• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3309-3312
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• 2010

D-[$^{18}F$]FMAU and L-[$^{18}F$]FMAU are F-18 labeled nucleoside analogue which have been efficiently synthesized in order to be a PET imaging probe. D-[$^{18}F$]FMAU and L-[$^{18}F$]FMAU were compared as PET imaging agents using HSV1-TK gene expressing tumor-bearing mice. Their cellular uptake profiles were also compared using MCA and MCA-TK cell lines. D-[$^{18}F$]FMAU demonstrated higher cellular uptake and higher accumulation in MCA-TK tumor regions than L-[$^{18}F$]FMAU. On the other hand, L-[$^{18}F$]FMAU showed higher MCA-TK/MCA ratio of %ID/g than that of D-[$^{18}F$]FMAU. L-[$^{18}F$]FMAU can be utilized as a good candidate for HSV1-TK PET imaging. It can be used for antiviral drug evaluation.

• Korean Journal of Acupuncture
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• 제35권1호
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• pp.27-35
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• 2018

Objectives : The purpose of this study was to investigate the analgesic effect of electroacupuncture(EA) and radio-frequency warm needling(RFWN) stimulation in acupoint combination on ankle sprained pain in rats. Methods : The lateral ligaments of the Sprague-Dawley rats ankle were injured surgically resulting in sprain, of which was divided into EA, RFWN treatment groups and control group without treatment. The level of pain was measured through foot weight bearing force ratio followed by calculating pain relief. To stimulate proximal or distal area in ankle sprain, combination of proximal acupoints(GB34-GB39) and distal acupoints(GB39-GB42) from sprain area were applied, respectively, to either EA or RFWN stimulation. In addition, naltrexone or phentolamine was injected intraperitoneally before the stimulation to observe the pathway of analgesic effects. Results : In the proximal combination of GB34-GB39, EA and RFWN significantly increased pain relief compared to the control group (p<0.05). However, in distal combination with GB39-GB42, both EA and RFWN stimulation did not relieve pain due to ankle sprains. In the combination of GB34-GB39, the analgesia of EA was inhibited by blockade of the ${\alpha}$-adrenoceptor receptor. The analgesia of RFWN was inhibited by blockade of the ${\alpha}$-adrenoceptor receptor as well as ${\mu}$-opioid receptor. Conclusions : We observed that the proximal combination was effective in relieving pain when the treatment by acupoint combination was applied to the ankle sprain pain. Also, it was confirmed that this analgesia was also related to the pathways of ${\mu}$-opioid receptors and/or ${\alpha}$-adrenoceptors.

• 한국전문물리치료학회지
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• 제23권3호
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• pp.40-47
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• 2016

Background: Assessments of Sit-to-Stand (STS) and gait functions are essential procedures in evaluating level of independence for the patients after stroke. In a previous study, we developed the software to analyze center of pressure (COP) in standing position on Wii Balance Board (WBB). Objects: This purpose of this study is to measure test-retest reliability of ground reaction forces, COP and time using WBB on STS and gait in healthy adults. Methods: Fifteen healthy participants performed three trials of STS and gait on WBB. The time (s), vertical peak (%) and COP path-length (cm) were measured on both tasks. Additionally, counter (%), different peak (%), symmetry ratio, COP x-range and COP y-range were analyzed on STS, 1st peak (%), 2nd peak (%) of weight were analyzed on gait. Intra-class correlation coefficient (ICC), standard error measurement (SEM) and smallest real difference (SRD) were analyzed for test-retest reliability. Results: ICC of all variables except COP path-length appeared to .676~.946 on STS, and to .723~.901 on gait. SEM and SRD of all variables excepting COP path-length appeared .227~8.886, .033~24.575 on STS. SEM and SRD excepting COP path-length appeared about .019~3.933, .054~11.879 on gait. Conclusion: WBB is not only cheaper than force plate, but also easier to use clinically. WBB is considered as an adequate equipment for measuring changes of weight bearing during balance, STS and gait test which are normally used for functional assessment in patients with neurological problems and elderly. The further study is needed concurrent validity on neurological patients, elderly patients using force plate and WBB.

• Bulletin of the Korean Chemical Society
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• 제34권2호
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• pp.399-405
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• 2013

Two series of new green phosphorescent polymers bearing a bis(2-phenyl-pyridine)iridium(III)(dibenzoylmethane) [$(ppy)_2Irdbm$] complex were designed and synthesized. Poly-carbazole (PCbz) derivative or polyfluorene with pendant carbazole groups (PFCbz) were employed as host polymers for the iridium complex. The iridium complex monomer was copolymerized with the host monomers using varying monomer ratios via a Yamamoto coupling reaction. Efficient energy transfer from host to dopant unit was observed by increasing the ratio of the iridium guest in the copolymers. Electroluminescent devices with the configuration ITO/PEDOT:PSS/polymer/BmPyPB/LiF/Al were fabricated and characterized. The phosphorescent polymers composed of the iridium complex guest and polyfluorene with carbazole pendants as a host performed better than the polymers composed of the same guest and the main chain polycarbazole host. A maximum external quantum efficiency of 0.73%, a luminous efficiency of 1.21 cd/A, and a maximum luminance of 372 $cd/m^2$ were obtained from a device fabricated using one of the synthesized copolymers.

• Corrosion Science and Technology
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• 제9권1호
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• pp.20-28
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• 2010

According to the bipolar model, ion selectivity of some species in the passive film is important factor to control the passivation. An increase of cation selectivity of outer layer of the passive film can stabilize the film and improves the corrosion resistance. Therefore, the formation and roles of ionic species in the passive film should be elucidated. In this work, two types of solution (hydrochloric or sulfuric acid) were used to test high N and Mo-bearing stainless steels. The objective of this work was to investigate the formation of oxyanions in the passive film and the roles of oxyanions in passivation of stainless steel. Nitrogen exists as atomic nitrogen, nitric oxide, nitro-oxyanions (${NO_x}^-$), and N-H species, not nitride in the passive film. Because of its high mobility, the enriched atomic nitrogen can act as a reservoir. The formation of N-H species buffers the film pH and facilitates the formation of oxyanions in the film. ${NO_x}^-$ species improve the cation selectivity of the film, increasing the oxide content and film density. ${NO_x}^-$ acts similar to a strong inhibitor both in the passive film and at active sites. This facilitates the formation of chromium oxide. Also, ${NO_x}^-$ can make more molybdate and nitric oxide by reacting with Mo. The role of Mo addition on the passivation characteristics of stainless steel may differ with the test environment. Mo exists as metallic molybdenum, molybdenum oxide, and molybdate and the latter facilitates the oxide formation. When nitrogen and molybdenum coexist in stainless steel, corrosion resistance in chloride solutions is drastically increased. This synergistic effect of N and Mo in a chloride solution is mainly due to the formation of nitro-oxyanions and molybdate ion. Oxyanions can be formed by a 'solid state reaction' in the passive film, resulting in the formation of more molybdate and nitric oxide. These oxyanions improve the cation selectivity of the outer layer and form more oxide and increase the amount of chromium oxide and the ratio of $Cr_2O_3/Cr(OH)_3$ and make the film stable and dense.

• 구강회복응용과학지
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• 제19권3호
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• pp.153-168
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• 2003

It is very important to arrange the artificial teeth correctly in bucco-lingual (labio- lingual) relation in reconstrcting dentition. Although many anatomic landmarks and techniques have been reported over the years, they are based on westerns. So this study was performd to examine the horizontal relations of mandibular teeth in Korean dentulous adults. 200 volunteers(mean age 22.9) who had natural dentition were selected. The impressions were taken with irreversible hydrocolloid impression material and mandibular study models were fabricated using class I dental stone. Then they were measured with 3-dimensional measuring device specially designed for this study. The results were as follows ; It is better to consider the lingual cusps of the lower posterior teeth as a guide than the linguoaxial surfaces of the lower posterior teeth, arranging the lower posterior teeth buccally to the line which starts from the mesial aspect of the lower canine and continue backward to the lingual aspect of the retromolar pad. It is better to arrange the fossae of the lower posterior teeth buccally to the line which starts from the cusp tip of the lower canine and continue backward to the top of the retromolar pad. The positions of the lower posterior teeth in the denture-bearing area ; considering the fossa as a guide, the 2nd premolar was positioned in center. considering the buccal cusp as a guide, the 1st molar and the 2nd molar were positioned in center. the distance ratio(d/a) was incresed constantly from the lower canine to the 2nd molar d ; the distance between the buccal vestibule(the lowest point) and the buccal cusp tips of the lower posterior teeth. a ; the distance between the buccal vestibule(the lowest point) and the lingual vestibule(the lowest point). The lower canine was positioned lingually($0.11{\pm}0.13$) than the labial vestibule, and the central incisor and the lateral incisor were positioned almost in the imaginary perpendicular plane of the labial vestibule(the lowest point).

• 암석학회지
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• 제6권1호
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• pp.52-64
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• 1997

캐나다 노바스코시아주 남서쪽에 분포하는 이질암류는 셀르론화강암의 관입에 의해 넓은 지역이 접촉변성을 받았다. 이곳에 분포하는 접촉변성대는 15km 두께에 이른다. 잘 발달된 가상구조(pseudomorphic textures)에 의하면 사장석-백운모-흑운모가 십자석과 홍주석으로 치환되어있다. 이러한 치환반응이 가능하려면 반응물에는 존재하나 생성물에는 존재하지 않는 K, Na, Ca 원소들의 반응게에서 빠져 나와야만 가능하다. 이는 연구지역에서 원소들이 넓은 접촉 오레올을 이동한 광역의 변성교대작용이 발생하였음을 암시해 주고 있다. 홍주석을 함유하는 전형적인 시료의 모달 분석결과 반응물과 생성물의 체적비율이 1:1 관계를 보이고 있다. 동일체적일 경우 생성물(홍주석)에 함유된 Al의 양이 반응물들(사장석-백운모-흑운모)에 함유된양 보다 3배가 많음을 감안할때 이러한 화학반응을 가능하게 하려면 Al 역시 접촉변성 지역에서 원거리를 이동하였다는것을 알 수 있다.

• 대한족부족관절학회지
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• 제16권3호
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• pp.169-174
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• 2012

Purpose: There are various methods proposed for the evaluation of the hindfoot alignment. However, due to structural calcaneus variances between patients, it is hard to assess this alignment definitively. Thus, this study proposes a new method for evaluating of the hindfoot alignment and its comparisons to the existing current methods. Materials and Methods: This study includes simple weight bearing hindfoot coronal view radiographs of 120 patients, taken between the time period of March 2008 to November 2009. Among the 120 patients, there was a 1:1 ratio of male to female with an average age of 40. The newly proposed method for evaluating this alignment is to draw a moment arm from the point where the sustentaculum tali meets the medial calcaneus border to the most prominent aspect of the lateral process of the calcaneal tuberosity. The angle produced via the intersection of this moment arm to the mid-longitudinal axis of the tibia is found and used to evaluate the hindfoot alignment. The inter and intra-observer reliability was evaluated using the coefficient of intraclass correlation. This study also investigates the comparisons between the newly proposed method to the traditionally used Saltzman et al hindfoot alignment evaluating technique. Results: The newly proposed method has higher inter and intra-observer reliability than the existing traditional Saltzman et al technique. Conclusion: This new method is recommended over the traditionally used Saltzman et al technique as it has a stronger confidence level and is appropriate for assessing hindfoot alignment in simple radiographs.

• 한국건설순환자원학회논문집
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• 제8권2호
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• pp.153-160
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• 2020

본 연구에서는 이산화탄소 포집광물을 심층혼합처리용 Soil-cement로 활용하기 위하여 최적 Soil-cement의 배합비를 도출하였으며, 이산화탄소 포집광물이 혼합된 Soil-cement의 품질특성을 평가하였다. 이산화탄소 포집광물은 슬러리 형태로 발생되며, 함수량 평가결과, 약 50%로 나타났다. 따라서, Soil-cement의 배합시 단위수량에서 이산화탄소 포집광물의 함수량을 제외하였다. 이산화탄소 포집광물 활용 Soil-cement를 현장토에 대하여 현장배합을 실시한 결과 재령 28일 기준 3.0MPa 이상을 나타냄으로써 설계 허용지지력 기준을 만족하는 것으로 나타났다. 이산화탄소 포집광물의 유해성 검증을 실시한 결과 구리(Cu)의 경우 0.055mg/L 검출되었지만 허용기준치에 만족하였으며, 이 외의 유해 물질은 용출되지 않은 것으로 분석되었다.

• 한국작물학회지
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• 제31권2호
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• pp.156-161
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• 1986

옥수수 흑조위축병이 심한 남부지방에서 6개 국내육성품종과 6개 미국도입 품종의 흑조위축병 발생상황과 Silage 생산성에 관한 연구결과는 다음과 같다. 1. 흑조위축병에 의하여 간장의 위축이 심한 품종일수록 간장의 변이계수가 컸다. 2. 간장의 도수분포는 흑조위축병 이병율과 분포의 유형에 따라 3품종군으로 나눌 수 있었다. 3. 수확기의 흑조위축병 이병율과 간장 자수주비율, Silage 수량, 자수수량과는 부의 상관이 있었으나 Silage 중 자수비율과 간엽수량과는 상관이 없었다. 4. Silage 수량은 P. XCF38이 가장 높았고 수원 89호와 NC6131 이 가장 낮았으며 타 품종은 육성모지와 관계없이 비슷하였다. 5. 흑조위축병 이병율은 P. XCF38, 수원 89호, 진주옥이 가장 낮았으며 수원 19호, 광옥, 횡성옥, P. 3424는 이병률이 비교적 높았고 NC 6131은 생육초기부터 이병률이 가장 높았다. 6. 진주옥과 수원 89호는 흑조위축병에는 저항성이나 출사후 잎의 조기노화로 수량이 낮았다.