• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2000년도 추계학술대회 논문집
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• pp.91-97
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• 2000

The conventional model did not take momentum conservation into consideration when the electron absorbs and emits the photons. II-ray provides momentum conservations on any directions of the entering photons, and also the electrons have radial momentum conservations and fully elastic bouncing between two atoms, in the new atom model. Conventional atom model must be criticized on the following four points. (1) Natural motions between positive and negative entities are not circular motions but linear going and returning ones, for examples sexual motion, tidal motion, day and night etc. Because the radius of hydrogen atom's electron orbit is the order of 10$^{-11}$ m and the radia of the nucleons in the nucleus are the order of 10$^{-l4}$m and then the converging n-gamma rays to the nucleus have so great circular momentum, the electron can not have a circular motion. We can say without doubt that any elementary mass particle can have only linear motion because of the n-rays' hindrances, near the nucleus. (2) Potential energy generation was neglected when electron changes its orbit from outer one to inner one. The h v is the kinetic energy of the photo-electron. The total energy difference between orbits comprises kinetic and potential energies. (3) The structure of the space must be taken into consideration because the properties of the electron do not change during the transition from outer orbit to inner one even though it produces photon. (4) Total energy conservation law applies to the energy flow between mind and matter because we daily experiences a interconnection between mind and body. An understanding of the mechanisms responsible for the control of normal proliferation and differentiation of the various cell types which make up the human body will undoubtedly allow a greater insight into the abnormal growth of cells, A large body of biochemical evidence was eventually used to generate a receptor model with an external ligand binding domain linked through a single trans-membrane domain to the cytoplasmic tyrosine kinase and autophosphory-lation domains. The ligand induced conformational change in the external domain generates either a push-pull or rotational signal which is transduced from the outside to the inside of cell.l.ell.

• 대한임상검사과학회지
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• 제48권2호
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• pp.137-143
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• 2016

본 연구는 22명의 남자 아마추어 선수를 대상으로 100 km 울트라 마라톤에서의 전해질 대사 반응의 안전성을 평가하기 위해 실시하였다. 대상자의 평균 연령은 $50.91{\pm}4.77$세, $VO_2max$는 $48.19{\pm}6.43mL/kg/min$, 그리고 평균 경기 완주시간은 $829.64{\pm}89.31$분이었다. 혈액검사에 포함된 전해질 지표로는 칼슘, 무기인, 마그네슘, 소디움, 포타슘, 염소, 총이산화탄소, 음이온 차이, 혈장량 변화와 삼투압 농도를 경기 전, 50 km 지점, 경기 종료 직후 측정하였다. 본 연구결과 소디움 농도는 경기 전보다 50 km 지점에서 감소하였고 50 km 지점보다 100 km 지점에서 감소하였으나, 고나트륨혈증 및 저나트륨혈증은 나타나지 않았다. 100 km 울트라 마라톤 경기에서 다른 모든 전해질 지표들의 거리별 변화는 참고범위 내에서 이루어졌으며, 혈장량 변화는 나타나지 않았다. 결론적으로 아마추어 지구력 선수들의 전해질 대사에 있어서 경기중 통계적인 차이는 있었으나 임상적으로 의미 있는 삼투압 농도와 전해질의 변화는 나타나지 않았으며 안전한 경기로 나타났다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.195-195
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• 2012

Recently, graphene based solution-gated field-effect transistors (SGFETs) have been received a great attention in biochemical sensing applications. Graphene and reduced graphene oxide (RGO) possess various advantages such as high sensitivity, low detection limit, label-free electrical detection, and ease of fabrication due to their 2D nature and large sensing area compared to 1D nanomaterials- based nanobiosensors. Therefore, graphene or RGO -based SGFET is a good potential candidate for sensitive detection of protons (H+ ions) which can be applied as the transducer in various enzymatic or cell-based biosensing applications. However, reports on detection of H+ ions using graphene or RGO based SGFETs have been still limited. According to recent reports, clean graphene grown by CVD or exfoliation is electrochemically insensitive to changes of H+ concentration in solution because its surface does not have terminal functional groups that can sense the chemical potential change induced by varying surface charges of H+ on CVD graphene surface. In this work, we used RGO -SGFETs having oxygen-containing functional groups such as hydroxyl (OH) groups that effectively interact with H+ ions for expectation of increasing pH sensitivity. Additionally, we also investigate RGO based SGFETs for bio-sensing applications. Hydroloytic enzymes were introduced for sensing of biomolecular interaction on the surface of RGO -SGFET in which enzyme and substrate are acetylcholinesterase (AchE) and acetylcholine (Ach), respectively. The increase in H+ generated through enzymatic reaction of hydrolysis of Ach by AchE immobilized on RGO channel in SGFET could be monitored by the change in the drain-source current (Ids).

• 공학교육연구
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• 제8권4호
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• pp.31-39
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• 2005

사회는 매우 빨리 변화하고 있으나 변화의 핵심 인력과 기술을 제공해야하는 이공계대학의 교육과정은 이러한 변화의 속도를 따라가지 못하고 있다. 사회에서는 한 명이 수만 명을 먹여 살릴 수 있는 소위 gold color engineer 를 요구하고 있으나 대학의 반응은 아직까지 미진하다. 따라서 이런 사회의 빠른 변화에 대응하여 이공계교육이 적절히 변화할 수 있는 교육시스템의 구축이 매우 필요하다. 본 논문에서는 이를 위하여 이공계 대학교육과정의 문제점을 분석하고 그 개선방안을 논하고자 한다. 이공계 교육 내용에 대한 공급자와 수요자의 차이를 분석하고 이를 제고하기 위하여 새로운 교육체계를 제시하였다. 직업기초능력에 대한 설문을 실시하였고 국내외 이공계 교육 현황과 최근 국내 이공계 신입생의 과목이수 내용 등을 조사하였다. 또한 교육과정 개선을 위한 국가의 지원 방안을 제시하였다.

• 사상체질의학회지
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• 제24권3호
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• pp.69-79
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• 2012

Objectives This study was performed to research the biological change after walking program in forest according to Sasang constitution. Methods Twenty four applicants are involved in this study. They were classified into three groups(Soyangin, Taeeumin, Soeumin) by QSCC II and divided into two groups(roadway, forest path) by place. And then they participated in walking program on March 31 in 2012. We performed before and after measurements, including active oxygen, biochemical test(BC), and stress hormones. Results Cortisol decreased in the entire group after walking program, which means the effect of relaxation. Glucose reduced in Soyangin group while increased in Taeeumin and Soeumin group after the program. There was no correlation in the test results between Sasang constitution and walking place. Conclusions Walking program has shown most efficacy in relaxation. However a single positive result within this study should be carefully interpreted. In the future, well-designed studies for Sasang constitutional walking program are needed.

• 한국지반공학회논문집
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• 제29권2호
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• pp.23-34
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• 2013

식물의 추출물로 제조할 수 있는 유기산 재료는 포설 시 지중 속에서 미생물의 증식을 유도하며, 미생물에 의해 지반에서 압밀을 가속화시키고 빠르게 간극수압을 소산시킨다. 추가적으로 일부 미생물에 의해 탄산칼슘을 생성시켜 공극을 채워 강도를 증대시키거나 투수성을 감소시킬 수 있다. 따라서, 본 연구에서는 유기산 재료의 지반개량 메커니즘 규명을 위하여 화강풍화토, 라테라이트성 적토에 유기산 재료 혼합 전 후의 강도와 투수시험을 실시하였으며, SEM, XRD로부터 원인을 규명하였다. 유기산 재료 혼합 후 재령 96일에서 강도는 약 1.5~2.5배 증가하였으며, 투수계수는 72.9~93.1%의 감소율을 보였다. SEM으로부터 흙 입자의 구조가 변하거나 공극이 감소한 것을 관찰하여 강도증대, 투수감소의 원인을 규명할 수 있었으며, XRD로부터 탄산칼슘의 생성도 고결화의 주된 요인이라고 결론내릴 수 있었다. 이에 본 유기산 재료는 친환경적으로 지반을 개량할 수 있는 공법으로 활용될 수 있을 것으로 보인다.

• 환경생물
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• 제22권3호
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• pp.387-393
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• 2004

사료를 통한 benzo(a)pyrene이 조피볼락, Sebastes schlegeli의 lipid peroxidation (LPO), superoxide dismutase(SOD)활성과 간 조직의 병변 현상에 미치는 영향을 연구하기위해 0 (대조구), 0.5, 1.0, 1.5, 2.0 mg $kg^{-1}$ 농도의 사료를 조제하여 30일간 급이하였다. LPO는 2.0mg kg$^{-1}$농도구에서 전 실험기간 동안 유의적으로 증가하였고, SOD 활성도 2.0 mg $kg^{-1}$ 농도구에서 30일째에 유의적으로 증가하였다. 간 조직 검경시 10일째에 1.0mg $kg^{-1}$ 이상의 농도구에서 세포비대가 나타났고, 같은 농도에서 periodic acid-Schiff (PAS) 염색시 양성으로 나타나는 granule이 30일째에 나타났고, 2.0mg $kg^{-1}$ 농도구에서는 20일째부터 관찰되었다. 그리고, 30일째 2.0mg $kg^{-1}$ 농도구의 일부 어체에서는 간 세포의 괴사가 관찰되었다.

• Journal of Life Science
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• 제10권2호
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• pp.39-44
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• 2000

Trichostatin A (TSA) is a Streptomyces product, which inhibits the enzyme activity of histone deacetylase. It is also known as an inducer of apoptosis in several human cancer cell lines. In this study, we investigated the mechanism of apoptosis induced by TSA in MDA-MB-231 human breast carcinoma cells. The cytotoxicity of TSA on MDA-MB-231 cells was assessed by MTT assay. The cell viability was decreased dose-dependently and the IC\ulcorner value was about 100 ng/ml after 48 h treatment with TSA. Morphological change and DNA ladder formation, the biochemical hallmarks of apoptotic cell death, were observed after treatment of TSA in a concentration-dependent manner, which was accompanied with cleavage of poly(ADP-ribose) polymerase and $\beta$-catenin, and activation of caspase-3. TSA treatment up-regulated the expression of a cyclin-dependent kinase inhibitor p21 (Wafl/Cip1) protein, a key regulatory protein of the cell cycle. However, there is no detectable change of both Bcl-2 and Bax expressions. These results demonstrated that TSA might inhibit cell growth through apoptosis in human breast carcinoma MDA-MB-231 cells.

• Membrane and Water Treatment
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• 제10권5호
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• pp.339-352
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• 2019

Long term water quality change was analyzed to evaluate the effect of the Total Maximum Daily Load (TMDL) policy. A trend analysis was performed for biochemical oxygen demand (BOD) and total phosphorus (TP) concentrations data monitored at the outlets of the total 41 TMDL unit watersheds of the Nakdong River in the Republic of Korea. Because water quality data do not usually follow a normal distribution, a nonparametric statistical trend analysis method was used. The monthly mean values of BOD and TP for the period between 2004 and 2015 were analyzed by the seasonal Mann-Kendall test and the locally weighted scatterplot smoother (LOWESS). The TMDL policy effect on the water quality change of each unit watershed was analyzed together with the results of the trend analysis. From the seasonal Mann-Kendall test results, it was found that for BOD, 7.8 % of the 41 points showed downward trends, 26.8 % and the rest 65.9% showed upward and no trends. For TP, 51.2% showed no trends and the rest 48.8% showed downward trends. From the LOWESS analysis results, TP began to decrease in most of the unit watersheds from mid-2010s when intensive chemical treatment processes were introduced to existing wastewater treatment plants. Overall, for BOD, relatively more points were improved in the main stream compared to the points of the tributaries although overall trends were mostly no trend or upward. For TP, about half of the points were improved and the rest showed no trends.

• 한국식품조리과학회지
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• 제12권4호
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• pp.562-570
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• 1996

A weight control program has been prescribed to investigate its effects on weight reduction of obese adults. The prescribed weight control program has been followed by 4 overweight adults and fad diets has been followed by 6 ovenveight adults for 3 to 7 months. The prescribed weight control program was basically the low calorie diet (1,500-1,800 kcal per day) and nutrition education was applied to enhance its effects. Fad diets were chosen among the fashionable diets and they were "apple diet" , "yogurt diet" and "Lee Hijae diet" Anthropometric measurements, biochemical parameters, and percent of body fat were measured after the respective period of weight control program. Body weight was significantly (p<0.01) reduced and the rate of obesity was also significantly lowered with the prescribed weight control program while the body weight and rate of obesity were not changed with the fad diets. Weight loss from the prescribed weight control program also led to the change of total cholesterol levels while LDL-cholesterol, HDL-cholesterol, triglyceride were not significantly changed. Nutrition education and counseling of the weight control subjects induced more weight loss and better food behavior. It is suggested that a weight loss program should be based on the low calorie diet with the well-planned nutrition education The fashionable diets were attractive for a short time period in weight reduction but the rapid weight gain was noticed right after the diets ceased.