• 제목/요약/키워드: Biology I

검색결과 3,171건 처리시간 0.042초

Effects of Regular Endurance Exercise or Acute-exercise and Rest on the Levels of Lipids, Carnitines and Carnitine Palmitoyltransferase-I in rats

  • Cha, Youn-Soo;Kim, Hyoung-Yon;Soh, Ju-Ryoun;oh, Suk-Heung
    • BMB Reports
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    • 제34권5호
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    • pp.434-439
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    • 2001

  • The effects of regular endurance exercise, or acute-exercise and rest on the levels of lipids, carnitines and carnitine palmitoyltransferase-I (CPT-I) were investigated in male Sprague-Dawley rats. The rats were exercise trained on a treadmill for 60 min per day for 60 days (long-term trained, LT), or non-trained for 59 days (NT) and exercised for 60 min on the 60th day. In NT rats, the levels of serum nonesterified carnitine (NEC), acidsoluble acylcarnitine (ASAC), and total carnitine (TONE) increased significantly during the post-exercise recovery period (PERP). In LT rats, ASAC, and TCNE, which increased right after the 60 min running session decreased to the levels of pre-exercise during the PERP. The levels of skeletal muscle ASAC in NT rats, which increased significantly by the acute-exercise, decreased to the pre-exercise levels during the PERP. However, the ASAC level in LT rats reached its peak at 4 h after running for 60 min. Liver triglyceride (TG) and total lipids (TL), which increased by the acute-exercise, decreased to the pre-exercise levels during the PERP in both NT and LT rats. CPT-I activity in NT rats increased significantly after 1 h of a 60-min exercise and slowly decreased to pre-exercise levels during the PERP. However, the CPT-I activity in LT rats, which increased significantly by the 60 min exercise, decreased slowly and reached its pre-exercise level within 8 h of the PERP. Northern blot analysis showed that the changes of CPT-I activities during the PERP coincided with changes in CPT-I mRNA levels. This study shows that both regular endurance exercise, and acute-exercise and rest, can influence differently the levels of carnitines, lipids and CPT-I in rats. The results suggest that regular endurance exercise, rather than the acute-exercise, can change effectively the distributions of carnitines, lipids and CPT-I in rats during exercise and rest.

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논우렁이 (Cipangopaludina chinensis Malleata)촉수 상피세포의 미세구조 (Ultrastructure of the Tentacular Epithelium in Cipangopaludina chinensis Malleata)

  • 송용직;김창식;김우갑;김창환
    • Applied Microscopy
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    • 제15권2호
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    • pp.80-88
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    • 1985

  • The tentacular epithelial cells of Cipangopaludina chinensis were studied with electron microscope. The tentacular epithelium consists of columnar supporting cells, numerous glandular cells and ciliated cells. Glandular cells are classified into three types; type I (mucous metachromasia cell), type II(mucous goblet cell) and type III. Ciliated cells are subdivided into two types; type I ciliated cell has cilia with typical axoneme(9+2), and type II ciliated cell has cilia with unusual axoneme.

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상피하 결합조직 이식편을 이용한 치근 피개술 (Root coverage using subepithelial connective tissue graft)

  • 김정현;허익;권영혁;박준봉;정종혁
    • Journal of Periodontal and Implant Science
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    • 제38권1호
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    • pp.91-96
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    • 2008

  • Purpose: One of the main objectives of periodontal reconstructive surgery is the coverage of exposed roots that occur due to gingival recession. and Aestheic concerns are usually the reason to perform root coverage procedure. This case report was performed to evaluate the effect of root coverage using subepithelial connective tissue graft(SCTG) on Miller's Class I marginal tissue recession. Materials and Methods: One patient, with two Miller's class I marginal tissue recession on both maxiallay canines, was treated with root coverage using SCTG (modified Nelson's technique). At baseline, the following measurements were recorded: 1) recession depth; 2) width of keratinized giniga. At 9, 10 months post-surgery, all clinical measurements were repeated. Result: 1) The mean root coverage from baseline to 9, 10 months post-surgery was 92.3%. 2) The mean recession depth decreased from 6.5 mm to 0.5 mm. 3) The mean width of keratinized gingiva increased from 1.25 mm to 3.5 mm. Conclusion: Within the above results, root coverage using SCTG is an effective procedure to cover Miller's class I marginal tissue recession defect. Also, patient with aesthetic concern could be satisfied with this result.

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Promoter Structure and Transcriptional Activity of Human Complement Receptor Type I (CR1) Gene

  • Kim, Jae-Hyun;Lee, Young-Ju;Nam, Ju-Ryoung;Shim, Hee-Bo;Choe, Soo-Young
    • Animal cells and systems
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    • 제7권1호
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    • pp.63-68
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    • 2003

  • Until recently, interest in human complement receptor type I (CR1) has focused on immune complex processing, which contributed to our understanding of regulatory mechanism of complement activation. However, the promoter structure and transcriptional regulation of human CR1 gene has not been clear. To study the unique regulation of human CR1 gene expression, we assessed promoter activity of the $5^1$-flanking region of human CR1 gene using transient transfection and gel mobility shift assays. In this study we demonstrated that NF-Y binds to the inverted CCAAT element and that the functional interaction with protein(s) which bind to the GC-rich motif may be necessary for optimal transcription of human CR1 gene. We also show that sequence elements which located at-95/58 and +45/+50 are important for optimal transcription of CR1 gene.

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