• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2003년도 하계 학술대회 논문집
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• pp.309-316
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• 2003

참깨탈곡의 생력기계화를 위해 일관작업이 가능한 참깨탈곡기를 개발하여 시험한 결과를 요약하면 다음과 같다. 가. 타격식 탈곡요인시험 결과 타격수 14, 17cpm에서 탈곡률은 98.5, 98.7%, 미탈곡률은 1.1, 1.0%, 배출구 손실률은 0.4. 0.3%로 가장 양호하게 나타났다. 나. 타격식 탈곡물의 정선요인시험결과 경사 12$^{\circ}$, 요동수 220cpm일 때 탈곡률과 미정선 손실률이 각각 97.2%와 0.6%로 가장 양호하게 나타났다. 다. 타격식 탈곡부와 정선부를 조합한 시작기의 성능시험결과 공급량 15단/min, 타격수 14cpm, 정선체 요동수 220cpm에서 탈곡률은 98.7%, 탈곡부 손실률은 1.3%, 정선율은 97.0%, 미정선 손실률 0.7%로 나타났다. 라. 시작기는 10a당 작업성능이 0.5시간으로 인력 4.8시간에 비해 9.6배 능률적이고 소요경비가 17,471원으로 인력 32,290원에 비해 45.9% 절감되는 것으로 나타났다

• Journal of Chest Surgery
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• 제33권5호
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• pp.398-406
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• 2000

Background: Cardiac atrium is an endocrine gland secreting a family of natriuretic peptides. The secretion of atrial natriuretic peptide(ANP) had been shown to be controlled by variable factors. The change in atrial dynamics have been considered as one of the most prominent stimuli for the stimulation of ANP secretion. Hypoxic stress has been shown to increase cardiac ANP secretion. However, the mechanism by which hypoxia increases ANP secretion cardiac ANP secretions. However, the mechanism by which hypoxia increases ANP secretion has not to be defined. Therefore, the purpose of the present study was tow-fold: to develop a protocol to defined the effect of hypoxia on ANP secretion in perfused beating rabbit atria and to clarify the mechanism responsible for the accentuation by hypoxia of ANP secretion. Material and Method: Experiments have been done in perfused beating rabbit atria. ANP was measured by radioimmunoassay. Result: Hypoxic stimulus with nitrogen decreased atrial stroke volume. The decrease in atrial stroke volume recovered basal level during the period of recovery with oxygen. ANP secretion and the concentration of perfusate ANP in terms of extracellular fluid(ECF) translocation which reflects the rate of myocytic release of ANP were increased by hypoxia and returned to basal levels during the recovery. Changes in ECF translocation paralleled by hypoxia and returned to basal levels during the recovery. Changes in ECF translocation paralleled to that of atrial stroke volume. At the start of recovery in atrial storke volume, ECF tranalocation incrased for several minutes. The above responses were stable and reproducible. Glibenclamide treatment prevented the recovery in atrial stroke volume. Increments by hypoxia of ANP secretion and ANP concentration were suppressed by glibenclamide. Conclusion: These results indicate that hypoxia incrased atrial myocytic ANP release and that the mechanism responsible for the accentuation is partially related to the change in K+ATP channel activity.

• 한국윤활학회:학술대회논문집
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• 한국윤활학회 1998년도 제27회 춘계학술대회
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• pp.212-217
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• 1998

Reynolds equation, which describes behavior of fluid film in journal bearing, basically satisfies mass conservation. But, boundary conditions usually used with this equation, e.g. half Sommerfeld or Reynolds boundary conditions, cannot fulfill this natural law of conservation. In the case of connecting rod bearing, where applied load is dynamic and its magnitude is relatively large, such unrealistic boundary conditions have serious influence on calculation results, especially on lubricant flow rate or power dissipation which are important parameters in thermal analysis. Another important factor in the analysis of connecting rod bearing is elastic deformation of bearing support structure which is relatively flexible. In this paper, EHL analysis of connecting rod beating is performed using mass-conserving boundary condition. Elastic deformation of bearing support structure and application of mass-conserving boundary condition have significant effects on the performances of connecting rod bearing.

• Archives of Pharmacal Research
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• 제17권3호
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• pp.150-153
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• 1994

Ethanolic extract of Daucus carota (DC) at the dose of 10-100 mg/kg caused a dose-dependent fall in systolic and diastolic arterial blood pressure in nomotensive anesthetized rats. These effects were not blocked by atropine (1 mg/kg) and pretratment with DC did not alter the pressor response to norepinephrine indicating that cardiovascular effects of DC are independent of cholinergic or adrenergic recptors involvement. In spontaneously beating guinea-pig paired atria, DC induced a concentration-dependent (03-5 mg/ml) decrease in force and rate of atrial contractions. In rabbit thoracic aorta, DC caused inhibition of $K^+$-induced contractions at similar concentrations. These results suggest that the extract may exhibit $Ca^{2+}$ channel blocking-like direct relaxant action on cardiac and smooth muscle preperations and this action may be responsible for its hypotensive effect observed in the in vivo studies.

• Journal of Chest Surgery
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• 제29권11호
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• pp.1263-1266
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• 1996

단국대학교병원 흉부외과에서는 좌전하행지 기시부부터 95% 이상 협착을 보이는 단일혈관질환 1례에서 체외순환없이 제한적 전흉부 개흉으로 좌측내유동맥을 박리하여 박동심장하에서 관상동맥우회술을 성공적으로 시행하였기에 보고하는 바이다.

• Journal of Chest Surgery
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• 제29권4호
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• pp.365-372
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• 1996

St. Thomas' 심정지액 I과 II가 백서 배양심근세포에 미치는 영향을 알아보기 위하여 심장 박동수, MTT 정량, LDH 정량 및 형태학적 관찰을 시행하였다. 백서의 심근 세포를72시간 배양한 후St. Thomas' 심정지액 I과 H에 30분및 120분간 처리한후24 시간 동안 배양하여 다음과 같은 결과를 얻었다. 1. 심근 세포 박동수는 대조군이 분당 154회, St. Thomas' 심정지액 I 에 120분 처리한 실험군에서는 147회, II 120분처리군에서는 145회로대조군에 비하여 유의한 차이를 보이지 않았다. 2. MTT 정량 결과St. Thomas' 심정지액 1120분 처리군에서는대조군의 102%로나타났으며. R B2O 분처리군에서는 93%로 대조군에 비하여 유의한 차이를 보이지 않았다. 3. LDH정량 결과 St. Thomas' 심정지액 1120분처리군에서는대조군의 123%로나타났으며, R 120 분처리군에서는 109%로 약간의 증가를 보였다. 4. 광학현미경적 관찰결과세포수및 세포 형태에 있어서 대조군과 실험군간에 차이를 보이지 않았다. 5.전자현미경적 관찰 결과St. Thomas'심정지액 I 처리군에서는소수의 미토콘드리아파괴가관찰되 었으며, II 처리군에서는대조군과유사한소견을보였다. 이상의 실 瘟嘯倖?종합하여 볼때, St. Thomas'심정지액 I과 II는백서 배양심근세포에 세포독성 을 나타내지 않았으나,전자현미경적 관찰결과심정지액 II가심정지액 I에 비하여 심근보호효과가 더 양호한 것으로 생각된다.

• 한국임상약학회지
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• 제21권1호
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• pp.6-13
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• 2011

Bolus intravenous injection of adenosine resulted the temporal decrease of systemic blood pressure and heart rate in the anesthetized rats. Adenosine also resulted the persistent decrease of contractility and heart rate in the isolated spontaneously beating rat right atria. Both of the above inhibition effets of adenosine were increased by the pretreatment of NBI (nitrobenzylthioinosine), whitch is an adenosine transport inhibitor, but decreased by the pretreatment of 8- phenyltheophy1line, which is an adenosine antagonist. In isolated thoracic aorta ring segment of normotensive rats, intact rings were relaxed by adenosine ($42.3{\pm}8.7%$) and ATP ($85.9{\pm}15.8%$) in the concentration of $10^{-4}M$, but rubbed rings were relaxed by adenosine ($35.2{\pm}1.9%$) and ATP ($11.3{\pm}9.0%$) in $10^{-4}M$. After pretreatment of L-NAME (N-Nitro-Larginine methyl ester), which is an NO inhibitor, adenosine-induced relaxation was not affected, but ATP-induced relax ation was significantly inhibited (P<0.01). Meanwhile, adenosine resulted almost same as vasorelaxation in isolated thoracic aorta of SHR comparing to those of normotensive rats. But, vasodilation responses of ATP in intact rings of SHR are significantly inhibited comparing to those of normotensive rats. Adenosine-induced relaxation is attenuated after 8-phenyltheophylline pretreatment, but increased after NBI pretreatment. However, ATP-induced relaxations are not affected by 8-phenyltheophylline or NBI pretreatment. These results suggested that the hypotensive effects of adenosine was due to the decrease of contractile force and heart rate through the A1 receptor and vasodilation are mediated by A2 receptor of the vascular smooth muscle. And, the heart protective and vasodilation effects of adenosine might suggest that it would be useful in the acute treatment of coronary artery disease.

• 한국정보통신학회논문지
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• 제7권5호
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• pp.1076-1081
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• 2003

본 논문에서는 반도체레이저를 이용한 밀리미터파 대역의 신호를 생성하는 방법에 대해 제안하였다. 광대역에서의 밀리미터파 신호를 얻기 위해서는 윈하는 공진 주파수대역의 신호를 얻기 위해는 서브 하모닉의 좁은 신호 성분의 하모닉 신호인 다중의 신호를 서로 beating하여 원하는 주파수 대역의 신호를 얻을 수 있다. 따라서 본 논문에서는 반도체레이저를 사용한 광주입 방법을 통하여 실제적으로 원하는 주파수 대역의 신호를 얻기 위해 실험적으로 고찰하였으며, 신호 성분의 성능을 구하기 위해 phase noise 성분을 측정하였다.

• 한국공작기계학회논문집
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• 제14권6호
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• pp.31-36
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• 2005

Use of the high frequency motor spindles are increasing for the high speed machine tools recently. The important problem in the high speed spindles is to reduce and minimize the thermal effect by the motor and ball hearings. Thermal characteristics according to the bearing preload and spindle cooling are studied for the spindle with the oil mist lubrication and high frequency motor. Temperature distribution and thermal displacement according to the spindle speed, preload and flow rate are measured. Temperature distribution and thermal displacement of the high speed spindle system can be estimated reasonably by using the three dimensional model through the finite element method. The results of analysis are compared with the measured data. This study supports thermal optimization and find out more effective cooling condition. This paper show that the suitable preload and spindle cooling are very effective to minimize the thermal effect by the motor and ball bearings.

• 사상체질의학회지
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• 제13권1호
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• pp.70-78
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• 2001

ADR유발성 심근독성에 대한 심근세포의 손상기전을 규명하기 위해 ADR의 독성을 MTT정량, NR정량, LDH활성도 및 심박동을 측정하였다. 배양된 심근세포에서 청심연자탕 전탕액의 심근세포 보호효과는 LDH활성도 측정과 심박동 측정을 통해 관찰할 수 있었다. 이 실험을 통해 다음과 같은 결과를 얻을 수 있었다. 1. ADR은 배양심근세포에서 세포의 생존능력을 떨어뜨렸고, LDH의 활성도를 높였으며, 심박동수를 감소시켰다. 2. 청심연자탕 전탕액은 배양심근세포에서 ADR에 의해 증가된 LDH 활성도를 유의하게 감소시켰다. 3. 청심연자탕 전탕액은 배양심근세포에서 ADR에 의해 감소된 심박동을 유의하게 증가시켰다. 이상의 결과를 통해 ADR은 신생 마우스에서 적출해낸 배양 심근세포에서 독성효과를 나타냈음을 알 수 있었으며, 청심연자탕 전탕액은 ADR에 의해 유발된 심근세포독성에 매우 효과적으로 방어효과를 나타냄을 알 수 있었다.