• Title/Summary/Keyword: Bio-industry

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Biological Synthesis of Alkyne-terminated Telechelic Recombinant Protein

  • Ayyadurai, Niraikulam;Kim, So-Yeon;Lee, Sun-Gu;Nagasundarapandian, Soundrarajan;Hasneen, Aleya;Paik, Hyun-Jong;An, Seong-Soo;Oh, Eu-Gene
    • Macromolecular Research
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    • v.17 no.6
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    • pp.424-429
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    • 2009
  • In this study, we demonstrate that the biological unnatural amino acid incorporation method can be utilized in vivo to synthesize an alkyne-terminated telechelic protein, Synthesis of terminally-functionalized polymers such as telechelic polymers is recognized to be important, since they can be employed usefully in many areas of biology and material science, such as drug delivery, colloidal dispersion, surface modification, and formation of polymer network. The introduction of alkyne groups into polymeric material is particularly interesting since the alkyne group can be a linker to combine other materials using click chemistry. To synthesize the telechelic recombinant protein, we attempted to incorporate the L-homopropargylglycine into the recombinant GroES fragment by expressing the recombinant gene encoding Met at the codons for both N- and C-terminals of the protein in the Met auxotrophic E. coli via Hpg supplementation. The Hpg incorporation rate was investigated and the incorporation was confirmed by MALDI-TOF analysis of the telcchelic recombinant protein.

The Current Trends and the Prospective View of the Molecular Gastronomy (분자미식학의 현황과 앞으로의 전망)

  • Lee, Eun-Jung;Ahn, Jeong-Suk;Choi, Jeong-Yoon
    • Culinary science and hospitality research
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    • v.14 no.1
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    • pp.56-72
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    • 2008
  • Molecular gastronomy is a science that deconstructs the classic haute cuisine and applies science knowledge and laboratory techniques to create textures and flavors in unusual ways. The term 'Molecular Gastronomy' was introduced in 1988 by French chemist 'Herve This' and Oxford physicist 'Nicholas Kurti'. It has since been adopted by both world culinary establishments and scientists, from 'El Bulli' to 'Harold McGee'. Since most world-top prestigious restaurants and chefs were enthralled by this revolunary culinary movement, molecular gastronomy and molecular cooking have drawn a growing interest of lots of Korean people in the food industry until now. However, Korean foodservice industry is unlikely to be ready to develop this advent-garde culinary movement because molecular gastronomy is still an insufficiently established concept of culinary science and philosophy in Korea. Besides, there are many clumsy abuses of putative and clinically unproven bio-chemical components in kitchens and restaurants in the name of culinary science or culinary arts. Such a careless approach and attitude towards an important exercise like a cooking is highly deplorable. Thus it is still too far early to expect the prospective path of molecular gastronomy in Korea without understanding the core principle of molecular gastronomy and having any cultural support.

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Use of Waste Woods for Developing Environment-friendly Shock-absorbing Materials

  • Kim, Chul-Hwan;Song, Dae-Bin;Lee, Young-Min;Kim, Jae-Ok;Kim, Gyeong-Yun;Shin, Tae-Gi;Park, Chong-Yawl
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2006.06b
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    • pp.475-478
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    • 2006
  • Environment-friendly shock-absorbing materials were made using a vacuum forming method from waste wood collected from local mountains in Korea. The waste wood was pulped by thermomechanical pulping. The TMP cushions showed superior shock-absorbing properties with lower elastic moduli compared to EPS and pulp mold. Even though the TMP cushions made using different suction times had many free voids in their inner fiber structure, their apparent densities were a little higher than EPS and much lower than pulp mold. The addition of cationic starch improved the elastic modulus of the TMP cushions without increasing the apparent density, which was different from surface sizing with starch. The porosity of the TMP cushions was a little greater than EPS and much less than pulp mold. Finally, the TMP cushions have great potential to endure external impacts occurring during goods distribution.

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Antimicrobial Fiber Products Treated with Silica Hybrid Ag Nanoparticles

  • Kim, Hwa-Jung;Park, Hae-Jin;Choi, Seong-Ho;Park, Hae-Jun
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.273-279
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    • 2012
  • Silica hybrid silver nanoparticles showing the strong antimicrobial activity, in which nano-silver is bound to silica molecules, has been synthesized using ${\gamma}-irradiation$ at room temperature. The present study relates to an antimicrobial composition for coating fiber products comprising silica hybrid silver nanoparticles. In this study, we describe antimicrobial fiber products coated with the silica hybrid silver nanoparticles and a method of antimicrobially treating fiber products by coating the fiber products with the silica hybrid silver nanoparticles. The antimicrobial fiber products exhibited excellent antimicrobial effects. In detailed practice, when the present composition comprising nanosized silica-silver was applied to a cloth (fabric) in a concentration of $6.4mg\;yard^{-1}$, the viable cell number decreased to less than 10 cells before and after laundering, resulting in a reduction of 99.9% or greater in the viable cell number. The present composition displays long-lasting potent disinfecting effects on bacteria. Also, we investigated the toxicity of silica hybrid silver nanoparticles in rats. The skin of rats was treated with a 30 ppm nanoparticles solution ($2ml\;Kg^{-1}$) for 8 days. No toxicity was detected in the treatment. These results suggest that the fiber products coated with the silica hybrid silver nanoparticles can be used to inhibit the growth of various microorganisms.

Preparation and Characterization of Microorganism Fermentation Celluose as Hydrogel by Radiation Crosslinking (방사선 가교에 의한 미생물 발효 셀룰로오스 하이드로겔의 제조 및 특성)

  • Lim, Youn-Mook;Park, Jong-Seok;Gwon, Hui-Jeong;Nho, Young-Chang;Kim, Sung-Ho;Choi, Young-Hun;Lee, Sun-Yi;Chong, Moo-Sang
    • Journal of Radiation Industry
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    • v.5 no.2
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    • pp.113-118
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    • 2011
  • Hydrogels from a mixture of poly(N-vinylpyrrolidone) (PVP), ${\kappa}$-carrageenan and microorganism fermentation celluose were prepared by $^{60}Co$ gamma-ray irradiation. PVP and ${\kappa}$-carrageenan were mixed with the different ratios. Microorganism fermentation celluose were added to the mixture of PVP and ${\kappa}$-carrageenan to evaluate the effect of microorganism fermentation celluose on the gel strength. The gel strength of the hydrogel was evaluated for application of a wound dressing. The results showed that gelation and gel strength were increased with increasing the content of the microorganism fermentation celluose.

Preparation and Characterization of Microorganism Fermentation Cellulose as Hydrogel Wound Dressing (미생물 발효 셀룰로오스를 이용한 상처 치료용 하이드로겔의 제조 및 특성)

  • Kim, Mi-Yeong;Lim, Youn-Mook;Lee, Jong-Dae;Song, Sung-Gi;Gwon, Hui-Jeong;Park, Jong-Seok;Nho, Young-Chang;Kim, Sung-Ho;Choi, Young-Hun;Lee, Sun-Yi
    • Journal of Radiation Industry
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    • v.4 no.4
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    • pp.365-372
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    • 2010
  • Irradiation has been recognized as a highly suitable tool to aid in the formation of hydrogel. The radiation process has various advantage, such as easy process control and the lack of necessity for initiators and crosslinker. In this study, the hydrogel containing the citrus fermentation gel for the wound healing were successfully synthesized. The strength of hydrogel was increased as a function of a increasing the concentration of citrus and the irradiation doses. In addition, this hydrogel have been evaluated by the cytotoxicity and animal experiment.

Analyzing the Efficiency of National 6T R&D Projects by Two-stage Network DEA Approach (첨단산업기술(6T) 연구개발사업의 효율성 분석: 2단계 네트워크 DEA 접근의 적용)

  • Nam, Hyundong;Nam, Taewoo
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.44 no.3
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    • pp.248-261
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    • 2021
  • Scientific and technological performances (e.g., patents and publications) made through R&D play a pivotal role for national economic growth. National governments encourage academia-industry cooperation and thereby pursue continuous development of science technology and innovation. Increasing R&D-related investments and manpower are crucial for national industrial development, but evidence of poor performance in business performance, efficiency, and effectiveness has recently been found in Korea. This study evaluates performance efficiency of the 6T sector (Information Technology, Bio Technology, Nano Technology, Space Technology, Environment Technology, Culture Technology), which is considered a high-potential promising industry for the next generation growth and currently occupies two thirds of the national R&D projects. The study measures the relative efficiency of R&D in a comparative perspective by employing the Data Envelopment Analysis (DEA) method. The result reveals overall low efficiency in basic R&D (0.2112), applied R&D (0.2083), development R&D (0.2638), and others (0.0641), confirming that economic performance and efficiency were relatively poor compared to production efficiency. Efficient R&D needs policy makers to create strategies that can increase overall efficiency by improving productivity performance and quality while increasing economic performance.

Design and Implementation of a Mobile-based Sarcopenia Prediction and Monitoring System (모바일 기반의 '근감소증' 예측 및 모니터링 시스템 설계 및 구현)

  • Kang, Hyeonmin;Park, Chaieun;Ju, Minina;Seo, Seokkyo;Jeon, Justin Y.;Kim, Jinwoo
    • Journal of Korea Multimedia Society
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    • v.25 no.3
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    • pp.510-518
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    • 2022
  • This paper confirmed the technical reliability of mobile-based sarcopenia prediction and monitoring system. In implementing the developed system, we designed using only sensors built into a smartphone without a separate external device. The prediction system predicts the possibility of sarcopenia without visiting a hospital by performing the SARC-F survey, the 5-time chair stand test, and the rapid tapping test. The Monitoring system tracks and analyzes the average walking speed in daily life to quickly detect the risk of sarcopenia. Through this, it is possible to rapid detection of undiagnosed risk of undiagnosed sarcopenia and initiate appropriate medical treatment. Through prediction and monitoring system, the user may predict and manage sarcopenia, and the developed system can have a positive effect on reducing medical demand and reducing medical costs. In addition, collected data is useful for the patient-doctor communication. Furthermore, the collected data can be used for learning data of artificial intelligence, contributing to medical artificial intelligence and e-health industry.

The Study on the Review of Domestic Laws for Utilizing Health and Medical Data and of Mediation for Medical Disputes (보건의료데이터 활용을 위한 국내 법률검토 및 의료분쟁에 대한 조정 제도 고찰)

  • Byeon, Seung Hyeok
    • Journal of Arbitration Studies
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    • v.31 no.2
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    • pp.119-135
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    • 2021
  • South Korea has the most advanced technology in the Fourth Industrial Revolution era because of its high-speed Internet commercialization. However, the industry is shrinking due to its various regulations in building and its utilization of personal information as big data. Currently, South Korea's personal data utilization business is in its early stages. In the era of the 4th Industrial Revolution, it is difficult for startups to use data. There are various causes here. Above all, legal regulations to protect personal information are emphasized. This study confirms that transactions of personal medical records through My Data can be made. Moreover, it confirms that there is a need for a mediating role between stakeholders. This study lacks statistical access in the process of performing stakeholder roles. However, personal medical records will be traded safely in the future, and new subjects will enter the market. Furthermore, the domestic bio-industry will develop. Through this study, various problems were derived in establishing Medical MyData in Korea. Moreover, it looks forward to continuing various studies in the health care sector in the future.

A Study on the Statistical Status of By-products from Korean Seafood processing for Utilization of Biomaterials (바이오소재 활용을 위한 국내 수산가공부산물의 통계 현황 연구)

  • Soeon, Ahn;Duckhee, Jang;Do-Hyung, Kang
    • Journal of Marine Bioscience and Biotechnology
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    • v.14 no.2
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    • pp.124-132
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    • 2022
  • By-products from fisheries produced in Korea are of the same industrial material as imported raw materials and are valuable resources for marine bioindustries. Securing raw materials for the mass production of functional materials is one of the main objectives for marine bioindustrial development. The use of fishery by-products as raw materials is anticipated to increase rapidly as the biomarket is growing into a promising industry. In this study, data were acquired from an open-source environment to perform exploratory data analysis, and various visualization methods were used to compare fishery production to the production of marine processed products in the year 2020. This study suggested that the amount of seafood processing, types of processing items, and areas where fishery processing residue is generated, should be able to secure hygienic raw material supply in large quantities. Thus far, it has been found that the Gyeonggi-do and Busan province, where HACCP-certified processing facilities are concentrated, and the local government Seafood Cluster and the Smart Aquaculture Cluster are at the forefront of stable, mass production of raw materials.