• Title/Summary/Keyword: Bioscience

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ASSESSMENT OF STABILITY AND ALLERGENICITY OF FOOD ALLERGENIC PROTEINS

  • Lee, J-H;Yoon, W-K;Han, S-B;Yun, S-O;Park, S-H;Lee, H-J;Yoon, P-S;Moon, J-S;Kim, H-C
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.180-180
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    • 2002

  • The potential allergenicity of the transgene products in genetically modified organisms (GMOs), has been an important issue. As a part of the risk assessment of GMOs, we investigated the physicochemical stability and the immunogenicity of food allergens to determine their allergenicity.(omitted)

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Activation of toll-like receptor signaling by polysaccharide isolated from cell culture of Acantopanax senticosus

  • Ahn, H-J;Han, S-B;Yoon, Y-D;Lee, H-S;Moon, J-S;Lee, C-W;Lee, K-H;Park, S-K;Kim, H-C
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.182-182
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    • 2002

  • We investigated the mechanism of immunomodulatory action of polysaccharide isolated from cell culture of Acanthopanax senticosus (ASP). ASP was found to increase directly proliferation and differentiation of B cells, and cytokine production of macrophages, but not proliferation and cytokine production of T cells.(omitted)

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Immunomodulatory activity of a polysaccharide isolated from cell culture of Acantopanax senticosus

  • Ahn, Hyo-Jung;Han, Sang-Bae;Yoon, Yeo-Dae;Lee, Haeng-Soon;Moon, Jae-Sun;Lee, Chang-Woo;Lee, Ki-Hoon;Park, Song-Kyu;Kim, Hyung-Chin;Kim, Hwan-Mook
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.259.1-259.1
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    • 2002

  • Many polysaccharides isolated from plants are considered to be biological response modifiers and have been shown to enhance various immune responses in vivo and in vitro. Here we demonstrate that a polysaccharide isolated from cell culture of Acanthopanax senticosus (AS) has a unique mode of immunostimulation with regard to its cell-type specificity. AS was found to markedly increase polyclonal IgM antibody production and the proliferation of B cells. and to activate iNOS transcription and NO production in macrophages. (omitted)

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