• Title/Summary/Keyword: Bio-industry

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Protective effects of red orange (Citrus sinensis [L.] Osbeck [Rutaceae]) extract against UVA-B radiation-induced photoaging in Skh:HR-2 mice

  • Yoon Hee Kim;Cho Young Lim;Jae In Jung ;Tae Young Kim;Eun Ji Kim
    • Nutrition Research and Practice
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    • v.17 no.4
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    • pp.641-659
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    • 2023
  • BACKGROUND/OBJECTIVES: The skin is the outermost organ of the human body and plays a protective role against external environmental damages, such as sunlight and pollution, which affect anti-oxidant defenses and skin inflammation, resulting in erythema or skin reddening, immunosuppression, and epidermal DNA damage. MATERIALS/METHODS: The present study aimed to investigate the potential protective effects of red orange complex H extract (ROC) against ultraviolet (UV)-induced skin photoaging in Skh:HR-2 mice. ROC was orally administered at doses of 20, 40, and 80 mg/kg/day for 13 weeks, along with UV irradiation of the mice for 10 weeks. RESULTS: ROC improved UV-induced skin barrier parameters, including erythema, melanin production, transepidermal water loss, elasticity, and wrinkle formation. Notably, ROC inhibited the mRNA expression of pro-inflammatory cytokines (interleukin 6 and tumor necrosis factor α) and melanogenesis. In addition, ROC recovered the UV-induced decrease in the hyaluronic acid and collagen levels by enhancing genes expression. Furthermore, ROC significantly downregulated the protein and mRNA expression of matrix metalloproteinases responsible for collagen degradation. These protective effects of ROC against photoaging are associated with the suppression of UV-induced phosphorylation of c-Jun NH2-terminal kinase and activator protein 1 activation. CONCLUSIONS: Altogether, our findings suggest that the oral administration of ROC exerts potential protective activities against photoaging in UV-irradiated hairless mice.

Reproductive Biology of the Washington Clam Saxidomus purpuratus in the Coastal Waters of Yeosu, Korea (한국 여수에 서식하는 개조개(Saxidomus purpuratus)의 산란생태)

  • Da Yeon Kang;Seong Yong Moon;Kyung Mi Jung;Gun Wook Baeck
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.57 no.1
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    • pp.53-59
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    • 2024
  • The reproductive biology of the Washington clam Saxidomus purpuratus, from Yeosu, Korea was investigated based on 699 individuals collected from January to December 2022. The sex ratio of this species was not significantly different from a 1:1 (male:female) sex ratio (P>0.05). Monthly changes in gonadosomatic index were analyzed to estimate the spawning season. The reproductive cycle of this species can be divided into the following stages: active (Jan.-Mar.), ripe (Mar.-Nov.), spent (Apr.-Dec.), and degenerative (Jun.-Dec.) stages. The spawning period ranged from March to December with the main periods being from April to June and from September to November. The shell length at 50% female group maturity (SL50) was estimated to be 60.2 mm.

[Review] The Impact of Character Collaboration Product Characteristics on Brand Awareness and Purchase Intention: Focusing on F&B Products

  • Kyung Tae JANG;Senghyeon LEE;Seong-Soo CHA
    • The Korean Journal of Food & Health Convergence
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    • v.10 no.2
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    • pp.1-5
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    • 2024
  • This study aims to investigate the impact of character collaboration product characteristics on brand awareness and purchase intention within the food and beverage (F&B) industry, with a special focus on Generation MZ's growing interest in such products. The methodology involves a comprehensive review of existing literature on character marketing, brand awareness, and consumer purchase intention, supplemented by case studies of successful character collaborations in the F&B sector. The findings reveal that character collaborations significantly impact brand awareness and purchase intentions, particularly among younger consumers like Generation MZ. These collaborations not only rekindle nostalgia but also introduce new and exciting consumer experiences, effectively attracting a wide demographic. The success of character-themed products, from Pokémon bread to Coca-Cola's League of Legends collaboration, underscores the strategy's effectiveness in boosting brand recognition and consumer engagement. The implications of this research are manifold for the F&B industry. Firstly, it highlights the importance of leveraging popular characters to forge emotional connections with consumers. Secondly, it suggests that product development should closely align with consumer preferences and market trends to maximize appeal. Lastly, it positions character collaboration as a strategic marketing tool that not only enhances product sales but also strengthens brand loyalty and facilitates sustained brand growth.

Study of the Annals of Joseon Dynasty for Developing Systematic Conservation Scheme (조선왕조실록의 체계적 보존을 위한 기초 연구)

  • Jung, Sun-Young;Lee, Min-Woo;Jang, Hyeon-Joo;Seo, Yung-Bum
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.45 no.2
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    • pp.1-12
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    • 2013
  • The annals of Joseon Dynasty designated as a national treasure No. 151 and a UNESCO World Memory are among the greatest archives that should be preserved permanently and inherited to future generations through the proven scientific conservation method. The annals of Joseon Dynasty in the custody of the National Archives of Korea as the sole original archive, has been restricted from the direct physical and chemical approaches. In this study, it is to develop a systematic conservation management scheme, based on the conservation state of the annals. Four books from the annals were selected out of 848 books and their moisture contents and optical property profiles were measured through the books. All the defects previously and newly found were pictured in 10~100 magnifications. The wire marks left on the Hanji's of the annals were analyzed. It was found that water damages and paper molds were prevalent in all four annals selected, and it was recommended to conduct more research for the conservation of those damaged areas. It turned out that various qualities of Hanji's were used for the time of publishing the annals because moisture content, optical properties, and wire mark intervals were quite different between papers even within one book.

Experimental Study on Compression Behavior between Multi-layered Corrugated Structure and EPS Packaging Materials (골판지 적층재와 EPS 사이의 압축거동에 대한 실험적 연구)

  • Park, Jong-Min;Choi, Won-Sik;Kim, Jong-Soon
    • Journal of the Korean Society of Industry Convergence
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    • v.23 no.1
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    • pp.83-91
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    • 2020
  • The evaluation of the compression behavior of the cushioning material is of importance to achieve appropriate packaging design. In order to change packaging design from polymeric-based to more eco-friendly cellulose-based nire effectively, comparative study on the compression behavior between these two packaging materials is crucial. In this study, the stress-strain behavior, hysteresis loss, and response characteristics for cyclic loading were analyzed through compression tests on multi-layered corrugated structure (MLCS) and expanded polystyrene (EPS) packaging materials. MLCS produced in Korea is produced by winding a certain number of single-faced corrugated paperboard, and the compression behavior of this material was turned out to be 6 stages: elastic stage, first buckling stage, sub-buckling stage, densification stage, last buckling stage and high densification stage. On the other hand, EPS's compression behavior was in 3 stages: linear elastic stage, collapse plateau, and densification stage. The strain energy per unit volume (strain energy density) of MLCS did not differ depending on the material thickness, but it showed a clear difference depending on the raw material and flute type. Hysteresis loss of MLCS ranged from 0.90 to 0.93, and there were no significant differences in the raw material and flute type. These values were about 5 to 20% greater than the hysteresis of the EPS (about 0.78 to 0.87).

Enhancement of Antioxidant Activities and Whitening Effect of Acer mono Sap Through Nano Encapsulation Processes (고로쇠 수액 나노입자의 항산화 활성 및 미백 효과의 증진)

  • Kim, Ji-Seon;Seo, Yong-Chang;Choi, Woon-Yong;Kim, Hack-Soo;Kim, Bo-Hyeon;Shin, Dae-Hyeon;Yoon, Chang-Soon;Lim, Hye-Won;Ahn, Ju-Hee;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.3
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    • pp.191-197
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    • 2011
  • In this study, we investigated antioxidant activities and whitening effects of Acer mono sap by encapsulation of nanoparticles. Acer mono sap was through ultra high pressure process and then encapsulated by lecithin. Nano-encapsulated The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 89.7% in adding sample (1.0 mg/ml), compared to sap of non-encapsulation. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 47.8%. High inhibitory of tyrosinase was also measured as 85.8% by adding lecithin nano-particle of 1.0 mg/ml. The nano-particles also showed 14.8% of low cytotoxicity against human normal fibroblast cells in adding 1.0 mg/ml of the highest concentration. These results indicate that Acer mono sap may be a source of cosmetic agents capable of improving whitening effect and antioxidant activites.

Comparison on Cosmetic Activities of Acer mono Bark and Sap (고로쇠 나무의 수피와 수액의 향장활성 비교)

  • Seo, Yong-Chang;Kim, Ji-Seon;Choi, Woon-Yong;Cho, Jeong-Sub;Lim, Hye-Won;Yoon, Chang-Soon;Ma, Choong-Je;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.4
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    • pp.264-270
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    • 2011
  • In this study, we investigated the cosmetic application of Acer mono sap through an ultra-high pressure process. Exposing Acer mono sap to a ultra-high pressure process resulted in 90.1% cell viability of human normal fibroblast cells (CCD-986sk) when added at the highest concentration. Acer mono sap also showed the hightest free radical scavenging activity after the ultra high pressure process. The melanogenesis inhibition rate in cloned M-3 cells was 59.0%. Tyrosinase was inhibited at a rate of 87.2% by adding 100% HPAMS. Anti-wrinkle activity was 78.1%. Acer mono sap showed enhanced storage following the ultra high pressure process. These results indicate that Acer mono sap may be a source for functional cosmetic agents capable of improving antioxidant, whitening, and antiwrinkling effects.

Cross-Calibration of Domestic Devices and GE Lunar Prodigy Advance Dual-Energy X-Ray Densitometer Devices for Bone Mineral Measurements (국산 이중에너지 방사선흡수 골밀도 장치와 GE Lunar Prodigy의 교차분석 식 도출에 관한 연구)

  • Kim, Jung-Su;Rho, Young-Hoon;Lee, In-Ju;Kim, Kyoung-Ah;Lee, In-Ja;Kim, Jung-Min
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.27-31
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    • 2017
  • Reliable follow-up of bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) is essential in clinical practice. When there is a difference in the BMD values from DXA systems in the same patient, cross calibration equation is required for the reliable follow-up. Unfortunately, no equation is existed in BMD measure between GE Lunar Prodigy Advance (US, GE Healthcare; LPA) and Osteosys Dexxum T (Korea, Osteosys; ODT) DXA systems. In this study, we evaluate the agreement of BMD values between LPA and ODT and suggest the cross calibration equation using European spine phantom (ESP) with two systems. We performed BMD measurements using ten scans with ESP in each DXA systems. We compared BMD values and calculated cross calibration equation by linear regression analysis. The comparison between the LPA and ODT bone densitometers used the ESP. Compared to the ESP BMD values, ODT underestimated 14.36% and LPA overestimated 12.96%. The average of total BMD measurement values acquired with ODT were 21.44% lower than those from LPA. Cross-calibration equation for LPA and ODT was derived from ESP. We calculated simple cross calibration equation for LPA and ODT DXA systems. Cross-calibration equation is necessary for the reliable follow-up of BMD values in two different systems.

A Study on the Relocation of A New Industry Cluster Firm in the Non-Metropolitan Region: The Case of the Bio-Health Cluster in the Chungcheong Region (비수도권 신산업 클러스터 기업의 역외 이전에 관한 고찰: 충청권 바이오헬스 기업 사례)

  • Bong-Kyung Jeon
    • Journal of the Economic Geographical Society of Korea
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    • v.26 no.3
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    • pp.190-201
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    • 2023
  • This study conducted an in-depth case study of bio-health companies in the Chungcheong region to examine the factors influencing the relocation of new industry cluster firms in non-metropolitan areas. Focusing on the experiences and perceptions of key stakeholders within the cluster, which have been relatively overlooked in previous research, this narrative research explored the factors that lead entrepreneurs who initially founded their businesses in non-metropolitan areas to relocate to metropolitan areas as well as the decision-making process involved. Through interviews with 61 key stakeholders within the Chungcheong cluster, it was observed that entrepreneurs receive various benefits from local stakeholders during the initial stages of entrepreneurship. However, as the company enters a phase of significant growth, matters such as securing specialized talent and market accessibility lead them to contemplate relocating to metropolitan areas. Based on case studies of companies that both remained and relocated in the Chungcheong region, this study examines structural drawbacks within non-metropolitan clusters and provides policy implications.

A study on the intention of companies to utilize fishery by-product s in the marine bio industry (수산부산물에 대한 해양바이오산업 활용 의향 조사 연구)

  • Duckhee Jang;Soeon Ahn;Chulhong Oh
    • Journal of Marine Bioscience and Biotechnology
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    • v.15 no.2
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    • pp.67-81
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    • 2023
  • This study examines a business survey on the utilization of fishery by-products with the aim to assess the feasibility of incorporating these by-products into various industries. The research involved surveying 312 biocompanies across the country and conducting an empirical analysis based on the collected data. South Korea, a leading seafood-producing country with a developed seafood processing industry, provides conditions necessary to utilize seafood by-products as raw materials for the marine bioindustry. Among the surveyed biocompanies, 38.5% expressed their intention to engage in industrial activities involving the use of fishery by-products in the future, indicating a significant level of interest within the bioindustry in utilizing marine and fishery by-products. Companies showed interest in diverse materials, such as scales, fish bones, skin, and kelp holdfast beyond those currently defined under the Fisheries By-products Recycling Promotion Act (officially unnamed, 2021). This suggests a need for improvements in the regulatory framework to accommodate these diverse biomaterials. Furthermore, we propose enhancing the efficiency of fishery by-product utilization by focusing on regional specialization in marine bioindustry. This involves utilizing existing legal framework for upcycling fishery by-products and fostering a regionally specialized marine bioindustry.