• Title/Summary/Keyword: Bio Chip

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A bio-sensor SoC Platform Using Carbon Nanotube Sensor Arrays (CNT 배열을 이용한 bio-sensor SoC 설계)

  • Chung, In-Young
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.12
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    • pp.8-14
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    • 2008
  • A fully CMOS-integrated carbon nanotube (CNT) sensor array is proposed. After the sensor chip is fabricated in commercial CMOS process, the CNTs network is formed on the top of the fabricated sensor chip through the room-temperature post-CMOS processes. When the resistance of the CNT is changed by the chemical reaction, the read-out circuit in the chip measures the charging time of the $R_{CNT}$-Capacitor. finally the information of measured frequency is converted to a digital code. The CMOS sensor chip was fabricated by standard 0.18um technology and the size of the $8{\times}8$ sensor array is $2mm{\times}2mn$. We have carried out an experiment detecting the biochemical material, glutamate, using this sensor chip. From the experiment the CMOS sensor chip shows the feasibility of sensor for the simultaneous detection of the various target materials.

Development of Agricultural Production Environmental Controller (농업생산 시설의 무인 관리용 제어시스템의 개발)

  • 전재근;전정렬
    • Proceedings of the Korean Society for Bio-Environment Control Conference
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    • 1993.05a
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    • pp.11-11
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    • 1993
  • 농업 생산시설의 환경제어장치를 one chip microcomputer를 사용하여 설계, 제작하였으며 실시간 복합 제어 기능을 수행할 수 있는 운영 프로그램을 개발하였다. 제어 장치의 microcomputer 는 6 개의 analog input 선을 포함하여 45 개의 입.출력선을 가진 8 bit microcomputer chip을 사용하였다. 농업환경인 온도, 습도, 조도는 센서를 직접 접속하여 계측 할 수 있도록 계측 module을 포함시켰다. (중략)

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Variation of Adenosine tri-Phosphate(ATP) in Fermentation-Extinction of Food Wastes with Wood Bio-Chip (목질바이오칩에 의한 음식물쓰레기 발효-소멸반응에서의 아데노신3인산의 변화)

  • Oh, Jeong-Ik
    • Journal of Korean Society of Environmental Engineers
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    • v.32 no.4
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    • pp.363-368
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    • 2010
  • The overall indicator of microbial activity in the fermentation-extinction reaction of food waste by using bio wood-chips were investigated by considering adenosine tri-phosphate(ATP). Degradation rate of organic compounds, which was represented by chemical oxygen demand(COD) and total nitrogen(TN), was increased with the concentration of adenosine tri-phosphate during fermentation-extinction reaction of food waste by using bio-wood chips. With this view, the ATP would be one of the overall evaluation indicator of organic degradation in the species of bio-wood chip for the fermentation-extinction of food waste.

Studies on the Selection of Microorganism for Food Wastes and Optimization of Fermentation Process (음식물찌꺼기 소멸효율 재고를 위한 발효균 및 발효 공정 최적화 연구)

  • Kim, Young-Kwon;Hong, Myung-Pyo;Kim, Myung-Jin;Hong, Suk-Il;Park, Myung-Suk;Kim, Jong-Suk;Chang, Ho-Geun
    • Journal of the Korea Organic Resources Recycling Association
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    • v.6 no.2
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    • pp.95-112
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    • 1998
  • For the effective disposal of organic food wastes, we seleted 4 strains of microorganism from 186 microbial candidate via enzyme activity test, salt tolerance, food decomposition rate, stability and safety of strains. The identity of these 4 strains are as follows : Fungi is Rhizopus sp., yeasts are Galactomyces sp., Pichia sp. and Hyphopichia sp., In the 50L fermenter scale, we tested various fermenting factor for the optimization of conditions of food waste decomposition using 4 selected strains. The optimum fomenting conditions were as follows : BIO-CHIP Volume 25-30 L, BIO CHIP size 2.0-6.0mm, air flow 200-280L/min, mixing intensity 2-4rpm, temperature $30-45^{\circ}C$. In these fermenting conditions, the efficiency of decomposition(rate of weight loss of food wastes) were 93%. Also the quality of fermenting output were assayed at the basis of fertilizer, and the results were as good as general compost.

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On-chip Magnetic Sensor with Embedded High Inductance Coil for Bio-magnetic Signal Measurement (생체자기 신호측정을 위한 고인덕턴스 코일 내장형 온칩 자기센서)

  • Lyu, HyunJune;Choi, Jun Rim
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.6
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    • pp.91-98
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    • 2013
  • Magnetic sensor chip for measuring bio-magnetism is implemented in $0.18{\mu}m$ CMOS technology. The magnetic sensor chip consists of a small-sized high inductance coil sensor and an instrumentation amplifier (IA). High inductance coil sensor with suitable sensitivity and bandwidth for measurement of bio-magnetic signal is designed using electromagnetic field simulation. Low gm operational transconductance amplifier (OTA) using transconductance reduction techniques is designed for on-chip solution. Output signal sensitivity of magnetic sensor chip is $3.25fT/{\mu}V$ and reference noise of 21.1fT/${\surd}$Hz. Proposed IA is designed along with band pass filters(BPF) to reduce magnetic signal noise by using current feedback techniques. Proposed IA achieves a common mode rejection ratio of 117.5dB while the input noise referred is kept below $0.87{\mu}V$.

Nano SPR Biosensor for Detecting Lung Cancer-Specific Biomarker (폐암 바이오마커 검출용 나노SPR 바이오센서)

  • Jang, Eun-Yoon;Yeom, Se-Hyuk;Eum, Nyeon-Sik;Han, Jung-Hyun;Kim, Hyung-Kyung;Shin, Yong-Beom;Kang, Shin-Won
    • Journal of Sensor Science and Technology
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    • v.22 no.2
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    • pp.144-149
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    • 2013
  • In this research, we developed a biosensor to detect lung cancer-specific biomarker using Anodic Aluminum Oxide (AAO) chip based on interference and nano surface plasmon resonance (nanoSPR). The nano-porous AAO chip was fabricated $2{\mu}m$ of pore-depth by two-step anodizing method for surface uniformity. NanoSPR has sensitivity to the refractive index (RI) of the surrounding medium and also provides simple and label-free detection when specific antibodies are immobilized to the Au-deposited surface of nano-porous AAO chip. To detect the lung cancer-specific biomarker, antibodies were immobilized on the surface of the chip by Self Assembled Monolayer (SAM) method. Since then lung cancer-specific biomarker was applied atop the antibodies immobilized layer. The specific reaction of the antigen-antibody contributed to the change in the refractive index that cause shift of resonance spectrum in the interference pattern. The Limit of Detection (LOD) was 1 fg/ml by using our nano-porous AAO biosensor chip.