• 제목/요약/키워드: Biological studies

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우울장애의 신경생물학적 최신 지견 : 세로토닌 전달체에 대한 영상 유전학적 연구를 중심으로 (Current Understanding in Neurobiology of Depressive Disorders : Imaging Genetic Studies on Serotonin Transporter)

  • 함병주
    • 생물정신의학
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    • 제18권4호
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    • pp.176-180
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    • 2011
  • Depressive disorders have strong genetic components. However, conventional linkage and association studies have not yielded definitive results. These might be due to the absence of objective diagnostic tests, the complex nature of human behavior or the incomplete penetrance of psychiatric traits. Imaging genetics explores the influences of genetic variation on the brain function or structure. This technique could provide a more sensitive assessment than traditional behavioral measures in psychiatric studies. Imaging genetics is a relatively new field of psychiatric researches, and may improve our understanding on neurobiology of psychiatric disorders. In this review, current understanding in neurobiology of depressive disorders, especially imaging genetic studies on serotonin transporter will be discussed.

A Neurobiological Concept of Schizophrenia - Approach to Vulnerability -

  • Sato, Mitsumoto
    • 생물정신의학
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    • 제3권1호
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    • pp.37-45
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    • 1996
  • Recent studies on long-term outcome of schizophrenia revealed that schizophrenic symptoms recover in more than 50%, while it remains severe in less than 20% after 20 years or more from the onset. Psychopharmacological studies indicate that 75% of remitted schizophrenics may recur within 2 years after discontinuation of maintenance pharmacotherapy. In addition, family studies revealed that schizophrenic decompensation may occur significantly more frequent in discharged patients with high expressed emotion family than in low expressed emotion family. These findings strongly support a clinical validity of stress-vulnerability concept of schizophrenia which open a new viewpoint to two central problems in schizophrenia treatment, i.e. psychotic relapses and chronification of the fist episode schizophrenia. Moreover, recent psychopathological studies argue that schizophrenic symptoms are manifestations of psychological reaction secondary to a primary cognitive impairment(neurobiological vulnerability), which is originated in neurobiological changes in the brain. Recent approaches to the vulnerability to schizophrenic symptoms or schizophrenic decompensation are reviewed.

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아디포넥틴(adiponectin) 관련 연구논문 분석 (The analysis of Research about Adiponectin)

  • 변영순
    • Journal of Korean Biological Nursing Science
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    • 제12권3호
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    • pp.175-185
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    • 2010
  • Purpose: The purpose of this study is to analyze the trend of research on intervention using adiponectin and to find the utilization in nursing. Methods: A systematic literature review was conducted. From 2005 to 2009, the articles were searched electronically using the data base with the key words of adiponectin. The criteria for inclusion in review were 1) an randomized clinical trial (RCT), 2) human, 3) English or Korean language. Finally, 89 articles (41 domestic studies, 48 foreign studies) were included in the review. Results: The major findings of this study were as follows: 1) In domestic studies, subjects of obesity were 80.5%, and the most frequently used intervention were exercise (95.1%). 2) In foreign studies, there were interventions for subjects of obesity (55.1%), and diabetes (25.0%). 66.7% of studies were in medicine including 56.3% on medicine/hormone therapy. 3) Adiponectin was significantly increased in 31 domestic studies and 33 foreign studies. Conclusion: It needs to understand the influence of Adiponectin in nursing research and practice. The practical use of Adiponectin has to be considered in a sense that it may help determining the direction of the nursing research to provide more objective evidence for nursing practice.

간호 대학생을 위한 전문직간 약물관련 교육프로그램의 연구동향: 주제범위 문헌고찰 (Research trends in interprofessional education programs related to medication for undergraduate nursing students: a scoping review)

  • 정채윤;오재욱;추상희
    • Journal of Korean Biological Nursing Science
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    • 제26권2호
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    • pp.83-98
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    • 2024
  • Purpose: This study investigated how interprofessional education (IPE) related to medication for undergraduate healthcare students, including nursing students, has been designed and conducted. Furthermore, the outcomes of these IPE programs were evaluated. Methods: A scoping review was performed to understand the content and methods of IPE on medication for undergraduate healthcare students, including nursing students. A literature search was done using PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Research Information Sharing Service, and Korean Nursing Database in English between January 2000 and December 2022. In total, 14 papers were selected and reviewed. Results: Eleven research studies were conducted on the implementation of one-time IPE on medication safety or errors. Among them, six studies focused on providing IPE to nursing students alongside medical and pharmacy students, while three studies targeted nursing and medical students, and two studies focused on nursing and pharmacy students. The most commonly employed educational method was simulation, which was utilized in 12 studies. All studies consistently reported a positive impact on attitudes toward IPE and effective communication. Additionally, five studies evaluating medication knowledge reported improvements in participants' understanding of drugs. Conclusion: The effects of IPE related to medication for undergraduate nursing students have been confirmed. It is necessary to introduce IPE in the field of pharmacology.

실내환경에서 생물학적 인자에 대한 노출평가 (Exposure Assessment of Biological Agents in Indoor Environments)

  • 박주형
    • 한국환경보건학회지
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    • 제35권4호
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    • pp.239-248
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    • 2009
  • The Institute of Medicine of the National Academies of Science in the United States concluded in its 2004 report that excessive indoor dampness is a public health hazard and that its prevention should be a public health goal. Water damage in buildings, such as leaks from roofs, walls, or windows, may increase indoor moisture levels. Excessive dampness may promote microbial proliferation in indoor environments, increase occupants' exposure to microbial agents, and eventually produce adverse health effects in building occupants. Epidemiological studies to demonstrate the causal association between exposure to indoor microbial agents and health effects require reliable exposure assessment tools. In this review, I discuss various sampling and analytical methods to assess human exposure to biological agents in indoor environments, their strengths and weaknesses, and recent trends in research and practice in the USA.

Studies on the Biological Attributes of Scelionid Egg Parasitoid Psix striaticeps (Dodd) for the Control of Stink Bug Canthecona furcellata (Wolff) in Sericulture

  • Singh, R.N.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제4권2호
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    • pp.117-120
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    • 2002
  • Scelionid eggParasitoids Play an important role in biological control of some economically important pentatomids. Stink bug (Canthecona furcellatta Wolff,) is an important predator of Tasar silkworm larvae (Antheraea mylitta D.) and causes 30-40 percent loss in tasar silk industry. Psix striaticeps (Scelionid: Hymenoptera) has been found to be an important egg parasitoid. The parasitization potential of f striaticeps is mere than 60 percent and the sex ratio is female oriented. Studies indicate that the maintenance of existing scelionid population by avoiding harmful practices and the augmentation of scelionids either directly releasing them in the field or by indirectly making the field environment more favorable for them is an important aspect to control the pentatomid population in sericulture. Female bias sex ratio is advantageous to increase the parasitoid population in the field. 24-hour-old egg of stink bug and one-day old parasitoid is suitable for producing maximum progeny. 1 : 30 of parasitoid: host ratio is needed to regulate the estimated population in silkworm rearing field.

Characteristics and distribution of terpenes in South Korean forests

  • Lee, Jaeseok;Cho, Kyoung Sang;Jeon, Youngjae;Kim, Ji Beom;Lim, Young-ran;Lee, Kyungho;Lee, Im-Soon
    • Journal of Ecology and Environment
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    • 제41권5호
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    • pp.132-141
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    • 2017
  • The importance of forests continues to increase throughout the world, and one of the reasons is that a forest is a major place to emit terpenes, which have been reported to be beneficial to human health. In South Korea, forests occupy about 64% of the total land area and consist mainly of pine and oak trees. Since only a limited number of forests have been analyzed to date, a comprehensive understanding of terpenes emitted from regional forests remains in its infancy in Korea. Here, to gain insights into terpenes from regional forests located in South Korea, we review the characteristics of Korean forests and recent studies on major terpenes emitted from regional forests as well as from native trees dominant in South Korea. We also discuss meteorological factors that affect the terpene emissions in Korean forests. In conclusion, 18 types of terpenes were detected in Korean forests and their compositions in different forests are largely dependent on the dominant plant species in the forest. Moreover, terpene emissions in Korean forests are affected by various environmental factors, including temperature, amount and duration of daylight, season, and age of trees. To improve the understanding of the characteristics of terpene distribution, more studies are required on the terpene production of Korean forests in various regions.