• The Korean Journal of Pain
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• v.12 no.1
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• pp.8-15
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• 1999

Following peripheral nerve injury, rats will show a tactile allodynia and hyperalgesia. But the mechanism of allodynia is still obscure. The present studies, using rats rendered allodynia by loosely constrictive ligation of the common sciatic nerve (Bennett Model) and tight ligation of L5 & L6 spinal nerve (Chung Model), aimed to investigate the changes of metabotrophic glutamate receptor type 5 on the development of tactile allodynia. Male Sprague-Dawley rats (130~200 g) were anesthetized with halothane, the rats were randomly divided into one of these three groups, Group 1 (Sham operation), Group 2 (Bennett model) and Group 3 (Chung model). Seven days after surgical procedure, the animal was reanesthetized and decapitated. The spinal cord was quickly removed and stored at deep freezer for polymerase chain reaction (RT-PCR). In Group 2&3, rats showed that tactile allodynia checked by up-down method with calibrated 8 von Frey hair. The level of gene expression of mGluR5 mRNA was significantly increased in group 2 and 3. These increases was significantly different from sham operation, group 1. It was also showed that the increasing patterns of group 2 and 3 in the gene expression were similar correlation with the results of the threshold for tactile allodynia on von Frey hair test. Even though there were some differences between Bennett model and Chung model, these results suggested that mGluR5 had partly attributed to making a tactile allodynia from these models.

• (The)Korea Educational Review
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• v.18 no.1
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• pp.283-302
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• 2012

Multicultural families have literally started to settle in Korea since the late 1980s, yet it was not until the middle of 2000 that multicultural education was actually arisen with its full-scale discussions. Domestic studies on multicultural education have now remarkably been conducted in various aspects and points of views, but with no certain level of collective and comprehensive analysis yet. To seek Korean way of finding out appropriate solutions to its multicultural society, a contemporary major trend in the world, it is necessary to keep developing the theory and practice in Korean multicultural education with constructive criticism over the development. In this thesis, the research trends and characteristics of Korea multicultural education are analyzed according to the three categories: the times of the study, the subjects of the study, and the themes of the study. The analysis of the study themes, in particular, is done based on the four core areas presented by Bennett: equity pedagogy, curriculum reform, multicultural competence, and societal equity. Furthermore, the analysis includes the five additional Korean sub-categories, which are also acquired in the process of our analysis of the thesis: multiculturalism, global multicultural education, counselling research, measurement development, and citizenship education, added to Bennett's three sub-ones of each area. Overall, based on the analysis data, this study investigates further improvements and subsequent research themes in the following researches on Korean multicultural education.

• Journal of Korean Biological Nursing Science
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• v.4 no.1
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• pp.101-112
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• 2002

Peripheral nerve injury results in plastic changes in the dorsal ganglia (DRG) and spinal cord, and is often complicated with neuropathic pain. The mechanisms underlying these changes are not known, but these changes seem to be most likely related to the neurotrophic factors. This study investigated the effects of mechanical peripheral nerve injury on expression of brain-derived neurotrophic factor(BDNF) in the DRG and spinal cord in rats. 1) Bennett model and Chung model groups showed significantly increased percentage of small, medium and large BDNF-immunoreactive neurons in the ipsilateral $L_4$ DRG compared with those in the contralateral side at 1 and 2 weeks of the injury. 2) In the ipsilateral $L_5$ DRG of the Chung model, percentage of medium and large BDNF-immunoreactive neurons increased significantly at 1 week, whereas that of large BDNF-immunoreactive neurons decreased at 2 week when compared with those in the contralateral side. The intensity of immunoreactivity of each neuron was lower in the ipsilateral than in the contralateral DRG. 3) In the spinal cord, the Bennett and Chung model groups showed a markedly increased BDNF-immunoreactivity in axonal fibers of both superficial and deeper laminae. The present study demonstrates that peripheral nerve injury in neuropathic models altered the BDNF expression in the DRG and spinal cord. This may suggest important roles of BDNF in sensory abnormalities after nerve injury and in protecting the large-sized neurons in the damaged DRG.

• Journal of the speleological society of Korea
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• no.5
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• pp.96-106
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• 1997

The reduction of cave survey data is an essentially straightforward but repetitive mathematical task which can be carried out to advantage using virtually any type of computer from a programmable calculator upwards. The obvious benefits are speed and accuracy in reducing and adjusting the raw data to obtain the x,y,z coordinates (eastings, northings and elevations) of the surveyed points. Additionally, depending on the functionality of the software (program) and power of the hardware (computer), the user may be able to build up a data base of surveys, plot out on paper scaled plans and elecations of the cave and possibly even see a three-dimensional model of the cave, in perspective or some other projection, as an aid to understanding the spatial relationships of cave passages.(omitted)

• Mycobiology
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• v.45 no.4
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• pp.233-239
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• 2017

Drosophila melanogaster is a useful model organism that offers essential insights into developmental and cellular processes shared with humans, which has been adapted for large scale analysis of medically important microbes and to test the toxicity of heavy metals, industrial solvents and other poisonous substances. We here give a brief review of the use of the Drosophila model in medical mycology, discuss the volatile organic compounds (VOCs) produced by the opportunistic human pathogen, Aspergillus fumigatus, and give a brief summary of what is known about the toxicity of some common fungal VOCs. Further, we discuss the use of VOC detection as an indirect indicator of fungal growth, including for early diagnosis of aspergillosis. Finally, we hypothesize that D. melanogaster has promise for investigating the role of VOCs synthesized by A. fumigatus as possible virulence factors.

• ETRI Journal
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• v.46 no.2
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• pp.250-262
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• 2024

Air-writing recognition is relevant in areas such as natural human-computer interaction, augmented reality, and virtual reality. A trajectory is the most natural way to represent air writing. We analyze the recognition accuracy of words written in air considering five features, namely, writing direction, curvature, trajectory, orthocenter, and ellipsoid, as well as different parameters of a hidden Markov model classifier. Experiments were performed on two representative datasets, whose sample trajectories were collected using a Leap Motion Controller from a fingertip performing air writing. Dataset D₁ contains 840 English words from 21 classes, and dataset D₂ contains 1600 English words from 40 classes. A genetic algorithm was combined with a hidden Markov model classifier to obtain the best subset of features. Combination ftrajectory, orthocenter, writing direction, curvatureg provided the best feature set, achieving recognition accuracies on datasets D₁ and D₂ of 98.81% and 83.58%, respectively.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.205-208
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• 2002

Numerous studies have been performed to develop an analytical model that can predict the reflection of regular or irregular waves from a perforated-wall caisson breakwater. Though such irregular wave models as Suh et at. (2001) become available, regular wave models are still in extensive use because of their simplicity. In the present study, using the regular wave model of Fuggazza and Natale(1992), the reflection of irregular waves from a perforated-wall caisson breakwater was calculated in several different methods. First, the regular wave model was re-validated by the hydraulic model tests. Though the model somewhat over-predicted the reflection coefficients at larger values and under-predicted them at smaller values, overall agreement was pretty good between calculation and measurement. Then, the regular wave model was applied to calculate the irregular wave reflection in the experiments of Suh et at.(2001) and Bennett et al. (1992). In applying the regular wave model to irregular wave reflection, several different methods were used. The results showed that it is the most reasonable to use the regular wave model repeatedly for each frequency component of the irregular wave specuum with the root-mean-squared wave height for all the frequencies .

• Computers and Concrete
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• v.1 no.3
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• pp.261-284
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• 2004

Two enhancements to a recently developed plastic-damage-contact model for concrete are presented. The model itself, which uses planes of degradation that can undergo damage and separation but that can regain contact according to a contact law, is described. The first enhancement is a new damage evolution function which provides a completely smooth transition from the undamaged to the damaged state and from pre-peak to post-peak regions. The second is an improved contact function that governs the potential degree of contact with increasing opening on a crack plane. The use of a damage evolution function with a pre-peak has implications for the consistent tangent matrix/stress recovery algorithm developed for the model implementation, and amendments to this algorithm to accommodate the new function are described. A series of unpublished experimental tests on notched specimens undertaken in Cardiff in the mid 1990s are then described. These include notched beam tests as well as prismatic and cylindrical torsion tests. The tests are then considered in three dimensional finite element analyses using the modified Craft model implemented in the finite element program LUSAS. Comparisons between experimental and numerical data show reasonable agreement except that the numerical simulations do not fully describe the latter stages of the softening responses for the torsion examples. Finally, it is concluded that the torsion tests described provide useful benchmark examples for the validation of three-dimensional numerical models for concrete.

• Nuclear Engineering and Technology
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• v.46 no.5
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• pp.619-632
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• 2014

The Best Estimate Plus Uncertainty (BEPU) method has been widely used to evaluate the uncertainty of a best-estimate thermal hydraulic system code against a figure of merit. This uncertainty is typically evaluated based on the physical model's uncertainties determined by expert judgment. This paper introduces the application of data assimilation methodology to determine the uncertainty bands of the physical models, e.g., the mean value and standard deviation of the parameters, based upon the statistical approach rather than expert judgment. Data assimilation suggests a mathematical methodology for the best estimate bias and the uncertainties of the physical models which optimize the system response following the calibration of model parameters and responses. The mathematical approaches include deterministic and probabilistic methods of data assimilation to solve both linear and nonlinear problems with the a posteriori distribution of parameters derived based on Bayes' theorem. The inverse problem was solved analytically to obtain the mean value and standard deviation of the parameters assuming Gaussian distributions for the parameters and responses, and a sampling method was utilized to illustrate the non-Gaussian a posteriori distributions of parameters. SPACE is used to demonstrate the data assimilation method by determining the bias and the uncertainty bands of the physical models employing Bennett's heated tube test data and Becker's post critical heat flux experimental data. Based on the results of the data assimilation process, the major sources of the modeling uncertainties were identified for further model development.

• The Journal of the Korea Contents Association
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• v.13 no.12
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• pp.1069-1078
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• 2013

The paper is about teaching culture in a language learning. There are many teachers who are afraid of teaching foreign language with culture. They are delighted to teach politics, economics, history, art and literature as objective culture. But they are hesitant to teach subjective culture which is connected with a communication competency. The paper suggests three stages to instruct culture in a schoolroom. The first stage, it is growing out of the self-centered view. The second step, be developing self-consciousness through comparing mother culture with target culture. The last stage, it has to response to appropriately target culture. The teaching materials for the model suggested are two movies. Because the cultural aspects in the moves are subjective culture, so it has something in common with target cultural situations in a language learning. This method which is teaching culture in a the language learning has the advantage of being easy to teachers and learners. Most students like to watch a movie. The teaching material is The Chronicles of Narnia : The Lion, the Witch and The Wardrobe와 Guess Who?. I hope that this suggestion for cultural teaching is helpful for understanding each other.