• 공연문화연구
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• 제19호
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• pp.35-60
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• 2009

이 글은 현재 연행되고 있는 자인단오제의 큰굿의 구조에 문제가 있음을 지적하면서 구조를 새롭게 정립해야 함을 주장한 글이다. 현재 자인단오제에는 큰굿이 연행되고 있으나, 굿거리와 공연물이 복합적으로 얽혀 있어 굿거리의 성격이 모호하다. 그러다보니 한국 무속의 구조에 맞지 않은 이상한 굿거리들이 연행되고 있는데, 패왕별희, 어우동 거리 등이 그 예이다. 세부적인 절차도 어색하여 지역의 특색을 드러내기보다는 우리나라 각 지역의 무속 양상이 혼합되어 있다. 바라를 팔다가 고를 푸는 칠성거리가 그 예이다. 또한 개별 굿거리에 다수의 무당이 등장하여 춤을 추면서 굿을 연행하고 있어 굿이라기 보다는 무용극 내지는 춤공연으로 보이는 것도 문제이다. 이러한 문제점이 극복되어야 큰굿은 우리의 소중한 문화 자산이 될 수 있다. 따라서 한국굿의 구조를 고려할 때 초반부, 중반부, 종반부의 구성을 지키면서 굿거리의 층위를 신령의 체계와 맞출 필요가 있다. 굿거리가 아닌 것들은 과감하게 빼버려서 굿거리 중심의 연행물이 되어야 한다. 개별 굿거리를 담당하는 주무를 설정하고 주무 중심으로 굿을 진행해야 한다. 현재 담당하고 있는 이들이 문제가 있다면 경상도 내륙의 무속 사정을 잘 아는 새로운 연행담당층을 모색하는 것도 한 방법이 된다. 자인단오제 큰굿은 이제 무형문화재의 일부이다. 과거처럼 사람들의 흥미에 부응하고 호기심의 대상이 되는 공연물이 아닌 우리의 전통 문화를 대표하는 전승물이 되어야 한다. 지금까지 연행된 굿거리를 재검토하여 획기적으로 다시 재편해야 할 시점에 와있다.

• Annals of Coloproctology
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• 제34권6호
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• pp.280-285
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• 2018

For many years, developmental and physiological differences have been known to exist between anatomic segments of the colorectum. Because of different outcomes, prognoses, and clinical responses to chemotherapy, the distinction between right colon cancer (RCC) and left colon cancer (LCC) has gained attention. Furthermore, variations in the molecular features and gut microbiota between right and LCCs have recently been a hot research topic. CpG island methylator phenotype-high, microsatellite instability-high colorectal cancers are more likely to occur on the right side whereas tumors with chromosomal instability have been detected in approximately 75% of LCC patients and 30% of RCC patients. The mutation rates of oncogenes and tumor suppressor genes also differ between RCC and LCC patients. Biofilm is more abundant in RCC patients than LLC patients, as are Prevotella, Selenomonas, and Peptostreptococcus. Conversely, Fusobacterium, Escherichia/Shigella, and Leptotrichia are more abundant in LCC patients compared to RCC patients. Distinctive characteristics are apparent in terms of molecular features and gut microbiota between right and LCC. However, how or to what extent these differences influence diverging oncologic outcomes remains unclear. Further clinical and translational studies are needed to elucidate the causative relationship between primary tumor location and prognosis.

• 한국의류산업학회지
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• 제17권3호
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• pp.364-371
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• 2015

This study investigated and analyzed Sadanggut for General Namyi, Agisee Gutdang in Haengdang-dong, Dodanggut in Bonghwa Mountainto examine the type and characteristics of official hats for shaman's costumes based on Seoul village gutas a spiritualistic shaman revealing the divinity of music for gutthrough singing, dancing, divine material and official hats. Commonly worn official hats were Goggal(conical hats), Jeonlip(soldier's felt hats), and Heuklip(black hats) for Seoul village gut as the object of thisstudy. Each official hat had a close relationship with subjects for divinity and musical meaning for gut. Julip(Red hats), Jokduri(bride's headpiece), helmets, Iksubgwan(King's official hat), and Daesu(Queen's a big wig with various hairpins) were also worn. Official hats worn for Seoul village gutwere understood to symbolize divinity and raise authority and dignity to the public through aggressive appearance, exaggeration and splendor. Concretely, official hats at Seoul village gut first had roles to materialize the divinity of each music of gut. Second, recognized as a part of performance or traditional culture in present day, aggressive official hats were favored to supply splendid attraction and maximize scenes of divined heroic epic poem in gut. Third, for Seoul village gut, colors and silhouettes of modern traditional costumes were reflected pursuing partial change and focused on exaggeration and splendor to express the mirth and festival of gutwhile maintaining traditional costumes.

• Journal of Ginseng Research
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• 제45권2호
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• pp.334-343
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• 2021

Background: Gut microbiota mainly function in the biotransformation of primary ginsenosides into bioactive metabolites. Herein, we investigated the effects of three prebiotic fibers by targeting gut microbiota on the metabolism of ginsenoside Rb1 in vivo. Methods: Sprague Dawley rats were administered with ginsenoside Rb1 after a two-week prebiotic intervention of fructooligosaccharide, galactooligosaccharide, and fibersol-2, respectively. Pharmacokinetic analysis of ginsenoside Rb1 and its metabolites was performed, whilst the microbial composition and metabolic function of gut microbiota were examined by 16S rRNA gene amplicon and metagenomic shotgun sequencing. Results: The results showed that peak plasma concentration and area under concentration time curve of ginsenoside Rb1 and its intermediate metabolites, ginsenoside Rd, F2, and compound K (CK), in the prebiotic intervention groups were increased at various degrees compared with those in the control group. Gut microbiota dramatically responded to the prebiotic treatment at both taxonomical and functional levels. The abundance of Prevotella, which possesses potential function to hydrolyze ginsenoside Rb1 into CK, was significantly elevated in the three prebiotic groups (P < 0.05). The gut metagenomic analysis also revealed the functional gene enrichment for terpenoid/polyketide metabolism, glycolysis, gluconeogenesis, propanoate metabolism, etc. Conclusion: These findings imply that prebiotics may selectively promote the proliferation of certain bacterial stains with glycoside hydrolysis capacity, thereby, subsequently improving the biotransformation and bioavailability of primary ginsenosides in vivo.

• 미생물학회지
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• 제55권3호
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• pp.268-273
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• 2019

장 내에 존재하는 microbiome은 생활환경, 나이와 섭취하는 음식물에 따라 변하게 된다. 본논문에서는 모유를 섭취한 영아와 분유를 섭취한 영아들에 대한 장내미생물 군집의 변화를 비교하였다. 미생물의 군집변화를 차세대 염기서열 분석기법을 이용하여 분석하였으며 총 80개의 영아 분변을 통해 미생물 군집변화를 확인하였다. 모유그룹(BIG)과 분유그룹(FIG-A, FIG-B, FIG-C)간의 장내세균의 군집을 비교한 결과 BIG에서는 Actinobacteria 문이 전체 군집의 $74.22{\pm}3.48%$로 우점을 차지하였다. 분유그룹의 Actinobacteria 문을 비교하였을 때 FIG-A는 $73.46{\pm}4.12%$였지만 FIG-B와 FIG-C는 $66.52{\pm}5.80%$와 $68.88{\pm}4.33%$로 BIG와 FIG-A에 비해 낮은 비율을 보였다. 속(genus) 수준에서 살펴보면 Bifidobacterium이 전체 미생물군집에서 가장 높은 비율로 분포하고 있었으며 BIG가 $73.09{\pm}2.31%$로 가장 높았고 FIG-A, FIG-B 및 FIG-C는 각각 $72.25{\pm}4.93%$, $63.81{\pm}6.05%$ 및 $67.42{\pm}5.36%$를 차지하였다. Bifidobacterium 종의 경우 모든 그룹에서 Bifidobacterium longum이 우점을 차지하고 있었으며 BIG와 FIG-A가 전체 군집의 $68.77{\pm}6.07%$와 $66.85{\pm}5.80%$를 차지하였다. 이에 반해 FIG-B와 FIG-C는 각각 $58.94{\pm}6.20%$와 $61.86{\pm}5.31%$로 BIG와 FIG-A보다 낮은 비율로 분포하는 것을 분석하였다. FIG-A가 섭취한 분유는 Bifidobacterium의 선택적 증식이 우수하다고 알려진 갈락토올리고당, 갈락토실락토스, 시너지올리고당, 비피도올리고 및 장내균총개선소재를 혼합한 5-Bifidus factor 복합물이 포함되어 있다. 이와 같은 5-Bifidus factor라는 유산균에 대한 증식능이 우수한 프리바이오틱스를 혼합하였기 때문에 모유를 섭취한 영아의 장내에 존재하는 Bifidobacterium 속의 군집과 유사하게 나타난 것으로 판단된다.

• 통합자연과학논문집
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• 제10권4호
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• pp.202-208
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, Hologram based Quantitative Structure Activity Relationship Study was performed on a series of Xanthine Oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best HQSAR model was obtained using Atoms, Bonds, Connection, Hydrogen, Chirality and Donor Acceptor as fragment distinction parameter using hologram length 71 and 4 components with fragment size of minimum 2 and maximum 5. Significant cross-validated correlation coefficient ($q^2$= 0.563) and non cross-validated correlation coefficients ($r^2$= 0.967) were obtained. The model was then used to evaluate the six external test compounds and its $r^2{_{pred}}$ was found to be 0.798. Contribution map show that presence of propyl ring in indole thiazole makes big contributions for improving the biological activities of the compounds. We hope that our HQSAR model and analysis will be helpful for future design of xanthine oxidase antagonists.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2006년도 제47회 학술심포지움 및 추계국제학술대회
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• pp.72.2-72.2
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• 2006

• 한국의류산업학회지
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• 제18권5호
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• pp.588-594
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• 2016

The outer clothing of shaman that are put on while performing current gutgeori is lacking in form and composition, diversified with kinds. Above all, name of shaman clothing is not unified, accordingly, there's a big difference from traditional Gutgeori, which was definitely divided in the role of outer clothing of shaman in respect of function and role of Gutgeori. Here, this research attended a site that performed Gutgeori based on the advanced literature research data research and analyzed the state and name of outer clothing by conducting a survey and interview investigation. Survey was conducted during 2 years from 2014 to 2015 classifying Gutgeori of Seoul, Gyeongsang, Honam, Jeju, Chungcheon. Research results are as follows. First, lots of outer clothes were put on along with shamanism type in Seoul, accordingly, names were diversified. Name of outer clothing was not unified by focusing on level of divinity or behavior of Gutgeori, with no consistency being mixed. Second, name was not consistent even the outer clothing of the same type shaman along with the region, sometimes put on in different meaning, accordingly, called in different name. Combination of such name of shaman is determined to be a big reason of lack of accurate information on shaman clothing and genealogy of name of shaman clothing in shamans, as the initial research on shamanism was conducted by folklorists in advance.

• 한국축산식품학회지
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• 제33권2호
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• pp.229-238
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• 2013

Lactic acid bacteria (LAB) are added to different food products for a long time due to health beneficial effects on human host. LAB is applied in dairy products, such as yoghurt, cheese, and various fermented products, and also in non-dairy products, such as sausages. However, reaching the human gut alive as well as in a sufficient cell amount to exert positive health effects is still a big challenge, due to LAB sensitive character and vulnerability against harsh and detrimental conditions in human digestive system. Keeping physiological activity of sensitive LAB strains alive is for the formulation of novel food products with a probiotic health claim of utmost interest, thus microencapsulation has been applied and investigated as a promising technique for a good and reliable protection. Microencapsulation allows reduced cell injury or cell loss by retaining cells within the encapsulating membrane and can be enforced by spray-drying, emulsion, extrusion, and a range of other technologies in combination with an appropriate coating material, such as alginate, chitosan, and mixture of these two polymers. In this review, established and well-studied microencapsulation techniques with their favored coating materials, as well as the recent applications of microencapsulated LAB into dairy products will be discussed.

• 미생물학회지
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• 제9권2호
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• pp.69-73
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• 1971

On June in 1970 the authors discovered a pathogenecity, cytoplasmic polyhedrosis virus, of the Smithia virus in the larvae of Liparis dispay L. appeared on quercus forest in Chung-Neung district and had carried out a experiment to detect the pathogenecity of Smithia virus through the inoculation of it into the larvase, such as Liparis dispay L. Hyphantrea cunea DRURY, and Dendrolinus spectabilis BUTLER. The results obtained were as follows ; 1) Death rate of L.dispay and D.spectabilis treated by 10$^{6}$ /ml cytoplasmic polyhedrosis virus of Smithis virus were 88.0% and 85.5% respectively, when the larvaes of these insects are big enough. But there were none of pathogenecity in case of Hyphantrea cunea DRURY. 20 Dead larvae caused by the injection of Smithia virus had begum to find out about on 10 days after inoculation. Miximum death rate of L. didpay and D. spectabilis appeared on 20-25days nad on 25-30days, respectively, after the incoulation. 3) In the cytoplasm of Mid-gut cylindrical cells of both of these insects, polyhedrosis, such s hexagonal (0.5-2.0-6.0 micron) were found out and in these insects, polyhedrosis, such as hexaginal (0.5-2.0-6.0 mivton) were found out and in case of D.spectabilis were a few polyhedrosis, such as tetragonal, trianglar polyhedrosis. 4) Diluted concentration of `0$^{6}$ /ml cytoplasmic polyhedrosis virus of Smithia virus were spread out in the field conditions. The corrected mortality was confirmed as about 87.8%.