• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2008.05a
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• pp.129-129
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• 2008

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2004.10a
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• pp.44-44
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• 2004

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.10a
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• pp.627-627
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• 2007

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2006.11a
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• pp.117-117
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• 2006

• Korean Journal of Acupuncture
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• v.36 no.1
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• pp.92-92
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• 2019

• Journal of Acupuncture Research
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• v.19 no.6
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• pp.205-213
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• 2002

Objective : This study was to investigate on the Korean Bee-Venon acupuncture of Cauda equina syndrome which has been described as complex of low back pain, bilateral sciatica, saddle anesthesia and motor weakness in the lower extremity that progress to paraplegia with bladder and bowel incontinence. Methods : Clinical observation was done on Cauda equina syndrome in the Department of Acupuncture & Moxibustion, Kyungwon Inchon Oriental Medical Hospital from may 25 to June 24. The patients was treated with Korean Bee-Venon acupuncture at Samchosu(B22), Shinsu(B23), Taejangsu(B25), Pang-gwangsu(B28) and Yo-yang-gwan(Gv3) with oriental medicine treatment. We evaluated the bladder incontinence, duration of urination and area of anesthesia before and after treatment. Conclusions : 1. At the early time, gait disturbance was treated well, but discomfort bladder incontinence was remained. 2. The symptoms of Cauda equina syndrome especially bladder incontinence was recurred in short duration by Korean Bee-Venon acupuncture and oriental medicine treatment. 3. There was no significant changes in GOT/GPT before and after treatment.

• Applied Microscopy
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• v.27 no.2
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• pp.145-153
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• 1997

Histopathological and fine structural changes in mouse skin after injection of venoms extracted from the venom glands of the honeybee, Apis mellifera, were studied with light and electron microscopes. At this experiment the venoms were directly injected at the hairless abdominal skin of the mouse through the sting of the bee's venomous organ. Main changes appeared within one hour after injection at both epithelial and connective tissues as considerable hyperemia and angioedema, and slight edema and fibrosis. High magnified electron micrographs reveal not only increase of diameter but also deposition of electron dense grains (which seems to be an auto immunoglobulin) at the collagenous fibers characteristically. This kinds of histological and fine structural responses were diminished from 12 hour after injection, and the pathological symptoms disappeared within 3 days at most cases. So, the skin responses induced by honeybee venom seem to be not severe compare to other cases reported by other venomous arthropods.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.2
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• pp.212-220
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• 2012

In this study, we tried a study on a direction of the field of oriental medicine on accepting complementary alternative medicine by analyzing the related thesis, journals and papers on the complementary alternative medicine published in the field of oriental medicine. As the result of analyzing the present study of the field of oriental medicine on the complementary alternative medicine, there have been 22 studies on the complementary alternative medicine. Thesis, papers were mainly experimental papers about the bee venom therapy, energy therapy, fasting therapy, and colon therapy, and the journals were actively studied in order of clinical paper, experimental paper, and reference paper about the bee venom therapy, energy therapy, and reflexolgy. The acceptance of complementary alternative medicine by the field of oriental medicine through a scientific relation should be conducted more systemically by setting the main academy taking charge of the study on common characteristics of the complementary alternative medicines on the classification of NCCAM as well as the related academies taking charge of the study on the unique characteristic of each complementary alternative medicine. First, additional studies are needed to make the most of characteristics of each complementary alternative medicine through the main academy and the related academies, and for the next, additional studies are necessary to complement the research trend on each complementary alternative medicine through the main academy and related academies.

• Journal of Acupuncture Research
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• v.31 no.2
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• pp.173-182
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• 2014

Objectives : There are few reports on treatment of thoracic outlet syndrome in the field of traditional Korean medicine. The aim of this study is to report a case of a 29-year-old male patient diagnosed with thoracic outlet syndrome, whose symptoms were relieved after 3-week integrated Korean medical treatment. Methods : A patient diagnosed with thoracic outlet syndrome was admitted into the Korean medicine hospital. The patient had left shoulder pain and left arm numbness. The pain was worse if it had become cold. The patient was treated using Sa-am acupuncture(Daejangseunggyeok), sweet bee venom acupuncture, herbal medicine and other treatment including physical therapy from September 7th to 27th of 2012. Improvement of the patient's symptoms was evaluated by verbal numerical rating scale(VNRS), skin surface temperature difference between the left and right symmetric part of digital infrared thermographic image(DITI). Results : After 3-weeks of treatment, VNRS decreased and skin surface temperature difference between the left and right symmetric part of DITI showed moderate improvement. Conclusions : The results suggest that integrated Korean medical treatment may affect to reduce the symptoms of thoracic outlet syndrome. Further study is needed to evaluate the importance of this report.

• Journal of Acupuncture Research
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• v.28 no.3
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• pp.101-110
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• 2011

목적 : 이 연구는 봉독이 NF-${\kappa}$B의 활성억제를 통하여 전립선 암세포주인 DU-145 세포의 성장을 억제하 는지를 확인하고 그 기전을 살펴보고자 하였다. 방법 : 봉독을 처리한 후 DU-145의 성장억제를 관찰하기 위해 WST-1 assay를 시행하였고, 세포자멸사의 관찰에는 DAPI staining assay를 통한 세포형태관찰을 시행하였으며, 염증관련유전자 발현 관찰에는 western blot analysis를 시행하였고, 세포자멸사와 연관된 NF-${\kappa}$B의 활성 변화를 관찰하기 위해 EMSA와 luciferase assay를 시행하였으며, DU-145에서 봉독과 NF-${\kappa}$B의 상호작용을 관찰하기 위해 transient transfection assay를 시행하여 세포생존율과 NF-${\kappa}$B의 활성 변동을 측정하였다. 결과 : DU-145 세포에서 봉독을 처리한 후 세포성장이 억제되었으며, 염증관련유전자 발현 및 NF-${\kappa}$B의 활성의 유의한 감소를 나타내었다. DU-145 세포에서 NF-${\kappa}$B의 p50와 IKK들을 치환하여 작용기를 없애고 봉독을 처리하였을 경우에도 세포활성 및 NF-${\kappa}$B의 활성의 유의한 감소를 나타내었다. 결론 : 이상의 결과는 봉독이 NF-${\kappa}$B의 활성 억제를 통하여 인간 전립선암세포주인 DU-145의 세포자멸사를 유발함으로써 증식억제 효과가 있음을 입증한 것으로 전립선암의 예방과 치료에 대한 효과적인 치료제 개발에 도움이 될 것으로 기대된다. 다만 그 기전에서 봉독은 기존연구와 같은 NF-${\kappa}$B p50 및 IKK들의 작용기와 상호작용 이외에 다른 기전이 관여되는 것으로 심화 연구를 요한다.