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Serum level changes of long chain-polyunsaturated fatty acids in patients undergoing periodontal therapy combined with one year of omega-3 supplementation: a pilot randomized clinical trial

  • Martinez, Gisele Lago;Koury, Josely Correa;Martins, Marcela Anjos;Nogueira, Fernanda;Fischer, Ricardo Guimaraes;Gustafsson, Anders;Figueredo, Carlos Marcelo S.
    • Journal of Periodontal and Implant Science
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    • v.44 no.4
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    • pp.169-177
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    • 2014
  • Purpose: We aimed to investigate the impact of nonsurgical periodontal treatment combined with one-year dietary supplementation with omega (${\omega}$)-3 on the serum levels of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and arachidonic acid (AA). Methods: Fifteen patients with chronic generalized periodontitis were treated with scaling and root planing. The test group consisted of seven patients ($43.1{\pm}6.0$ years) supplemented with ${\omega}$-3, consisting of EPA plus DHA, three capsules, each of 300 mg of ${\omega}$-3 (180-mg EPA/120-mg DHA), for 12 months. The control group was composed of eight patients ($46.1{\pm}11.6$ years) that took a placebo capsule for 12 months. The periodontal examination and the serum levels of DPA, EPA, DHA, and AA were performed at baseline (T0), and 4 (T1), and 12 (T2) months after therapy. Results: In the test group, AA and DPA levels had been reduced significantly at T1 (P<0.05). AA and EPA levels had been increased significantly at T2 (P<0.05). The ${\Delta}EPA$ was significantly higher in the test compared to the placebo group at T2-T0 (P=0.02). The AA/EPA had decreased significantly at T1 and T2 relative to baseline (P<0.05). Conclusions: Nonsurgical periodontal treatment combined with ${\omega}$-3 supplementation significantly increased the EPA levels and decreased the AA/EPA ratio in serum after one year follow-up. However, no effect on the clinical outcome of periodontal therapy was observed.

The Effects of Mental Practice for Performing of Functional Activities to Unilateral Neglect and ADL in Person With Stroke (기능적 활동의 수행에 대한 상상연습이 뇌졸중 환자의 편측무시와 일상생활활동에 미치는 효과)

  • Choi, Yoo-Im
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.12
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    • pp.3879-3887
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    • 2009
  • The purpose of this study was to investigate the effect of mental practice about functional performance of affected limb to unilateral neglect and ADL(Activities of Daily Living) in person with stroke. A single subject experimental research with ABA design was employed in this study. The experiment formed 18 sessions in total: 5 sessions for baseline, 10 sessions for mental practice treatment, and 3 sessions for the second baseline. Mental practice was composed of performing 3 functional activities(dressing clothes, make-up with materials and arrangement, folding clothes). It took 5 minutes at once and 15 minutes in total daily. The unilateral neglect was measured by reading test, writing test, and Baking Tray Task. ADL was assessed by COPM. The results indicated that unilateral neglect test scores were all reduced, and the score of COPM was clinically significant. Mental practice for performing of functional activities was effective method to reduce unilateral neglect and improve ADL in person with stroke.

Throughput Improvement and Power-Interruption Consideration of Fly-By-Wire Flight Control Computer (비행제어 컴퓨터의 Throughput 향상 및 Power-Interuption 대처 설계)

  • Lee, Cheol;Seo, Joon-Ho;Ham, Heung-Bin;Cho, In-Je;Woon, Hyung-Sik
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.10
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    • pp.940-947
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    • 2007
  • For the performance upgrade of a supersonic jet fighter, the processor and FLCC(Flight Control Computer) Architecture were upgraded from a baseline FLCC. Prior to the hardware implementation phase, the exact CPU throughput estimation is necessary. For this purpose, an experimental method for new FLCC throughput estimation was introduced in this study. While baseline FLCC operating, the CPU address bus was collected with logic analyzer, and then decoded to get the exact access times to each memory-memory and the number of program Instruction branches. Based on these data, a throughput test in CPU demo-board of the new FLCC configuration was performed. From test results, the CPU-Memory architecture was design-changed before FLCC hardware implementation phase. To check the flight stability degradation due to power-interrupt problem due to CPU-Memory architecture change, the piloted HILS (Hardware-In-the Loop Simulator) test was conducted.

Effect of Proprioceptive Neuromuscular Facilitation and Action Observation Training on Upper Extremity Motor Function in Stroke Patient: A Single-Subject Study (고유수용성신경근 촉진법 훈련과 동작관찰 훈련이 뇌졸중 환자의 상지 운동기능에 미치는 효과: 단일사례 연구)

  • Park, Hye-Ryoung;Lee, Moon-Kyu;Yun, Tae-Won
    • Physical Therapy Korea
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    • v.22 no.1
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    • pp.69-78
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    • 2015
  • This study evaluated and compared the effectiveness on upper motor extremity function between proprioceptive neuromuscular facilitation which has been frequently used in clinical practice, and action observation training in terms of improving upper motor extremity function. A study with a single-subject design (A-B-C-A') was conducted with a patient who was diagnosed with left hemiplegia. A repeated-measure analysis was conducted to assess results of the Wolf Motor Function Test (WMFT), Box and Block Test (BBT), and grip and pinch strength test performed daily in the study for 4 weeks. The results of the analysis indicated that the WMFT score, BBT score, grip strength, and pinch strength were improved from 29.60 to 39 (24.10%), from 1.67 to 4.93 each (EA) (66.22%), from 2.06 to 2.66 libras (lbs) (22.61%), and from 1.57 to 1.93 lbs (18.94%), respectively, from the baseline period to treatment period B. The values were improved from 29.60 to 42.20 (29.86%), from 1.67 to 7 EA (76.21%), from 2.06 to 3.47 lbs (40.57%), and from 1.57 to 1.67 lbs (6.12%), respectively, from the baseline period to treatment period C. From treatment period B to treatment period C, the WMFT score, BBT score, and grip strength were improved from 39 to 42.20 (7.58%), from 4.93 to 7 EA (29.56%), and from 2.66 to 3.47 lbs (23.20%), respectively, but pinch strength was decreased from 1.93 to 1.67 lbs (15.83%). In conclusion, proprioceptive neuromuscular facilitation and action observation training both have positive effects on upper extremity motor function. However, we suggest that the posttreatment effect of action observation training was better than that of proprioceptive neuromuscular facilitation.

Preservation of keratinized mucosa around implants using a prefabricated implant-retained stent: a case-control study

  • Kim, Chang-Soon;Duong, Hieu Pham;Park, Jung-Chul;Shin, Hyun-Seung
    • Journal of Periodontal and Implant Science
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    • v.46 no.5
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    • pp.329-336
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    • 2016
  • Purpose: The aim of this study was to clinically assess the impact of a prefabricated implant-retained stent clipped over healing abutments on the preservation of keratinized mucosa around implants after implant surgery, and to compare it with horizontal external mattress sutures. Methods: A total of 50 patients were enrolled in this study. In the test group, a prefabricated implant-retained stent was clipped on the healing abutment after implant surgery to replace the keratinized tissue bucco-apically. In the control group, horizontal external mattress sutures were applied instead of using a stent. After the surgical procedure, the width of the buccal keratinized mucosa was measured at the mesial, middle, and distal aspects of the healing abutment. The change in the width of the buccal keratinized mucosa was assessed at 1 and 3 months. Results: Healing was uneventful in both groups. The difference of width between baseline and 1 month was $-0.26{\pm}0.85mm$ in the test group, without any statistical significance (P=0.137). Meanwhile, the corresponding difference in the control group was $-0.74{\pm}0.73mm$ and it showed statistical significance (P<0.001). The difference of width between baseline and 3 months was $-0.57{\pm}0.97mm$ in the test group and $-0.86{\pm}0.71mm$ in the control group. These reductions were statistically significant (P<0.05); however, there was no difference between the 2 groups. Conclusions: Using a prefabricated implant-retained stent was shown to be effective in the preservation of the keratinized mucosa around implants and it was simple and straightforward in comparison to the horizontal external mattress suture technique.

A comparative study of clinical effects following treatment of class II furcations using allograft and PR with and without bioabsorbable membrane (2급 이개부 병변을 동종골과 혈소판 농축 혈장으로 치료시 차폐막 사용에 따른 임상적 효과의 비교 연구)

  • Park, Soon-Jae;Lim, Sung-Bin;Chung, Chin-Hyung
    • Journal of Periodontal and Implant Science
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    • v.32 no.3
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    • pp.631-642
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    • 2002
  • The present study evaluated of regeneration effect of platelet rich plasma on the treatment of classII furcation involvement, with allograft in humans. The control was treated without bioabsorbable membrane, and the test was treated with bioabsorbable membrane. Pocket depth, clinical attachment level, and gingival recession were measured at baseline, postoperative 3, 6months. Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Mann-whitney Test using SPSS program (5% significance level). The results were as follows: 1. The change of pocket depth and clinical attachment level in both groups was decreased significantly at 3, 6months.(p<0.05) 2. The change of gingival recession in both groups was increased significantly at 3, 6months than at baseline.(p (0.05) 3. The change of pocket depth and clinical attachment level in both groups was increased significantly at 3, 6months, but there were no statistically or clinically significant differences with both groups. 4. The change of gingival recession in both groups was increased significantly at 3, 6months, but there were no statistically or clinically significant differences with both groups. 5. The significant reduction of the pocket depth and clinical attachment level exhibited marked changes at 3 months in both groups. In conclusion, the results of this study suggest that there are no statistically or clinically significant differences between with and without bioabsorbable membrane on treatment of classII furcations using allograft and PRP

The Effect of Balance Task-Related Circuit Training on Chronic Stroke Patients (뇌졸중 환자의 균형 향상 과제 중심 순환 훈련의 효과)

  • Lee, Han-Suk;Kim, Myung-Chul
    • The Journal of Korean Physical Therapy
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    • v.21 no.4
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    • pp.23-30
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    • 2009
  • Purpose: This study investigated the efficacy of task-related circuit training aimed at improving balance in individuals discharged from rehabilitation facilities following a stroke. Methods: We recruited 12 stroke patients (34-66 years of age) to participate in a task-related circuit training program. Baseline assessment included a history of stroke and an assessment using the Mini-Mental State Examination Korea (MMSE-K). After a baseline assessment, follow-up assessments were administered pre- and post-training. These included Berg Balance Scale (BBS), Functional Reach Test (FRT), and the Time Up & Go Test (TUG). Physiotherapists trained study subjects under the one-to-one supervision of students from the department of physical therapy. Circuit class study participants attended 90-minute treatment sessions, one day a week for 12 weeks (from September to December 2008). The program consisted of a light warm-up period (10 min), physical exercises for improving balance (20 min), tasks focused on improving balance (50 min) and a cool-down period (10 min). Results: Scores for the BBS assessment increased significantly (from 43.2 to 49.7) after the training (p<0.05). Reach distance on the FRT increased substantially (from 27.7 cm to 47.0 cm), although the improvement was not significant (p>0.05). The average time on the TUG test decreased significantly (from 23.7 sec to 19.5 sec) after the training (p<0.05). Conclusion: The task-related circuit training program improved the balance and mobility of subjects, indicating that such a group program is useful for stroke patients who are discharged from the hospital. More such task-related programs set in a community environment should be developed.

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Effects of a warmed blanket for the relieving of cold discomfort after Cesarean Section (저온불편감 완화를 위한 가온담요의 효과 - 제왕절개술 산모를 대상으로 -)

  • Jung Hyang-Mee;Kim Myung-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.7 no.1
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    • pp.16-29
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    • 2000
  • The purpose of this study was to examine the effects of a warmed blanket on relieving the cold discomfort after Cesarean Section delivery. A nonequivalent control group pre-test/post-test design was used for this quasi-experimental study. Sixty women were recruited for this study and divided by two groups: experimental and control groups. Blankets warmed to $40^{\circ}C$ were applied to the women in the experimental group for one hour and unwarmed blankets were applied to the control group. Using Abbey's shivering scales, subjective thermal sensation score, and Celsius mercury thermometer, cold discomfort was measured at four time points: 1) baseline measure (at the point the blanket was applied) 2) 15 min. later, 3) 30 min. later, and 4) 45 min. after application. Data were analyzed using SPSS/WIN and t-test and MANOVA were used to examine the effects of the warmed blanket for relieving cold discomfort. The results of the study are as follows. The experimental group had less cold discomfort than the control group(Wilts's value =0.580, p=0.000) at the 45 minute point after blanket application. the Experimental group reported less shivering and subjective thermal sensation than the control group. Shivering scores showed significant differences between the two groups at each of the four time points (baseline, 15 min., 30 min., and 45 min.) and subjective thermal sensation score showed significant differences between two groups at 45 minutes. after blanket application. In conclusion, the application of a warmed blanket was more effective on shivering and subjective thermal sensation than body temperature measured by objective means. Because women in this study were in the normal range of body temperature, differences in the objective body temperature between the two groups may not be sensitive enough to be detected. Even though differences in objective body temperature were not found, reduced subjective discomfort for low body temperature may be a sufficient significant finding in for nurse clinicians to utilize this method on their practice. Further studies in this area are needed to support these findings.

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Clinical Study of Tetracycline HCl Conditioning in the Treatment of Gingival Recession. A Comparative Study (치근 피개 술식시 치근에 도포된 테트라사이클린의 효과에 관한 임상적 연구)

  • Kim, Jong-Ae;Chung, Chin-Hyung;Lim, Sung-Bin
    • Journal of Periodontal and Implant Science
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    • v.30 no.1
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    • pp.133-146
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    • 2000
  • Histological studies indicate a tetracycline HCl similar to citric acid to induce connetive tissue repair in animals. When tetracycline HCl was used as a root conditioning agent in humans, there was a trend toward more connective tissue attachment than in root planing alone. The purpose of this study was to evaluate clinical effect of tetracycline HCl in the treatment of gingival recession. 44 teeth in 12 patients with bilaterally gingival recession & Miller classification I, II gingival recession were selected and 22 teeth were treated with 125mg/ml tetracycline HCl , the others was not treated with tetracycline HCl. Gingival recession, pocket depth, clinical attachment level, width of keratinized gingiva were observed at baseline, postoperative 4, 12, 20weeks. Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Wilcoxon's rank sum test(Mann-whitney test) using SPSS program.(5% significance level) The results were as follows: 1........The change of gingival recession, clinical attachment level, keratinized gingiva in both groups were increased significantly at 4, 12, 20 weeks. 2.......The pocket depth exhibited no marked changes throughout the entire investigation in both groups. 3........The change of gingival recession in tetracycline group was increased significantly than control group at 4, 12, 20 weeks and the percentage of root coverage was 93% in tetracycline group and 83% in control group. 4........The change of clinical attachment level, pocket depth, keratinized tissue from baseline to 4, 12, 20 weeks was not differ significanltly in both group.

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Low-level Laser Therapy with Novel Array of Light Source and Individualized Program for Treatment of Androgenetic Alopecia: A 16-week, Randomized, Double-blind, Sham Device-controlled Study

  • Kim, Jee-Woo;Kwon, Yeo-Seon;Chang, Yoon-Young;Hong, Sung-Ho;Shin, Jung-Won;Na, Jung-Im;Huh, Chang-Hun
    • Medical Lasers
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    • v.9 no.2
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    • pp.150-158
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    • 2020
  • Background and Objectives Low-level laser therapy (LLLT) is used widely to promote hair growth in androgenetic alopecia (AGA). This study examined the clinical efficacy and safety of a home-use LLLT device with a newly designed array of light sources and software optimized for individual types of AGA. Materials and Methods The study was a randomized, double-blind, sham device-controlled trial. Forty-eight subjects (39 men and nine women) were assigned randomly in a 2:1 ratio to use either the test device (LG Pra'L HGN1, LG electronics, Korea) or sham device. The subjects used the LLLT device three times a week for 16 weeks. Phototrichogram was used to measure the hair density and hair thickness at 0, 8, and 16-weeks. Adverse events were closely monitored. Results After 16 weeks of using the device, the test group showed a significant increase in hair density and hair thickness compared to the control. In the test group, the hair density increased 6.96 counts/cm2 at eight weeks and 13.67 counts/cm2 at 16 weeks from the baseline. The hair thickness increased 7.21 ㎛ at eight weeks and 11.80 ㎛ at 16 weeks compared to the baseline. Conclusion The home-use LLLT device with a novel array of light sources and an individualized program according to the types of hair loss appears to be an effective and safe treatment modality for both male and female AGA patients.