• 제목/요약/키워드: Biology and Life Science

검색결과 4,264건 처리시간 0.033초

Different oxidative burst patterns occur during host and nonhost resistance responses triggered by Xanthomonas campestris in pepper

  • Kwak, Youn-Sig;Han, Ki-Soo;Lee, Jung-Han;Lee, Kyung-Hee;Chung, Woo-Sik;Mysore, Kirankumar S.;Kwon, Young-Sang;Kim, Hee-Kyu;Bae, Dong-Won
    • Journal of Plant Biotechnology
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    • 제36권3호
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    • pp.244-254
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    • 2009

  • The hypersensitive reaction (HR) is the most common plant defense reaction against pathogens. HR is produced during both host- and nonhost-incompatible interactions. Several reports suggest that similarities exist between host and nonhost resistances. We assayed the pattern of generation of reactive oxygen species (ROS) and scavenging enzyme activities during nonhost pathogen-plant interactions (Xanthomonas campestris pv. campestris/Capsicum annuum L.) and incompatible host pathogen-plant interactions (Xanthomonas campestris pv. vesicatoria race1/Capsicum annuum L.). Both ${O_2}^-\;and\;H_2O_2 $ accumulated much faster during nonhost resistance when compared to the host resistance. The scavenging enzyme activities of superoxide dismutase (SOD), catalase (CAT) and peroxidase (POX) were also different during the host- and nonhost-incompatible interactions. CAT activity was much higher during nonhost resistance, and several new isozymes of SOD and POX were detected during nonhost resistance when compared to the host resistance. Lipoxygenase (LOX) activity was higher in host resistance than nonhost resistance during the early stages of infection. Interestingly, the nitric oxide (NO) radical accumulated equal amounts during both host and nonhost resistance at early stages of infection. Further studies are needed to determine the specific pathways underlying these differences between host and nonhost resistance responses.

  • https://doi.org/10.5010/JPB.2009.36.3.244 인용 PDF KSCI

miR-374 promotes myocardial hypertrophy by negatively regulating vascular endothelial growth factor receptor-1 signaling

  • Lee, Jong Sub;Song, Dong Woo;Park, Jei Hyoung;Kim, Jin Ock;Cho, Chunghee;Kim, Do Han
    • BMB Reports
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    • 제50권4호
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    • pp.208-213
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    • 2017

  • Vascular endothelial growth factor (VEGF) is an essential cytokine that has functions in the formation of new blood vessels and regression of cardiac hypertrophy. VEGF/VEGF-receptor-1 (VEGFR1) signaling plays a key role in the regression of cardiac hypertrophy, whereas VEGF/VEGFR2 signaling leads to cardiac hypertrophy. In this study, we identified the prohypertrophic role of miR-374 using neonatal rat ventricular myocytes (NRVMs). Our results showed that overexpression of miR-374 activated G protein-coupled receptor-mediated prohypertrophic pathways by the inhibition of VEGFR1-dependent regression pathways. Luciferase assays revealed that miR-374 could directly target the 3'-untranslated regions of VEGFR1 and cGMP-dependent protein kinase-1. Collectively, these findings demonstrated that miR-374 was a novel pro-hypertrophic microRNA functioning to suppress the VEGFR1-mediated regression pathway.

  • https://doi.org/10.5483/BMBRep.2017.50.4.165 인용 PDF KSCI

Reproductivity of Cloned Male Cat

  • Choi, E.G.;Lee, H.S.;Yin, X.J.;Ho, J.H.;Cho, E.M.;Kang, S.H.;Bae, I.H.;Cho, S.K.;Kong, I.K.
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 2005년도 제5회 발생공학 국제심포지엄 및 학술대회
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    • pp.129-129
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    • 2005

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Biogeochemical Activities of Microorganisms in Mineral Transformations: Consequences for Metal and Nutrient Mobility

  • Gadd, Geoffrey-M.;Burford, Euan-P.;Fomina, Marina
    • Journal of Microbiology and Biotechnology
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    • 제13권3호
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    • pp.323-331
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    • 2003

  • Bacteria and fungi are fundamental biotic components of natural biogeochemical cycles for metals and metalloids, and play important roles in dissolution, precipitation, oxidation and reduction processes. Some processes catalyzed by microorganisms also have important applications in environmental biotechnology in the areas of ore leaching and bioremediation.

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