coloring-inducing foods (p<0.05). When comparing the changes in lightness values from before whitening to the 5th week of whitening for all tooth-coloring-inducing foods, the order of change was as follows: whitening gel, whitening toothpaste, Listerine Healthy White, and artificial saliva. Listerine Healthy White showed a significant whitening effect for all tooth-coloring-inducing foods (p<0.05). Particularly, changes in lightness values for specimens stained by black tea after 5 weeks of whitening were in the following order: whitening gel (21.72), whitening toothpaste (14.89), Listerine Healthy White (12.91), and artificial saliva (3.85). For specimens stained by black coffee, the changes in lightness values were in the following order: whitening gel (12.99), whitening toothpaste (9.66), Listerine Healthy White (7.91), and artificial saliva (3.12). Lastly, changes in lightness values for specimens stained by instant noodles were as follows: whitening gel (10.84), whitening toothpaste (9.85), Listerine Healthy White (7.71), and artificial saliva (2.61). Conclusion: Listerine Healthy White exhibits continuous whitening effects over time, and for consumers seeking convenient ways to achieve tooth whitening effects at home, consistent use of Listerine Healthy White is recommended.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2007.11a
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• pp.129-139
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• 2007

Many modalities of treatment for acquired skin hyperpigmentation are available including chemical agents or physical therapies, but none are completely satisfactory. The ideal depigmenting compound should have a potent. rapid and selective bleaching effect on hyperactivated melanocytes, carry no short- or long-term side-effects and lead to a permanent removal of undesired pigment. acting at one or more steps of the pigmentation process. Depigmentation can be achieved by regulating (i) the transcription and activity of tyrosinase, tyrosinase related protein-1 (TRP-1), tyrosinase related protein-2 (TRP-2), and/or peroxidase; (ii) the uptake and distribution of melanosomes in recipient keratinocytes and (iii) melanin and melanosome degradation and turnover of pigmented keratinocytes. One of the interesting point for development of skin whitening agent is Mitf(Microphthalmia-associated transcription factor). Mitf belongs to the basic helix-loop-helix-zip family of trabscription factors and it is crucial as it regulates both melanocyte proliferation as well as melanogenesis and is the major regulator of tyrosinase and the related enzymes (TRPs), as well as many melanosome structural proteins such as pMel17. Recently, we developed MITF-down-regulating agents from natural and synthetic sources, which have anti-melanogenic effect on in vitro and in vivo. We suggested that potent MITF-down regulating agents might be used for skin whitening cosmeceuticals.

• Restorative Dentistry and Endodontics
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• v.31 no.4
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• pp.269-281
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• 2006

This study evaluated the effectiveness and safety of an experimental bleaching strip (Medison dental whitening strip. Samsung medical Co., Anyang, Korea) containing 2.9% hydrogen peroxide. Twenty-three volunteers used the bleaching strips for one and a half hour daily for 2 weeks. As control group. the same strips in which hydrogen peroxide was not included were used by 24 volunteers with the same protocol. The shade change (${\Delta}E^{*}$, color difference) of twelve anterior teeth was measured using Shade Vision (X-Rite Inc., S.W. Grandville, MI, USA). Chroma Meter (Minolta Co., Ltd. Osaka. Japan) and Vitapan classical shade guide (Vita Zahnfabrik, Germany). The shade change of overall teeth in the experimental group was significantly greater than that in the control group (p < 0.05) and was easily perceivable. The change resulted from the increase of lightness (CIE $L^{*}$ value) and the decrease of redness (CIE $a^{*}$ value) and yellowness (CIE $b^{*}$ value). The shade change of individual tooth was greatest in canine. and smallest in central incisor. The safety of the bleaching strip was also confirmed.