• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.6 no.2
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• pp.61-70
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• 2011

Objectives : The purpose of this study was to investigate the effect of Bee-venom acupuncture on low back pain by traffic accidents. Methods : We included 34 patients with low back pain caused by TA for this study. The experimental group was treated by usual therapy plus Bee-venom acupuncture therapy, the control group was treated by usual therapy such as acupunture therapy and herbal medicine therapy. Oswestry Disability Index(ODI) and Visual Analog Scale(VAS) were evaluated at 4 week from baseline for the treatment effect in the both group. Results : After the subjects being treated by Bee-venom or general acupuncture therapy. It was detected that the scores of ODI and VAS in both groups decreased at the 4 week from baseline. There was significant difference between both groups in the VAS. However, there was no significant difference between both groups in the ODI. Conclusions : The results suggested that bee-venom acupuncture was effective on low back pain by traffic accidents.

• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.109-117
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• 2001

Objective : There has been no known report on the pain shock after administering Korean bee-venom therapy. Three accounts of pain shock were observed at the Sangji university affiliated Oriental medicine clinic from July 2001 through September 2001. This thesis will inform clinical progression and cautions on administering Korean bee-venom therapy. Methods: We were able to witness different patterns of pain shock during the treatment of degenerative knee joint, progressive oral paralysis, and A.L.S. In order to reduce heat toxicity of the bee venom, needling points were first massaged with the ice for 10 minutes before injecting $0.1{\sim}0.2cc$ of the bee venom. Points of injection were ST36, LI11, LI4 and others. Pain shock occurred after injecting on inner xi-an, outer xi-an and LI4. The phenomena associated with pain shock was recorded in chronological order and local changes were examined. Results: Through examining 3 patients with the pain shock, we managed to observe clinical progression, duration, and time linked changes on specific regions. We also managed to determine sensitive needling points for the pain shock. Conclution: Following results were obtained from 3 patients with the pain shock caused by Korean bee-venom therapy from July 2001 to September 2001. 1. Either positive or negative responses were shown after the pain shock. For case 1, extreme pain was accompanied with muscular convulsion and tremble, ocular hyperemia, delirium, stiffening of extremities, and hyper ventilation which all suggest positive responses. For case 2 and 3, extreme pain was accompanied with facial sweating, asthenia of extremities, pallor face, dizziness, weak voice, and sleepiness which are the signs of negative responses. 2. The time required to recover to stable state took nearly an hour (including sleeping time) and there was no side effect. 3. Precautions required to prevent the pain shock includes full concentration from the practitioner, accurate point location, precise amount of injection, physiological condition and psychological stability of the patient 4. Coping with the pain shock should be similar with a needle shock, and since extreme pain is accompanied, sufficient psychological rest must be provided. 5. Pain shock occurs because the patient cannot tolerate stimulation on the needling point. Thus, symptoms were similar to the needle shock in addition to excruciating pain. Further investigation and research must be done to have better understanding of an immune response and the pain shock associated with Korean bee-venom therapy.

• Journal of Acupuncture Research
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• v.20 no.3
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• pp.154-165
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• 2003

Objective : to research the trend of the study related to Bee venom and o establish the hereafter direction for the study on Bee Venom therapy. Methods : We reviewed the domestic papers published last ten years(1992-2001). Results: 1.We have searched 53 papers in 7 journals and the pattern of study was as follow: the experimental studies were 33, the clinical studies were 10 and the reviewed studies were 10. 2. The experimental studies were 2 papers of analysis of Bee Venom, 3 papers of safety assessment, 1 paper on production of antibody against Bee Venom and 26 paper of safety assessment. 3. Bee Venom used in studies was made in Korea, China and U.S.A.. There were differences of component and effect according to the place of production. 4. There were the experimental studies of LD50 in mouse, acute toxicity, local irritation test, antigenicity and pyrogen test of Bee Venom. Conclusions : We need more studies of unification of term about Bee Venom, difference according to the place of production, clinical safety and effects.

• Journal of Acupuncture Research
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• v.32 no.2
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• pp.209-216
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• 2015

Objectives : The objective of this study was to report two cases that patients with external epicondylitis were improved by based on 'eight vacuity' theory bloodletting therapy, acupuncture therapy and bee venom pharmacopuncture. Methods : In this study, patients were treated with bloodletting therapy, then acupuncture therapy and bee venom pharmacopuncture to Ashi point on eight vacuity of elbow in the patients without retention of needles. Subsequently, electroacupuncture and Dong-qi acupuncture treatment were implemented in order to strengthen the effect of acupuncture. In terms of evaluation methods, visual analog scale(VAS) score, range of motion(ROM), grip strength and physical examination were used to assess external epicondylitis-related symptoms. Results : VAS score decreased, ROM and grip strength were increased and physical examination was improved in all cases. Conclusions : It was suggested that the symptoms of intractable external epicondylitis could be improved by eight vacuity theory adopted bloodletting therapy, acupuncture therapy and bee venom pharmacopuncture.

• Korean Journal of Acupuncture
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• v.37 no.2
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• pp.76-87
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• 2020

Objectives : Bee venom has been widely practiced in many countries around the world. The number of clinical trials and biochemical researches on bee venom has been constantly increasing. The objective of this study is to analyze the trend of research on bee venom using bibliometric approach, a quantitative analytical method. Methods : We searched articles about bee venom which were published from 2000 to 2019 from Web of Science Database. Original and review articles published in English were included and data were extracted in terms of publication year, country, journal, keywords, organizations, and authors. Trends in bee venom research were visualized using VOSviewer program. Results : 1,547 English articles about bee venom were identified and analyzed. South Korea is a main hub in the field of bee venom research. Research organizations in South Korea showed high link strength with domestic organizations as well as with international organizations. A keyword analysis showed the following three major types of studies: studies on components of bee venom, studies on allergy and immune response, and clinical research of bee venom therapy. Conclusions : This study provides a macroscopic overview of the research on bee venom. This bibliometric analysis has identified influential authors and organizations in the field on bee venom research and provides a useful guideline to researchers who are in search of contributory research topics.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.3
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• pp.201-210
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• 2008

Objectives : This report was performed to evaluate the treatment of acupuncture therapy, Bee venom acupuncture therapy and herbal medication in Baastrup's disease. Methods : We treated 1 case of Baastrup's disease with acupuncture therapy, Bee venom acupuncture therapy one times a week and took herbal medicine after a meal two times daily. The patients' symptoms were assessed 3 month, 6 month, 9 month by Visual analogue scale(VAS), Oswestry disability index(ODI). Results : Visual Analog Scale(VAS), Oswestry Disability Index(ODI) was significantly improved after treatment for 9 months. Conclusions : This study suggested that acupuncture therapy, Bee venom acupuncture therapy and herbal medicine can be effective for decreasing pain and improving functional recovery. We think that it need the further study and clinical trial for Baastrup's disease.

• Journal of Pharmacopuncture
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• v.5 no.2
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• pp.109-115
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• 2002

Objective : This study was performed to evaluate the treatment of Acupuncture therapy including Herbal Acupuncture theraphy and Korean Bee Venom Theraphy in Klippel-Trenaunay-Weber Syndrome. Methods : We treated 1 case of Klippel-Trenaunay-Weber Syndrome patient with mainly Korean Bee Venom Theraphy, and herbal Acupuncture, acupuncture theraphy from 27th August, 2001 to February, 2003. Results : After 3 weeks of Korean Bee Venom Theraphy, and herbal Acupuncture, acupuncture theraphy, a remarkable improvement was made for Klippel-Trenaunay-Weber Syndrome. Conclusions : Korean Bee Venom Theraphy and other acupuncture therapies were effective in reducing the symptoms. We think that it need the further study and clinical trial for Klippel-Trenaunay-Weber Syndrome.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.3
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• pp.703-707
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• 2008

To examine the efficacy of electrical acupuncture combined bee venom in controlling low back with leg pain induced Herniated Intervertebral Disc (HIVD). 13 patients (men 8, women 5; age $41.30\;{\pm}\;17.27$) diagnosed as HIVD by CT or MRI had low back and leg pain as a chief complaint and diseases such as spinal tumor, infection and fracture were excluded. They were treated by electrical acupuncture (8 Hz) combined bee venom therapy three times a week in Wonkwang University Hospital, and pain intensity with VAS and functioning with Roland-Morris Disability Qestionnaire(RDQ) were measured at the baseline(B), and 4 weeks after treatment. The data were analyzed with Wilcoxon signed ranks test(SPSS12.0) and the level set for statistical significance was P<0.05. The pain was significantly reduced by two combined treatments (=0.002;$B7.69{\pm}2.06$,4Wks$4.70{\pm}2.72$). The function was also significantly improved by both treatments(=0.001;$B12.15{\pm}6.85$,4Wks$6.85{\pm}5.15$). The results suggest that a combination of acupuncture and bee venom therapy may be beneficial for low back pain from HIVD. In future, randomized clinical trials including follow-up are needed to examine the effects of these therapies.

• Journal of Pharmacopuncture
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• v.8 no.2
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• pp.17-22
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• 2005

Objective : This study was performed to evaluate the treatment of acupuncture therapy including. Bee Venom and Hominis Placenta herbal acupuncture on the patient with Transverse myelitis. Methods : We treated the patient with Transverse myelitis by Bee Venom herbal acupuncture at beginning, since then we treated him adding to Hominis Placenta herbal acupuncture. Conclusions: The patient was effectively reduced symptoms with Bee Venom herbal acupuncture, since then he get more effective improvement of symptoms by adding Hominis Placenta herbal acupuncture. Therefore we are able to expect Bee Venom and Hominis Placenta herbal acupuncture will be more effective than simply acupuncture on the patient with Transverse myelitis.

• Journal of Acupuncture Research
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• v.27 no.3
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• pp.159-166
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• 2010

Objectives : This study was to observe the effect of Hapgok needling and Bee Venom Acupuncture on a patient with neuralgia caused by Carpal Tunnel Syndrome. Methods : The patient were treated by Hapgok needling and Bee Venom Acupuncture at acupuncture points following diagnosed as Carpal Tunnel Syndrome. Improvement of the symptoms was evaluated by VAS. Results : Carpal Tunnel Syndrome related symptoms of the patient were remarkably improved by Hapgok needling and Bee Venom Acupuncture therapy. Conclusions : These results suggested that Hapgok needling and Bee Venom Acupuncture should be one of the useful treatment methods for relieving the symptoms of Carpal Tunnel Syndrome.