• Title/Summary/Keyword: Bayes method

Search Result 365, Processing Time 0.027 seconds

A variational Bayes method for pharmacokinetic model (약물동태학 모형에 대한 변분 베이즈 방법)

  • Parka, Sun;Jo, Seongil;Lee, Woojoo
    • The Korean Journal of Applied Statistics
    • /
    • v.34 no.1
    • /
    • pp.9-23
    • /
    • 2021
  • In the following paper we introduce a variational Bayes method that approximates posterior distributions with mean-field method. In particular, we introduce automatic differentiation variation inference (ADVI), which approximates joint posterior distributions using the product of Gaussian distributions after transforming parameters into real coordinate space, and then apply it to pharmacokinetic models that are models for the study of the time course of drug absorption, distribution, metabolism and excretion. We analyze real data sets using ADVI and compare the results with those based on Markov chain Monte Carlo. We implement the algorithms using Stan.

Accurate Intrusion Detection using n-Gram Augmented Naive Bayes (N-Gram 증강 나이브 베이스를 이용한 정확한 침입 탐지)

  • Kang, Dae-Ki
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2008.10a
    • /
    • pp.285-288
    • /
    • 2008
  • In many intrusion detection applications, n-gram approach has been widely applied. However, n-gram approach has shown a few problems including double counting of features. To address those problems, we applied n-gram augmented Naive Bayes directly to classify intrusive sequences and compared performance with those of Naive Bayes and Support Vector Machines (SVM) with n-gram features by the experiments on host-based intrusion detection benchmark data sets. Experimental results on the University of New Mexico (UNM) benchmark data sets show that the n-gram augmented method, which solves the problem of independence violation that happens when n-gram features are directly applied to Naive Bayes (i.e. Naive Bayes with n-gram features), yields intrusion detectors with higher accuracy than those from Naive Bayes with n-gram features and shows comparable accuracy to those from SVM with n-gram features.

  • PDF

Safety Improvement Analysis of Roundabouts in Jeollabuk-do Province using Accident Prediction Model (사고예측모형을 활용한 회전교차로 안전성 향상에 관한 연구 - 전라북도를 중심으로 -)

  • Kim, Chil Hyun;Kwon, Yong Seok;Kang, Kuy Dong
    • International Journal of Highway Engineering
    • /
    • v.18 no.4
    • /
    • pp.93-102
    • /
    • 2016
  • PURPOSES : There are many recently constructed roundabouts in Jeollabuk-do province. This study analyzed how roundabouts reduce the risk of accidents and improve safety in the province. METHODS : This study analyzed safety improvement at roundabouts by using an accident prediction model that uses an Empirical Bayes method based on negative binomial distribution. RESULTS : The results of our analysis model showed that the total number of accidents decreased from 130 to 51. Roundabouts also decreased casualties; the number of casualties decreased from 7 to 0 and the seriously wounded from 87 to 16. The effectiveness of accident reduction as analyzed by the accident prediction model with the Empirical Bayes method was 60%. CONCLUSIONS : The construction of roundabouts can bring about a reduction in the number of accidents and casualties, and make intersections safer.

The Method to Measure Saliency Values for Salient Region Detection from an Image

  • Park, Seong-Ho;Yu, Young-Jung
    • Journal of information and communication convergence engineering
    • /
    • v.9 no.1
    • /
    • pp.55-58
    • /
    • 2011
  • In this paper we introduce an improved method to measure saliency values of pixels from an image. The proposed saliency measure is formulated using local features of color and a statistical framework. In the preprocessing step, rough salient pixels are determined as the local contrast of an image region with respect to its neighborhood at various scales. Then, the saliency value of each pixel is calculated by Bayes' rule using rough salient pixels. The experiments show that our approach outperforms the current Bayes' rule based method.

Effect Analysis on Red Light Camera for Signalized Intersection Safety -Focused on Side Right-Angle Collision Accidents- (신호교차로 안전성향상을 위한 단속카메라의 효과분석 연구 -측면직각 충돌사고를 중심으로-)

  • Oh, Ju Taek;Kim, Yong Seok;Lee, Yong Chul
    • International Journal of Highway Engineering
    • /
    • v.17 no.1
    • /
    • pp.119-127
    • /
    • 2015
  • PURPOSES : Before-and-after studies of red light cameras were conducted with the aim of reducing the number of side right-angle collisions. Three different methods were used for the before-and-after studies, and the analysis results were compared. METHODS : This research used the naive before-and-after method, the comparison-group method, and the empirical Bayes method to study the effects of red light cameras on side-angle collisions. The results of the three before-and-after methods were compared and interpreted in terms of safety indications at signalized intersections. RESULTS : The research results showed that side right-angle collisions can be reduced by installing red light cameras at signalized intersections. All three methods guarantee safety improvements of 25~30% on average. With regard to the results of each method, the naive before-and-after method, the comparison-group method, and the empirical Bayes method showed safety improvements of 25.6%, 27.8%, and 29.7%, respectively. CONCLUSIONS : It was concluded that red light cameras are an effective countermeasure to improve intersection safety. In particular, by installing red light cameras, side right-angle collisions can be reduced by up to approximately 25~30%.

Hierarchical Bayes Estimators of Exchangeable Poisson Mean using Laplace Approximation

  • Chung, Youn-Shik
    • Communications for Statistical Applications and Methods
    • /
    • v.2 no.1
    • /
    • pp.137-144
    • /
    • 1995
  • Hierarchical Bayes estimations of exchangeable mean vector of a multivariate Poisson distribution are obtained. Since sophiscated analytic integration procedures are needed, the Laplace method is employed in order tocompute these estimations approximately. An example is presented.

  • PDF

A comparison of group sequential methods in clinical trials (임상실험에서 그룹축차방법들의 비교)

  • 서의훈;안성진;임동훈
    • The Korean Journal of Applied Statistics
    • /
    • v.10 no.2
    • /
    • pp.353-366
    • /
    • 1997
  • In this paper, we derive an approximate optimal Bayes group sequential design for a given loss function. We use the Monte-Carlo method to compare the ASN(average sample size) function and Bayes risk of approximate optimal Bayes group sequential design, Pocock design and O'Brien and Fleming design. Also introduced is the concept of Bayes efficiency and percentage loss of information due to grouping for the group sequential design and use it to measure the loss of information for different group sizes.

  • PDF

Development of Algorithms for Sorting Peeled Garlic Using Machnie Vison (I) - Comparison of sorting accuracy between Bayes discriminant function and neural network - (기계시각을 이용한 박피 마늘 선별 알고리즘 개발 (I) - 베이즈 판별함수와 신경회로망에 의한 설별 정확도 비교 -)

  • 이상엽;이수희;노상하;배영환
    • Journal of Biosystems Engineering
    • /
    • v.24 no.4
    • /
    • pp.325-334
    • /
    • 1999
  • The aim of this study was to present a groundwork for development of a sorting system of peeled garlics using machine vision. Images of various garlic samples such as sound, partially defective, discolored, rotten and un-peeled were obtained with a B/W machine vision system. Sorting factors which were based on normalized histogram and statistical analysis(STEPDISC Method) had good separability for various garlic samples. Bayes discriminant function and neural network sorting algorithms were developed with the sample images and were experimented on various garlic samples. It was showed that garlic samples could be classified by sorting algorithm with average sorting accuracies of 88.4% by Bayes discriminant function and 93.2% by neural network.

  • PDF

A Bayes Test for Equality of Intra-Subject Variabilities in 2$\times$2 Crossover Design

  • Oh, Hyun-Sook
    • Communications for Statistical Applications and Methods
    • /
    • v.7 no.2
    • /
    • pp.541-548
    • /
    • 2000
  • Various statistical methods for assessment of equivalence in average bioavailabilities have been developed under the assumption that the intra-subject variabilities for the test and reference formulations are the same. Without the assumption, assessing the equivalence in average bioavailabilites does not imply that the two formulations are therapeutically equivalent and exchangeable. The most commonly used test procedure for equality of variabilites in 2$\times$2 crossover experiment is the so called Pitman-Morgan's adjusted F test based on the model without carryover effects (Chow and Liu(1992)). In this paper, a Bayesian method based on the Intrinsic Bayes Factor is proposed, which can be applied to the model with carryover effects.

  • PDF

Standard Error of Empirical Bayes Estimate in NONMEM$^{(R)}$ VI

  • Kang, Dong-Woo;Bae, Kyun-Seop;Houk, Brett E.;Savic, Radojka M.;Karlsson, Mats O.
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.16 no.2
    • /
    • pp.97-106
    • /
    • 2012
  • The pharmacokinetics/pharmacodynamics analysis software NONMEM$^{(R)}$ output provides model parameter estimates and associated standard errors. However, the standard error of empirical Bayes estimates of inter-subject variability is not available. A simple and direct method for estimating standard error of the empirical Bayes estimates of inter-subject variability using the NONMEM$^{(R)}$ VI internal matrix POSTV is developed and applied to several pharmacokinetic models using intensively or sparsely sampled data for demonstration and to evaluate performance. The computed standard error is in general similar to the results from other post-processing methods and the degree of difference, if any, depends on the employed estimation options.