• Title/Summary/Keyword: Biomedical Event

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The Simulation of Myocardium Conduction System using DEVCS and Discrete Time CAM (DEVCS 및 Discrete Time CAM을 이용한 심근 전도 시스템의 시뮬레이션)

  • Kim, K.N.;Nam, G.K.;Son, K.S.;Lee, Y.W.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.150-155
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    • 1997
  • Modelling and Simulation of the activation process for the myocardium is meaningful to understand special excitation conduction system in the heart and to study cardiac functions. In this paper, we propose two dimensional cellular automata model for the activation process of the myocardium and simulated by means of discrete time and discrete event algorithm. In the model, cells are classified into anatomically similar characteristic parts of heart; SA node, internodal tracks, AV node, His bundle, bundle branch and four layers of the ventricular muscle, each of which has a set of cells with preassigned properties, that is, activation time, refractory duration and conduction time between neighbor cell. Each cell in this model has state variables to represent the state of the cell and has some simple state transition rules to change values of state variables executed by state transition function. Simulation results are as follows. First, simulation of the normal and abnormal activation process for the myocardium has been done with discrete time and discrete event formalism. Next, we show that the simulation results of discrete time and discrete event cell space model is the same. Finally, we compare the simulation time of discrete event myocardium model with discrete time myocardium models and show that the discrete event myocardium model spends much less simulation time than discrete time myocardium model and conclude the discrete event simulation method Is excellent in the simulation time aspect if the interval deviation of event time is large.

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DEVS Modeling and Simulation for spectral characteristic on the strip of urin examination (뇨 분석용 strip의 분광학적 특성분석을 위한 DEVS 모델링 및 시뮬레이션)

  • Cho, Y.J.;Kim, J.H.;Nam, K.G.;Kim, J.H.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.145-149
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    • 1997
  • This paper describes a methodology for the development of models of discrete event system. The methodology is based on transformation of continuous state space into discrete one to homomorphically represent dynamics of continuous processes in discrete events. This paper proposes a formal structure which can coupled discrete event system models within a framework. The structure employs the discrete event specification formalism for the discrete event system models. The proposed formal structure has been applied to develop a discrete event specification model for the complex spectral density analysis of strip for urin analyzer system. For this, spectral density data of strip is partitioned into a set of Phases based on events identified through urine spectrophotometry. For each phase, a continuous system of the continuous model for the urine spectral density analysis has been simulated by programmed C++. To validate this model, first develop the discrets event specification model, then simulate the model in the DEVSIM++ environment. It has the similar simulation results for the data obtained from the continuous system simulation. The comparison shows that the discrete event specification model represents dynamics of the urine spectral density at each phase.

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Water Quality Monitoring by Snowmelt in Songcheon, Doam Lake Watershed (도암호 유역의 융설에 의한 수질 변화 모니터링)

  • Kwon, Hyeokjoon;Hong, Dahye;Byeon, Sangdon;Lim, Kyoungjae;Kim, Jonggun;Nam, Changdong;Hong, Eunmi
    • Journal of The Korean Society of Agricultural Engineers
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    • v.63 no.3
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    • pp.87-95
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    • 2021
  • The Doam Lake Watershed is one of Gangwon-do's non-point source management areas. This area has a lot of snowfall in winter, and it is expected that there will be a lot of soil erosion in early spring due to snow melting. In this study, snow melting was monitored in the Doam Lake watershed from February to 3, 2020. It was conducted to analyze the water quality changes by calculating the concentration of non-point source pollution caused by snowmelt, and to compare the concentration of water quality during snowmelt event with rainfall and non-rainfall event. As a result of water quality analysis, Event Mean Concentration (EMC) at the first monitoring was SS 33.9 mg/L, TP 0.13 mg/L, TN 4.33 mg/L, BOD 1.35 mg/L, TOC 1.84 mg/L. At the second monitoring, EMC were SS 81.3 mg/L, TP 0.15 mg/L, TN 3.12 mg/L, BOD 1.32 mg/L, TOC 3.46 mg/L. In parameter except SS, it showed good water quality. It is necessary to establish management measures through continuous monitoring.

Development of the Electrodermal Activity Monitoring System for the Evaluation of Train Driver's Arousal State (기관사의 각성상태 평가를 위한 소형 피부전기활성도 측정 시스템 개발)

  • Lim, Min-Gyu;Lee, Young-Jae;Lee, Kang-Hwi;Kang, Seung-Jin;Kim, Kyeung-Nam;Park, Hee-Jung;Yang, Heui-Kyung;Lee, Jeong-Whan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.63 no.9
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    • pp.1286-1293
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    • 2014
  • Typically, studies through the simulation system have been progressed, because the evaluation of the driver's arousal state about the service of a actual train has risk of safety for the driver. When configured event same as the real in simulation system, the ability to cope with an accident situation may be the same each other. But the difference in the state of tension or arousal will occur. In this study, requested to cooperate with the railways in order to escape from these constraints, and the target of the experiment was to real engineer service. I was set about experiment when the train was stopped as safe as possible. As a result, the beta wave of EEG signals that representing complex calculations or anxiety is increased rapidly on the basis of a flag station from at the time of departure. The size of the electrodermal activity signal in response to movement of the body gave a noticeable. In terms of HRV, if the train approach a flag station gradually and the R-R interval is narrowed. So that the driver can be estimated as arousal state. In accordance with this study, if the quantitative standard of arousal state be based on the driver's biosignals will provide, it will be able to take advantage of development the system that would prevent train accidents caused by human error.

Neural correlations of familiar and Unfamiliar face recognition by using Event Related fMRI

  • Kim, Jeong-Seok;Jeun, Sin-Soo;Kim, Bum-Soo;Choe, Bo-Young;Lee, Hyoung-Koo;Suh, Tae-Suk
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.78-78
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    • 2003
  • Purpose: This event related fMRI study was to further our understanding about how different brain regions could contribute to effective access of specific information stored in long term memory. This experiment has allowed us to determine the brain regions involved in recognition of familiar faces among non familiar faces. Materials and Methods: Twelve right handed normal, healthy volunteer adults participated in face recognition experiment. The paradigm consists of two 40 familiar faces, 40 unfamiliar faces and control base with scrambled faces in a randomized order, with null events. Volunteers were instructed to press on one of two possible buttons of a response box to indicate whether a face was familiar or not. Incorrect answers were ignored. A 1.5T MRI system(GMENS) was employed to evaluate brain activity by using blood oxygen level dependent (BOLD) contrast. Gradient Echo EPI sequence with TR/TE= 2250/40 msec was used for 17 contiguous axial slices of 7mm thickness, covering the whole brain volume (240mm Field of view, 64 ${\times}$ 64 in plane resolution). The acquired data were applied to SPM99 for the processing such as realignment, normalization, smoothing, statistical ANOVA and statistical preference. Results/Disscusion: The comparison of familiar faces vs unfamiliar faces yielded significant activations in the medial temporal regions, the occipito temporal regions and in frontal regions. These results suggest that when volunteers are asked to recognize familiar faces among unfamiliar faces they tend to activate several regions frequently involved in face perception. The medial temporal regions are also activated for familiar and unfamiliar faces. This interesting result suggests a contribution of this structure in the attempt to match perceived faces with pre existing semantic representations stored in long term memory.

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Increased Gamma-band Neural Synchrony by Pleasant and Unpleasant Visual Stimuli (긍정, 부정 감정 유발 시각자극에 의한 감마-대역 신경동기화 증가)

  • Yeo, Donghoon;Choi, Jeong Woo;Kim, Kyung Hwan
    • Journal of Biomedical Engineering Research
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    • v.39 no.2
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    • pp.94-102
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    • 2018
  • It is known that gamma-band activity (GBA) and phase synchrony (GBPS) are induced by emotional visual stimuli. However, the characteristics of GBA and GBPS according to different emotional states have not been identified. The purpose of this study is to investigate the changes in gamma-band neuronal synchronization induced by positive and negative emotional visual stimuli using electroencephalograms (EEGs). Thirteen healthy male subjects have participated in the experiment. The induced spectral power in gamma-band was the highest for negative stimuli, and the lowest for neutral stimuli in 300-2,000 ms after the stimulus onset. The inter-regional phase synchronization in gamma-band was increased in 500-2,000 ms, mainly between the bilateral frontal regions and the parieto-occipital regions. Larger number of significant connections were found by negative stimuli compared to positive ones. Judging from temporal and spatial characteristics of the gamma-band activity and phase synchrony increases, the results may imply that affective visual stimuli cause stronger memory encoding than non-emotional stimuli, and this effect is more significant for negative emotional stimuli than positive ones.

Implicit Distinction of the Race Underlying the Perception of Faces by Event-Related fMRI (Event-related 기능적 MRI 영상을 통한 얼굴인식과정에서 수반되는 무의식적인 인종구별)

  • Kim Jeong-Seok;Kim Bum-Soo;Jeun Sin-Soo;Jung So-Lyung;Choe Bo-Young
    • Investigative Magnetic Resonance Imaging
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    • v.9 no.1
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    • pp.43-49
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    • 2005
  • A few studies have shown that the function of fusiform face area is selectively involved in the perception of faces including a race difference. We investigated the neural substrates of the face-selective region called fusiform face area in the ventral occipital-temporal cortex and same-race memory superiority in the fusiform face area by the event-related fMRI. In our fMRI study, subjects (Oriental-Korean) performed the implicit distinction of the race while they consciously made familiar-judgments, regardless of whether they considered a face as Oriental-Korean or European-American. For race distinction as an implicit task, the fusiform face areas (FFA) and the right parahippocampal gyrus had a greater response to the presentation of Oriental-Korean faces than for the European-American faces, but in the conscious race distinction between Oriental-Korean and European-American faces, there was no significant difference observed in the FFA. These results suggest that different activation in the fusiform regions and right parahippocampal gyrus resulting from superiority of same-race memory could have implicitly taken place by the physiological processes of face recognition.

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Determination of filtering condition and threshold for detection of Gait-Cycles under Various Gait Speeds and Walkway Slopes (다양한 보행속도와 경사각에 대한 보행수 검출을 위한 필터링 조건과 역치의 결정)

  • Kwon, Yu-Ri;Kim, Ji-Won;Lee, Jae-Ho;Tack, Gye-Rae;Eom, Gwang-Moon
    • Journal of Biomedical Engineering Research
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    • v.30 no.6
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    • pp.516-520
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    • 2009
  • The purpose of this study is to determine optimal filtering condition and threshold for the detection of gait-cycles for various walkway slopes as well as gait velocities. Ten young healthy subjects with accelerometer system on thigh and ankle walked on a treadmill at 9 conditions (three speeds and three slopes) for 5 minutes. Two direction signals, i.e. anterior-posterior (AP) and superior-inferior (SI) directions, of each sensor (four sensor orientations) were used to detect specific events of gait cycle. Variation of the threshold (from -1G to 1G) and lowpass cutoff frequency (fc) were applied to the event detection and their performance was evaluated according to the error index (EI), which was defined as the combination of the accuracy and false positive rate. Optimal fc and threshold were determined for each slope in terms of the EI. The optimal fc, threshold and their corresponding EI depended much on the walkway slope so that their coefficients of variation (CV) ranged 19~120%. When all data for 3 slopes were used in the identification of optimal conditions for each sensor, the best error indices for all sensor orientations were comparable ranging 1.43~1.76%, but the optimal fc and threshold depended much on the sensor position. The result indicates that the gait-cycle detection robust to walkway slope is possible by threshold method with well-defined filtering condition and threshold.

Measurement of the Biological Active Point using the Bio-electrical impedance analysis based on the Adaptive Frequency Tracking Filter (적응주파수추적필터기반의 생체임피던스분석을 통한 생물학적활성점측정에 관한 연구)

  • Park, Hodong;Lee, Kyoungjoung;Yeom, Hojun
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.13 no.6
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    • pp.109-114
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    • 2013
  • The biological active points (BAP) are known as low resistance spots or good electro-permeable points. In this paper, a new method for BAP detection using the bio-impedance measurement system based on the adaptive frequency tracking filter (AFTF) and the transition event detector is presented. Also, the microcontroller process continuous time demodulation of the modulated signal by multi frequency components using the AFTF. The transition event detector based on the phase space method is applied about each frequency using the BAP equivalent model which is proposed.

Perspective Diversity of Domestic Stakeholders on Medical Device Adverse Event Reporting (의료기기 이상사례 보고에 대한 국내 이해관계자의 관점 차이)

  • Lee, Ye Jin;Yoon, Chiho;Choi, Soo Jeong;Kang, Youngjoon;Kim, Jin Kuk;Kwon, Bum Sun;Lee, You Kyoung;Nam, Ki Chang
    • Journal of Biomedical Engineering Research
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    • v.40 no.5
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    • pp.171-178
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    • 2019
  • This study was conducted to observe the differences in perspective of medical device adverse events and report exchange for domestic stakeholders. The post-market surveillance of medical device not only improves the usability and functionality of the device but also identifies new or growing risks caused by the device. APEC (Asia-Pacific Economic Cooperation) have established and operated post-market surveillance systems for medical devices based on IMDRF (International Medical Device Regulators Forum) and GHTF (Global Harmonization Task Force) guidelines. However, there are significant gaps in many aspects. It is essential to apply harmonized guidelines internationally but also to interpret and apply the guidelines consistently to report and exchange medical device adverse event in domestic. This study retrospectively analyzed the results of surveys conducted by providing examples of the adverse events and guidelines for post-market surveillance. The results of the study showed that there was a considerable difference in the judgment on the phase of using medical device for patient. In the case of medical device adverse event, different opinions shown according to knowledge and experience. Education and training are needed to have a harmonized perspective on the reporting and exchanging international guidelines of the adverse event for domestic stakeholders.