• Title/Summary/Keyword: Bio Venture

Search Result 162, Processing Time 0.019 seconds

Molecular Recognition of Neutral Substrates by New Tetraaminocalix[4]arene Derivative

  • Nimse, Satish Balasaheb;Song, Keum-Soo;Jung, Chan-Yong;Eoum, Woon-Yong;Kim, Tai-Sun
    • Bulletin of the Korean Chemical Society
    • /
    • v.30 no.6
    • /
    • pp.1247-1251
    • /
    • 2009
  • The recognition of neutral aromatic substrates by different neutral calix[4]arene receptors 1, 2, and 3 was studied by NMR spectroscopy. The stoichiometry is 1:1 in all cases as was confirmed by jobs plot. Owing to the deep cavity, 1 affords stronger binding abilities for substrate 4 and 5, while all receptors remained inert for substrates 6 and 7. The binding constants determined by $^1H$ NMR titration show that the recognition of substrate 4 by 1 gives strongest complexation ($K_a\;of\;9.8\;{\times}\;102\;M^{-1}$).