• Title/Summary/Keyword: Behavioral states

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NMDA Receptor Activation Mediates Neuropathic Pain States Induced by Calcium Channel α2δ1 Subunit (신경병증성 통증과정의 NMDA 수용체 활성과 칼슘통로 α2δ1 Subunit의 영향)

  • Yu, Soo Bong;Lim, Young Soo;Kim, Doo Sik
    • The Korean Journal of Pain
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    • v.22 no.3
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    • pp.210-215
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    • 2009
  • Background: Several studies have indicated that a nerve injury enhances the expression of the voltage-gated calcium channel ${\alpha}2{\delta}1$ subunit (Cav ${\alpha}2{\delta}1$) in sensory neurons and the dorsal spinal cord. This study examined whether NMDA receptor activation is essential for Cav ${\alpha}2{\delta}1$-mediated tactile allodynia in Cav ${\alpha}2{\delta}1$ overexpressing transgenic mice and L5/6 spinal nerve ligated rats (SNL). These two models show similar Cav ${\alpha}2{\delta}1$ upregulation and behavioral hypersensitivity, without and with the presence of other injury factors, respectively. Methods: The transgenic (TG) mice were generated as described elsewhere (Feng et al., 2000). The left L5/6 spinal nerves in the Harlan Sprague Dawley rats were ligated tightly (SNL) to induce neuropathic pain, as described by Kim et al. (1992). Memantine 2 mg/kg (10 ul) was injected directly into the L5/6 spinal region followed by $10{\mu}l$ saline. Tactile allodynia was tested for any mechanical hypersensitivity. Results: The tactile allodynia in the SNL rats could be reversed by an intrathecal injection of memantine 2 mg/kg at 1.5 hours. The tactile allodynia in the Cav ${\alpha}2{\delta}1$ over-expressing TG mice could be reversed by an intrathecal injection of memantine 2 mg/kg at 1.5, 2.0 and 2.5 hours. Conclusions: The behavioral hypersensitivity was similar in the TG mice and nerve injury pain model, supporting the hypothesis that elevated Cav ${\alpha}2{\delta}1$ mediates similar pathways that underlie the pain states in both models. The selective activation of spinal NMDA receptors plays a key role in mediating the pain states in both the nerve-injury rats and TG mice.

Male Hynobius leechii (Amphibia: Hynobiidae) Discriminate Female Reproductive States Based on Chemical Cues

  • Park, Dae-Sik;Sung, Ha-Cheol
    • Animal cells and systems
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    • v.10 no.3
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    • pp.137-143
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    • 2006
  • A series of no-choice olfactory response tests using water pre-conditioned with females, with intact and surgically removed ventral glands, at various reproductive states were conducted to determine whether male Hynobius leechii discriminates among females in different reproductive states based on chemical cues. Similarly, ventral gland extracts were tested, and ventral glands were examined histologically. Males’ responses to putative odors of females in four (ovulating, ovulated, ovipositing, and oviposited) reproductive states were independently measured by: i) the latency time to initiate male behavioral response, ii) the arrival time at a fixed point of putative odor source, and iii) the staying time close to the odor point source. Male salamanders showed significant olfactory responses to recently ovulated and ovipositing female odors by quickly arriving at odor sources and staying longer at the origin of the source, but the olfactory responses to the earlier staged ovulating females and the later stage of already oviposited females were not different from controls. Olfactory responses of test males to water preconditioned by intact females or females with ventral glands excised were not different. In addition, ventral gland extracts did not induce significant olfactory responses of test males although the lumens of alveoli in ventral glands of oviposited females were smaller than those of ovulated females. These results indicate that male H. leechii recognizes ovulated and ovipositing females based on chemical cues released but not from the ventral glands.

Behavioral characteristics of a chondrostean sturgeon species Acipenser baerii prelarvae in response to different environmental light intensities in a diel photoperiodic cycle

  • Kim, Eun Jeong;Park, Chulhong;Nam, Yoon Kwon
    • Journal of Animal Reproduction and Biotechnology
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    • v.35 no.3
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    • pp.245-257
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    • 2020
  • Behavioral response to a diel photoperiodicity (500 lx for 16 h, 5 lx for 4 h and < 0.5 lx for 4 h) and phototactic characteristics in dark conditions were examined with Siberian sturgeon Acipenser baerii (Chondrostei, Actinopterygii) prelarvae. Siberian sturgeon prelarvae represented both qualitative and quantitative changes in their behavioral patterns according to different light intensities in a diel photoperiodicity. Under daylight conditions (500 lx), prelarvae displayed saltatory changes of behavioral features with ages (Day 0-Day 9) in a general order of swimming-up/drifting, swimming in the upper water column, benthic swimming with rheotaxis, schooling and post-schooling behavior. Compared to daylight conditions, prelarvae tended to show more benthic performances and quantitative reductions of schooling and post-schooling behaviors under dimlight conditions (5 lx). Under dark conditions (< 0.5 lx), prelarvae exhibited a fairly uniform behavioral pattern characterized by the benthic swimming across the bottom of the tank. From phototaxis tests under dark conditions, navigational responses of prelarvae to a spotlight illumination were quantitatively changed as their ages increased. The phototactic responses reached the peak on Day 2, continued until Day 4, and then gradually decreased until Day 8. A partial recovery of positive phototaxis was observed on Day 9. Data from this study suggest that the diel light cycle as well as the light intensity of each interval in the cycle should be considered as important components of a practical guide for evaluating fitness and developmental states of artificially propagated Siberian sturgeon prelarvae.

Social Isolation Selectively Increases Anxiety in Mice without Affecting Depression-like Behavior

  • Kwak, Chul-Jung;Lee, Sue-Hyun;Kaang, Bong-Kiun
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.5
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    • pp.357-360
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    • 2009
  • It is hypothesized that a number of environmental factors affect animals' behavior. Without controlling these variables, it is very hard for researchers to get not only reliable, but replicable data from various behavioral experiments testing animals' cognitive as well as emotional functions. For example, laboratory mice which had restricted environment showed different synaptic potentiation properties with wild mice (Zhao MG et al., 2009). While performing behavioral experiments, however, it is sometimes inevitable that the researcher changes the animals' environments, as by switching the cages in which experimental animals are housed and separating animals raised together into small experimental groups. In this study, we investigated the effect of environmental changes on mice's emotional behaviors by socially isolating them or reducing the size of their cage. We found that social isolation selectively increases the animals' levels of anxiety, while leaving depression-like behaviors unchanged. On the other hand, alteration of the housing dimensions affected neither their anxiety levels nor their depression-like behaviors. These results suggest that environmental variables may have a prominent impact on experimental animals' emotional behaviors and possibly their psychological states, leading to bias in the behavioral data produced from experiments.

Another Diagnostic Approach : An Introduction to Research Domain Criteria (RDoC) (새로운 진단적 접근법 : Research Domain Criteria(RDoC)의 소개)

  • Oh, Daeyoung
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.63-65
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    • 2013
  • The new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) is published by the American Psychiatric Association. The diagnostic systems for mental disorders have come under criticism for relying on presenting signs and symptoms with the result that they do not adequately reflect relevant neurobiological and behavioral systems. Finally, the National Institute of Mental Health (NIMH) in the United States has suggested the Research Domain Criteria (RDoC) to develop a research classification system based upon dimensions of neurobiology and behavioral aspect. The present review introduces the RDoC as a new reaseach framework.

An Application of Vroom's Expectancy Theory to Examine Bank Managers Motivation to Utilize an Expert System (Vroom의 Expectancy Theory에 의한 은행 매니저들의 전문가 시스템 사용에 대한 모티베이션 분석)

  • Sim, Jeong-Pil;Lee, Yong-Jin
    • Asia pacific journal of information systems
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    • v.6 no.1
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    • pp.75-108
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    • 1996
  • Expert Systems (ES) have been successfully applied to bank loan decisions. However, with regard to bank loan decisions, most loan officers approach the acquisition of an ES with apprehension, which implies that organizational resources devoted to the development and implementation of ES may have been wasted or misused. Because the primary cause of the users resistance to use ES are more significantly related to the behavioral elements rather than technical elements, applying appropriate behavioral theory to the well representative sample group of the whole bank loan officers in the United States with a very accurate measurement tool can provide some clues for developing successful ES for bank loan officers. In this study : 1) Vroom's (1964) expectancy theory was selected to explain bank loan managers' motivation to use an ES ; and 2) the ANN model's prediction power to estimate bank loan officers' motivation levels of using an ES was examined.

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Effect of Feet Cooling and Feet Warming on the Behavioral Temperature Regulation (족부의 냉각과 가온이 행동성 체온조절에 미치는 영향)

  • Jeong, Woon-Seon
    • The Korean Journal of Community Living Science
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    • v.18 no.4
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    • pp.681-686
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    • 2007
  • This study was conducted to investigate the effects of the thermally different states of human feet on temperature regulation in winter season. Five healthy female students of age 20 volunteered as subjects to participate in the study. Physiological responses such as rectal temperature and skin temperatures as well as subjective responses of thermal comfort and thermal sensation were observed. Preferred clothing and preferred temperature were also evaluated in terms of behavioral temperature regulation. The results obtained through the experiment were statistically analyzed using paired t test. Rectal temperature was decreased greater (p<.01) and mean skin temperature was maintained higher (p<.01) in feet wanning than in feet cooling. Results of preferred clothing were coincident with those of general thermal sensation. There was a higher tendency to prefer temperature in feet wanning than feet cooling in the morning. It was concluded that keeping feet skin temperature lower in the early morning and higher in the late evening would be effective in terms of regulating circadian rhythm of core temperature.

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The Evolution of Community Nutrition in the U.S.

  • Gillespie, Ardyth M.H.
    • Journal of Community Nutrition
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    • v.5 no.4
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    • pp.195-208
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    • 2003
  • Drawing from journal articles, community nutrition textbooks, government documents, national conference reports, the author's own work in community programming, and discussions with practicing Community Nutritionists, this article illuminates the scope and character of community nutrition in the United States. It traces the roots of community nutrition in home economics, nutrition, education, communication, social and behavioral sciences, and describes the evolution of theory. And finally it suggests issues to be addressed by community nutrition researchers and practitioners through collaborations that integrate perspectives within community nutrition and strategically cross disciplinary boundaries. These include: 1) theory development and application in research and practice within philosophically consistent perspectives; 2) methodological development (qualitative and quantitative) drawing from the social and behavioral sciences that apply to community nutrition; 3) taking a long view of community nutrition and recognizing that change requires integrated efforts over long periods of time; 4) engaging community stakeholders in research as well as program planning and 5) engaging with community nutritionists from other countries for cross-cultural research and conceptualization. This journal and the Korean Society for Community Nutrition, as the only journal and society expressly devoted to community nutrition, would be the best context for such collaborations.

A Review of Public Datasets for Keystroke-based Behavior Analysis

  • Kolmogortseva Karina;Soo-Hyung Kim;Aera Kim
    • Smart Media Journal
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    • v.13 no.7
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    • pp.18-26
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    • 2024
  • One of the newest trends in AI is emotion recognition utilizing keystroke dynamics, which leverages biometric data to identify users and assess emotional states. This work offers a comparison of four datasets that are frequently used to research keystroke dynamics: BB-MAS, Buffalo, Clarkson II, and CMU. The datasets contain different types of data, both behavioral and physiological biometric data that was gathered in a range of environments, from controlled labs to real work environments. Considering the benefits and drawbacks of each dataset, paying particular attention to how well it can be used for tasks like emotion recognition and behavioral analysis. Our findings demonstrate how user attributes, task circumstances, and ambient elements affect typing behavior. This comparative analysis aims to guide future research and development of applications for emotion detection and biometrics, emphasizing the importance of collecting diverse data and the possibility of integrating keystroke dynamics with other biometric measurements.

A Comparative Analysis of Customer Choice and Satisfaction Factors among Three Types of Coffee Shops (커피 전문점 선택요인과 만족도에 관한 비교 연구)

  • Lee, Yang-Kyu;Park, Sang-Youn;Hwang, Il-Young
    • Journal of Distribution Science
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    • v.12 no.2
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    • pp.49-57
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    • 2014
  • Purpose - Theorists and researchers in the area of customer satisfaction generally agree that product satisfaction intervenes between expectancy disconfirmation and various post-purchase cognitive states including attitude and behavioral intention. Studies in a variety of settings have supported the effect of expectation and its disconfirmation on satisfaction, but only a small number of studies address the cognitive consequences of satisfaction decisions and none report data on choice processes such as brand selection. This study examines the influence of satisfaction and its determinants on behavioral intention and product preference in eight coffee shops across the country. Generally it was found in both overall and summed attribute analyses that satisfaction was a function of expectation and disconfirmation, that intention was a function of satisfaction, and that preference was influenced by satisfaction and disconfirmation, the latter having the greater effect. Research design, data, and methodology - The main objective of this study was to assess the dimensions of consumer selection and satisfaction in choosing a coffee shop. In order to achieve this objective, a study of coffee shops across the country was conducted. This study comprised in-depth questionnaires distributed to coffee shop customers. A survey was conducted from September 1, 2011 to September 30, 2011, involving franchise coffee shop, independently owned coffee shop, and roastery coffee shop customers. Results - Hypothesis 1-1, which states that coffee shop choice attributes differ based on the type of coffee shop, is accepted. It has a significance level of 0.05, according to choosing properties of coffee shop by convenience of transportation, varieties of beans, residence of the owner (manager), information, and relationships. Hypothesis 1-2, which states that satisfaction with the choice factor differs depending on the type of coffee shops, is accepted. The P-values for cleanliness and varieties of beans were 0.04 and 0.00, respectively, and have a significance level of 0.05, according to the satisfaction with the chosen coffee shop. Hypothesis 2-1, which states that the importance of the choice attributes in coffee shop selections differs based on the demographic characteristics of the customers, is accepted. According to the t-test result, convenience of parking and residence of the owner (manager) are significant. Hypothesis 2-2, which states that satisfaction with the choice factor will differ depending of the type of coffee shop, is accepted. According to the t-test result, convenience of parking and residence of the owner (manager) are significant. Conclusions - This study has shown that intention to revisit a certain shop is most likely correlated to satisfaction in all cases. In order to offer subsequent developments for coffee shops, this study also identifies relations between customer satisfaction and selection by finding significant factors. In order to maximize customers' satisfaction, coffee shops should analyze and satisfy customers' needs and wants in terms of coffee service. While the findings do not generalize beyond the mall sampling procedure used here, we have hopefully identified a close approximation of the process of satisfaction decisions used by consumers generally.