• 신재생에너지
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• 제18권2호
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• pp.73-81
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• 2022

This study was aimed at designing a condenser, as a component of the organic Rankine cycle system for ships. The condenser was manufactured through press molding to achieve a bent shape to enhance the heat transfer performance, considering the shape of the heat transfer plate used in a brazing plate heat exchanger. The heat transfer plate was made of copper-nickel alloy. The required heat transfer rate for the condenser was 110 kW, and the maximum number of layers was set as 25, considering the characteristics of high-temperature brazing. Computational fluid dynamics techniques were used to perform the thermal fluid analysis, based on the ANSYS CFX (v.18.1) commercial program. The heat transfer rate of the condenser was 4.96 kW for one layer (width and length of 0.224 and 0.7 m, respectively) of the heat transfer exchanger. The fin efficiency pertaining to the heat transfer plate was approximately 20%. The heat flow analysis for one layer of the heat exchanger plate indicated that the condenser with 25 layers of heat transfer plates could achieve a heat transfer rate of 110 kW.

• Parasites, Hosts and Diseases
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• 제59권6호
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• pp.547-556
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• 2021

Our objective was to investigate whether inflammatory microenvironment induced by Trichomonas vaginalis infection can stimulate proliferation of prostate cancer (PCa) cells in vitro and in vivo mouse experiments. The production of CXCL1 and CCL2 increased when cells of the mouse PCa cells (TRAMP-C2 cell line) were infected with live T. vaginalis. T. vaginalis-conditioned medium (TCM) prepared from co-culture of PCa cells and T. vaginalis increased PCa cells migration, proliferation and invasion. The cytokine receptors (CXCR2, CCR2, gp130) were expressed higher on the PCa cells treated with TCM. Pretreatment of PCa cells with antibodies to these cytokine receptors significantly reduced the proliferation, mobility and invasiveness of PCa cells, indicating that TCM has its effect through cytokine-cytokine receptor signaling. In C57BL/6 mice, the prostates injected with T. vaginalis mixed PCa cells were larger than those injected with PCa cells alone after 4 weeks. Expression of epithelial-mesenchymal transition markers and cyclin D1 in the prostate tissue injected with T. vaginalis mixed PCa cells increased than those of PCa cells alone. Collectively, it was suggested that inflammatory reactions by T. vaginalis-stimulated PCa cells increase the proliferation and invasion of PCa cells through cytokine-cytokine receptor signaling pathways.

• Journal of Korean Neurosurgical Society
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• 제65권1호
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• pp.13-21
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• 2022

Objective : Nontraumatic subdural hematoma (SDH) is a common disease, and spinal cerebrospinal fluid (CSF) leakage is a possible etiology of unknown significance, which is commonly investigated by several invasive studies. This study demonstrates that heavily T2-weighted magnetic resonance myelography (HT2W-MRM) is a safe and clinically effective imaging modality for detecting CSF leakage in patients with nontraumatic SDH. Methods : All patients who underwent HT2W-MRM for nontraumatic SDH workup at our institution were searched and enrolled in this study. Several parameters were measured and analyzed, including patient demographic data, initial modified Rankin Scale (mRS) score upon presentation, SDH bilaterality, hematoma thickness upon presentation, CSF leakage sites, treatment modalities, follow-up hematoma thickness, and follow-up mRS score. Results : Forty patients were identified, of which 22 (55.0%) had CSF leakage at various spinal locations. Five patients (12.5%) showed no change in mRS score, whereas the remaining (87.5%) showed decreases in follow-up mRS scores. In terms of the overall hematoma thickness, four patients (10.0%) showed increased thickness, two (5.0%) showed no change, 32 (80.0%) showed decreased thickness, and two (5.0%) did not undergo follow-up imaging for hematoma thickness measurement. Conclusion : HT2W-MRM is not only safe but also clinically effective as a primary diagnostic imaging modality to investigate CSF leakage in patients with nontraumatic SDH. Moreover, this study suggests that CSF leakage is a common etiology for nontraumatic SDH, which warrants changes in the diagnosis and treatment strategies.

• 한국자연치유학회지
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• 제10권1호
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• pp.19-25
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• 2021

목적: 본 연구에서 실험대상자들이 삼다수 숲에서 산림욕 후에 타액 코르티솔, 혈관건강 타입 및 혈관건강 지수가 어떻게 변화하는지를 확인하기 위하여 조사하였다. 방법: 삼림에서 걸은 후에 타액의 측정과 심장박동 변이를 측정하여 혈관 상태의 변화를 조사했다. 결과: 삼다수 숲에서 두 시간 동안 산림욕을 한 실험군에서는 타액에 분비되는 스트레스 cortisol 함량은 숲을 방문하기 전보다 유의성 있게 감소하였다(p<.05). 또한 혈관연령 타입은 유의하게 증가하였고(p<.03), 혈관연령 지수는 유의하게 감소하였다(p<.032). 대조군에서는 유의한 결과가 나타나지 않았다. 결론: 제주도 삼다수 숲에서 산림욕이 타액 코르티솔의 감소와 혈관 연령의 증가에 영향을 주어서 건강증진에 효과가 있었다고 평가할 수 있다.

• 한국자연치유학회지
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• 제10권1호
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• pp.33-41
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• 2021

목적: 숲속의 산림욕은 인체의 스트레스 개선에 효과가 있는지를 연구하였다. 제주 삼다수 숲길을 2시간 동안 걸어서 산림욕을 한 후에 맥박과 스트레스 지수의 변화, 자율신경의 변화를 조사하는 것이었다. 방법: 연구는 산림욕 전후에 심장박동 변이와 설문을 통한 조사를 하였다. 결과: 산림욕 후 실험군의 평균 맥박은 유의하게 증가하였다. 스트레스 지수는 실험군에서는 사후에 유의하게 감소하였다. 누적 스트레스, 교감신경 활성(LF), 부교감신경 활성도(HF) 변화 및 LF/HF 비율은 실험군에서는 사후의 측정치의 차이는 있으나, 통계적으로 유의성이 없었다. 설문을 통한 직무 스트레스 평균 지수와 상태 특성 불안 지수의 조사에서는 사후에 유의하게 감소하였다(p<.001). 결론: 삼다수 산림욕이 맥박을 증진하고 스트레스를 감소하는 효과가 입증되어 산림욕이 건강증진에 효과적이라 평가한다.

• Corrosion Science and Technology
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• 제20권6호
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• pp.373-383
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• 2021

The effect of Cr addition to high Mn steel on flow-accelerated corrosion (FAC) behavior in a neutral aqueous environment was evaluated. For comparison, two types of conventional ferritic steels (API X70 steel and 9% Ni steel) were used. A range of experiments (electrochemical polarization and impedance tests, weight loss measurement, and metallographic observation of corrosion scale) were conducted. This study showed that high Mn steel with 3% Cr exhibited the highest resistance to FAC presumably due to the formation of a bi-layer scale structure composed of an inner Cr enriched Fe oxide and an outer Mn substituted partially with Fe oxide on the surface. Although the high Mn steels had the lowest corrosion resistance at the initial corrosion stage due to rapid dissolution kinetics of Mn elements on their surface, the kinetics of inner scale (i.e. Cr enriched Fe oxide) formation on Cr-bearing high Mn steel was faster in dynamic flowing condition compared to stagnant condition. On the other hand, the corrosion scales formed on API X70 and 9% Ni steels did not provide sufficient anti-corrosion function during the prolonged exposure to dynamic flowing conditions.

• Journal of Veterinary Science
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• 제21권4호
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• pp.63.1-63.9
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• 2020

Background: Canine adenovirus type 2 (CAV-2) induces infectious laryngotracheitis in members of the family Canidae, including dogs. To date, no ELISA kits specific for CAV-2 antibody have been commercialized for dogs in Korea. Objectives: We aimed to develop new indirect enzyme-linked immunosorbent assay (I-ELISA) to perform rapid, accurate serological surveys of CAV-2 in dog serum samples. Methods: In total, 165 serum samples were collected from dogs residing in Chungbuk and Gyeongbuk provinces between 2016 and 2018. The Korean CAV-2, named the APQA1701-40P strain, was propagated in Madin-Darby canine kidney cells and purified in an anion-exchange chromatography column for use as an antigen for I-ELISA. The virus-neutralizing antibody titers of CAV-2 in the dog sera were measured by virus neutralization (VN) test. Results: We compared the results obtained between the VN and new I-ELISA tests. The sensitivity, specificity, and accuracy of new I-ELISA were 98.6%, 86.4% and 97.0% compared with VN test, respectively. New I-ELISA was significantly correlated with VN (r = 0.91). Conclusions: These results indicate that new I-ELISA is useful for sero-surveillance of CAV-2 in dog serum.

• Composites Research
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• 제34권6호
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• pp.380-386
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• 2021

본 연구에서는 탄소섬유 강화 복합재료를 적용하여 PTO 샤프트의 임계 속도를 향상시키는 연구를 진행하였다. 탄소섬유 강화 복합재료의 경우 전단 강도가 낮은 단점이 있어, 이를 보완하기 위해 티타늄-탄소섬유 강화 복합재료 하이브리드 구조로 설계하는 것을 제안하였다. PTO 샤프트에서 요구하는 최대 허용 토크, 임계 속도, 비틀림 고유진동수 기준을 충족시키는 최적의 구조를 설계하고 제작하였다. 제작한 PTO 샤프트의 성능 평가를 위해 진동 시험, 정적 비틀림 시험, 비틀림 내구성 시험이 수행되었고, 진동 시험에서 PTO 샤프트의 임계 속도는 20570 rpm로 티타늄 샤프트 대비하여 7.5% 향상된 것을 확인하였다. 또한 정적 비틀림 시험을 통해 PTO 샤프트의 최대 허용 토크가 2300 N·m로 해당 기준을 충족시키는 것을 확인하였다. 최종적으로 11.3~113 N·m 범위의 하중을 반복하는 비틀림 내구성 시험에서도 10⁶ 사이클 동안 피로파괴가 발생하지 않는 것으로 평가되었다.

• 한국동물위생학회지
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• 제45권3호
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• pp.211-219
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• 2022

Bovine viral diarrhea (BVD) is one of the problematic wasting diseases in cattle leading to huge economic losses. This study was conducted to investigate the prevalence of BVD including transient and persistent infection from cattle farms in Gyeongsangnam-do. A total of 2,667 blood samples from 24 farms were collected and the sera were subjected to ELISA to detect BVD virus (BVDV) antigen, E^rns. 5' untranslated region (5'-UTR) of BVDV-positive samples was sequenced to identify the genotype, and compared with isolates previously reported elsewhere. There were fourteen BVDV-positive calves from 2,667 samples (positive rate: 0.52%) from first ELISA testing followed by eight persistently infected out of eleven BVDV-positive samples (72.73%) in secondary ELISA that was conducted in at least four weeks suggesting the circulation of BVDV in the area. Sequencing analysis exhibited that thirteen BVDV-positive samples were identified as BVDV-1b and one sample was BVDV-2a. Phylogenetic analysis revealed that the BVDV-1b-positive samples showed the highest homology in nucleotide sequence to Korean isolates collected from Sancheong, Gyeongsangnam-do, while the BVDV-2a-positive sample (21GN7) was more similar to reference strains collected outside South Korea. This study will provide the recent fundamental data on BVD prevalence in Gyeongsangnam-do to be referred in developing strategies to prevent BVDV in South Korea.

• Journal of Plant Biotechnology
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• 제49권4호
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• pp.271-291
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• 2022

Pectin methylesterase (PME) plays an important role in vegetative and reproductive development and biotic/abiotic stress responses by regulating the degree of methyl-esterification of pectic polysaccharides in the plant cell wall. PMEs are encoded by a large multigene family in higher land plant genomes. In general, the expression of plant PME genes shows tissue- or cell-specific patterns and is induced by endogenous and exogenous stimuli. In this study, we identified PME multigene family members (CsPMEs) from the sweet orange genome and report detailed molecular characterization and expression profiling in different citrus tissues and two fruit developmental stages. We also discussed the possible functional roles of some CsPME genes by comparing them with the known functions of PMEs from other plant species. We identified 48 CsPME genes from the citrus genome. A phylogenetic tree analysis revealed that the identified CsPMEs were divided into two groups/types. Some CsPMEs showed very close phylogenetic relationships with the PMEs whose functions were formerly addressed in Arabidopsis, tomato, and maize. Expression profiling showed that some CsPME genes are highly or specifically expressed in the leaf, root, flower, or fruit. Based on the phylogenetic relationships and gene expression profiling results, we suggest that some CsPMEs could play functional roles in pollen development, pollen tube growth, cross incompatibility, root development, embryo/seed development, stomata movement, and biotic/abiotic stress responses. Our results shed light on the biological roles of individual CsPME isoforms and contribute to the search for genetic variations in citrus genetic resources.