• 제목/요약/키워드: Base deficit

검색결과 45건 처리시간 0.021초

두부손상을 동반한 다발성 외상환자에서 중증도 평가지표로서 염기결핍의 유용성 (Usefulness of the Base Deficit as an Injury-severity Indicator in Multiple-trauma Patients with Head Injuries)

  • 김봉주;강태경;최승운;김혜진;오성찬;조석진;류석용
    • Journal of Trauma and Injury
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    • 제25권4호
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    • pp.223-229
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    • 2012
  • Purpose: The arterial base deficit and the serum lactate level are widely recognized indicators of injury severity, adequacy of resuscitation and outcome. The purpose of this study is to evaluate the usefulness of the arterial base deficit as an injury-severity indicator in multiple-trauma patients with head injuries. Methods: Data were retrospectively collected from trauma patients over 18 years of age who had been admitted at the emergency center between October 2005 and July 2006. The patients were divided into head-injury and non-head-injury groups. These patients were then sub-divided into minor ($$ISS{\leq_-}15$$)-injury and major ($$ISS{\geq_-}16$$)-injury groups according to their injury severity scores (ISS). We analyzed the differences in the base deficits and the serum lactate levels between the major- and the minor-injury sub-groups in both the head-injury and the non-head-injury groups. Results: In the non-head-injury group, we found statistically significant differences in the arterial base deficit between the major-injury and the minor-injury sub-groups($-6.86{\pm}2.40mmol/L$ vs. $-1.37{\pm}0.73mmol/L$, p=0.010). In the head-injury group, no significant differences were noted between the two sub-groups($-2.50{\pm}1.28mmol/L$ vs. $-1.51{\pm}0.74mmol/L$, p=0.897). Moreover, the differences in arterial base deficit between the major-injury and the minor-injury sub-groups were not significant both for either single-head-trauma or multiple-head-trauma patients (p=0.643 vs. p=0.832). Conclusion: We conclude that neither the arterial base deficit nor the serum lactate level can be used to predict injury severity in multiple-trauma patients with head injuries.

외상환자의 초기 사망 예측 지표로서의 내원 초기의 염기 결핍, 젖산 및 강이온 차이의 유용성 비교 (The Comparison of Base Deficit, Lactate, and Strong Ion Gap as Early Predictor of Mortality in Trauma Patients)

  • 박경혜;이강현;김선휴;오성범;문중범;김현;황성오;김헌주
    • Journal of Trauma and Injury
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    • 제18권2호
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    • pp.127-134
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    • 2005
  • Purpose: Currently, there is a variety of systems available for predicting prognosis of trauma patients such as trauma score, Injury severity score (ISS) and acid-base variables. But it is not clear that the initial acid-base variables are predictors of prognosis in trauma patients at the emergency department. The objective of this study is to compare the base deficit, lactate and strong ion gap as an early predictor of mortality in trauma patients. Methods: Retrospective record review of 136 trauma patients needed to admit to intensive care unit via emergency department (June 2004 to February 2005). Data included age, injury mechanism, ISS, Revised trauma score (RTS), Multiple organ dysfunction score (MODS), Acute physiology and chronic health evaluation III (APACHE III), Glasgow coma scale (GCS), laboratory profiles, calculated anion gap and strong ion gap. Patients were divided into survivors and non-survivors, shock group and non-shock group with comparison by t-test;significance was assumed for p<0.05. Correlation between acid-base variables and mean arterial blood pressure (MABP) was evaluated. Results: There was a significant difference between the RTS (p=0.00), APACHE III (p=0.00), MODS (p=0.00), GCS (p=0.00) of survivors and non-survivors. There was no significant difference between the ISS (p=0.082), lactate (p=0.541), base excess (p=0.468) and SIG (p=0.894) of survivors and non-survivors. There was a significant difference between the RTS (p=0.023), APACHE III (p=0.002), lactate (p=0.000), base excess (p=0.000) and SIG (p=0.000) of shock and non-shock group. There was no significant difference between the ISS (p=0.270), MODS (p=0.442) and GCS (p=0.432) of shock and non-shock group. The base excess was most correlated to MABP (r2=0.150). Conclusion: Initial base deficit, serum lactate and SIG are not predictors of mortality in moderate to severe trauma patients. Initial base deficit, serum lactate and SIG are correlated with the mean arterial blood pressure in trauma patients in emergency department.

성인 중증 중독환자 예측을 위한 새로운 지표 개발: aBIG score for poisoning (Application of Poisoning aBIG score for Prediction of Fatal Severity in Acute Adult Intoxications)

  • 최마이클승필;안재윤;강인구;이미진
    • 대한임상독성학회지
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    • 제12권1호
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    • pp.14-21
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    • 2014
  • Purpose: The objective of this study was to develop a new scoring tool that is comprehensively applicable and predicts fatality within 24 h of intoxication. Methods: This was a cohort study conducted in two emergency medical centers from 2011 to 2012. We identified factors associated with severe/fatality. Through a discriminant analysis, we devised the aBIG (age, Base deficit, Infection, and Glasgow coma scale) score. To compare the ability of aBIG to predict intoxication severity with that of previous scoring systems such as APACHE II, MODS, SAPS IIe, and SOFA, we determined the receiver operating characteristic curves of each variable in predicting severe-to-fatal toxicity. Results: Compared with the mild/moderate toxicity group (n=211), the severe/fatal group (n=143) had higher incidences of metabolic acidosis, infection, serious mental change, QTc prolongation and hepato-renal failure. Age, base deficit, infection-WBC count, and Glasgow Coma Scale were independently associated with severe/fatal poisoning. These variables were combined into the poisoning "aBIG" score [$0.28{\times}$Age group+$0.38{\times}WBC$ count/$10^3+0.52{\times}$Base deficit+$0.64{\times}$(15-GCS)], which were each calculated to have an area under the curve of 0.904 (95% confidence interval: 0.868-0.933). The aBIG poisoning score had an equivalent level of severity predictability as APACHE II and a superior than MODS, SOFA, and SAPS IIe. Conclusion: We developed a simplified scoring system using the four variables of age, base deficit, infected leukocytosis, and GCS. The poisoning aBIG score was a simple method that could be performed rapidly on admission to evaluate severity of illness and predict fatal severity in patients with acute intoxications.

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둔상성 중증 외상환자에서 내원 초기에 시행한 동맥혈 염기결핍과 예후의 관계 (The Usefulness of the Admission Base Deficit as a Marker of Mortality in Severely Injured Patients with Blunt Trauma)

  • 유병철;정민;이길재;이정남
    • Journal of Trauma and Injury
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    • 제26권1호
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    • pp.1-5
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    • 2013
  • Purpose: The base deficit (BD) at admission in severely injured patients has been shown to predict the adequacy of resuscitation and outcome, but this relationship is not well established in the Korean experience. The purpose of this study was to define the association between arterial blood gas (ABG) values and the mortality for patients with severe blunt trauma at a developing trauma center in Korea. Methods: A retrospective review of 415 adult patients with severe blunt trauma was conducted using electronic medical records from Jan. 2010 to Dec. 2011. Results: A total of 256 patients had ABG drawn within 1 hour of arrival. Patients who expired displayed a higher lactate level (4.86 vs. 3.31, p<0.0001), a worse BD (-7.99 vs. -5.37, p=0.001), and a lower pH (7.31 vs. 7.34, p=0.011) at arrival compared with those who survived. A statistically significant association was also observed between BD and blood product usage (p=0.001). Conclusion: The base deficit at admission is a useful marker of mortality and outcome in severely injured patients with blunt trauma in Korea.

Drag reduction of a circular cylinder at subcritical flow regime using base shield plates

  • El-Khairy, Nabil A.H.
    • Wind and Structures
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    • 제6권5호
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    • pp.347-356
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    • 2003
  • Experimental studies on drag reduction of a circular cylinder of diameter D were conducted in the subcritical flow regime at Reynolds numbers in the range $4{\times}10^4{\leq}Re{\leq}10^5$. To shield the cylinder rear surface from the pressure deficit of the unsteady vortex generation in the near wake, two shield plates were attached downstream of the separation points to form a cavity at the base region. The chord of the shield plates, L, ranged from 0.22 to 1.52 D and the cavity width, G, was in the range from 0 to 0.96 D. It is concluded that significant drag reductions from that of a plain cylinder may be achieved by proper sizing of the shield plates and the base cavity. The study shows that using a pair of shield plates at G/D of 0.86 and angular position ${\theta}$ of ${\pm}121^{\circ}$ results in a configuration with percentage drag reduction of 40% for L/D of 0.5, and 55% for L/D of 1.0.

내원 초기에 측정한 외상환자의 동맥혈 염기결핍의 유용성 (The Usefulness of Initial Arterial Base Deficit in Trauma Patients)

  • 이은헌;최재영;최영철;황성연
    • Journal of Trauma and Injury
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    • 제19권1호
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    • pp.67-73
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    • 2006
  • Purpose: The arterial base deficit (BD) has proven to be useful in the evaluation and management of trauma patients. Indicators such as the Triage-Revised Trauma Score (t-RTS) and the systemic inflammatory response syndrome (SIRS) score have been used as triage tools for emergency trauma patients in Korea. The purpose of this study was to assess the usefulness of the initial BD in predicting injury severity and outcome in the trauma population. Methods: The medical records of 308 consecutive trauma patients admitted to the Emergency Center of Masan Samsung Hospital from January 2004 to December 2004 were carefully examined prospectively and retrospectively, and 291 patients were selected as subjects for this research. The SIRS score and the t-RTS were calculated based on the records from the emergency department, and the BD was calculated based on the arterial blood gas analysis obtained within 30 minutes of admission. The efficiency of the three indicators as triage tools was evaluated by using cross tabulations in two - by - two matrices and by using a receiver operating characteristic (ROC) curve analysis. Results: When the mortality was used as the outcome parameter, the sensitivity and the accuracy of the initial BD were higher than those of the SIRS score (p<0.05) and were same as those of the t-RTS. The areas under the ROC curves of the initial BD, the SIRS score, and the t-RTS were $0.740{\pm}0.087$, $0.696{\pm}0.082$, and $0.871{\pm}0.072$, respectively (95% confidence interval). When emergency operation and blood transfusion requirements were used as outcome parameters, the comparisons of the sensitivities and the accuracies of the initial BD and the other two indicators showed the same pattern as mentioned above. The areas under the ROC curves of the initial BD were 0.7~0.8 and were larger than those of the SIRS score (p<0.05). Conclusion: The ability of the initial BD to predict injury severity and outcome was similar to those of the t-RTS and the SIRS score. Therefore, the authors suggest that the initial BD may be used as an alternative to previous triage tools for trauma patients.

외상성 복부 장기 손상 및 골반 손상에 의한 혈복강으로 동맥 색전술을 시행 받은 환자에서 예후 인자 (Prognostic Factors in Patients Who Performed Angiographic Embolization for the Bleeding from Injury of the Intraabdominal Organ and Pelvic Area)

  • 이진호;장지영;심홍진;이재길
    • Journal of Trauma and Injury
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    • 제25권4호
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    • pp.166-171
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    • 2012
  • Purpose: In patients with traumatic hemoperitoneum or pelvic bone fracture who underwent angiography and embolization, we want to find the prognostic factors related with mortality. Methods: Patients(333 patients) who visited our hospital with traumatic injury from March 2008 to April 2012 were included in this study. Only 37 patients with traumatic hemoperitoneum or pelvic bone fracture underwent angiography and embolization. A retrospective review was conducted, and Glasgow coma scale (GCS), Revised trauma score (RTS), Injury severity score (ISS), initial laboratory finding and time interval, the amount of transfusion from the arrival at the ER to the start of embolization, and the vital signs before and after procedure were checked. Stastical analysis was conducted using the Chi square and Mann-Whitney U test. Results: In univariate analysis, the amount of transfusion, the base deficit before procedure, the systolic blood pressure before and after the procedure, the GCS, the RTS and the ISS were significantly associated with prognosis. In the multivariate analysis, the ISS and the base deficit had significant association with prognosis. Of the 37 patients who underwent angiography and embolization, 31 patients needed not additional procedure (Group A) while the other 6 patients needed an additional procedure (Group B). After procedure, a statistically significant higher blood pressure was observed in Group A than in Group B. As to the difference in blood pressure before and after the procedure, a statistically significant decrease in systolic blood pressure was observed in Group B, but an increase was observed in Group A. Conclusion: In traumatic hemoperitoneum or pelvic bone fracture patients who underwent angiography and embolization, GCS, ISS, RTS, transfusion amount before the procedure, initial base deficit and systolic blood pressure were factors related to mortality. When patients who underwent angiography and embolization only were compared with patients who underwent re-embolization or additional procedure after the first embolization, an increase in systolic blood pressure after embolization was a prognostic factor for successful control of bleeding.

수도권 전압안정도 향상을 위한 100MVA STATCOM 위치선정 연구 (The Site Selection of 100MVA STATCOM for Voltage Stability Enhancement in Korean Metropolitan Area)

  • 장병훈;김수열;한정열;최돈근;송화창;이병준
    • 전기학회논문지
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    • 제56권9호
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    • pp.1543-1548
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    • 2007
  • This paper reports a study on determination of the adequate location of 100 MVA STATCOM regarding the transfer capability enhancement on the metropolitan interface as well as the economy in system operation. The base case in the study was established considering a scenario of the energy support to North Korea from the KEPCO (Korea Electric Power Corporation) system through a HVDC interconnection. In the base case, the energy support was approximately modeled with a load of 1500 MW, and by the load addition, the system was weakened in terms of voltage stability and transfer capability. After a thorough investigation on the case, the location of the STATCOM was decided to compensate the reactive deficit of the modified system and to maximize the operational benefit which can be estimated by FV analysis.

외상성 비장 손상 환자의 치료방법의 선택: 단일 기관 연구 (The Choice of Management in Patients with Splenic Blunt Trauma : A Single Center Study)

  • 장지영;이승환;이재길
    • Journal of Trauma and Injury
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    • 제26권4호
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    • pp.280-285
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    • 2013
  • Purpose: Nowadays, non-operative management increases in patients with blunt splenic injury due to development of diagnostic and interventional technique. The purpose of this study is to evaluate the management in patients with blunt splenic injury and effect of clinical state such as shock on the choice of management. Methods: From April 2007 to July 2013, we retrospectively reviewed the medical charts of fifty patients who had splenic injury after blunt trauma. The demographic characteristics, American Association for the Surgery of Trauma (AAST) grade of splenic injury, management method (emergency operation, angiographic embolization or observation) and clinical outcome were analyzed. Results: The mean age was $41.5{\pm}21.4$ years and male was 44(88%). Twenty patients(40%) were in shock condition initially and five patients(10%) underwent emergency operation due to hemodynamic instability. Emergency angiographic embolization was performed in 20 patients(40%) and 25 patients were managed conservatively. When patients were divided into shock group (SG) and non-shock group (NSG), Patients in SG had significantly higher serum lactate level and base deficit than NSG (lactate; $4.5{\pm}3.4$ mmol/L, base deficit; $5.8{\pm}4.4$ mmol/L vs $1.9{\pm}1.4$ mmol/L, $2.8{\pm}2.5$ mmol/L, p=0.007, p=0.013). There was no significant difference of AAST grade and contrast blush rate in abdomen CT between two groups. Among 45 patients with non-operative management, four patients(8.9%) got delayed angiographic embolization and 3 patient died from companied organ injury. Conclusion: Non-operative management can be acceptable management option in patients with splenic blunt trauma under intensive hemodynamic monitoring.

기상학적 가뭄, 농업 가뭄 및 빅데이터 현장가뭄간의 상관성 평가 (Evaluation of the Relationship between Meteorological, Agricultural and In-situ Big Data Droughts)

  • 이지완;장선숙;안소라;박기욱;김성준
    • 한국지리정보학회지
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    • 제19권1호
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    • pp.64-79
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    • 2016
  • 본 논문의 목적은 SPI 기상학적 가뭄지수, 농업용 저수지 저수율, 농업가뭄 빅데이터간의 관계를 평가함으로써 빅데이터의 활용 가능성을 평가하는데 있다. 2014년 1월부터 2015년 9월까지의 장기가뭄을 대상으로, SPI-12개월 가뭄지수, 평년대비 강수부족율, 농업용저수지 저수부족율, 인터넷포털 검색을 통한 농업가뭄 빅데이터를 월단위 도별로 수집 및 분석하였다. SPI-12의 최대 가뭄심도와 최대 저수 부족율이 나타난 시기를 비교한 결과, 전국적으로 2014년은 7월, 2015년은 8월과 9월에 시기를 같이 하면서 발현되었다. 한편, 빅데이터의 도별 최대 발현시기는 2014년 6월과 7월, 2015년은 3월, 6월~9월에 나타나, SPI-12와 저수 부족율의 최대심도보다 2014년은 1개월, 2015년은 여름에 2개월 이르게 나타났다. 이는 빅데이터가 3월부터의 봄가뭄, 6월의 늦장마, 7월의 마른장마에 이어 2015년은 9월까지의 강우량 부족에 따라 기상학적 가뭄과 농업가뭄에 민감하게 반응하는 것을 의미하며, 농업가뭄관련 빅데이터의 활용이 가뭄의 위험관리에 효과가 있을 것으로 판단된다.