• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.4
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• pp.464-469
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• 2007

This research was worked out to investigate fermentation and functional properties of Hahyangju. Hahyangju was brewed by traditional method and the changes in chemical component and microorganisms in wine mash were evaluated during brewing. In the course of the first mash brewing, the yeast cell number was the highest after 6 days fermentation, and contained 11% alcohol, 0.82% total acidity and 0.53% amino acidity The final product of Hahyangju contained 19.2% alcohol, 0.32% reducing sugar, 0.46% total acidity and 0.24% amino acidity. The major organic acid was lactic acid containing 680.04mg/100mL. The total phenolic compound contents and electron donating ability of Hahyangju were 263.16 ppm and 93.08%, respectively. Nitrate scavenging effect was measured at various PH (1.2, 3.0, 4.2, 6.0); the highest effect was at pH 1.2 as 90.26%. Angiotensin converting enzyme (ACE) inhibition activity and fibrinolytic activity of Hahyangju ware 87.5% and 19.1 unit, respectively.

• Food Science and Preservation
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• v.14 no.4
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• pp.425-430
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• 2007

To investigate the potential therapeutic value of a plant extract against amyloid ${\beta}-peptide-induced$ cell damage, we first screened extracts of 250 herbs, and finally selected a water extract of Spinacia oleracea for further study. This extractshowed the potential to inhibit the reactions of oxidants. We measured the angiotensin-converting-enzyme (ACE) inhibitory activity of the extract, and assessed the ability of the extract to protect neuronal cells from chemical-induced cell death. SH-SY5Y neuroblastoma cells were used in this assay. The extract exerted protective effects on $H_2O_2-induced$ cell death, when $H_2O_2$ was used at 100 M, 200 M, and 500 M (protection of 87%, 73%, and 58%, respectively). When 50 M of amyloid ${\beta}-peptide$ was added to the test cells, however, the extract had no protective effect on cell death. The extract inhibited ACE activity in a dose-dependent manner, and exhibited potent protection against the deleterious effects of $H_2O_2$. In sum, these results suggest that a water extract of Spinacia oleracea has the potential to afford protection against chemical-induced neuronal cell death, and the extract may be useful in the treatment of neurodegenerative diseases. The precise molecular mechanism of neuroprotection is under investigation.

• Food Science and Preservation
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• v.30 no.2
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• pp.179-189
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• 2023

Consumers and industry experts frequently have negative perceptions of most chemical preservatives. Although most people concede that they cannot resolve global food waste issues without preservatives, they prefer products without chemical preservatives. Numerous emerging technologies is now surpassing conventional methods for mitigating microbial food deterioration in response to consumer demand and fundamental health and safety considerations, including biological antimicrobial systems such as using food-grade microorganisms and their metabolites primarily originating from microorganisms, plants, and animals. Microbial compounds, including bacteriocins, bacteriophages, and anti-fungal agents, plant extracts such as flavonoids and essential oils; and animal-originated compounds, such as lysozyme, chitosan, and lactoferrin, are considered some of the major bio-preservatives. These natural compounds can be used alone or with other preservatives to improve food safety. Hence, the use of microbes or their metabolic byproducts to extend the shelf life of foods while maintaining safety standards is known as bio-preservation. To manufacture and consume foods in a safe condition, this review primarily aims to broaden knowledge amongst industry professionals and consumers regarding bio-preservation techniques, bio-preservatives, their classifications, and distinctive mechanisms to enhance food safety.

• Journal of Korea Technology Innovation Society
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• v.8 no.2
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• pp.860-885
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• 2005

This study relates to develop a quantitative method through which promising technology-based business items can be discovered and selected. For this study, we utilized patent trend analysis, technology-industry concordance analysis, and keyword co-occurrence analysis of US patents. By analyzing patent trends and technology-industry concordance, we were able to find out the emerging industry trends : prevalence of bio industry, service industry, and B2C business. From the direct and co-occurrence analysis of newly discovered patent keywords in the year, 2000, 28 promising business item candidates were extracted. Finally, the promising item candidates were prioritized using 4 business attractiveness determinants; market size, product life cycle, degree of the technological innovation, and coincidence with the industry trends. This result implicates that reliable discovery and selection of promising technology-based business items can be performed by a quantitative, objective and low- cost process using knowledge discovery method from patent database instead of peer review.

• Food Science and Industry
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• v.40 no.4
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• pp.31-39
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• 2007

• Journal of Pharmaceutical Investigation
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• v.34 no.1
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• pp.73-79
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• 2004

The union of information-technology and biology presents great possibilities to both applications of bio-information and development of science and technology. Also, meaningful analysis of bio-information brings about a new innovation in the field of bio-market with the advent and growth of bioinformatics. Hence, bioinformatics is the most import aspect for establishing a science-technology-oriented society in the $21^{st}$ century. This article provides trends in current state of bioinformatics. Technological development of bioinformatics for the rapid growth of bio-industry means that using bioinformatics, a biologist can process and store enormous amount of data such as current Human Genome Project and future data in the field of biology. We have manly looked at the tends of bio-information, databases and mining tools that are generally used, and strategies and directions for the future.

• Food Science and Industry
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• v.43 no.2
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• pp.83-89
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• 2010

• Korean Journal of Fisheries and Aquatic Sciences
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• v.46 no.2
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• pp.111-118
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• 2013

The Norwegian coastal area is the most efficient region for fishery production in the world's oceans, the Norway is the world's top 10 fisheries countries through efficient fishing and fishing aquaculture technology and its scientific management of fisheries bio-resources, with Norwegian salmon having attained the world's highest level. In the late 1980s, fisheries resources were depleted due to overfishing and fish diseases, resulting in a crisis in the fishing industry that lasted until the early 1990s. Since the national fishery emergency, people involved in the fishing industry, including fishermen, research scientists, and government officers, have tried to overcome the challenges facing the industry and identify an appropriate management model for fisheries bio-resources in the Norwegian coastal area. First, research vessels were used to monitor water and sediment conditions and fishery species, with the long-term aim of predicting fishery resources in real time and collecting information on species diversity, abundance, and distribution. Second, a "Healthy Fish Project" was promoted to counter natural disasters and fish disease problems with the development of vaccines against viruses and bacteria, eventually allowing for a decrease in the use of antibiotics and the production of notably healthier fish in the 2000s. Third, a systematic management model was developed to help with preparations for decreases in the total number of fishermen and increases in the proportion of elderly fishermen in the fishery industry using the development of automatic fishing aquaculture systems and short-chain systems. We could learn from the Norwegian model of fisheries bio-resources, management and could adopt it for the preparation of fishery bio-resources management policy for South Korean coastal areas in the near future.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.54 no.1
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• pp.81-88
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• 2018

A study for species composition and abundance of the fish assemblages in the eastern Jinhae Bay, Korea was conducted using monthly larval collection by a RN80 net from October, 2010 to September, 2011. Of all the 45 species collected, the dominant species were Clupea pallasii, Hexagrammos otakii, Pholis fangi and Engraulis japonicus. Clupea pallasii, Hexagrammos otakii, Pholis fangi in winter and examined Engraulis japonicus, Acanthogobius sp., Parablennius yatabei, and Tridentiger trigonocephalus in summer appeared seasonally. Popoulation characteristic by stations was not clear seasonally and spatially, and appearance aspects of dominant species were similar by stations. Compared our results with other studies in the South Sea, dominant species and their appearance period were similar to their spawning period. Finally, the appearance period of the larvae in the South Sea was closely resulted to spawning period rather than the regional characteristic.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.1
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• pp.107-113
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• 2017

The feeding habits of larval (5.0~27.0 mm SL) Clupea pallasii were examined and 1,523 individuals were collected from November 2010 to March 2011 in the coastal water of Eastern Jinhae Bay, Korea. Larval C. pallasii were fed mainly on copepods that constituted 55.2% in IRI. Monogeneans were the second largest prey component, another prey items tintinnids, cladocerans and ostracoda. The results of analysis in ontogenetic changes exhibit high during the daytime, two small size classes (${\leq}10mm$, 10~15 mm) mainly fed copepods. while the percentage of coperpods decreased, monogeneans ratio increased in 15~20 mm size class. Feeding rate in diel difference of larval C. pallasii were high during the daytime.