• Title/Summary/Keyword: Behavioral tests

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Behavioral Toxicity of Cd-Treated Oryzias Latipes Using Computer-Automated Video Tracking System (자동영상추적장치를 이용한 카드뮴 처리 Oryzias latipes의 행위독성연구)

  • 류지성;이철우;최필선;최성수;류홍일;이길철;정규혁;박광식
    • Environmental Analysis Health and Toxicology
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    • v.14 no.4
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    • pp.217-222
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    • 1999
  • Changes in certain fish behaviors are known to be very sensitive indicators of sublethal exposure to environmental contaminants. Therefore, behavioral toxicity tests, if properly designed, can be very useful to assess the influence of hazardous chemicals on fish. However, quantitative analysis of xenobiotic-mediated changes in locomotor behavior in fishes are rare, due mainly to the methodological difficulties. In general, fish movement has been known to be hypertrophic or hypotrophic according to the chemicals. As a study of fish behavioral toxicities, we qualified the swimming movement of Oryzias latipes using computer-automated video tracking system. Oryzias latipes was exposed to cadmium of 128 mg/L for 1 hour in a limited aquaria, then the total swimming distance, the average swimming velocity, the histogram of turning angles, and the turning frequency were analyzed. Fish treated with cadmium showed decreased swimming activities, decreased velocity, and decreased turning frequency, which means hypotrophic activity. From these results, the computer-automated video tracking system of this study seems to be a good tool for the evaluation of the potential ecotoxicological studies.

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The Effects of Cognitive-Behavioral Group Counseling Program for Social Problem-Solving and Career Decision-Making Self-Efficacy in Incoming University Freshman (대학신입생의 사회적 문제해결력과 진로결정효능감 향상을 위한 인지행동집단상담 프로그램의 개발 및 효과)

  • Kim, Jung-Min;Park, Jun-Hee;Na, Yoon-Jung
    • Journal of Families and Better Life
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    • v.27 no.5
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    • pp.69-76
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    • 2009
  • This study aimed to develop cognitive-behavioral group counseling program for social problem-solving and career decision-making self-efficacy in incoming university freshman and to examine its efficacy through pre- and post-test. The program included cognitive restructuring, problem-solving and social skill training. The program consisted of 12 weekly sessions, approximately 1.5~2 hours in duration. Pre- and post-tests were administered to both a treatment group(n=48) and a control group(n=48). The collected data were statistically analyzed through ANCOVA. The main results of the study were as follows : The students in the treatment group showed a significant increase in both social problem-solving and career decision-making self-efficacy in comparison with those in the control group.

The Specification of Evaluative Objectives and Selection of Behavioral Elements for Measuring Science Inquiry Skills of University Competency Tests (대학(大學) 수학(修學) 용력(龍力) 의험(議驗)의 자연과학(自然科學) 탐구(探究) 능력(能力) 평가(評價)를 위(爲)한 행동(行動) 요소(要素)의 추출(抽出)과 평가(評價) 목표(目標)의 상세화(詳細化) 연구(硏究) II)

  • Woo, Jong-Ok;Lee, Kyung-Hoon;Lee, Hang-Ro
    • Journal of The Korean Association For Science Education
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    • v.12 no.2
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    • pp.81-95
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    • 1992
  • The purpose of the study is to specify the evaluative objectives of science process skills and to serve as an evaluative criterion for the development of university competency test. The followings are the results of this study. (l) Five steps as a teaching and learning model of science are suggested for the improvement of science inquiry skills. (2) Three dimensional taxomony was presented to evaluate the science process skills of university competency test. (3) Sixteen behavioral elements were selected from the science process model and defined operationally. (4) 146 evaluative objectives were specified according to each behavioral element based on the results presented above, the science inquiry model and the evaluative objectives wilt be contributed to teaching and learning strategies for the improvement of science process skills including basic concepts and contents, and problematic situation in science.

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Scolopendra Pharmacopuncture Ameliorates Behavioral Despair in Mice Stressed by Chronic Restraint

  • Choi, Yu-Jin;Lee, Hwa-Young;Kim, Yunna;Cho, Seung-Hun
    • Journal of Pharmacopuncture
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    • v.20 no.4
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    • pp.257-264
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    • 2017
  • Introduction: Pharmacopuncture, which combines acupuncture with herbal medicine, is one of the newly developed acupuncture techniques that has recently been put into use. The possible mechanisms of scolopendra pharmacopuncture, as well as its potential effects on depressive symptoms, were investigated in this study by using a mouse model of chronic immobilization stress (CIS). Methods: C57BL/6 male mice were randomly assigned into three groups: mice not stressed with restraint and injected with distilled water, mice stressed with restraint and injected with distilled water, and mice stressed with restraint injected with scolopendra pharmacopuncture at a cervical site. Behavioral tests (an open field test, tail suspension test, and forced swimming test) were carried out after two weeks of CIS and injection treatments. The expression levels of glial fibrillary acidic protein (GFAP) in the hippocampus were determined by using western blot and immunohistochemistry analyses. Results: Mice exposed to CIS showed decreased behavioral activity, while scolopendra pharmacopuncture treatment significantly protected against the depressive-like behaviors induced by CIS. Moreover, scolopendra pharmacopuncture treatment increased GFAP protein levels in the hippocampi of the mice stressed by chronic immobilization. Conclusion: Scolopendra pharmacopuncture has an ameliorating effect on depressive behavior, which is partially mediated through protection against glial loss in the hippocampus.

Influence of clozapine on neurodevelopmental protein expression and behavioral patterns in animal model of psychiatric disorder induced by low-level of lead

  • Lee, Hwayoung;Lee, Minyoung;Kim, Hyung-Ki;Kim, Young Ock;Kwon, Jun-Tack;Kim, Hak-Jae
    • The Korean Journal of Physiology and Pharmacology
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    • v.23 no.6
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    • pp.467-474
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    • 2019
  • Exposure to lead during pregnancy is a risk factor for the development of psychiatric disorders in the offspring. In this study, we investigated whether exposure to low levels of lead acetate (0.2%) in drinking water during pregnancy and lactation causes behavioral impairment and affects the expression of proteins associated with neurodevelopment. Lead exposure altered several parameters in rat offspring compared with those unexposed in open-field, social interaction, and pre-pulse inhibition tests. These parameters were restored to normal levels after clozapine treatment. Western blot and immunohistochemical analyses of the hippocampus revealed that several neurodevelopmental proteins were downregulated in lead-exposed rats. The expression was normalized after clozapine treatment (5 mg/kg/day, postnatal day 35-56). These findings demonstrate that downregulation of several proteins in lead-exposed rats affected subsequent behavioral changes. Our results suggest that lead exposure in early life may induce psychiatric disorders and treatment with antipsychotics such as clozapine may reduce their incidence.

Determinants to Behavioral Intentions of Job Recruiters to Distribute to E-Recruitment Systems

  • NGUYEN, Nhu-Ty
    • Journal of Distribution Science
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    • v.19 no.11
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    • pp.91-98
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    • 2021
  • Purpose: With the interest and ability in recruitment, it is totally worthy to discover how is labor market developed in Vietnam since the existence of the Internet. Considering employers as well as recruiters similar to jobseekers in term of technology adoption of job distribution, they should be treated fairly while performing their scopes of work. This paper aims to explore how employers perceive online recruiting platform as a supportive system, and this is to find out contributions of external factors regarding Job Boards behavioral intention to use. Research design, data and methodology: Conceptual framework tests the hypotheses involving in recruitment websites. Results: The results suggest that Board of Directors (BoD) or direct middle managers need to pay more attention on how their workforce performs through various channels of recruitment - both formal and informal, such as Linkedin or Facebook rather than a few compulsory job boards - no longer being accessed with high performance expectancy. However, the technology adaptation of recruitment is still a controversial issue due to its access to privacy of users. Conclusion: Therefore, employers should be more careful on how their personal contacts are going to be delivering without consent. Secondly, keeping systems up to date and "connected" is essential for both employees and employers.

Evaluating Staircase Safety Using BIM-based Virtual Simulation: Focusing on the Elderly in the Republic of Korea

  • Yang, Hyuncheul;Jeong, Kwangbok;Kim, Sohyun;Lee, Jaewook
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.1146-1153
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    • 2022
  • As the population is aging, accidents involving elderly people are also increasing (2014:11,667 persons; 2018: 11,797 persons). In the case of the elderly population, falling accidents are the primary direct or indirect causes of death; in particular, they face an elevated risk of staircase falls. This study proposes a method of evaluating the safety of staircases using Building Information Modeling (BIM)-based virtual simulation. By making a virtual user with the behavioral characteristics of the elderly respond to a staircase in a BIM model, its safety performance can be evaluated. The evaluation criteria were derived from regulations, elements, and characteristics relevant to the safety of staircases. To validate the proposed method, safety evaluation tests were simulated on actual staircases. The evaluation result of the test simulation shows the safety scores of 1.97 points for the elderly user and 2.95 points for the average male adult user against a required safety score of a minimum of 2 points. That is, safety is relative to users as the safety of the same staircase can be different depending upon the different behavioral characteristics of users. The study suggests that the risk of staircase-related fall accidents to the elderly can be reduced by improving staircase designs through the proposed method.

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Comprehensive Cross-sectional Study of Sarcopenia in Young Korean Women: Assessing Body Dimensions, Clinical Indicators, and Behavioral Traits for Hazardous Components and Proportional Analysis

  • Jongseok Hwang;Na-Hyung Kim
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.4
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    • pp.57-66
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    • 2023
  • PURPOSE: This research investigated clinical hazardous components and analyzed the proportion of sarcopenia among young Korean women. METHODS: The cross-sectional study included 1,236 women aged 20 to 29 years, categorized into two groups according to their skeletal muscle mass index (SMI). Of these, 20 participants were placed in the sarcopenia group, while 1,216 were included in the normal group. The analysis involved hazardous components including body dimensions, clinical indicators, and behavioral trait variables: height, weight, body mass index, waist circumference, skeletal muscle mass index, systolic and diastolic blood pressure, blood laboratory tests assessing fasting glucose, triglycerides, total cholesterol, as well as smoking habits and alcohol consumption. Complex sampling analysis was used to analyze the proportion and hazardous components of sarcopenia. RESULTS: The proportion of sarcopenia was at 1.76% (95% of CI: 1.08-2.83). Anthropometric measurements, such as height, BMI, and WC, exhibited significant differences between the groups (p < .05). However, there was no significant difference in weight (p > .05) between the two groups. Among the clinical indicators, SBP, DBP, FBG, serum triglycerides, and total TC found to be significant hazardous components for sarcopenia within both groups (p < .05). Smoking status as a behavioral trait was significant as well (p < .05), unlike alcohol consumption (p > .05). CONCLUSION: This study discerned both the proportion of sarcopenia and the hazardous components associated with it among community-dwelling women of a young age.

A Case Study of Sandplay Therapy in a College Student with Symptoms of Post-Traumatic Stress Disorder (외상 후 스트레스 장애 증상을 보이는 대학생의 모래놀이치료 사례연구)

  • Jung, Woo-Hee
    • Journal of the Korean Home Economics Association
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    • v.48 no.3
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    • pp.55-69
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    • 2010
  • A college student who exhibited several post traumatic stress disorder (PTSD) symptoms was used as a case study in order to investigate the therapeutic effects of sandplay therapy for PTSD sufferers. In total, 27 sessions of the sandplay treatment program were used to conduct psychological tests before and after the sessions. Any changes in the manner of expressions on the sand box during the treatment, and the results of pre and post psychological tests on aspects of depression, anxiety and interrelationships were analyzed. Overall results showed that the subject exhibited progressive behavioral improvement and signs of recovery. Psychological tests revealed reduced levels of depression and anxiety, and improved interrelationship scores. In conclusion, sandplay therapy does exhibit positive benefits as an effective treatment modality for PTSD in adolescents and young adults.

Protective Effects of Stephania tetrandra against Focal Cerebral Ischemic Damage by Middle Cerebral Artery Occlusion in Rats (방기가 백서 중대뇌동맥 폐쇄에 의한 국소뇌허혈손상에 미치는 보호효과)

  • 정혁상;이현삼;원란;강철훈;손낙원
    • The Journal of Korean Medicine
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    • v.22 no.1
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    • pp.10-21
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    • 2001
  • Objective : This study was performed to investigate the protective effect of Stephania tetrandra(ST) against ischemic brain damage after a middle cerebral artery(MCA) occlusion. The effect was evaluated using histological tests, neurobehavioral tests, and biochemical tests. Methods : Rats(Sprague-Dawley) were divided into four groups : sham operated group, MCA occluded group, post MCA occlusion Stephania tetrandra administrated (7.6mg/l00g) group, and normal group. The MCA was occluded by intraluminal method. Stephania tetrandra was administrated orally twice at 1 and 4 hours after MCA occlusion. The neurobehavioral test was performed at 3, 6, 9 and 24 hours after MCA occlusion by posture reflex test and swimming behavioral test. All groups were sacrificed then. The brain tissues were stained with 2% triphenyl tetrazolium chloride(TTC) or 1 % cresyl violet solution, to examine infarct size, volume and cell number. Tumor necrosis $factor-{\alpha}$ level was measured from sera using Enzyme-Linked Immunoabsorbent Assay(ELISA). The mRNA expression level of inflammatory cytokines and related receptor type I and II, $IL-1{\beta}$, IL-6, and IL-10 6hours after MCA occlusion were also studied by reverse transcriptase polymerase chain reaction(RTPCR). Results : The results showed that : Stephania tetrandra (1) reduced infarct size and total infarct volume by 52.2% compared to the control group; (2) attenuated significantly in neuronal death, which was shown by a decrease in cell number(P<0.01) and size(P<0.01) in the boundary area of the infarction; (3) significantly reduced serum $TNF-{\alpha}$ level, and increased the mRNA level of IL-10 in the cortex region(P<0.01). However, there was no significant effect on motor deficit in swimming behavioral test. Conclusions : In conclusion, Stephania tetrandra has protective effects against ischemic brain damage at the early stage of ischemia.

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