• Progress in Medical Physics
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• v.28 no.3
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• pp.83-91
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• 2017

In this work, we investigated the recently proposed phase-contrast x-ray imaging (PCXI) technique, the so-called single grid-based PCXI, which has great simplicity and minimal requirements on the setup alignment. It allows for imaging of smaller features and variations in the examined sample than conventional attenuation-based x-ray imaging with lower x-ray dose. We performed a systematic simulation using a simulation platform developed by us to investigate the image characteristics. We also performed a preliminary PCXI experiment using an established a table-top setup to demonstrate the performance of the simulation platform. The system consists of an x-ray tube ($50kV_p$, 5 mAs), a focused-linear grid (200-lines/inch), and a flat-panel detector ($48-{\mu}m$ pixel size). According to our results, the simulated contrast of phase images was much enhanced, compared to that of the absorption images. The scattering length scale estimated for a given simulation condition was about 117 nm. It was very similar, at least qualitatively, to the experimental contrast, which demonstrates the performance of the simulation platform. We also found that the level of the phase gradient of oriented structures strongly depended on the orientation of the structure relative to that of linear grids.

• Journal of Sensor Science and Technology
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• v.25 no.2
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• pp.131-137
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• 2016

In this study, a multilevel visible light communication (VLC) system based on resistor ladder circuit is designed to transmit medical data. VLC technology is being considered as an alternative wireless communication due to various advantages such as ubiquity, license free operation, low energy consumption, and no radio frequency (RF) radiation characteristics. With VLC even in places where traditional RF communication (e.g., Wi-Fi) is forbidden, significant bio-medical signal including the electrocardiography (ECG) and photoplethysmography (PPG) data can be transmitted. More lives could be saved anywhere by this potential advantage of VLC with a fast emergency response time. A multilevel transmission scheme is adopted to improve the data capacity with keeping simplicity, where data transmission rate can increase by log2m times (m is the number of voltage levels) than that of conventional VLC transmission based on on/off keying. In order to generate multi-amplitudes, resistor ladder circuit, which is a basic principle of digital to analog convertor, is employed, and information is transferred through LED (Light-Emitting Diode) with different voltage level. In the receiver side, multilevel signal is detected by optical receiver including a photo diode. Then, the collected data are analyzed to serve the necessary medical care to the concerned patient.

• Journal of Biomedical Engineering Research
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• v.28 no.3
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• pp.417-422
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• 2007

In this study, we investigated spatio-temporal eye-hand coordination by the "Global effect paradigm", a target-distracter configuration Global effect is observed a variety of visual tasks, for example, during rapid automatic tracking, scanning for target detail, and the comparison of target configurations. Global effect used to investigate eye-hand coordination with a task that presents a target close to a distracter. Eight young subjects participated in the experiments. The experiments consist of using a distracter less eccentric than the targe1 and using a distracter more eccentric than target. Each experiment consist of tasks which are making reference, pointing the target with watching visual stimulation(saccade) and pointing the target. The subject's task was to move towards the target as quickly as possible. We measured the eye movement by using EOG and the hand movement by using NDI Optotrak system. This study shows that eye and hand movement exists for global effect paradigm in spatio-temporal coordination.

• Journal of Biomedical Engineering Research
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• v.29 no.5
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• pp.408-413
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• 2008

Human body has a complete left and right symmetry structure, and the left and right balance by Yin and Yang. When the balance is broken, the left and right Meridian becomes abnormal condition. Acupuncture is a kind of therapy to recover from energy unbalance of the left and right Meridian to a new balance condition. In the study, we observed the electric potential along the stomach meridian (ST) in order to verify the energy consensus phenomenon by transportation of bio-energy between operator and subject during acupuncture. The acupuncture effects on opposite meridian site were investigated by comparing the electric potentials between the right and left ST sites. Meridian electrical potentials (MEPs) between operator and subject were simultaneously generated during the acupuncture and the polarity of MEPs was opposite. The results might imply the bio-energy transportation between operator and subject. In addition, we observed three different patterns of MEPs on both ST sites which might represent the condition of the related meridians because meridians in the body are organically interconnected.

• 전자공학회논문지 IE
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• v.49 no.2
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• pp.58-64
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• 2012

In this paper, we proposed a distributed gateway for ubiquitous healthcare system. We also designed and implemented protocol conversion and processing algorithms to exchange a seamless information, the bio signals between the databases and the receiving devices from ZigBee to gateway and from the gateway to database and network. The distributed gateway system consists of the bio signal acquisition, ZigBee modules, distributed databases, and gateways. The bio signals detected by the ZigBee module are sent to the gateway. The distributed gateway analyzes the data being transferred, sends those to the receiving devices, and lets the authorized personnel access. The proposed system can be utilized in various fields including activity analysis for the elderly, security systems, home network service, and so on.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.11 no.4
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• pp.299-306
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• 2017

The Korean medical device industry has increased dramatically due to various investments in the domestic medical device industry and the introduction of new technologies, but the domestic medical device usage rate in great hospital is still low. In this paper, improvement point for domestic medical device was suggested by domestic medical device usage rate and user and manager's perception survey in great hospitals in Korea. To do this, a survey on the types of medical devices and domestic medical device usage rates were conducted at four national university hospitals in Korea. From this results, the priority survey medical devices were selected. Improvements of Korean medical devices were suggested by failure mode analysis and user awareness surveys for the priority survey medical devices.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.01a
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• pp.299-300
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• 2013

의료시장의 무한경쟁과 의료 경영환경을 극복하기 위한 최선의 방안은 병원 업무의 전산화를 통한 시스템 간의 효율적인 정보교환의 필요성이 대두되고 있다. 또한, 처방전달시스템, 전자의무기록시스템, 검사정보시스템, 의료영상 저장 및 전송시스템 등의 이기종간 의료정보 시스템의 통합 시스템을 구축하여 진료환경을 구축하고 진료의 효율성을 개선해야 할 것이다. 본 논문에서는 업무 시스템 간에 상호 연계가 보장된 표준정보연계체계 구축 및 최적화된 응용시스템 구축으로 환자 서비스 개선과 진료 및 경영 효율을 증대시킨 통합의료정보시스템의 구축방안에 대하여 연구하였다.

• Mycobiology
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• v.49 no.6
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• pp.599-603
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• 2021

CRISPR/Cas9 genome editing systems have been established in a broad range of eukaryotic species. Herein, we report the first method for genetic engineering in pyogo (shiitake) mushrooms (Lentinula edodes) using CRISPR/Cas9. For in vivo expression of guide RNAs (gRNAs) targeting the mating-type gene HD1 (LeA1), we identified an endogenous LeU6 promoter in the L. edodes genome. We constructed a plasmid containing the LeU6 and glyceraldehyde-3-phosphate dehydrogenase (LeGPD) promoters to express the Cas9 protein. Among the eight gRNAs we tested, three successfully disrupted the LeA1 locus. Although the CRISPR-Cas9-induced alleles did not affect mating with compatible monokaryotic strains, disruption of the transcription levels of the downstream genes of LeHD1 and LeHD2 was detected. Based on this result, we present the first report of a simple and powerful genetic manipulation tool using the CRISPR/Cas9 toolbox for the scientifically and industrially important edible mushroom, L. edodes.

• Journal of radiological science and technology
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• v.37 no.2
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• pp.75-84
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• 2014

In this study, we surveyed the current status, satisfaction and demand of radiologic technologist continuing education for 93 radiologic technologists who participated in the continuing education. To understand the current status and general evaluation and to find out the improvement direction, survey was conducted on 3 categories: participation, satisfaction and demand of continuing education. In addition, we analyzed the continuing education implementation status and the management system by collecting related regulations. As a result, the education completion rates of radiologic technologists from 2010 to 2012 were respectively 42.6%, 43.4% and 34.2%; the rates were similar to other medical technician's average education completion rates. According to the survey, in case of participation, the most frequent answer was 'more than five times less than 10 times per year' with 48.4% and in satisfaction section, the most common answer was 'Average(3)' with 34.4%. In demand of continuing education section, 32.8% of the respondents chose 'Clinical skill training in major field'. In the results of this research, continuing education needs to be managed in the direction of helping radiologists improve their personal ability and self development. Furthermore, to meet the demand of radiologists, the quality of continuing education should be improved to satisfy the educatee.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.11
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• pp.1242-1250
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• 2011

Several biomimetic artificial muscles including the electro-active synthetic polymers (SSEBS, PSMI/PVDF, SPEEK/PVDF, SPSE, XSPSE, PVA/SPTES and SPEI), bio-polymers (Bacterial Cellulose and Cellulose Acetate) and nano-composite (SSEBS-CNF, SSEBS-$C_{60}$, Nafion-$C_{60}$ and PHF-SPEI) actuators are introduced in this paper. Also, some applications of the developed biomimetic actuators are explained including biomimetic robots and biomedical active devices. Present results show that the developed electro-active polymer actuators with high-performance bending actuation can be promising smart materials applicable to diverse applications.