• Archives of Pharmacal Research
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• 제23권4호
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• pp.367-373
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• 2000

Cholic acid, conjugated with amine-terminated poly(W-isopropylacrylamide) (abbreviated as CA/ATPNIPAAm), was synthesized by a N, N'-dicyclohexyl carbodiimide (DCC)-mediated coupling reaction. Self-assembled CA/ATPNIPAAm micelles were prepared by a diafiltration method in aqueous media. The CA/ATPNIPAAm micelles exhibited a lower critical solution temperature (LCST) at $31.5^{\circ}C$. Micelle sizes measured by photon correlation spectroscopy (PCS) were approximately 31.6 $\times$$\times$ 5.8 nm. The CA/ATPNIPAAm micelles were spherical and their thermal size transition was observed by transmission electron microscope (TEM). A fluorescence probe technique was used for determining the micelle formation behavior of CA/ATPNIPAAm in aqueous solutions using Pyrene as a hydrophobic Probe. The critical micelle concentration (CMC) was evaluated as $8.9{\times}0^{-2}$ g/L. A drug release study was performed using indomethacin (IN) as a hydrophobic model drug. The release kinetics of IN from the CA/ATPNIPAAm micelles revealed a thermo-sensitivity by the unique character of poly(N-isopropylacrylamide) i.e. the release rate was higher at $25^{\circ}C$ than at $37^{\circ}C$.

• 한국게임학회 논문지
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• 제6권4호
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• pp.79-87
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• 2006

본 논문은 기계학습 기법을 이용한 게임 캐릭터를 제어하는 엔진을 설계하고 구현하는 것을 제안한다. 제안된 엔진은 실제 게임에서 상황 데이터를 추출하여 지식 데이터로 사용하므로 지능 캐릭터의 행동 패턴을 게이머들이 쉽게 인식하지 못하는 장점이 있다. 이를 위하여 상황 데이터를 추출하여 학습하는 모듈과 임의의 상황 데이터에 대하여 최적의 상황 제어를 판단하는 시험 모듈을 개발하는 것을 제안하였다. 구현된 엔진은 FEAR에 이식되고 Quake2 게임에 적용되었다. 또한 개발된 엔진의 올바른 동작과 효율성을 위하여 다양한 실험을 하였다. 실험으로부터 개발된 엔진이 올바르게 동작할 뿐만 아니라 제한된 시간 내에 효율적으로 동작함을 알 수 있었다.

• Structural Engineering and Mechanics
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• 제56권3호
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• pp.491-506
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• 2015

Propagation of the generalized Rayleigh waves in an initially stressed elastic half-space covered by an elastic layer is investigated. It is assumed that the initial stresses are caused by the uniformly distributed normal compressional forces acting on the face surface of the covering layer. Two different cases where the compressional forces are "dead" and "follower" forces are considered. Three-dimensional linearized theory of elastic waves in initially stressed bodies in plane-strain state is employed and the elasticity relations of the materials of the constituents are described through the Murnaghan potential where the influence of the third order elastic constants is taken into consideration. The dispersion equation is derived and an algorithm is developed for numerical solution to this equation. Numerical results for the dispersion of the generalized Rayleigh waves on the influence of the initial stresses and on the influence of the character of the external compressional forces are presented and discussed. These investigations provide some theoretical foundations for study of the near-surface waves propagating in layered mechanical systems with a liquid upper layer, study of the structure of the soil of the bottom of the oceans or of the seas and study of the behavior of seismic surface waves propagating under the bottom of the oceans.

• 전기화학회지
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• 제2권4호
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• pp.209-212
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• 1999

H-형의 분리 셀을 사용하여 중성 및 실온의 온화한 조건에서 조절 전위법 음전극 반응에 의한 nitroarene화합물들의 환원 짝지음 반응으로 높은 수율의 azobenzene유도체를 합성하였다. Pb또는 Pt cathode와 Pt anode를 사용하여 메탄을 용액 하에서 cyclic voltammetry에 근거하여 각 반응의 최적의 반응 조건을 결정한 후 반응을 실행하였으며, 대부분의 경우 환원 짝지음 반응은 치환기의 성질과 위치에 영향을 받지 않고 높은 수율로 성공적인 결과를 얻을 수 있었다.

• 한국실내디자인학회논문집
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• 제5호
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• pp.59-65
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• 1995

This thesis focuses on a study of design science, which is of a disciplinary character. And the purpose of such a study is to suggest a new direction to develop aesthetics through an empirical research into environmental psychol-ogy, human behavior, design thought, and the visual qual-ity of environment. The author of this study, since recognizing the necessi-ty of understanding environmental aesthetics as well as the necessity of aesthetics, has done an elementary study of empirical aesthetes, and then obtained some facts as follows: First, it is possible to analyse the visual characteristics immanent in the interrelations between human and envi-ronment by means of applying both the information the-ory of formal perception and expressional value and the perceptual theory of ecology to environmental aesthetics. Second, formal aesthetics is a science about the form and structure and in the meantime, symbolic aesthetics is a science about the environmental patterns giving pleas-ure to mankind and its associative meanings. Accordingly it is same as providing some aesthetic value to the ob-ject of environment design to apply some empirical data of visual quality to environmental design. Through such a process, users are provided or delivered with diverse, visual effect. In conclusion, environmental aesthetics is worthwhile to study, and its purpose is that it, as a framework of use-ful knowledge to the creation of the environment superi-or in quality, be applied to design.

• ALGAE
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• 제28권4호
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• pp.307-330
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• 2013

The genus Cryptomonas is easily recognized by having two flagella, green brownish color, and a swaying behavior. They have relatively simple morphology, and limited diagnostic characters, which present a major difficulty in differentiating between species of the genus. To understand species delineation and phylogenetic relationships among Cryptomonas species, the nuclear-encoded internal transcribed spacer 2 (ITS2), partial large subunit (LSU) and small subunit ribosomal DNA (rDNA), and chloroplast-encoded psbA and LSU rDNA sequences were determined and used for phylogenetic analyses, using Bayesian and maximum likelihood methods. In addition, nuclear-encoded ITS2 sequences were predicted to secondary structures, and were used to determine nine species and four unidentified species from 47 strains. Sequences of helix I, II, and IIIb in ITS2 secondary structure were very useful for the identification of Cryptomonas species. However, the helix IV was the most variable region across species in alignment. The phylogenetic tree showed that fourteen species were monophyletic. However, some strains of C. obovata had chloroplasts with pyrenoid while others were without pyrenoid, which used as a key character in few species. Therefore, classification systems depending solely on morphological characters are inadequate, and require the use of molecular data.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 추계학술대회 논문집
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• pp.732-739
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• 2005

The determination of sound pressure radiated from periodic plate structures is fundamental in the estimation of noise level in aircraft fuselages or ship hull structures. As a robust approach to this problem, here a very general and comprehensive analytical model is developed for predicting the sound radiated by a vibrating plate stiffened by periodically spaced orthogonal symmetrical beams subjected to a sinusoidally time varying point load. In this these, we experiment with the numerical analysis using the space harmonic series and the SYSNOISE for measuring the vibration mode and character of response caused by sound radiation with adding the harmonic point force in the thin isotropic plate supported by the rectangular lattice reinforcement. We used the reinforcements, beams of open type section like the style of 'ㄷ' letter; the space of the beams were chosen to be 0.2m, 0.3m, 0.4m. We studied the behavior of sound pressure levels, analysis of vibration mode between support points, connection between frequency function and sound pressure levels, and connection between position function and sound pressure levels.

• Structural Engineering and Mechanics
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• 제55권6호
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• pp.1121-1137
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• 2015

High powered computers and engineering computer systems allow designers to routinely simulate complex physical phenomena. The presented work deals with the analysis of two finite element method optimization techniques (First Order Method-FOM and Subproblem Approximation Method-SAM) implemented in the individual Design Optimization module in the Ansys software to analyze the behavior of real problems. A design optimization is a difficult mathematical process, intended to find the minimum or maximum of an objective function, which is mostly based on iterative procedure. Using optimization techniques in engineering designs requires detailed knowledge of the analyzed problem but also an ability to select the appropriate optimization method. The methods embedded in advanced computer software are based on different optimization techniques and their efficiency is significantly influenced by the specific character of a problem. The efficiency, robustness and accuracy of the methods are studied through strictly convex two-dimensional optimization problem, which is represented by volume minimization of two bars' plane frame structure subjected to maximal vertical displacement limit. Advantages and disadvantages of the methods are described and some practical tips provided which could be beneficial in any efficient engineering design by using an optimization method.

• International journal of advanced smart convergence
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• 제8권1호
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• pp.166-175
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• 2019

Grit, a concept conceived in 2007 by Duckworth and others in the United States, is based on positive psychology that focuses on growth and development through individual strengths. Recently, "Grit", which means patience and enthusiasm for long-term goals, has emerged as a key factor of personality strength. In Korea, Joo-hwan Kim (2013) was the first to conceptualize and study the subject of Grit. However, there have been no overview studies that systematically summarize the overall trends and flow in the research of Grit so far. There have been 147 research papers on Grit published so far in Korea. The purpose of this study was to conduct trend analysis on the subject of Grit by analyzing forty-three (43) master's and doctoral dissertations, thus presenting the direction of future research on Grit through careful analysis. In the studies conducted, it was found that Grit is a very significant variable linked to self-efficacy. It is also a subjective belief that can help an individual achieve his/her educational goals, and go through failure resynchronization. In addition, Grit is very significant as a practical core indicator of how fusion talent is fostered for the fourth industrial revolution. Therefore, there is a need for more in-depth research from the viewpoints of workplace learning, experiential learning, or informal learning, as well as research into Grit characteristics.

• 정신분석
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• 제29권4호
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• pp.63-71
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• 2018

One of the most striking features of modern society in the 21st century, is increased levels of aggression. Aggression refers to aggressive or hostile behavior, and is manifested in suicide or an attack against others. Aggression in modern society is more accidental, reckless, and aimless than before. As more patients visit hospitals due to the serious problem of aggression control, we need to address the nature of this growing aggression. The authors analyzed sources and the nature of aggression, based on the movie 'American Psycho.' The main character of the movie, Patrick, is similar to many people today, with traits such as egotistical thinking, lack of empathy, demand for attention and admiration, and exploited and superficial relationships. Patrick's aggression is in reaction to narcissistic injury. Through this, one can think of pathological narcissism, behind growing aggression in modern society. There are a number of social and environmental factors, attributable to increasing narcissism in modern society. Among them, change in parenting practices, and parent-child relationships, is likely to have affected increase in narcissism in terms of personality development. In conclusion, when treating patients exhibiting aggression in psychotherapy, it is critical to fully consider the possibility of pathological narcissism and its use in analysis.