• Title/Summary/Keyword: Biological Materials

Search Result 2,353, Processing Time 0.029 seconds

Functional Li-M (Ti, Al, Co, Ni, Mn, Fe)-O Energy Materials

  • Kim, In Yea;Shin, Seo Yoon;Ko, Jea Hwan;Lee, Kang Soo;Woo, Sung Pil;Kim, Dong Kyu;Yoon, Young Soo
    • Journal of the Korean Ceramic Society
    • /
    • v.54 no.1
    • /
    • pp.9-22
    • /
    • 2017
  • Many new functional materials have been studied for efficient production and storage of energy. Many new materials such as sodium-based and sulfide-based materials have been proposed for energy storage, but research on Li batteries is still dominant. Due to the influence of environmental concerns regarding nuclear energy, interest in and research on fusion power are steadily increasing. For the commercialization of nuclear fusion, a design standard based on a considerable level of physical analysis and modeling is proposed. Nevertheless, limitations of existing materials in nuclear fusion environments limit practical applications. Tritium propagation material for continuous fusion reaction is one of the core materials, and therefore research on this material is being carried out intermittently. The key material for Li-based energy storage and tritium generation is the functional material Li-M-O. In this review, a structural description of functional Li-M-O system materials and technical trends for its applications are introduced.

Medicolegal Study on Human Biological Material as Property (인체 유래 물질의 재산권성에 대한 의료법학적 고찰)

  • Lee, Ung-Hee
    • The Korean Society of Law and Medicine
    • /
    • v.10 no.2
    • /
    • pp.455-492
    • /
    • 2009
  • (Background) Recent biotechnological breakthroughs are shedding new lights on various ethical and legal issues about human biological material. Since Rudolph Virchow, a German pathologist, had founded the medical discipline of cellular pathology, issues centering around human biological materials began to draw attention. The issues involving human biological materials were revisited with more attention along with series concerns when the human genome map was finally completed. Recently, with researches on human genes and bioengineering reaping enormous commercial values in the form of material patent, such changes require a society to reassess the present and future status of human tissue within the legal system. This in turn gave rise to a heated debate over how to protect the rights of material donors: property rule vs. no property rule. (Debate and Cases) Property rule recognizes the donors' property rights on human biological materials. Thus, donors can claim real action if there were any bleach of informed consent or a donation contract. Donors can also claim damages to the responsible party when there is an infringement of property rights. Some even uphold the concept of material patents overtaking. From the viewpoint of no property rule, human biological materials are objects separated from donors. Thus, a recipient or a third party will be held liable if there were any infringement of donor's human rights. Human biological materials should not be commercially traded and a patent based on a human biological materials research does not belong to the donor of the tissues used during the course of research. In the US, two courts, Moore v. Regents of the University of California, and Greenberg v. Miami Children's Hospital Research Institute, Inc., have already decided that research participants retain no ownership of the biological specimens they contribute to medical research. Significantly, both Moore and Greenberg cases found that the researcher had parted with all ownership rights in the tissue samples when they donated them to the institutions, even though there was no provision in the informed consent forms stating either that the participants donated their tissue or waived their rights to ownership of the tissue. These rulings were led to huge controversy over property rights on human tissues. This research supports no property rule on the ground that it can protect the human dignity and prevent humans from objectification and commercialization. Human biological materials are already parted from human bodies and should be treated differently from the engineering and researches of those materials. Donors do not retain any ownership. (Suggestions) No property rule requires a legal breakthrough in the US in terms of donors' rights protection due to the absence of punitive damages provisions. The Donor rights issue on human biological material can be addressed through prospective legislation or tax policies, price control over patent products, and wider coverage of medical insurance. (Conclusions) Amid growing awareness over commercial values of human biological materials, no property rule should be adopted in order to protect human dignity but not without revamping legal provisions. The donors' rights issue in material patents requires prospective legislation based on current uncertainties. Also should be sought are solutions in the social context and all these discussions should be based on sound medical ethics of both medical staffs and researchers.

  • PDF

Standard based Deposit Guideline for Distribution of Human Biological Materials in Cancer Patients

  • Seo, Hwa Jeong;Kim, Hye Hyeon;Im, Jeong Soo;Kim, Ju Han
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.14
    • /
    • pp.5545-5550
    • /
    • 2014
  • Background: Human biological materials from cancer patients are linked directly with public health issues in medical science research as foundational resources so securing "human biological material" is truly important in bio-industry. However, because South Korea's national R and D project lacks a proper managing system for establishing a national standard for the outputs of certain processes, high-value added human biological material produced by the national R and D project could be lost or neglected. As a result, it is necessary to develop a managing process, which can be started by establishing operating guidelines to handle the output of human biological materials. Materials and Methods: The current law and regulations related to submitting research outcome resources was reviewed, and the process of data 'acquisition' and data 'distribution' from the point of view of big data and health 2.0 was examined in order to arrive at a method for switching paradigms to better utilize human biological materials. Results: For the deposit of biological research resources, the original process was modified and a standard process with relative forms was developed. With deposit forms, research information, researchers, and deposit type are submitted. The checklist's 26 items are provided for publishing. This is a checklist of items that should be addressed in deposit reports. Lastly, XML-based deposit procedure forms were designed and developed to collect data in a structured form, to help researchers distribute their data in an electronic way. Conclusions: Through guidelines included with the plan for profit sharing between depositor and user it is possible to manage the material effectively and safely, so high-quality human biological material can be supplied and utilized by researchers from universities, industry and institutes. Furthermore, this will improve national competitiveness by leading to development in the national bio-science industry.

Particle Tracking Microrheology and its application to dilute viscoelastic materials (입자추적 미세유변학의 묽은 점탄성 물질에 대한 응용)

  • Yim Yoon-Jae;Lee Sung-Sik;Ahn Kyung-Hyun;Lee Seung-Jong
    • Proceedings of the Korean Society of Rheology Conference
    • /
    • 2006.06a
    • /
    • pp.61-64
    • /
    • 2006
  • Soft materials, such as polymer solutions, gels and filamentous protein materials in cells, show complicated behavior due to their complex structures and dynamics with multiple characteristic time and length scales. Several complementary techniques have been developed to measure viscoelastic of soft materials. Especially, particle tracking microrheology, using the Brownian motion of particles in a medium to get rheological properties, has recently been improved both theoretically and experimentally. Compared to other conventional methods, video particle tracking microrheology has some advantages such as small sample volume, detecting spatial variation of local rheological properties, and less damage to sample materials. With these advantages, microrheology is more suitable to measure the properties of complex materials than other mechanical rheometries.

  • PDF

Effect of Different Substrates and Casing Materials on the Growth and Yield of Calocybe indica

  • Amin, Ruhul;Khair, Abul;Alam, Nuhu;Lee, Tae-Soo
    • Mycobiology
    • /
    • v.38 no.2
    • /
    • pp.97-101
    • /
    • 2010
  • Calocybe indica, a tropical edible mushroom, is popular because it has good nutritive value and it can be cultivated commercially. The current investigation was undertaken to determine a suitable substrate and the appropriate thickness of casing materials for the cultivation of C. indica. Optimum mycelial growth was observed in coconut coir substrate. Primordia initiation with the different substrates and casing materials was observed between the 13th and 19th day. The maximum length of stalk was recorded from sugarcane leaf, while diameter of stalk and pileus, and thickness of pileus were found in rice straw substrate. The highest biological and economic yield, and biological efficiency were also obtained in the rice straw substrate. Cow dung and loamy soil, farm-yard manure, loamy soil and sand, and spent oyster mushroom substrates were used as casing materials to evaluate the yield and yield-contributing characteristics of C. indica. The results indicate that the number of effective fruiting bodies, the biological and economic yield, and the biological efficiency were statistically similar all of the casing materials used. The maximum biological efficiency was found in the cow dung and loamy soil casing material. The cow dung and loamy soil (3 cm thick) was the best casing material and the rice straw was the best substrate for the commercial cultivation of C. indica.

Study of Development of Selective Removal Adsorption Ion Exchange Resin Materials for Fabricated with Chemical-biological Cloth by QFD (QFD 기법을 이용한 특정 유해가스 노출제어 이온선택성 보호복 소재개발연구)

  • Song, Hwa Seon;Koo, Il Seob;Kim, In Sik
    • Journal of Korean Society for Quality Management
    • /
    • v.43 no.3
    • /
    • pp.359-372
    • /
    • 2015
  • Purpose: Through studying the expert's and non-experts panel responses to the questions regarding the attributes of chemical-biological protection cloth quality in terms of the levels of customer demand and technical factors has been studied. We are applied to a QFD matrix with find out the relationship between the selective removal efficiency of chemical-biological cloth and the guidelines of technical approach. Methods: We fabricated several composite of ion-exchange resins with selectively permeable performance designed to facilities water vapor transport and selective adsorption of the harmful gases. With these materials, we characterized on the selectively permeable performance to identify ion-exchange resin with chemical-biological protective cloth. Results: Results showed that ion exchange materials possessed performance with selectively efficiencies as NH3, SOx, NOx and HCl gas. The selective adsorption amount of ammonia and hydrogen gases were $90-80{\mu}g/g$ with TRILITE SCR-BH sulfonated ion exchange resin. The PP non-woven/ion exchange resin adsorbent materials possessed performance with water vapor permeability were 1,100-1,350 g/m2/day, it's was two times high value compare with activated carbon. With these materials, we characterized selectively removal efficiency to identify new ion-exchange material with chemical-biological protective capability. Conclusion: This study shows that a QFD aids in deciding with of the adsorption parameters to optimized with chemical-biological protection cloth manufacturing.

Application of Nanoparticles for Materials Recognition using Peptide Phage Display Technique- Part I: Preliminary study using LaPO4 and TiO2 nanoparticles (Peptide phage display 기술을 이용한 나노입자의 materials recognition 응용 - Part I: LaPO4 및 TiO2 나노입자를 이용한 기초연구)

  • Lee, Chang-Woo;Kim, Min-Jung;Standaert, R.;Kim, Seyeon;Owens, E.;Yan, Jun;Choa, Yong-Ho;Doktycz, M.;Lee, Jai-Sung
    • Korean Journal of Metals and Materials
    • /
    • v.46 no.1
    • /
    • pp.6-12
    • /
    • 2008
  • Peptides with specific sequences against $LaPO_4$ and $TiO_2$ nanoparticles were discovered through peptide phage display technique as an application to biomolecular recognition of inorganic materials. Sequencing results showed that a motif consisting of serine and proline was commonly expressed in specific sequences. It was postulated that serine directly bound to nanoparticles using its terminal hydroxyl (OH) group. In this sense, oxygen atom seemed to work as a ligand to metal ions and hydrogen atom as a H-bond donor, was thought to bind to the oxygen atoms or the hydroxyl groups on particle surface. Also, it was expected that proline assists serine to make an ideal van der Waals contact between serine and nanoparticles, which optimizes the binding of peptide onto surface.