• Title/Summary/Keyword: Bio data

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A Study on an Estimated Location of Seongjae Ryu, Junggyo's Okgye Gugok in GaPyeong-Gun (성재 유중교의 가평 옥계구곡 위치추정 연구)

  • Kang, Kee-Rae;Lee, Hae-Ju;Lee, Hyun-Chae;Kim, Hee-Chae;Kim, Dong-Phil;Ha, Seung Kun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.35 no.3
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    • pp.32-40
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    • 2017
  • The introduction of neo-Confucianism as the ideological foundation of Joseon, and its root Confucianism have become the origin of the life, scholarship and ideology of the Korean people. Additionally, it was considered the best to follow the teachings of the discipline's advocates including Confucius (孔子), Mencius (孟子), Zisi (子思), ZhuXi (朱子). Among these teachers, ZhuXi was the one who overtly presented the way of self-discipline, of which goal lies in attaining the character by the manifestation of vitality (氣 ki) and rationality (理 i) and contemplating on them. As he regarded natural places with mountains and waters as stages and tools for practicing toward the enlightenment, Confucian scholars in Joseon also followed his example in the spirit of honoring and studying ZhuXi (尊朱子, 學朱子), which became the basic thoughts and practical philosophy among them. Ryu, Junggyo, the neo-Confucian dogmatist, was no exception to applaud the nature, as he designated and ruled Okgye Gugok. On the basis of these backgrounds, this study aims to estimate the geographic places of Okgye Gugok, which was set by Ryu, Junggyo, a Confucian scholar in late-Joseon period, by collecting and analyzing the basic data, starting from Gareung-gun Okgye Sansugi(嘉陵郡玉溪山水記) which is the primary text authored by Seongjae Ryu, Junggyo. The literature study is followed by ten field trips to the estimated locations of Okgye Gugok, and verification of the estimations by three locals who were born and raised in Okgye Gugok. Coordinates and photographs were obtained as spatial data for each location of nine Gok(曲) estimated through this study. They will serve as a primary and critical data for story-telling and tourism resource in Okgye Gugok. The significance of this study is that it provides the primary data for designating the locations of Gok(曲) in Okgyeo Gugok.

Radiotherapy Incidents Analysis Based on ROSIS: Tendency and Frequency (ROSIS 자료 기반 방사선 사고 사례 분석 : 경향과 빈도)

  • Koo, Jihye;Yoon, MyongGeun;Chung, Won Kuu;Kim, Dong Wook
    • Progress in Medical Physics
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    • v.25 no.4
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    • pp.298-303
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    • 2014
  • In this study, we examine the trends and types of incidents frequently occur during radiation therapy by using the data from the radiation oncology safety information system (ROSIS), according to discovery method explores the development direction of future research accident cause factor control method. This study was carried out analysis of incident data in ROSIS nearly 1163 cases in last 11 years from 2003 to 2013. We categorized into treatment methods, found the time, discoverer of occupations and finding ways to analyze the data. Then, we calculate the percentage and the classification for each item. About 1163 cases of incident cases including the near miss cases, external radiation therapy, brachytherapy and other were 97%, 2% and 1%. In the case was improperly planned dose delivery was 44% (497 cases) which 429 cases (86%) was found before 3 fractions and 13 cases were found after 11 fractions. The investigation was found to be distributed in various a found times. Approximately 42% of found time was during treatment and 29% of patients were found the problem during inspection chart. Occupation to discover the most radiation accidents was the radiation therapist (53%) who works in treatment room. Among 1163 incidence cases, 24% cases were found the accident before the treatment, therefore most of accident were found after of during the treatment (70%, 813 cases). This trend is acquired through ROSIS analysis, is expected to be not significantly different in the case of Korea, so it is necessary more diverse and systematic research for the prevention and early detection by using the ROSIS data.

Analysis of Trans-splicing Transcripts in Embryonic Stem Cell (배아줄기세포에서 트랜스 스플라이싱 전사체의 분석)

  • Ha, Hong-Seok;Huh, Jae-Won;Kim, Dae-Soo;Park, Sang-Je;Bae, Jin-Han;Ahn, Kung;Yun, Se-Eun;Kim, Heui-Soo
    • Journal of Life Science
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    • v.19 no.4
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    • pp.549-552
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    • 2009
  • Genetic mutations by gene fusion result from chromosomal rearrangement, trans-splicing, and intergenic splicing. Trans-splicing is a phenomenon in which two pre-mRNAs grow together into one. We analyzed the trans-splicing products in embryonic stem cells. By using bioinformatic tools, 70 trans-splicing transcripts were identified. They are classified into 6 types according to fusion pattern: 5'UTR-5'UTR, 5'UTR-3'UTR, 3'UTR-3'UTR, 5'UTR-CDS, 3'UTR-CDS, CDS-CDS. The fusion products are more abundant in CDS regions than in UTR regions, which contain multiple intron numbers. Chromosome analysis showing gene fusion via trans-splicing indicated that chromosomes 17 and 19 were activated. These data are of great use for further studies in relation to fusion genes and human diseases.

Factors Influencing Frequency of Abnormal Peak in the Measurement of HbA1c by HPLC (HPLC법을 이용한 HbA1c 측정시 Abnormal Peak의 빈도와 원인)

  • Kim, Sun-Kyung;Bae, Ae-Young;Choi, Dae-Yong;Kim, Myung-Soo;Yoo, Kwang-Hyun;Ki, Chang-Seok
    • Korean Journal of Clinical Laboratory Science
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    • v.37 no.2
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    • pp.71-77
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    • 2005
  • We experienced the specimen that contains a hemoglobin variant known as interference from HbAS in October 2003. It was the first case of Hb variants since Samsung Medical Center began conducting glycohemoglobin College of American Pathologists surveys in 1997. The purpose of this study is to share our experience with the specimen and promote the understanding of Hb variants & derivatives. We've performed cross checks to examine HbA1c by using two pieces of equipment; the TOSHOH G7 and BIO-RAD VARIANT-T(turbo), and Automatic High Performance Liquid Chromatography(HPLC) as an analytic measurement method. HPLC provides different fractional information of hemoglobin with a two-dimensional graph as well as numeric results. We have been performing a "Systematic Checking Process". Three specimen suspicious of Hb variants & derivatives were found through this process. College of American Pathologists notified that it is important for users to be aware of the limitation of their glycohemoglobin method to avoid reporting incorrect results due to interference from hemoglobin variants or hemoglobin adducts. Therefore, laboratory findings of Hb variants & derivatives are very important. The experience of qualified technicians with professional knowledge in Hb variants is the most important aspect in finding Hb variants. Korea is homogeneous in race and is not in an area with a higher finding rate of Hb variants. While 1,024 cases of Hb variants have been found in Japan, we do not have specific data on how many cases of Hb variants have been found in Korea. Considering Hb variant cases in Japan, which is geographically close to us, it is presumed that there must be various Hb variant cases in Korea. If domestic laboratories set a systemic protocol and build a network to share our experience in Hb variants, I expect the Korean Hb variants could also be listed on the world's Hb variant list.

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Research on the modified algorithm for improving accuracy of Random Forest classifier which identifies automatically arrhythmia (부정맥 증상을 자동으로 판별하는 Random Forest 분류기의 정확도 향상을 위한 수정 알고리즘에 대한 연구)

  • Lee, Hyun-Ju;Shin, Dong-Kyoo;Park, Hee-Won;Kim, Soo-Han;Shin, Dong-Il
    • The KIPS Transactions:PartB
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    • v.18B no.6
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    • pp.341-348
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    • 2011
  • ECG(Electrocardiogram), a field of Bio-signal, is generally experimented with classification algorithms most of which are SVM(Support Vector Machine), MLP(Multilayer Perceptron). But this study modified the Random Forest Algorithm along the basis of signal characteristics and comparatively analyzed the accuracies of modified algorithm with those of SVM and MLP to prove the ability of modified algorithm. The R-R interval extracted from ECG is used in this study and the results of established researches which experimented co-equal data are also comparatively analyzed. As a result, modified RF Classifier showed better consequences than SVM classifier, MLP classifier and other researches' results in accuracy category. The Band-pass filter is used to extract R-R interval in pre-processing stage. However, the Wavelet transform, median filter, and finite impulse response filter in addition to Band-pass filter are often used in experiment of ECG. After this study, selection of the filters efficiently deleting the baseline wandering in pre-processing stage and study of the methods correctly extracting the R-R interval are needed.

Human Exposure Assessment of Pesticide Residues in Cattle by-product Fed the Rice Straw (농약이 잔류된 볏짚조사료을 급여한 소의 부산물 섭취에 따른 인체노출평가)

  • Gil, Geun-Hwan;Paik, Min-Kyoung;Kim, Jin-Bae;Kim, Chan-Sub;Son, Kyung-Ae;Im, Geon-Jae;Ihm, Yang-Bin;Lee, Kyu-Seung
    • The Korean Journal of Pesticide Science
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    • v.17 no.4
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    • pp.249-255
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    • 2013
  • The objective of this study was to investigate the exposure assessment of Korean consumers to edifenphos and tricyclazole in cattle product fed the rice straw, using a probabilistic approach. We used tricyclazole and edifenphos residue data in rice straw reported by National Academy of Agricultural Science (NAAS) for the 1998, 1999, 2001 and 2010 monitoring study and National Agricultural Products Quality Management Service (NAQS) for 2009 monitoring study. The mean exposures of edifenphos and tricyclazole for all of Korean consumers were 0.027% and 0.0006% of ADI and $99%^{th}$ percentile exposures were 0.034% and 0.0007% of ADI respectively. The group of 1~6 years old consumers has the lowest exposure of edifenphos and tricyclazole. The group of 19~29 years old consumers has the highest exposure of edifenphos and tricyclazole.

BIO-PSYCHOSOCIAL STUDY OF EMOTIONAL BEHAVIORAL PROBLEMS IN KOREAN ELEMENTARY SCHOOL CHILDREN (I) - An Epidemiological Study of Emotional Behavioral Problems in Korean Elementary School Children by Rutter's Questionnaire - (국민학교아동의 정서행동문제에 대한 생물${\cdot}$정신사회학적 연구 (I) - Rutter의 아동행동평가표에 의한 국민학교아동의 정서행동문제조사 -)

  • Jang, Kyung-June;Lee, Chung-Kyoon;Hong, Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.1 no.1
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    • pp.94-107
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    • 1990
  • The survey of emotional behavioral problems in elementary school children provide baseline data for understanding, treating and preventing emotional behavioral problems in children. Since children can show different behaviors at home and at school, parents' information alone can lead to underestimate severity and prevalence rate of emotional behavioral problems in children. Thus, the author investigated the different the pattern of emotional behavioral problems in elementary school children by various socio-enviornmental factors in urban(Seoul) and rural area, by employing both parents' and teachers' questionnaire. The results were as follows ; Analysis of Rotter's questionnaire, in which high scores mean more serious emotional behavioral problems than low scores. The mean total problems scores for rural elementary school children were higher than those of Seoul elementary school children, and boys showed higher scores than girls. In relation to grade, mena total problems scores diminished as grade increased up to 4th or 5th, and then relatively high score for the 6th grade. Parent's education had significant effect on the total problem scores, that children of less educated parents showed higher score than children of more educated parents. Likewise the highest score was observed in children of unemployed parents. These results demonstrated that emotional behavioral children are related to various socio-environment factors.

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Effect of nanosilica and TEOS in hydrophilic coating solution on the surface characteristics of solar cell glass panel (나노실리카와 TEOS가 함유된 친수성 코팅액의 태양광 유리팬널에 미치는 표면 특성 연구)

  • Lee, Soo;Kim, Seung Hye;Hwang, Heon
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.1
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    • pp.152-162
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    • 2017
  • A hydrophilic coating solution was prepared by adding a silane coupling agent and a nano-inorganic oxide in aqueous surfactant solution to increase the efficiency of photovoltaic power generation due to the introduction of antifogging and antifouling properties on the glass surface of the solar cell module. Addition of $Ludox^{(R)}$, a nano-inorganic oxide, to 1% hydrophilic coating solution showed improved hydrophilicity and excellent antifogging effect regardless of $Ludox^{(R)}$ concentration. However, the antifouling effect on the glass surface was showed only when Ludox was added more than 10%. In the case of addition of 0.7% of hydrolyzed TEOS at pH 4, the antifogging effect was maintained as a result of the steam test as well as the antifouling effect even after the coated glass surface was rubbed 100 times with a wet Kimwipe. In addition, from the surface roughness ($R_q$) calculated using AFM data, the higher surface roughness with irregular surface shape was obtained with the higher concentration of TEOS. The addition of 0.7% of TEOS showed relatively high surface roughness and well organized surface condition which can help to improve transmittance of light. In conclusion, $Ludox^{(R)}$ is not required only for the antifogging property. However, at least 10% of Ludox should be added to show antifouling effect and 0.7% of TEOS should be added for good durability.

A Study on the Improvement Scheme of University's Software Education

  • Lee, Won Joo
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.3
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    • pp.243-250
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    • 2020
  • In this paper, we propose an effective software education scheme for universities. The key idea of this software education scheme is to analyze software curriculum of QS world university rankings Top 10, SW-oriented university, and regional main national university. And based on the results, we propose five improvements for the effective SW education method of universities. The first is to enhance the adaptability of the industry by developing courses based on the SW developer's job analysis in the curriculum development process. Second, it is necessary to strengthen the curriculum of the 4th industrial revolution core technologies(cloud computing, big data, virtual/augmented reality, Internet of things, etc.) and integrate them with various fields such as medical, bio, sensor, human, and cognitive science. Third, programming language education should be included in software convergence course after basic syntax education to implement projects in various fields. In addition, the curriculum for developing system programming developers and back-end developers should be strengthened rather than application program developers. Fourth, it offers opportunities to participate in industrial projects by reinforcing courses such as capstone design and comprehensive design, which enables product-based self-directed learning. Fifth, it is necessary to develop university-specific curriculum based on local industry by reinforcing internship or industry-academic program that can acquire skills in local industry field.

Analysis for Concentration Range of Fluorescein Sodium (플루오레신나트륨의 농도 범위 분석)

  • Lee, Da-Ae;Kim, Yong-Jae;Yoon, Ki-Cheol;Kim, Kwang-Gi
    • Journal of Biomedical Engineering Research
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    • v.41 no.2
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    • pp.67-74
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    • 2020
  • Brain tumors or gliomas are fatal cancer species with high recurrence rates due to their strong invasiveness. Therefore, the goal of surgery is complete tumor resection. However, the surgery is difficult to distinguish the border because tumors and blood vessels have the same color tone and shape. The fluorescein sodium is used as a fluorescence contrast agent for boundary separation. When the external light source is irradiated, yellow fluorescence is expressed in the tumor, which helps distinguish between blood vessels and tumor boundaries. But, the fluorescence expression of fluorescence sodium depends on the concentration of fluorescein sodium and such analytical data is insufficient. The unclear fluorescence can obscure the boundaries between blood vessels and tumors. In addition, reduce the efficiency of fluorescence sodium use. This paper proposes a protocol of concentration range for fluorescence expression conditions. Fluorescent expression was observed using a near-infrared (NIR) color camera with corresponding dilution using normal saline in 1 ml microtube. The flunoresence emission density range is 1.00 mM to 0.15 mM. The fluorescence emission begin to 1.00 mM and the 0.15 mM discolor. The discolor is difficult to fluorescence emission condition obserbation. Thus, the maximum density range of the bright fluoresecein is 0.15 mM to 0.30 mM. When the concentration range of fluorescein sodium is analyzed based on the gradient of fluorescence expression and the power measurement, the brightest fluorescence is expected to facilitate the complete resection of the tumor. For the concentration range protocol, setting concentration ranges and analyzing fluorescence expression image according to saturation and brightness to find optimal fluorescence concentration are important. Concentration range protocols for fluorescence expression conditions can be used to find optimal concentrations of substances whose expression pattern varies with concentration ranges. This study is expected to be helpful in the boundary classification and resection of brain tumors and glioma.