• Journal of the Korean GEO-environmental Society
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• v.21 no.5
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• pp.5-11
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• 2020

Outliers detection and elimination included in field monitoring datum are essential for effective foundation of unusual movement, long and short range forecast of stability and future behavior to various structures. Integrated outlier analysis system for assessing long term time series data was developed in this study. Outlier analysis could be conducted in two step of primary analysis targeted at single dataset and second multi datasets analysis using synthesis value. Integrated outlier analysis system presents basic information for evaluating stability and predicting movement of structure combined with real-time safety management platform. Field application results showed increased correlation between synthesis value including similar sort of sensor showing constant trend and each single dataset. Various monitoring data in case of showing different trend can be used to analyse outlier through correlation-weighted value.

• Macromolecular Research
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• v.16 no.8
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• pp.695-703
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• 2008

Nanoparticles have tremendous potential in cancer prevention, detection and augmenting existing treatments. They can target tumors, carry imaging capability to document the presence of tumors, sense pathophysiological defects in tumor cells, deliver therapeutic genes or drugs based on the tumor characteristics, respond to external triggers to release an appropriate agent, document the tumor response, and identify the residual tumor cells. Nanoparticles < 30 nanometers in diameter show unexpected and unique properties. Furthermore, particles < 5 nanometers in size can easily penetrate cells as well as living tissues and organs. This study evaluated the safety of nano materials in a living body and the relationship between the living tissue and synthetic nano materials by examining the in-vitro cytotoxicity of poly(lactic-co-glycolic) acid (PLGA) nano-spheres and fluorescein isothiocynate(FITC)-labeled dendrimers as polymer nanoparticles. PLGA was chosen because it has been used extensively for biodegradable nanoparticles on account of its outstanding bio-compatibility and its acceptance as an FDA approved material. The dendrimer was chosen because it can carry a molecule that recognizes cancer cells, a therapeutic agent that can kill those cells, and a molecule that recognizes the signals of cell death. Cytotoxicity in L929 mouse fibroblasts was monitored using MTT assay. Microscopic observations were also carried out to observe cell growth. All assays yielded meaningful results and the PLGA nanoparticles showed less cytotoxicity than the dendrimer. These nano-particles ranged in size from 10 to 100 nm according to microscopy and spectroscopic methods.

• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.327-345
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• 2016

The purpose of this study was to carry out cognitive movement therapy program for children with affective and behavioral disorder based on neuro science, psychology, motor learning, muscle physiology, biomechanics, human motion analysis, movement control and to quantify characteristic of expression and gestures according to change of facial expression by emotional change. We could observe problematic expression of children with affective disorder, and could estimate the efficiency of application of movement therapy program by the face expression change of children with affective disorder. And it could be expected to accumulate data for early detection and therapy process of development disorder applying converged measurement and analytic method for human development by quantification of emotion and behavior therapy analysis, kinematic analysis. Therefore, the result of this study could be extendedly applied to the disabled, the elderly and the sick as well as children.

• Journal of agricultural medicine and community health
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• v.23 no.2
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• pp.215-227
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• 1998

To find health problems of Pohang city and to plan the activities to solve them in the situation of localization, the mortalities of the citizens in recent three years from 1994 to 1996 were analyzed from the notices and the certificates of death. The ratios of the notices with the certificates of death In the rural area of Pohang city were higher than those of whole country, the ratios of the urban area were lower than the respective ones, and the ratio differences between the rural and urban area were increasing. It may be that medical facilities are not within easy access of the rural inhabitants. especially in the rural south district with high population density. The proportional mortality indicators(PMI) were lower them those of whole country, much lower in male. So the health status of young aged males is relatively unsatisfactory. The urban inhabitants died in hospitals about two times more than the rural inhabitants and the differences were increasing. It may be that living and housing conditions and socio-cultural differences affected on the places of death. Because it is thought that death in hospitals will be growing at high speed, it is necessary to enlarge facilities fur funeral services. The age standardized mortalities were lower than those of whole country and age grouped mortalities were also the same. There were not any consistent and meaningful findings in the sex ratios of mortality according to the age groups or the calendar years. The mortalities by neoplasms and cardiovascular diseases according to the twenty one major causes of death were rapidly increased from the middle ages in both male and female. So it is important to plan the activities for early detection and health maintenance or promotion by behavior modifications. The leading causes of death were cardiovascular diseases, hypertensive diseases, and traffic accidents. And accidental drowning because of coastal area, liver diseases in male, and low respiratory tract diseases in female were the leading causes of death in part of age groups.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1583-1588
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• 2010

A single step fabrication process of carbon nanotube/Prussian Blue (CNT/PB) paste electrodes based on screen printing technology has been studied as an amperometric sensor for the determination of hydrogen peroxide and free chlorine. Compared to the classical carbon paste (CP) electrode, the CNT paste electrode greatly enhanced the response in the presence of hydrogen peroxide due to the electrocatalytic activity of the CNT. Based on the CNT/binder paste, PB was also incorporated into a network of CNT paste and characterized. The best electroanalytical properties of PB-mixed sensors to hydrogen peroxide were obtained with PB ratio of 10 wt % composition, which showed fast response time ($t_{90}{\leq}5$ s; 0.2 - 0.3 mM), low detection limit of 1.0 ${\mu}M$, good linear response in the range from $5.0{\times}10^{-5}$ - $1.0{\times}10^{-3}$ mol $L^{-1}$ ($r^2$ = 0.9998), and high sensitivity of -8.21 ${\mu}AmM^{-1}$. In order to confirm the enhanced electrochemical properties of CNT/PB electrode, the sensor was further applied for the determination of chlorine in water, which exhibited a linear response behavior in the range of 50 - 2000 ppb for chlorine with a slope of 1.10 ${\mu}Appm^{-1}$ ($r^2$ = 9971).

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.58-61
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• 2018

In Korea, current medical technology is the highest level in the world. As a result, many doctors have specialized knowledge of various disorders or diseases, and are proceeding in a better way. With such high medical technology, it is possible to increase the probability of success of surgery to provide high reliability to patients. Rehabilitation is also a form of medical treatment that reduces the side effects that occur after surgery that is done for quick cure. However, the situation in this section is slightly different. There are moves to develop rehabilitation devices and operations, but most of them are now dependent on foreign technology. Rehabilitation therapy, which we commonly know, is dominated by behavior. However, it is also a kind of rehabilitation to find out how much the patient's symptoms are improved or recovered. In this paper, we have studied the development of a program by using the Deeplearning method in order to detect the problem of the food swallowing operation by the severity.

• Journal of Convergence for Information Technology
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• v.10 no.8
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• pp.15-22
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• 2020

The 4th industrial revolution and the rapid change in the data environment revealed technical limitations in the existing relational database(RDB). As a new analysis method for unstructured data in all fields such as IDC/finance/insurance, interest in graph database(GDB) technology is increasing. The graph database is an efficient technique for expressing interlocked data and analyzing associations in a wide range of networks. This study extended the existing RDB to the GDB model and applied machine learning algorithms (pattern recognition, clustering, path distance, core extraction) to detect new abnormal signs. As a result of the performance analysis, it was confirmed that the performance of abnormal behavior(about 180 times or more) was greatly improved, and that it was possible to extract an abnormal symptom pattern after 5 steps that could not be analyzed by RDB.

• Bulletin of the Korean Chemical Society
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• v.30 no.1
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• pp.137-144
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• 2009

In this study, quantitative and pattern recognition analyses for the quality evaluation of Herba Epimedii using HPLC was developed. For quantitative analysis, five major bioactive constituents, hyperin, epimedin A, epimedin B, epimedin C, and icariin were determined. Analysis was carried out on Capcell pak $C_{18}$ column ($250{\time}4.6$ mm, 5 ${\mu}m$) with a mobile phase of mixture of acetonitrile and 0.1% formic acid, using UV detection at 270 nm. The linear behavior was observed over the investigated concentration range (2-50 ${\mu}g/mL;\;r_2\;>$ 0.99) for all analytes. The intraand inter-day precisions were lower than 4.3% (as a relative standard deviation, RSD) and accuracies between 95.1% and 104.4%. The HPLC analytical method for pattern recognition analysis was validated by repeated analysis of one reference sample. The RSD of intra- and inter-day variation of relative retention time (RRT) and relative peak area (RPA) of the 12 selected common peaks were below 0.8% and 4.7%, respectively. The developed methods were applied to analysis of twenty Herba Epimedii extract samples. Contents of hyperin, epimedin A, epimedin B, epimedin C, and icariin were calculated to be 0$\sim$0.79, 0.69$\sim$1.91, 0.93$\sim$9.58, 0.65$\sim$3.05, and 2.43$\sim$11.8 mg/g dried plant. Principal component analysis (PCA) showed that most samples were clustered together with the reference samples but several apart from the main cluster in the PC score plot, indicating differences in overall chemical composition between two clusters. The present study suggests that quantitative determination of marker compounds combined with pattern-recognition method can provide a comprehensive approach for the quality assessment of herbal medicines.

• Membrane and Water Treatment
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• v.7 no.3
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• pp.241-255
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• 2016

In this study, the treatability of arsenic (As) contaminated water by direct contact membrane distillation (DCMD) at different delta temperatures (${\Delta}T$) 30, 40 and $50^{\circ}C$ has been investigated. Two different pore sizes ($0.22{\mu}m$ and $0.45{\mu}m$) of hydrophobic membranes made of polyvinylidene fluoride (PVDF) were used. The membrane pore sizes, the operating temperatures, the feed solution As concentration and conductivity have been varied during the experimental tests to follow the removal efficiency and flux behavior. Both membranes tested had high removal efficiency of arsenite (As (III)) and arsenate (As (V)) and all permeates presented As concentration far lower than recommended $10{\mu}g/L$ of world health organization (WHO). As concentration was below detection limit in many permeates. Conductivity reduction efficiency was over 99% and the transmembrane flux (TMF) reached $19L/m^2.h$ at delta temperature (${\Delta}T$) of $50^{\circ}C$ with PVDF $0.45{\mu}m$ membrane. The experimental results also indicated that $0.45{\mu}m$ pore sizes PVDF membranes presented higher flux than $0.22{\mu}m$ pore sizes membranes. Regardless of all operating conditions, highest fluxes were observed at highest ${\Delta}T$ ($50^{\circ}C$).

• Journal of the Korea Society for Simulation
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• v.16 no.1
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• pp.31-37
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• 2007

The importance of NPC's role in computer games is increasing. An NPC must perform its tasks by perceiving obstacles and other characters and by moving through them. It has been proposed to plan a natural-looking path against fixed obstacles by using a generalized visibility graph. In this paper we develop the execution module for an NPC to move efficiently along the path planned on the generalized visibility graph. The planned path consists of line segments and arc segments, so we define steering behaviors such as linear behaviors, circular behaviors, and an arriving behavior for NPC's movements to be realistic and utilize them during execution. The execution module also includes the collision detection capability to be able to detect dynamic obstacles and uses a decision tree to react differently according to the detected obstacles. The execution module is tested through the simulation based on the example scenario in which an NPC interferes the other moving NPC.