• Title/Summary/Keyword: Biochemical factors

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Development of Animal Health Monitoring System Model IV. Analysis of Risk Factors in Biochemical Part (동물(젓소)건강 Monitoring System 모델 개발 IV. 혈액 성분의 생화학적 위해요소 분석)

  • 김곤섭;김종수;최민철;라도경;김용환;김충희
    • Journal of Veterinary Clinics
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    • v.17 no.1
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    • pp.28-31
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    • 2000
  • An animall health monitoring system in Gyeongnam area(near Chinju) was studied to analysis of biochemical risk factors in 617 herds. Clinical serum factors such as glutamate oxaloacetate transaminase(GOT), glutamate pyruvate transaminase(GPT), Ca, P, Mg, glucose, and cholesterol were measured with automatic biochemical analyzer(Ra-X7T Techmmicon, USA). In serum analysis, 613 cattle were within normal llimits(GOT: 9.5-85 IU-dl, GPT: 25-77IU/dl, total protein: 5.8-8.5g/dl, Ca: 4.2-12.4mg/dl, P: 4.6-9.7mg/dl, Mg: 1.5-3.0mg/dl, glucose: 48-120mg/dl, Cholesterol: 70-170mg/dl), the other cattle showed high glucose and high cholesterol level. It is proposed that clinical serum factors to be estimated may be valuable for developing of animal health monitoring system model.

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Metabolic Syndrome Related with Serum Biochemical Factors Affecting Serum GGT at Transitional Ages in Gumi

  • Seok, Seong-Ja
    • Biomedical Science Letters
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    • v.16 no.4
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    • pp.317-322
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    • 2010
  • This study has been done with 1,431 subjects who visited Health Promotion Centers of the hospitals in Gumi for National Health Screening Program for People at Transitional Ages from April to December 2007. Serum biochemical tests related with metabolic syndrome were performed. Among biochemical factors related with metabolic syndrome, the mean values of serum glucose, AST, ALT, triglyceride and HDL cholesterol except LDL cholesterol were significantly higher in males than in females, so a significant difference by sex was observed (P<0.001). AST, ALT, triglyceride and HDL were thought to be significantly affecting serum GGT for males. In contrast, ALT and HDL cholesterol were important factors for females (P<0.001). For both sexes, serum glucose and LDL cholesterol did not produce any meaningful effect on serum GGT. In males AST, ALT and HDL cholesterol were associated with high risk of abnormality of serum GGT and in females AST, ALT and LDL cholesterol were related with high risk of abnormality of serum GGT. Therefore, AST and ALT showed a significant effect on abnormality of serum GGT in both males and females. It was observed that males exhibited significantly high correlation between metabolic syndrome related biochemical factors and serum GGT than females, and their influence on abnormality of serum GGT was also higher in males than in females. Therefore, serum GGT tests performed for health screening are considered to be useful for managements of cardiovascular diseases and metabolic syndrome as well as liver function test.

Unraveling the Contributing Factors of Sarcopenia in Young Korean Male Adults: A Study of Occurrence, Somatometric, Biochemical, and Behavioral Characteristics

  • Jongseok Hwang
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.3
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    • pp.21-30
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    • 2023
  • PURPOSE: The present study evaluated the occurrence, somatometric, biochemical, and behavioral characteristics of young Korean sarcopenic males aged between 30 to 39 years. METHODS: The study involved a total of 1,546 participants. These individuals were divided into two distinct groups based on their skeletal muscle mass index. Of these, 49 participants were categorized into the sarcopenia group, while the remaining 1,497 individuals were placed in the normal group. The researchers analyzed the occurrence of sarcopenia, somatometric, biochemical, and behavioral characteristics such as height, weight, body mass index (BMI), waist circumference (WC), skeletal muscle mass index, fasting glucose (FG), triglyceride and total cholesterol (TC) levels, systolic (SBP) and diastolic blood pressure (DBP), and the drinking and smoking status. A complex sampling data analysis was performed. RESULTS: The weighted occurrence of sarcopenia was found to be 3.24%, (95% confidence interval (CI) of 2.39% to 4.36%). The somatometric contributing factors were height, BMI, and WC (p < .05). Triglyceride and TC levels exhibited statistically significant differences in the biochemical variables (p < .05). The behavioral characteristics, including the drinking and smoking status, had no statistical significance (p > .05). CONCLUSION: This study identified specific occurrences of sarcopenia and contributing factors in young Korean men.

Preoperative Levels of Hematological and Biochemical Indices Affect Perioperative Variables in Adult Patients with Coronary Artery Bypass Graft Surgery

  • Choi, Seok-Cheol;Cho, Byung-Kyu;Lee, Yong-Hwan;Chang, Kyung-Soo
    • Biomedical Science Letters
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    • v.16 no.4
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    • pp.247-258
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    • 2010
  • The objective of this research was to evaluate the relationships of preoperative (Pre-OP) levels of hematological and biochemical indices to perioperative variables in patients that underwent coronary artery bypass graft surgery (CABG). Pre-OP levels of hematological factors [total white blood cells (T-WBC), erythrocytes, hemoglobin, hematocrit, glycohemoglobin A1c (HbA1c), or platelet] were negatively or positively related with biochemical indices [alanine aminotransferase (ALT), bilirubin, glucose, fructosamine, triglyceride, and high density lipoprotein cholesterol (HDL)]. Pre-OP levels of hematological factors and biochemical indices were negatively or positively correlated with echocardiographic variables. Pre-OP level of HbA1c had a relationship with C-reactive protein. Pre-OP levels of aspartate aminotransferase (AST), ALT, HDL, glucose, fructosamine, or blood urea nitrogen (BUN) were positively or negatively associated with Pre-OP levels of cardiac markers (brain natriuretic peptide, troponin-I, creatine kinase isoenzyme 2, or CRP). Pre-OP levels of hematological factors (excepting T-WBC) related with operation time (OPT), postoperative mechanical ventilation time (POMVT), intensive care unit-period (ICU-period) or hospitalization. Pre-OP levels of AST, ALT, bilirubin, triglyceride, HDL, low dwensity lipoprotein, fructosamine, or BUN were positively or negatively correlated with OPT, graft numbers, POMVT, ICU-period or hospitalization. Retrospective this study reveals that Pre-OP levels of hematological and biochemical markers are associated with echocardiographic variables, several cardiac markers and postoperative outcomes, suggesting that Pre-OP levels of hematological and biochemical markers may be useful predictors for the diagnosis and prognosis of coronary artery disease.

Study of biochemical factors and stress in Korean Adults (한국인 성인에서 스트레스에 대한 생화학적 요인 분석 연구)

  • Lee, Bum Ju
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.31-36
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    • 2021
  • Stress is a common risk factor for health and is associated with the endocrine gland and immune system. Studies on the association between stress and biochemical factors have been conducted worldwide, but studies on the association have been rare in South Korea. Therefore, the aims of this study are to analyze the relationship of stress with demographic information and biochemical factors for domestic adults and derive risk factors for stress. For data analysis, stress and normal groups were analyzed using binary logistic regression. In both men and women, age and average daily sleep time during the weekday were highly associated with stress, and the depression score (Patient Health Questionnaire-9) was also highly related with stress. In women, white blood cell levels were highly associated with stress, and in men, red blood cell levels were highly related with stress. These findings will contribute to the prevention of stress and the national health in the future.

Study of Novel Markers for Early Diagnosis of Cardiovascular Diseases

  • Kang Jae Heon;Han Jung Soon;Kim Kyung A;Song Hong Ji
    • Journal of Community Nutrition
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    • v.6 no.3
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    • pp.155-163
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    • 2004
  • In our country, cardiovascular disease (CVD) and Coronary heart diseases (CHD) are the leading causes of death. It is well known that CHD is multifactorial, involving environmental factors such as diet, level of exercise and cigarette smoking, and inherited factors. According to the statistical data in 2003, the cause of death with the highest mortality was including hypertension, ischemic heart disease and atherosclerosis, which accounted for $24.7\%$ of total mortality. In spite of, there have been few study reports on the change of biochemical markers and mechanisms concerned. The development of biochemical markers is required for an early diagnosis and treatment of cardiovascular diseases that are related with dietary habits of Korean people enjoying mixtures of traditional dietary style and westernized food-styles. Therefore, the most efficient cost-saving biochemical marker was established in this study, through analysis of biochemical markers related with dietary habits which are susceptibly being changed in association to cardiovascular diseases from the pre-disease phase, and through reanalysis and assessment of early diagnosis of and preventive effects of diagnosis of cardiovascular diseases by demographical character including sex, age, and socioeconomic level with use of biochemical markers that are identified and selected among the parameters in consideration of the effectiveness and appropriateness of early diagnosis of diseases. The appropriateness of biochemical markers was reviewed by professionals (medical, pharmaceutical area and food/ nutrition area) and CRP(C-Reactive Protein) and was identified to be possible in Korea. It is thought that these biochemical markers may be used as the basic data for early diagnosis and prevention of cardiovascular diseases (CVD) which may be used for Korean people.

Review of Biochemical Bone Metabolism Markers Change in Osteoporosis Incidence Factors (골다공증 발생요인에 따른 골대사 생화학적 지표의 변동 고찰)

  • Lee Hye-Ja
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.412-422
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    • 2002
  • The use of biochemical markers of bone turnover may be particular interest in the investigation of bone disorders with osteoporosis. Serum osteocalcin(OC), total alkaline phosphatase and procollagen C, reflecting bone formation, and urinary pyridinium cross-links excretion, reflecting bone reabsorption have been measured in hyperthyroidism, postmenopause women, after testosterone supplementation, androgen, testosterone and estrogen deficiency, bone mineral density degree, age duration. Bone marks which is reflect to metabolic bone disorders are biochemical indices method to measure enzyme activity about bone formation, bone absorption and bone components in blood or urine. Bone metabolism biochemical marks are correlated with osteophorotic agents and also represent significantly different between bone mineral density and bone biochemical marks. Therefore if we develope and use bone metabolism marks which have higher sensitivity and specificity in bone formation and bone absorption, I think that these bone biochemical marks can have utility in the clinical application to predict osteoporosis risk group, bone loss, bone fracture and response degree to treatment of osteoporosis risk groups.

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Risk assessment of Nitrogen Dioxide exposure on Welders

  • Jeong Seong-Wook;Song Seung-Hyg;Park Heung-Jai
    • Journal of Environmental Science International
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    • v.14 no.1
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    • pp.9-14
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    • 2005
  • This study evaluated the hazard caused by $NO_{2}$, an oxidant generated in the process of welding. We com­pared hematological and biochemical parameters in workers who chronically inhale $NO_{2}$ and office workers not exposed to $NO_{2}$. $NO_{2}$ exposure affected the hematological and biochemical parameters. Increasing $NO_{2}$ concen­trationincreased the number of leukocytes, while decreasing the number of erythrocytes. Blood urea nitrogen, cre­atinine, uric acid, and lactate dehydrogenase were increased, while total protein and triglycerides were decreased. The mean concentration of $NO_{x}(NO_{2}^{-}/NO_{3}^{-})$ in the serum of welders and the control group was $35.97{\pm}2.85\;and\;55.40{\pm}5.81\;{\mu}mol/L,$ respectively. The difference was significant (p < 0.05), although $NO_{2}^{-}$ was not detected in the serum.

Biochemical Changes during Embryonic Diapause in Domestic Silkworm, Bombyx mori L. (Lepidoptera: Bombycidae)

  • Singh, Tribhuwan;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • v.5 no.1
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    • pp.1-12
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    • 2002
  • Ecophysiologically diapause represents a syndrome of physiological and biochemical characteristics, all of which ensure survival during a long period of dormancy. Since, silkworm enters diapause as embryo at the early embryonic stage, the duration of egg life depends on the duration of embryonic diapause. The nature of diapause in silkworm, Bombyx mori, is primarily determined by genetic characters and endocrinologicnl mechanisms, mediated by environmental factors such as temperature and photoperiod. Hibernating potency value besides nucleic acid and carbohydrate metabolism, production and utilization of sorbitol are also equally responsible for induction, initiation, determination, maintenance and termination of diapause. Embryonic diapause in Bombyx moir, induced by active secretion of sub-oesophageal ganglion is attributed to hormonal system and metabolic adjustment, which serves to bring about a new physiological state. Metabolic conversion of trehalose to glycogen at induction, glycogen to sorbitol at initiation and sorbitol to glycogen at termination of diapause is correlated and in each metabolic shift a key enzyme becomes active in response to hormonal and environmental stimulation. An attempt has been made in this review article to discuss briefly the nature of embryonic diapause, influence of various factors on diapause nature, hormonal mechanism of diapause besides biochemical composition of egg, nucleic acid and carbohydrate metabolism, production and utilization of sorbitol in relation to induction, determination, maintenance, initiation and termination of diapause in the silkworm, Bombyx mori.

Anthropometric and Biochemical Indicators and Related Factors for the Community Dwelling Elderly Living Alone (지역사회 거주 독거 여자 노인의 신체 계측치와 생화학적 지표 및 관련 인자에 관한 연구)

  • 박진경;손숙미
    • Korean Journal of Community Nutrition
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    • v.8 no.5
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    • pp.726-735
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    • 2003
  • In this study, anthropometric and biochemical indicators and related factors for community dwelling elderly living alone (ELA). as well as for elderly not living alone (ENLA) were explored. The subjects were 140 elderly females (70 living alone, 70 not living alone) residing in Bucheon. Anthropometric measurements revealed significant differences between the two groups (ELA/ENLA) for height, weight, BMI, triceps skinfold thickness, suprailiac skinfold thickness, subscapular skinfold thickness, and body fat percentage. The ELA showed significantly lower data for most of the anthropometric indices, except PIBW. Biochemical indicators of iron status (hemoglobin, serum iron, transferrin saturation) were significantly lower for the ELA, whereas the total serum cholesterol, LDL-C, LDL-C/HDL-C, for the ELA were significantly higher. The prevalence of hypercholesterolemia (240 mg%) was 30%. The latter three are not in accordance with general malnutrition among the ELA. The hemoglobin of the ELA was positively correlated with energy, fat, iron and cholesterol intake, but negatively correlated with height. The serum cholesterol of the ELA was Positively associated with most of their nutrient intake.