• Title/Summary/Keyword: Bio-imaging

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3D Non-Rigid Registration for Abdominal PET-CT and MR Images Using Mutual Information and Independent Component Analysis

  • Lee, Hakjae;Chun, Jaehee;Lee, Kisung;Kim, Kyeong Min
    • IEIE Transactions on Smart Processing and Computing
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    • v.4 no.5
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    • pp.311-317
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    • 2015
  • The aim of this study is to develop a 3D registration algorithm for positron emission tomography/computed tomography (PET/CT) and magnetic resonance (MR) images acquired from independent PET/CT and MR imaging systems. Combined PET/CT images provide anatomic and functional information, and MR images have high resolution for soft tissue. With the registration technique, the strengths of each modality image can be combined to achieve higher performance in diagnosis and radiotherapy planning. The proposed method consists of two stages: normalized mutual information (NMI)-based global matching and independent component analysis (ICA)-based refinement. In global matching, the field of view of the CT and MR images are adjusted to the same size in the preprocessing step. Then, the target image is geometrically transformed, and the similarities between the two images are measured with NMI. The optimization step updates the transformation parameters to efficiently find the best matched parameter set. In the refinement stage, ICA planes from the windowed image slices are extracted and the similarity between the images is measured to determine the transformation parameters of the control points. B-spline. based freeform deformation is performed for the geometric transformation. The results show good agreement between PET/CT and MR images.

Diagnostic accuracy of artificially induced vertical root fractures: a comparison of direct digital periapical images with conventional periapical images

  • Lee Ji-Un;Kwon Ki-Jeong;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.34 no.4
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    • pp.185-190
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    • 2004
  • Purpose: To compare the diagnostic accuracy for the detection of root fractures in CMOS-based digital periapical images with conventional film-based periapical images. Materials and Methods: Sixty extracted single-root human teeth with closed apices were prepared endodontically and divided into two groups; artificially induced vertical root fracture group and control group. All radiographs were obtained using the paralleling technique. The radiographs were examined by 4 observers three times within a 4 week interval. Receiver operating characteristic (ROC) analysis was carried out using data obtained from four observers. Intra- and inter-examiner agreements were computed using kappa analysis. Results: The area under the ROC curve (Az) was used as an indicator of the diagnostic accuracy of the imaging system. Az values were as follows: direct-digital images; 0.93, film-based images; 0.92, and inverted digital images; 0.91. There was no significant difference between imaging modalities (P<0.05). The kappa value of inter-observer agreement was 0.42 (range: 0.28-0.60) and intra-observer agreement was 0.57 (range: 0.44-0.75). Conclusion : There is no statistical difference in diagnostic accuracy for the detection of vertical root fractures between digital periapical images and conventional periapical images. The results indicate that the CMOS sensor is a good image detector for the evaluation of vertical root fractures.

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Brain Hologram Visualization for Diagnosis of Tumors using Graphic Imaging

  • Nam, Jenie;Kim, Young Jae;Lee, Seung Hyun;Kim, Kwang Gi
    • Journal of Multimedia Information System
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    • v.3 no.3
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    • pp.47-52
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    • 2016
  • This research paper examines the usage of graphic imaging in Holographic Projections to further advance the medical field. It highlights the importance and necessity of this technology as well as avant-garde techniques applied in the process of displaying images in digital holography. This paper also discusses the different types of applications for holograms in society today. Different tools were utilized to transfer a set of a cancer patient's brain tumor data into data used to produce a 3D holographic image. This image was produced through the transfer of data from one program to another. Through the use of semi-automatic segmentation through the seed region method, we were able to create a 3D visualization from Computed Tomography (CT) data.

Comparison of MRI findings with clinical symptoms in temporomandibular joint internal derangement (측두하악관절 내장증 환자의 임상증상과 자기공명영상 소견의 비교 연구)

  • Kwon Ki-Jeong
    • Imaging Science in Dentistry
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    • v.35 no.2
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    • pp.69-75
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    • 2005
  • Purpose : To determine the clinical correlation of magnetic resonance imaging (MRI) findings of temporomandibular joint internal derangements. Materials and Methods : The MR images of 150 TMJs in 75 patients were analyzed. The clinical symptoms were pain in the preauricular area and masticatory muscles and TMJ sounds. Results : There was a statistically significant relationship between the MRI diagnoses of different types of disc displacements and clinical findings of pain, clicking, and crepitus. The risk of TMJ pain was increased when the disc displacement without reduction occurred at the same time in combination with the osteoarthrosis and effusion. Conclusion : Regardless of the results, the data indicate that each of these MR imaging variables may not be regarded as the unique and dominant factor in defining TMJ pain occurrence.

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Characteristics of integral imaging microscope using point light source array

  • Lim, Young-Tae;Park, Jae-Hyeung;Kwon, Ki-Chul;Kim, Nam
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.1354-1356
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    • 2009
  • In this paper, we explained characteristics of integral imaging microscope using point light source. To display the bio-medical information, which is captured as a form of the elemental images, using autostereoscopic displays, the characteristics analysis of three-dimensional information is required. For integral imaging microscope using point light source array, the elemental image capturing configuration has to satisfy a specific condition. We explain the condition to capture the elemental images and show the experimental results.

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High Resolution Time Resolved Contrast Enhanced MR Angiography Using k-t FOCUSS (k-t FOCUSS 알고리듬을 이용한 고분해능 4-D MR 혈관 조영 영상 기법)

  • Jung, Hong;Kim, Eung-Yeop;Ye, Jong-Chul
    • Investigative Magnetic Resonance Imaging
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    • v.14 no.1
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    • pp.10-20
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    • 2010
  • Purpose : Recently, the Recon Challenge at the 2009 ISMRM workshop on Data Sampling and Image Reconstruction at Sedona, Arizona was held to evaluate feasibility of highly accelerated acquisition of time resolved contrast enhanced MR angiography. This paper provides the step-by-step description of the winning results of k-t FOCUSS in this competition. Materials and Methods : In previous works, we proved that k-t FOCUSS algorithm successfully solves the compressed sensing problem even for less sparse cardiac cine applications. Therefore, using k-t FOCUSS, very accurate time resolved contrast enhanced MR angiography can be reconstructed. Accelerated radial trajectory data were synthetized from X-ray cerebral angiography images and provided by the organizing committee, and radiologists double blindly evaluated each reconstruction result with respect to the ground-truth data. Results : The reconstructed results at various acceleration factors demonstrate that each components of compressed sensing, such as sparsifying transform and incoherent sampling patterns, etc can have profound effects on the final reconstruction results. Conclusion : From reconstructed results, we see that the compressed sensing dynamic MR imaging algorithm, k-t FOCUSS enables high resolution time resolved contrast enhanced MR angiography.

Non-blinking dendritic crystals from C-dot solution

  • Mewada, Ashmi;Vishwakarma, Ritesh;Patil, Bhushan;Phadke, Chinmay;Kalita, Golap;Sharon, Maheshwar;Sharon, Madhuri
    • Carbon letters
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    • v.16 no.3
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    • pp.211-214
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    • 2015
  • Bio-imaging and drug carriers for delivery have created a huge demand for crystals. Crystals are fascinating materials that have been grown for a long time but obtaining biocompatible fluorescent crystals is a challenging task. We report on the growth of fluorescent crystals using a carbon dot (C-dot) solution by a hydrothermal process. The crystallization pattern of these C-dots exhibited a unique dendritic structure having a feather-like morphology. The growth temperature and pressure were maintained at 60℃ and 200 mmHg, respectively, for crystal growth. A green fluorescence (under UV light) that was observed in the C-dot solution was retained in the crystals formed from the solution. Cytotoxicity studies on Vero cells revealed the crystals to be extremely biocompatible. These fluorescent crystals are extremely well suited for biomedical and optoelectronic applications.

Metastatic gastric adenocarcinoma to the mandible (하악에 전이된 위 선양암종)

  • Lee Ji-Un;Kwon Ki-Jeong;Ahn Hyoung-Suk;Koh Kwang-Joon
    • Imaging Science in Dentistry
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    • v.35 no.3
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    • pp.179-183
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    • 2005
  • Metastatic tumors to the jaw bones are uncommon. The most common metastatic tumors to the jaw bones are the breast, lung and kidney. In the jaw bones, the common location of the lesions is the mandible, and the posterior area of the mandible is more commonly affected. The radiographic appearance is quite variable. In this report, a very rare case of metastatic gastric adenocarcinoma to the mandible is presented. The patient had undergone a gastrectomy 3 years ago.

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