• 대한의생명과학회지
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• 제17권2호
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• pp.95-104
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• 2011

The development of a general appreciation for the central role of angiogenesis in cancer growth and metastasis and other disease status has led to a wide range of new therapeutic strategies. This paper reviews the domestic and international trends through technology, marketing and patent information analysis dealing with anti-angiogenic agents. This analytical research has led to the identification of new targets associated with angiogenesis, leading to the development of an extensive number of preclinical screening of antiangiogenetic agents.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 춘계학술발표대회
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• pp.289-292
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• 2010

Recently human activity recognition using accelerometer has become a prominent research area in proactive computing. In this paper, we present a real-time activity recognition system using a single tri-axial accelerometer. Our system recognizes four primary daily human activities: namely walking, going upstairs, going downstairs, and sitting. The system also computes extra information from the recognized activities such as number of steps, energy expenditure, activity duration, etc. Finally, all generated information is stored in a database as daily log.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 학술대회 논문집 정보 및 제어부문
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• pp.472-473
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• 2008

심실조기수축(PVC: Premature Ventricular Contraction)은 성인에게서 가장 흔하게 발생되는 심장 부정맥 증상 중의 하나이다. 심실조기수축 부정맥이 자주 발현되는 사람의 경우 관상 동맥질환, 고혈압 등의 심혈관계 질환이 진행되고 있을 가능성이 많고, 심실빈맥이나 심실세동으로 전이되는 경우 심정지 등을 유발하여 사망에 이르기 때문에 지속적으로 관찰이 필요한 증상이다. 따라서 본 연구에서는 R-R 간격 정보를 이용하여 심실조기수축 부정맥 증상을 실시간으로 검출할 수 있는 신호처리 알고리즘을 구현하고자 하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 D
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• pp.2157-2158
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• 2006

Heart Rate Variability (HRV) system is useful for evaluating the balance in homeostasis of autonomic nervous system. In this study, we implement HRV monitoring system by performing real time FFT spectrum analysis on R-R intervals data acquired from Electrocardiogram (ECG) acquisition and transmitting the data by RF communication module.

• Genomics & Informatics
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• 제3권1호
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• pp.39-42
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• 2005

DNA microarray is a high-throughput biomedical technology that monitors gene expression for thousands of genes in parallel. The abundance and complexity of the gene expression data have given rise to a requirement for their systematic management and analysis to support many laboratories performing microarray research. On these demands, we developed Xperanto for integrated data management and analysis using user-friendly web-based interface. Xperanto provides an integrated environment for management and analysis by linking the computational tools and rich sources of biological annotation. With the growing needs of data sharing, it is designed to be compliant to MGED (Microarray Gene Expression Data) standards for microarray data annotation and exchange. Xperanto enables a fast and efficient management of vast amounts of data, and serves as a communication channel among multiple researchers within an emerging interdisciplinary field.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.81-81
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• 2003

This event-related fMRI study was to further our understanding about how different brain regions could contribute to effective access of specific information related to cognitive process and shows the different response of brain regions involved in recognition of familiar faces compared to unfamiliar faces and repetition effect.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.142-145
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• 1997

This paper presents the development of depth extraction algorithm or the 3D Endoscopic Data using a stereo matching method and depth calculation. The purpose of other's algorithms is to reconstruct 3D object surface and make depth map, but a one of this paper is to measure exact depth information on the base of [cm] from camera to object. For this, we carried out camera calibration.

• 대한의생명과학회지
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• 제28권4호
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• pp.307-311
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• 2022

The extract of EA lacks studies showing its efficacy other than that it contains caffeic acid, an active compound that has antioxidant and neuroprotective effects on nerve cells. Therefore, in this study, we attempted to determine the effectiveness of EA extraction. In this study, we performed a DPPH assay to determine the antioxidant potential of EA. And then, the cytotoxic concentration of EA in HaCaT keratinocytes was determined, and the antioxidant effect was determined by measuring the malondialdehyde (MDA). The results of DPPH, a chemical antioxidant assay, clearly demonstrated the antioxidant capacity of EA extracted with distilled water. In addition, cell-based assays provide useful information on the protective effect of EA on oxidative stress-induced apoptosis.

• 대한의용생체공학회:의공학회지
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• 제28권1호
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• pp.84-94
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• 2007

In order to collect information on local distribution of conductivity and permittivity underneath a scan probe, we developed a multi-frequency trans-admittance scanner (TAS). Applying a sinusoidal voltage with variable frequency on a chosen distal part of a human body, we measure exit currents from 320 grounded electrodes placed on a chosen surface of the subject. The electrodes are packaged inside a small and light scan probe. The system includes one voltage source and 17 digital ammeters. Front-end of each ammeter is a current-to-voltage converter with virtual grounding of a chosen electrode. The rest of the ammeter is a voltmeter performing digital phase-sensitive demodulation. Using resistor loads, we calibrate the system including the scan probe to compensate frequency-dependent variability of current measurements and also inter-channel variability among multiple. We found that SNR of each ammeter is about 85dB and the minimal measurable current is 5nA. Using saline phantoms with objects made from TX-151, we verified the performance of the lesion estimation algorithm. The error rate of the depth estimation was about 19.7%. For the size estimate, the error rate was about 15.3%. The results suggest improvement in lesion estimation algorithm based on multi-frequency trans-admittance data.

• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.647-656
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• 2007

The purpose of this study was to analyze the effects of vibratory stimulus as somatosensory inputs on the postural control in human standing. To study these effects, the center of pressure(COP) was observed while subjects were standing on a stable and an unstable support with co-stimulated mechanical vibrations to flexor ankle muscles(tibialis anterior tendon, achilles tendon) and two plantar zones on both foot. The COP sway measurement was repeated twice in four conditions: (1) with visual cue and vibration, (2) without visual cue and vibration, (3) with visual cue and without vibration, (4) without visual cue and with vibration. The calculated parameters were the COP sway area and the distance, the median frequency and the spectral energy of COP sway in three intervals $0.1{\sim}0.3,\;0.3{\sim}1,\;1{\sim}3Hz$. The results showed that vibratory stimulus affect postural stability. The reduction rate of the COP sway with vibratory stimulus were higher on the unstable support because the effect of postural stability increases when afferent nervous flow is more activated by vibration on unstable support. If unclear visual or vibratory information is received, one type of information is compared with the other type of sensory information. Then the input balance between visual and vibratory information is corrected to maintain postural stability. These findings are important for the rehabilitation system of postural balance control and the use of vibratory information.