• Title/Summary/Keyword: Biochemical information

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Study of biochemical factors and stress in Korean Adults (한국인 성인에서 스트레스에 대한 생화학적 요인 분석 연구)

  • Lee, Bum Ju
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.31-36
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    • 2021
  • Stress is a common risk factor for health and is associated with the endocrine gland and immune system. Studies on the association between stress and biochemical factors have been conducted worldwide, but studies on the association have been rare in South Korea. Therefore, the aims of this study are to analyze the relationship of stress with demographic information and biochemical factors for domestic adults and derive risk factors for stress. For data analysis, stress and normal groups were analyzed using binary logistic regression. In both men and women, age and average daily sleep time during the weekday were highly associated with stress, and the depression score (Patient Health Questionnaire-9) was also highly related with stress. In women, white blood cell levels were highly associated with stress, and in men, red blood cell levels were highly related with stress. These findings will contribute to the prevention of stress and the national health in the future.

Data Modeling for Cell-Signaling Pathway Database (세포 신호전달 경로 데이타베이스를 위한 데이타 모델링)

  • 박지숙;백은옥;이공주;이상혁;이승록;양갑석
    • Journal of KIISE:Databases
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    • v.30 no.6
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    • pp.573-584
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    • 2003
  • Recent massive data generation by genomics and proteomics requires bioinformatic tools to extract the biological meaning from the massive results. Here we introduce ROSPath, a database system to deal with information on reactive oxygen species (ROS)-mediated cell signaling pathways. It provides a structured repository for handling pathway related data and tools for querying, displaying, and analyzing pathways. ROSPath data model provides the extensibility for representing incomplete knowledge and the accessibility for linking the existing biochemical databases via the Internet. For flexibility and efficient retrieval, hierarchically structured data model is defined by using the object-oriented model. There are two major data types in ROSPath data model: ‘bio entity’ and ‘interaction’. Bio entity represents a single biochemical entity: a protein or protein state involved in ROS cell-signaling pathways. Interaction, characterized by a list of inputs and outputs, describes various types of relationship among bio entities. Typical interactions are protein state transitions, chemical reactions, and protein-protein interactions. A complex network can be constructed from ROSPath data model and thus provides a foundation for describing and analyzing various biochemical processes.

The effects of education for hemodialysis patients with a family caregiver on self-care practice and blood biochemical parameters (혈액투석 환자의 가족참여교육이 자가간호수행과 혈액생화학적 지표에 미치는 영향)

  • Park, Ji Hyun;Choi, Hyunkyung
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.2
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    • pp.487-498
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    • 2016
  • The purpose of this study was to identify the effects of education for hemodialysis patient with a family caregiver on self-care practice and on blood biochemical parameters. A nonequivalent control group pretest and posttest design has been employed for analysis. Among hemodialysis patients in C university hospital located in Daegu, 56 subjects, 28 in experimental and 28 in control group, participated in the study from April to May in 2015. The experimental group whose family caregiver participated in education for hemodialysis patient reported significant differences in self-care practice (t=3.36, p=.001) and serum potassium level (t=2.78, p=.007) from the control group whose family caregiver did not participate. Considering positive effects of family education, we suggest education programs incorporating family caregivers be used as an effective nursing intervention.

Measurement of cellulase activities

  • 편집실
    • The Microorganisms and Industry
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    • v.11 no.1
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    • pp.21-33
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    • 1985
  • 이글은 다음과 같이 구성되어져 있다. preface 1) introduction 2) general information 3) folin protein determination 4) cellobiase assay 5) filter paper assay for saccharifying cellulase 6) carboxymethyl cellulase assay for endo-.betha.-1,4-glucanase 7) additional assay procedure for endoglucanase 8) evalutaiton of cellulase under process conditions 9) general remartks, references.

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Current Status of Skin Cornification

  • 정수일
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.25 no.2
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    • pp.27-34
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    • 1999
  • Biochemical, enzymatic, immunological, and morphological evidences on ceramide and other lipids lamellae formation, assembly of component proteins of CE and expression and distribution of TGases provided better understanding of CE formation. Pathophysiology of some of the genetic disease is beginning to be clarified. Hope we can utilize the information gained in understanding CE formation would expedite the development of patient treatment processes.

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A Review on Structure, Modifications and Structure-Activity Relation of Quercetin and Its Derivatives

  • Magar, Rubin Thapa;Sohng, Jae Kyung
    • Journal of Microbiology and Biotechnology
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    • v.30 no.1
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    • pp.11-20
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    • 2020
  • Quercetin and its derivatives are important metabolites that belong to the flavonol class of flavonoids. Quercetin and some of the conjugates have been approved by the FDA for human use. They are widely distributed among plants and have various biological activities, such as being anticancer, antiviral, and antioxidant. Hence, the biosynthesis of novel derivatives is an important field of research. Glycosylation and methylation are two important modification strategies that have long been used and have resulted in many novel metabolites that are not present in natural sources. A strategy for modifying quercetin in E. coli by means of glycosylation, for example, involves overexpressing respective glycosyltransferases (GTs) in the host and metabolic engineering for increasing nucleoside diphosphate sugar (NDP-sugar). Still others have used microorganisms other than E. coli, such as Streptomyces sp., for the biotransformation process. The overall study of the structural activity relationship has revealed that modification of some residues in quercetin decreased one activity but increased others. This review summarizes all of the information mentioned above.

A Case of Non-alcoholic Steatohepatitis Treated with Herbal Medicine

  • Son, Chang-Gue
    • The Journal of Korean Medicine
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    • v.32 no.3
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    • pp.50-54
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    • 2011
  • Objective: To understand the characteristic of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and study the traditional Korean medicine (TKM)-based strategies or therapeutics for them. Methods: A male patient with NASH was treated with only Oriental therapies, and then the clinical outcome was evaluated by serum biochemical parameters and radiographs. Result: The clinical and biochemical values of the patient fluctuated over three years according to the treatments and cessation of herbal medicines. Conclusion: NASH or NAFLD are now prevalent and these disorders could be targets of TKM, and this case report would provide useful information.

Effect of Irradiation on the Biological System in Plants (식물의 생물학적 시스템에 대한 방사선의 상호작용)

  • Choi, Jong-Il;Kim, Jin-Kyun
    • Journal of Plant Biotechnology
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    • v.40 no.3
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    • pp.111-124
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    • 2013
  • Research on the basic interaction of radiation with biological systems has contributed to human society through various applications in pharmaceutical, medicine, agriculture and other technological developments. In the agricultural sciences and food technology sectors, the last few decades have witnessed a large number of pertinent works regarding the utilization of radiation for evolution of superior varieties of agricultural crops of economic importance. This review presents general information about the effect of radiation on plant specificity, dose response, and benefits. There has been summarized of the effects observed after exposure and influenced by several factors including plant characteristics and radiation features. We also report on the effect of ${\gamma}$-irradiations on plants, focusing on metabolic alterations, modifications of growth and development and changes in biochemical pathways.

Reduction of Inadequate Sample Collection (부적합 검체 감소방안)

  • Kim, Byeong-Hak;Myeong, Hwa-Ryeon;Lee, Jeong-Gyu;Park, Su-Hui;Lee, Jae-Hyeok
    • Journal of Korea Association of Health Promotion
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    • v.4 no.1
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    • pp.115-124
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    • 2006
  • Basically, diagnosis is a comprehensive judgement of the biochemical data which were collected from the patient directly. Therefore, no matter what kinds of well-managed data control are there, if data sample itself is not perfectly appropriate for any reason. we can not rule out high possibility of misunderstanding or wrong diagnosis. Among many possible reasons inadequate sample were collected maybe three situation and circumstances could be assumed as follows. 1. Client did not know what they are supposed to do for sampling 2. Technicians are to qualified or less-experienced on the job 3. Wrong managing or careless treat of the biochemical data sample If it is true, we could manage these problems to be solved through the information sharing and education. In order to verify this hypothesis, actually 5,800 cases were studied from January to August this year. Owing to the thorough education the rate of unappropriated samples reduced to 0.4% from 1.2%. This outcome strongly support the hypothesis of the mutual relation between the proper sample and well-designed education in advance. The importance of information sharing on right process of sample collection should be emphasized.

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