• Genomics & Informatics
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• 제16권3호
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• pp.75-77
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• 2018

Genomics & Informatics (NLM title abbreviation: Genomics Inform) is the official journal of the Korea Genome Organization. Text corpus for this journal annotated with various levels of linguistic information would be a valuable resource as the process of information extraction requires syntactic, semantic, and higher levels of natural language processing. In this study, we publish our new corpus called GNI Corpus version 1.0, extracted and annotated from full texts of Genomics & Informatics, with NLTK (Natural Language ToolKit)-based text mining script. The preliminary version of the corpus could be used as a training and testing set of a system that serves a variety of functions for future biomedical text mining.

• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.703-712
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• 2007

In this paper, we designed the RFID(Radio Frequency Identification) Emergency Medical Information System(REMIS). This REMIS offers the emergency patient's medical information using RFID and HL7(Health Level 7) to an emergency medical technician. In emergency situation as like coma, if the communication, from the patient's current location to the hospital, is possible, REMIS offer the medical information of the patient through REMIS server to an emergency medical technician. In the state of communication blocked, REMIS can offer the patient identification and the emergency information through RFID tag, which the patient wear, to an emergency medical technician. When this system was designed, the protection of the patient's medical information and their privacy was considered, and the HL7 was used to be compatible with another medical systems. Therefore, in this paper, REMIS was designed that it is always possible to offer the emergency patient's information to an emergency medical technician regardless of any communication status and to improve the emergency rescue process, effectively.

• 대한의용생체공학회:의공학회지
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• 제27권6호
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• pp.392-401
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• 2006

Image Guided Surgery (IGS) system which has variously tried in medical engineering fields is able to give a surgeon objective information of operation process like decision making and surgical planning. This information is displayed through 3D images which are acquired from image modalities like CT and MRI for pre-operation. The technique of image registration is necessary to construct IGS system. Image registration means that 3D model and the object operated by a surgeon are matched on the common frame. Major techniques of registration in IGS system have been used by recognizing fiducial markers placed on the object. However, this method has been criticized due to additional trauma, its invasive protocol inserting fiducial markers in patient's bone and generating noise data when 2D slice images are acquired by image modality because many markers are made of metal. Therefore, this paper developed shape-based registration technique to improve the limitation of fiducial marker based IGS system. Iterative Closest Points (ICP) algorithm was used to match corresponding points and quaternion based rotation and translation transformation using closed form solution applied to find the optimized cost function of transformation. we assumed that this algorithm were used in Total Knee replacement (TKR) operation. Accordingly, we have developed region-based 3D registration technique based on anatomical landmarks and this registration algorithm was evaluated in a femur model. It was found that region-based algorithm can improve the accuracy in 3D registration.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.104-105
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• 1998

To minimize the Y2K (year 2000) date aware problem of medical devices, we are developing a database that keeps the data such as equipment type, specification, serial number, model number, acquisition date, vendor, manufacturer of the device as well as the names of departments that installed and that is currently responsible for the management of the medical device. The database also keeps the information as to whether the device awares the date, whether it is affected by the Y2K problem or not, how to solve the problem, reference home page address, and so on. The data was collected via internet search of the FDA web site and related of manufacturers homepages. To manage the Y2K problem effectively, the database should be updated regularly to include recent information.

• 한국컴퓨터정보학회논문지
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• 제25권2호
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• pp.181-188
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• 2020

본 연구는 응급구조과 대학생의 죽음의식, 연명치료중단에 대한 태도, 생명의료윤리인식의 수준을 파악하고, 생명의료윤리인식에 영향을 미치는 요인을 확인하기 위해 시도되었다. 연구대상은 D시에 소재한 일개대학 응급구조과 재학생 228명을 대상으로 시행하였으며, 자료수집은 2019년 4월부터 6월까지 자기보고식 구조화된 설문지를 이용하였다. 연구결과로 생명의료윤리인식과 연명치료중단에 대한 태도 간에는 정적 상관관계가 있는 것으로 분석되었다(r=.63, p<.001). 다중회귀분석결과, 생명의료윤리인식에 영향을 미치는 요인은 종교(β=.12)와 연명치료중단에 대한 태도(β=.61)로 41.0%의 설명력을 나타냈다. 따라서 생명의료윤리인식을 향상시키기 위해 응급구조과 학생들의 교육프로그램은 연명치료중단에 대한 태도에 초점을 맞추어야 할 것이다.

• 대한의생명과학회지
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• 제21권4호
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• pp.227-232
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• 2015

Epstein-Barr virus (EBV) has a pathogenic role in several lymphomas including diffuse large B-cell lymphoma (DLBCL). In this study, we detected EBV from formalin-fixed paraffin embedded (FFPE) tissues of DLBCL patients by RT-PCR and compared the sensitivity of the RT-PCR method to in situ hybridization (ISH) method. The RNA was extracted from 91 FFPE samples with DLBCL and amplified with primers targeting EBV-encoded small RNA (EBER) by RT-PCR. When using the RT-PCR method, 13 of 91 patients (14.3%) were positive and among these 13 cases, 7 cases (7.7%) were from > 50-year-old patients that is classified as EBV positive DLBCL of the elderly. In previous results using ISH method, 3 of 91 patients (3.3%) were positive and 2 case (2.4%) were older than 50-year-old. These results indicate that RT-PCR method used in this study shows a higher sensitivity than ISH method. The ratio of male versus female among the EBV positive samples was 1.2:1 with the ratio of male higher. If RT-PCR method having high sensitivity is used simultaneously as well as the ISH method providing the information of the EBV positive cellular location, it is expected that EBV will be more accurately detected.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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• pp.29-34
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• 2005

DNA microarray becomes a major tool for the investigation of global gene expression in all aspects of cancer and biomedical research. DNA microarray experiment generates enormous amounts of data and they are meaningful only in the context of a detailed description of microarrays, biomaterials, and conditions under which they were generated. MicroArray Gene Expression Data (MGED) society has established microarray standard for structured management of these diverse and large amount data. MGED MAGE-OM (MicroArray Gene Expression Object Model) is an object oriented data model, which attempts to define standard objects for gene expression. To assess the relevance of DNA microarray analysis of cancer research it is required to combine clinical and genomics data. MAGE-OM, however, does not have an appropriate structure to describe clinical information of cancer. For systematic integration of gene expression and clinical data, we create a new model, Cancer Genomics Object Model.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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• pp.479-480
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• 2007

고령사회에 접어들면서 연속적으로 심전도를 관찰할 필요가 있는 만성 심장 질환 환자의 수가 증가함에 따라, 이동형 심전도 측정 모듈을 활용하여 심전도를 분석하는 진단 시스템의 필요성이 크게 증가하고 있다. 이에 따라서 본 연구에서는 무구속 패치형 심전도 측정 모듈을 이용하여 심전도를 획득하고, 획득한 심전도를 무선으로 전송받아 Matched Filter를 이용하여 잡음을 제거하고 R-peak 검출을 수행하여 심장활동을 모니터링하고자 하였다.

• Genomics & Informatics
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• 제4권3호
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• pp.129-132
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• 2006

Toxicogenomics has recently emerged in the field of toxicology and the DNA microarray technique has become common strategy for predictive toxicology which studies molecular mechanism caused by exposure of chemical or environmental stress. Although microarray experiment offers extensive genomic information to the researchers, yet high dimensional characteristic of the data often makes it hard to extract meaningful result. Therefore we developed toxicant enrichment analysis similar to the common enrichment approach. We also developed web-based system graPT to enable considerable prediction of toxic endpoints of experimental chemical.

• International journal of advanced smart convergence
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• 제7권4호
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• pp.169-173
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• 2018

Iris diagnosis based on the color and texture information is one of a novel approach which can represent the current state of a certain organ inside body or the health condition of a person. In analysis of the iris images, there are critical image artifacts which can prevent of use interpretation of the iris textures on images. Here, we developed the iris diagnosis system based on a hand-held typed imaging probe which consists of a single camera sensor module with 8M pixels, two pairs of 400~700 nm LED, and a guide beam. Two original images with different light noise pattern were successively acquired in turns, and the light noise-free image was finally reconstructed and demonstrated by the proposed artifact removal approach.