• The Research Journal of the Costume Culture
• /
• v.8 no.3
• /
• pp.374-386
• /
• 2000

This study investigated the relation between seasonal variation of total clothing weight, room, outdoor temperature and basal metabolic rate in man. The basal metabolic rate and total clothing weight, room temperature was determined seasonal for a period of two years and grouped four seasons. Subjects (adults volunteers) who live in seoul and mokpo were compose 120 subject The results were obtained as follows. Seasonal outdoor temperature was difference of seoul and. mokpo. But room temperature in apartments was a little difference than private house. Total-clothing weight is showed seasonal variations at the seoul, private house than at the mokpo, apartment.. The basal metabolic rate is suggested there in gender difference in the basal metabolic rate (P〈.001). The basal metabolic rate increased gradually with the peak of winter sespectively and deceased again todward summer. The difference of between basal metabolic rate in summer and winter was significant room temperature, of seoul and private house, and light total clothing weight.

• The Korean Journal of Physiology
• /
• v.6 no.2
• /
• pp.23-30
• /
• 1972

Contrary to most of European and American investigators failed to find out the seasonal variations of basal metabolic rate in man, Japanese and Korean investigators reported the increase in winter, decrease in summer season. But the causes of variation were not found clearly. To find out whether metabolic acclimatization to climate could be arise or not in human being, the basal metabolic rate was determined monthly for a period of one year in Airmen volunteers who live in Seoul, with 9 l Collins spirometer. The results obtained were as follows: 1. The average ambient temperature was lowest in February $(-5.88^{\circ}C)$ and highest in July $(27.34^{\circ}C)$. 2. Basal metabolic rate was lowest in June and highest in December showing seasonal variations. Interestingly, the increase of basal metabolic rate followed after the drop of ambient temperature below $0^{\circ}C$ (December) and the decrease followed after the elevation of ambient temperature from optimum to hot (June) or cold to warm (March). 3, Mean skinfold thickness increased in spring, decreased in winter. 4. These findings indicate that the basal metabolic rate of Korean reveals the seasonal variation affected by ambient temperature highly.

• Nutritional Sciences
• /
• v.2 no.2
• /
• pp.113-118
• /
• 1999

Critical evaluation of energy intake data from dietary studies is difficult but important. To investigate the underreporting of total energy intake, we analyzed the one-day dietary intake data collected by 24-hour recall method from 550 elderly Koreans aged 60 years or older. Underreporting was addressed by computing the ratio of energy intake (EI) to estimated basal metabolic rate (BMRest). EI : BMRest ratio was found to be 1.38 for, men and 1.33 for women, with about 14% of men and women classified as underreporters. Underreporting of energy intake was highest in men and women who were overweight, had lower family income, or no school education. For men, the most significant variables to predict the ratio of energy intake to estimated basal metabolic. rate (EI : BMRest) were weight status, members of household, alcohol consumption and age, while income and education level were most significant for women.

• Genomics & Informatics
• /
• v.11 no.4
• /
• pp.263-271
• /
• 2013

We investigated the contribution of genetic variations of KLF5 to basal metabolic rate (BMR) and resting metabolic rate (RMR) and the inhibition of obesity in Korean children. A variation of KLF5 (rs3782933) was genotyped in 62 Korean children. Using multiple linear regression analysis, we developed a model to predict BMR in children. We divided them into several groups; normal versus overweight by body mass index (BMI) and low BMR versus high BMR by BMR. There were no differences in the distributions of alleles and genotypes between each group. The genetic variation of KLF5 gene showed a significant correlation with several clinical factors, such as BMR, muscle, low-density lipoprotein cholesterol, and insulin. Children with the TT had significantly higher BMR than those with CC (p=0.030). The highest muscle was observed in the children with TT compared with CC (p=0.032). The insulin and C-peptide values were higher in children with TT than those with CC (p=0.029 vs. p=0.004, respectively). In linear regression analysis, BMI and muscle mass were correlated with BMR, whereas insulin and C-peptide were not associated with BMR. In the high-BMR group, we observed that higher muscle, fat mass, and C-peptide affect the increase of BMR in children with TT (p < 0.001, p < 0.001, and p=0.018, respectively), while Rohrer's index could explain the usual decrease in BMR (adjust $r^2$=1.000, p < 0.001, respectively). We identified a novel association between TT of KLF5 rs3782933 and BMR in Korean children. We could make better use of the variation within KLF5 in a future clinical intervention study of obesity.

• Journal of The Korean Society of Integrative Medicine
• /
• v.8 no.2
• /
• pp.53-61
• /
• 2020

Purpose : We investigated the correlation between body composition and lung function in healthy adults. Methods : This study included 204 healthy adults in whom all measurements were obtained once, and all data were analyzed using the SPSS software for Windows, version 22.0. Pearson's correlation analysis was performed to determine the correlation between body composition (represented by the total body water, protein mass, soft lean mass, mineral mass, basal metabolic rate, fat-free mass, skeletal muscle mass, and body fat percentage) and lung function (represented by the forced vital capacity [FVC], forced expiratory volume in 1 second [FEV₁], the FEV₁/FVC ratio, maximum voluntary ventilation [MVV], maximum expiratory pressure [MEP], and the maximum inspiratory pressure [MIP]). All measurements were obtained by two investigators to improve reliability. A significance level of α=.05 was used to verify statistical significance. Results : Among the lung function measurements obtained in both men and women, the FVC, FEV₁, MVV, and MIP were positively correlated with the total body water, protein mass, soft lean mass, mineral mass, basal metabolic rate, fat-free mass, and skeletal muscle mass in men (p<.05). The FEV₁/FVC ratio was negatively correlated with the total body water, soft lean mass, mineral mass, basal metabolic rate, fat-free mass and the body fat percentage (p<.05). Notably, the FVC, FEV₁, and MVV were positively correlated with the total body water, protein mass, soft lean mass, mineral mass, basal metabolic rate, fat-free mass, and skeletal muscle mass in women (p<.05). Conclusion : This study showed a significant correlation between body composition and lung function in healthy adults. In combination with future studies on lung function, our results can provide objective evidence regarding the importance of prevention of lung disease, and our data can be utilized in rehabilitation programs for patients with respiratory diseases.

• International Journal of Stem Cells
• /
• v.17 no.2
• /
• pp.194-203
• /
• 2024

Evaluating cell metabolism is crucial during pluripotent stem cell (PSC) differentiation and somatic cell reprogramming as it affects cell fate. As cultured stem cells are heterogeneous, a comparative analysis of relative metabolism using existing metabolic analysis methods is difficult, resulting in inaccuracies. In this study, we measured human PSC basal metabolic levels using a Seahorse analyzer. We used fibroblasts, human induced PSCs, and human embryonic stem cells to monitor changes in basal metabolic levels according to cell number and determine the number of cells suitable for analysis. We evaluated normalization methods using glucose and selected the most suitable for the metabolic analysis of heterogeneous PSCs during the reprogramming stage. The response of fibroblasts to glucose increased with starvation time, with oxygen consumption rate and extracellular acidification rate responding most effectively to glucose 4 hours after starvation and declining after 5 hours of starvation. Fibroblasts and PSCs achieved appropriate responses to glucose without damaging their metabolism 2~4 and 2~3 hours after starvation, respectively. We developed a novel method for comparing basal metabolic rates of fibroblasts and PSCs, focusing on quantitative analysis of glycolysis and oxidative phosphorylation using glucose without enzyme inhibitors. This protocol enables efficient comparison of energy metabolism among cell types, including undifferentiated PSCs, differentiated cells, and cells undergoing cellular reprogramming, and addresses critical issues, such as differences in basal metabolic levels and sensitivity to normalization, providing valuable insights into cellular energetics.

• Journal of Korean Medicine for Obesity Research
• /
• v.16 no.2
• /
• pp.116-123
• /
• 2016

Objectives: The purpose of this study was to investigate the effects of modified fasting therapy on the changes of body compositions. Methods: We analyzed the medical records of 33 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University from January 1st, 2011 to December 30th, 2015. They went through reducing food intakes period (7 days), fasting period (14 days) and refeeding period (14 days). Body compositions (weight, body mass index, skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were reviewed at each state. And then the data was analyzed. Results: The body composition values (weight, body mass index [BMI], skeletal muscle mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) decreased during the fasting therapy period, as a whole. The weight, BMI, percent body fat and visceral fat area decreased during the reducing food intakes period, the fasting period and the refeeding period. The skeletal muscle mass and basal metabolic rate significantly decreased during the reducing food intakes period and the fasting period, and insignificantly increased during the refeeding period. Conclusions: Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions.

• The Journal of Korean Physical Therapy
• /
• v.12 no.1
• /
• pp.141-146
• /
• 2000

Making aged exercise by their age it unreasonable because there an differences of personal strength of their body. The three elements which control the aged's possibility of exercising effectivencess are the level of the physical strength in the present state, potential capacities of physical strength and age. Examined the physical strength of aged, the pliancy of body is considerably marked decline by and large and fast twitch muscle are withered. The reason why aged often do prime exercise like and infant. Aged are not fit for the speedy exercise and they can give full scope to their ability by continuing the long time exercise. The reason why aged should dwindle is mainly the retardation of recovering their fatigue which is related to the decline of oxygen activity. Anaerobic energy supply reduction makes aged be bad for severe physical exercise. Basal metabolic rate of rely on physical cellular quantity and people exercising has a high basal metabolic rate because of muscular amount. There were no decline of basal metabolic rate fellowing the age and physical non activiti influences on the atrophy of muscle.

• Journal of Korean Medicine for Obesity Research
• /
• v.3 no.1
• /
• pp.95-105
• /
• 2003

The obesity is the matter of the energy balance in essential. The energy balance in human body is energy expenditure subtracted from energy intake. The energy intake is mainly supplied by carbohydrates, proteins and lipids in food, and the energy expenditure is composed of basal metabolic rate or resting energy expenditure, physical activity and thermogenesis including diet-induced thermogenesis. The resting energy expenditure is measured by direct calorimetry and indirect calorimetry. Generally we can simply use predictive equation with the variables of weight, height, age and fat-free mass to yield metabolic rate. But there is discrepancy between the estimate and real metabolic rate because the equations can not reflect individuality and environments. The resting energy expenditure is influenced by many factors but the fundamental factor is fat-free mass. We briefly reviewed the concept and evaluation of the energy balance, intake and expenditure, which are important parts in the study of obesity. Finally, we surveyed the correlation between metabolic rate and obesity and suggested applicable herb medication to increase metabolic rate.

• Journal of Korean Medicine for Obesity Research
• /
• v.20 no.1
• /
• pp.20-30
• /
• 2020

Objectives: The purpose of this study is to verify the effects of H Gambitang (GB-001) on body composition and basal metabolic rate in pre- and post-menopausal obese woman retrospectively. Methods: The study was conducted on 57 middle-aged obese women. They were divided into two groups; pre-menopausal obesity group (Pr-MOG; n=34) and post-menopausal obesity group (Po-MOG; amenorrhea was continued to 14~48 month, n=23) with no significant difference of age, height, body weight and body mass index. All subjects took herbal medicine 3 times a day, for 6 weeks during treatment period. The weight, height, body fat mass, skeletal muscle mass, and basal metabolic rate of all subjects were measured on first visit. The following measurements were repeated after 2 weeks (2nd), 4 weeks (3rd) and 6 weeks (4th) with Inbody 370 (Biospace) equipment to identify changes of body fat mass, skeletal muscle mass, and basal metabolic rate. Results are represented as mean and standard deviation. Results: Po-MOG showed significantly lower decrease rate in weight reduction on 2~6 weeks while significantly higher decrease rate in skeletal muscle reduction on 4~6 weeks. There were no significant differences between two groups in body fat reduction rate and basal metabolic increasing rate. Conclusions: H Gambitang (GB-001) can be used not only in Pr-MOG but in Po-MOG in weight loss although the effect can be lower in Po-MOG. To prevent skeletal muscle mass loss in Po-MOG, following study on adjusting dose and components of H Gambitang (GB-001) thought to be necessary.