• 제목/요약/키워드: Bio-nano

검색결과 870건 처리시간 0.022초

Dinitroethylenediamine Palladium(II)의 합성 및 결정구조 연구 (Synthesis and Structure Dinitroethylenediamine Palladium(II))

  • 남궁해
    • 한국결정학회지
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    • 제15권2호
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    • pp.74-77
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    • 2004
  • Dinitroethylenediaminepalladium(II), $Pd(C_2H_8N_2)\;(NO_2)_2$의 결정구조는 a=7.425(3), b=8.480(4), c=11.885(2)${\AA}$, 사방정계(Orthorhombic), 공간군 $A2_1ma$, 공간군 번호 36이며, Z=4, V=748.3(4)${\AA}^3,\;D_c=2.295\;gcm^{-3},\;{\mu}=2.457mm^{-1}$이었다. 구조분석은 중금속법으로 풀었으며, 최소 자승법으로 정밀화하였고, 최종 신뢰도 값들은 377개의 회절반점에 대하여 $(R_1=0.0306,\;R_w=0.0802,\;R_{all}=0.0320,\;S=1.166)$이었다. 최종 분석한 착염의 결합거리와 각들은 기존에 알려진 해당 자료들에 상응하였다. 착염의 구조는 Reiset's salt type 유사체와 같은 일차원 구조로써 c축을 따라서, Pd-Pd 거리가 3.762(2) $(\AA)$이고, 각 $161.41(5)^{\circ}$인 지그재그 사슬구조를 형성하고 있다. 사슬내에서나 사슬간에는 질소와 산소사이에 각각 3.05(1)과 3.15(1) ${\AA}$인 수소결합으로 연결되어 있다.

다시마와 다시마 요구르트의 변비해소 효과 (Effects of Sea Tangle Extract and Sea Tangle Yogurt on Constipation Relief)

  • 김현진;김순임;한영실
    • 한국식품조리과학회지
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    • 제24권1호
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    • pp.59-67
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    • 2008
  • In an effort to make a functional and stable yogurt, this study investigated the improvement effects of sea tangle extract and sea tangle yogurt on intestinal function. The intestinal improvement effect of the extract was measured by the charcoal meal transit method, employing Balb/C mice. And constipation relief was compared utilizing the loperamide-induced constipation method, employing SD rats. Charcoal meal transit was remarkably increased in the mice receiving sea tangle extract as compared to the controls. The constipation relief effects of the sea tangle and sea tangle yogurt were evaluated by measuring fecal amounts in the rats after adding them to water. The fecal contents increased remarkably in the sea tangle administered rat groups as compared to the control group. In addition, different yogurt samples were used to evaluate the characteristics of the sea tangle yogurt. During storage, pH slightly decreased in the yogurt with sea tangle as well as without. At the same time, acidity slowly increased as the storage duration increased. As time elapsed, the amounts of viable cells increased in both yogurts (with and without sea tangle). In the sensory evaluation, significant differences were shown between the sea tangle yogurt and the control for color, flavor, sweetness, and overall quality. Overall, based on the combined results of the intestinal function effects and sensory evaluation, the 0.25% sea tangle yogurt proved to be superior.

Reduction of Body Weight by Capsaicin is Associated with Inhibition of Glycerol-3-Phosphate Dehydrogenase Activity and Stimulation of Uncoupling Protein 2 mRNA Expression in Diet-induced Obese Rats

  • Ann, Ji-Young;Lee, Mak-Soon;Joo, Hyun-Jin;Kim, Chong-Tai;Kim, Yang-Ha
    • Preventive Nutrition and Food Science
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    • 제16권3호
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    • pp.210-216
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    • 2011
  • Capsaicin is a pungent component of red pepper, which is widely consumed as food adjuncts. The present study was performed to investigate anti-obesity effects of capsaicin in diet-induced obese rats. Male Sprague-Dawley rats (n=14) were fed with a high-fat diet (Control) or high-fat diet containing 0.016% capsaicin (w/w) (Capsaicin) for 8 weeks. The final body weight and the mass of white adipose tissue were significantly lower in capsaicin supplemented group compared to control. Dietary capsaicin ameliorated lipid profiles with decrease in the plasma concentrations of triglycerides and total cholesterol, and decrease in the levels of total lipids and triglycerides in the liver. Activity of glycerol-3-phosphate dehydrogenase (GPDH), an indicator of triglyceride biosynthesis in white adipose tissue, decreased by 35% in the group supplemented with capsaicin. However, consumption of capsaicin increased the expression of uncoupling protein 2 (UCP2) in white adipose tissue, which is related to energy consumption. Our data suggests that capsaicin may reduce body weight and fat accumulation in high fat diet-induced obese rats. These effects may be mediated, at least partially, by the upregulation of UCP2 gene expression and its ability to inhibit GPDH activity.

표면 솔-젤 반응을 활용한 마이크로미터 크기의 비구형상 공동 입자의 제조 (Fabrication of Hollow Micro-particles with Nonspherical Shapes by Surface Sol-gel Reaction)

  • 조영상;전석진;이기라
    • Korean Chemical Engineering Research
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    • 제45권6호
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    • pp.611-618
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    • 2007
  • 아민기로 코팅된 단분산 폴리스티렌 입자를 제조한 뒤 톨루엔-물로 구성된 유중수 액적(oil-in-water emulsion) 내부에서 입자를 자기 조립(self-assembly)시켜 다양한 다면체(polyhedra) 구조의 콜로이드 클러스터(colloidal cluster)를 제조하였다. 콜로이드 클러스터의 표면에서 솔-젤(sol-gel) 반응을 유발한 뒤 표면이 실리카로 코팅된 복합(composite) 콜로이드 클러스터를 제조할 수 있었고 이를 주형(template)으로 활용하여 고온 소성에 의해 내부의 폴리스티렌 입자를 제거하고 마이크로미터 크기의 다양한 구조의 비구형상 공동 입자(hollow particle)를 제조하였다. 밀도구배원심분리법 (density gradient centrifugation)에 의해 폴리스티렌 구성 입자의 수와 구조가 균일한 콜로이드 클러스터를 제조할 수 있었으며 표면 솔-젤 반응에 의해 비구형상 구조의 공동 입자를 제조하였다.

캡슐 내시경의 기술적 특징과 동향 (Technical Characteristics and Trends of Capsule Endoscope)

  • 김기윤;원경훈;최형진
    • 한국통신학회논문지
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    • 제37권4C호
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    • pp.329-337
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    • 2012
  • 캡슐 내시경은 인체 내부의 소화기관 병변을 조사할 수 있는 캡슐 모양의 전자장치로서 인체 내에 케이블을 삽입하는 기존 푸시 타입(push-type)내시경과는 달리 환자에게 공포와 고통을 주지 않는 시술로 인식되고 있어, 최근 환자와 의사 모두에게 큰 관심을 끌고 있다. 이 기술은 바이오 기술(BT), 정보통신 기술(IT), 나노 기술(NT) 등의 성숙과 융합으로 2000년에 들어와 처음으로 가능하게 되었으며, LED를 포함한 광학계와 이미지 센서, 통신 모듈, 파워 모듈 등으로 구성되어 있다. 캡슐 내시경은 첨단 기술의 총체로 유비쿼터스 시대에 다양한 기술 분야의 핵심 기술을 필요로 한다. 따라서 본 논문에서는 캡슐 내시경의 구성에 관해 소개하고, 현재 데이터 전송을 위해 사용되고 있는 대표적인 RF 무선 통신 방식 및 인체 통신 시스템 방식에 대해 비교하였다. 아울러 현재 상용된 캡슐 내시경의 사양을 비교 분석하고, 미래의 캡슐 내시경의 진화 방향과 기술적 도전 과제를 제시하였다.

유독 이온성 액체의 장기 노출에 대한 Shewanella oneidensis MR-1의 반응: MR-1과 순응된 균주 SH-1의 비교 연구 (Response of Shewanella oneidensis MR-1 to Longterm Exposure with Toxic Ionic Liquid: Comparative Studies on MR-1 and SH-1, an Acclimated Strain)

  • 한상현;강창호;곽대영;하성호;구윤모;소재성
    • KSBB Journal
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    • 제28권2호
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    • pp.146-150
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    • 2013
  • In this study, we investigated the effects of longterm exposure to ionic liquid (IL) on Shewanella oneidensis MR-1 (MR-1). MR1 was acclimated through repeated exposure to IL. The acclimated strain was named as S. oneidensis SH-1 (SH-1) and compared with MR-1 in various aspects including morphology, cell surface hydrophobicity (CSH), motility, and fatty acid. Compared to the MR-1, SH-1 showed elongated cell shape on scanning electron microscopy. Upon exposure to IL, hydrophobicity of SH-1 (28.2%) was higher that of MR-1 (3.3%). In contrast, motility of SH-1 (7 mm) was lower than that also of MR-1 (22 mm), and branched chain fatty acid of SH-1 was lower than that of MR-1, 27.6% and 41.1%, respectively.

외부챔버와 유연한 튜브로 연결된 LCD 패널 검사기 방진용 공기 스프링의 열 및 동적 연성거동에 대한 연구: PART I, 이론적 모델링 (Study on the Thermal and Dynamic Behaviors of Air Spring for vibration isolation of LCD panel inspecting machine connected with an External Chamber through a flexible tube: PART I, Theoretical Modeling)

  • 석종원;이주홍;김필기
    • 반도체디스플레이기술학회지
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    • 제10권1호
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    • pp.33-41
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    • 2011
  • Due to the recent quantum leaps forward in bio-, nano-, and information-technologies (BT, NT and IT), the precisionization and miniaturization of mechanical and electrical components are in high demand. In particular, the ITrelated equipments that take a great part in our domestic industry are in the area requiring high precision technologies. As a consequence, the researches on the development vibration isolation systems that diminish external disturbance or internal vibration are highly required. Among the components comprising the vibration isolation system, air spring has become on a focal point for the researchers due to its merits. This air spring is able to support heavy loads, keep a low natural frequency despite of having a lower value of stiffness, and control the performance of vibration isolation. However, sometimes the sole use of air spring is in demand due to some economic reasons. Under this circumstance, the damping effect of sole air spring may not enough to reduce sufficient amount of vibration. In this study, the air spring mount system connecting with an external chamber is proposed to increase or control the damping effect. To investigate its damping mechanism, the thermal and dynamic behaviors of the system is examined through a theoretical modeling approach in this part of research. In this approach, thermomechanical and Helmholtz resonator type models are to be employed for the air spring/external chambers and connecting tube system, respectively. The frequency response functions (FRFs) derived from the modeling effort are evaluated with physical parametric values and the effects of connecting tube length on these FRFs are identified through computer simulations.

Yeast Associated with the Ambrosia Beetle, Platypus koryoensis, the Pest of Oak Trees in Korea

  • Yun, Yeo Hong;Suh, Dong Yeon;Yoo, Hun Dal;Oh, Man Hwan;Kim, Seong Hwan
    • Mycobiology
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    • 제43권4호
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    • pp.458-466
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    • 2015
  • Oak tree death caused by symbiosis of an ambrosia beetle, Platypus koryoensis, and an ophiostomatoid filamentous fungus, Raffaelea quercus-mongolicae, has been a nationwide problem in Korea since 2004. In this study, we surveyed the yeast species associated with P. koryoensis to better understand the diversity of fungal associates of the beetle pest. In 2009, a total of 195 yeast isolates were sampled from larvae and adult beetles (female and male) of P. koryoensis in Cheonan, Goyang, and Paju; 8 species were identified by based on their morphological, biochemical and molecular analyses. Meyerozyma guilliermondii and Candida kashinagacola were found to be the two dominant species. Among the 8 species, Candida homilentoma was a newly recorded yeast species in Korea, and thus, its mycological characteristics were described. The P. koryoensis symbiont R. quercusmongolicae did not show extracelluar CM-cellulase, xylanase and avicelase activity that are responsible for degradation of wood structure; however, C. kashinagacola and M. guilliermondii did show the three extracellular enzymatic activities. Extracelluar CM-cellulase activity was also found in Ambrosiozyma sp., C. homilentoma, C. kashinagacola, and Candida sp. Extracelluar pectinase activity was detected in Ambrosiozyma sp., C. homilentoma, Candida sp., and M. guilliermondii. All the 8 yeast species displayed compatible relationships with R. quercus-mongolicae when they were co-cultivated on yeast extract-malt extract plates. Overall, our results demonstrated that P. koryoensis carries the yeast species as a symbiotic fungal associate. This is first report of yeast diversity associated with P. koryoensis.

천연 향균물질 함유 나노섬유의 제조 및 특성분석 (Preparation and Characterization of Electrospun Nanofibers Containing Natural Antimicrobials)

  • 김영진;김상남;권오경;박미란;강인규;이세근
    • 폴리머
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    • 제33권4호
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    • pp.307-312
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    • 2009
  • 전기방사법으로 식물성 폴리페놀을 함유하는 PHBV 나노섬유를 제조하였으며, 얻어진 나노섬유의 평균직경은 340-450 nm였다. 폴리페놀의 첨가에 의해 나노섬유의 직경이 증가하였으며 폴리페놀의 첨가량도 나노섬유의 직경 변화에 영향을 미쳤다. 이는 PHBV와 폴리페놀 사이의 수소결합에 기인하는 것으로 확인되었다. 제조된 나노섬유를 이용한 ATR-FTIR 분석 결과 PHBV와 폴리페놀 사이에 수소결합이 존재하는 것을 확인할 수 있었고, XRD 분석 결과 폴리페놀의 첨가에 의해 PHBV 나노섬유의 결정성이 높아졌다. 이들 폴리페놀을 함유하는 나노섬유는 우수한 항균특성을 보였다.

Cyclic olefin copolymer (COC) 폴리머 프리즘을 사용한 광섬유 기반 표면 플라즈몬 공명 (SPR) 바이오 센서 (A fiber optic surface plasmon resonance (SPR) sensorusing cyclic olefin copolymer (COC) polymer prism)

  • 윤성식;이수현;안종혁;이종현
    • 센서학회지
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    • 제17권5호
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    • pp.369-374
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    • 2008
  • A novel fiber optic surface plasmon resonance (SPR) sensor using cyclic olefin copolymer (COC) prism with the spectral modulation is presented. The SPR sensor chip is fabricated using the SU-8 photolithography, Ni-electroplating and COC injection molding process. The sidewall of the COC prism is partially deposited with Au/Cr (45/2.nm thickness) by e-beam evaporator, and the thermal bonding process is conducted for micro fluidic channels and optical fibers alignment. The SPR spectrum for a phosphate buffered saline (0.1.M PBS, pH.7.2) solution shows a distinctive dip at 1300.nm wavelength, which shifts toward longer wavelength with respect to the bovine serum albumin (BSA)concentrations. The sensitivity of the wavelength shift is $1.16\;nm{\cdot}{\mu}g^{-1}{\cdot}{\mu}l^{-1}$. From the wavelength of SPR dips, the refractive indices (RI) of the BSA solutions can be theoretically calculated using Kretchmann configuration, and the change rate of the RI was found to be $2.3{\times}10^{-5}RI{\cdot}{\mu}g^{-1}{\cdot}l^{-1}$. The realized fiber optic SPR sensor with a COC prism has clearly shown the feasibility of a new disposable, low cost and miniaturized SPR biosensor for biochemical molecular analyses.