• Title/Summary/Keyword: Balance Development

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Available phosphorus levels modulate gene expression related to intestinal calcium and phosphorus absorption and bone parameters differently in gilts and barrows

  • Julia Christiane Votterl;Jutamat Klinsoda;Simone Koger;Isabel Hennig-Pauka;Doris Verhovsek;Barbara U. Metzler-Zebeli
    • Animal Bioscience
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    • v.36 no.5
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    • pp.740-752
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    • 2023
  • Objective: Dietary phytase increases bioavailability of phytate-bound phosphorus (P) in pig nutrition affecting dietary calcium (Ca) to P ratio, intestinal uptake, and systemic utilization of both minerals, which may contribute to improper bone mineralization. We used phytase to assess long-term effects of two dietary available P (aP) levels using a one-phase feeding system on gene expression related to Ca and P homeostasis along the intestinal tract and in the kidney, short-chain fatty acids in stomach, cecum, and colon, serum, and bone parameters in growing gilts and barrows. Methods: Growing pigs (37.9±6.2 kg) had either free access to a diet without (Con; 75 gilts and 69 barrows) or with phytase (650 phytase units; n = 72/diet) for 56 days. Samples of blood, duodenal, jejunal, ileal, cecal, and colonic mucosa and digesta, kidney, and metacarpal bones were collected from 24 pigs (6 gilts and 6 barrows per diet). Results: Phytase decreased daily feed intake and average daily gain, whereas aP intake increased with phytase versus Con diet (p<0.05). Gilts had higher colonic expression of TRPV5, CDH1, CLDN4, ZO1, and OCLN and renal expression of TRPV5 and SLC34A3 compared to barrows (p<0.05). Phytase increased duodenal expression of TRPV5, TRPV6, CALB1, PMCA1b, CDH1, CLDN4, ZO1, and OCLN compared to Con diet (p<0.05). Furthermore, phytase increased expression of SCL34A2 in cecum and of FGF23 and CLDN4 in colon compared to Con diet (p<0.05). Alongside, phytase decreased gastric propionate, cecal valerate, and colonic caproate versus Con diet (p<0.05). Phytase reduced cortical wall thickness and index of metacarpal bones (p<0.05). Conclusion: Gene expression results suggested an intestinal adaptation to increased dietary aP amount by increasing duodenal trans- and paracellular Ca absorption to balance the systemically available Ca and P levels, whereas no adaption of relevant gene expression in kidney occurred. Greater average daily gain in barrows related to higher feed intake.

A Servicism Model of the New Politics and Administration System (서비스주의 정치행정시스템의 구조와 운용 연구)

  • Hyunsoo Kim
    • Journal of Service Research and Studies
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    • v.11 no.2
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    • pp.1-19
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    • 2021
  • This study was conducted to derive a model of a sustainable politics and administration system that will enhance human happiness. A new long-term sustainable development model has been established based on the experience of the politics and administration system over the past thousands of years. Currently, the democratic political system and the bureaucratic administrative system dominate, but they are facing many problems. In this study, we analyzed the politics and administration system experienced by human society, and derived a model of a politics and administration system that is ideal for the present and future societies and is sustainable in the long term. The necessary condition should be a model that can solve the problems of the current politics and administration system. It must be a model that is faithful to the characteristics and essence of modern society. And as a sufficient condition to ensure long-term sustainability, it must be based on the common principles of human society. After analyzing the problems of the current system and analyzing the conditions required for the new system, the axioms that are the basis of the politics and administration system were presented. Based on the axioms, the structure and operation model of a new politics and administration system were derived. The derived model was named as a servicism politics and administration system. It is a dynamic model in which two opposing opponents recognize each other's contradictions and balance them dialectically in the space-time dimension.

Development of a Grid-based Daily Watershed Runoff Model and the Evaluation of Its Applicability (분포형 유역 일유출 모형의 개발 및 적용성 검토)

  • Hong, Woo-Yong;Park, Geun-Ae;Jeong, In-Kyun;Kim, Seong-Joon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.5B
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    • pp.459-469
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    • 2010
  • This study is to develop a grid-based daily runoff model considering seasonal vegetation canopy condition. The model simulates the temporal and spatial variation of runoff components (surface, interflow, and baseflow), evapotranspiration (ET) and soil moisture contents of each grid element. The model is composed of three main modules of runoff, ET, and soil moisture. The total runoff was simulated by using soil water storage capacity of the day, and was allocated by introducing recession curves of each runoff component. The ET was calculated by Penman-Monteith method considering MODIS leaf area index (LAI). The daily soil moisture was routed by soil water balance equation. The model was evaluated for 930 $km^2$ Yongdam watershed. The model uses 1 km spatial data on landuse, soil, boundary, MODIS LAI. The daily weather data was built using IDW method (2000-2008). Model calibration was carried out to compare with the observed streamflow at the watershed outlet. The Nash-Sutcliffe model efficiency was 0.78~0.93. The watershed soil moisture was sensitive to precipitation and soil texture, consequently affected the streamflow, and the evapotranspiration responded to landuse type.

Development of Sequential Mixing Model for Analysis of Shear Flow Dispersion (전단류 분산 해석을 위한 순차혼합모형의 개발)

  • Seo, Il Won;Son, Eun Woo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.4B
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    • pp.335-344
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    • 2006
  • In this study, sequential mixing model (SMM) was proposed based on the Taylor's theory which can be summarized as the fact that longitudinal advection and transverse diffusion occur independently and then the balance between the longitudinal shear and transverse mixing maintains. The numerical simulation of the model were performed for cases of different mixing time and transverse velocity distribution, and the results were compared with the solutions of 1-D longitudinal dispersion model (1-D LDM) and 2-D advection-dispersion model (2-D ADM). As a result it was confirmed that SMM embodies the Taylor's theory well. By the comparison between SMM and 2-D ADM, the relationship between the mixing time and the transverse diffusion coefficient was evaluated, and thus SMM can integrate 2-D ADM model as well as 1-D LDM model and be an explanatory model which can represents the shear flow dispersion in a visible way. In this study, the predicting equation of the longitudinal dispersion coefficient was developed by fitting the simulation results of SMM to the solution of 1-D LDM. The verification of the proposed equation was performed by the application to the 38 sets of field data. The proposed equation can predict the longitudinal dispersion coefficient within reliable accuracy, especially for the river with small width-to-depth ratio.

GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells

  • Jeonghyeon Moon;Seung Hoon Lee;Seon-yeong Lee;Jaeyoon Ryu;Jooyeon Jhun;JeongWon Choi;Gyoung Nyun Kim;Sangho Roh;Sung-Hwan Park;Mi-La Cho
    • IMMUNE NETWORK
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    • v.20 no.5
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    • pp.40.1-40.15
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    • 2020
  • The protein encoded by the Gene Associated with Retinoid-Interferon-Induced Mortality-19 (GRIM-19) is located in the mitochondrial inner membrane and is homologous to the NADH dehydrogenase 1-alpha subcomplex subunit 13 of the electron transport chain. Multiple sclerosis (MS) is a demyelinating disease that damages the brain and spinal cord. Although both the cause and mechanism of MS progression remain unclear, it is accepted that an immune disorder is involved. We explored whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells; we used a mouse model of experimental autoimmune encephalomyelitis (EAE) to this end. Six-to-eight-week-old male C57BL/6, IFNγ-knockout (KO), and GRIM-19 transgenic mice were used; EAE was induced in all strains. A GRIM-19 overexpression vector (GRIM19 OVN) was electrophoretically injected intravenously. The levels of Th1 and Th17 cells were measured via flow cytometry, immunofluorescence, and immunohistochemical analysis. IL-17A and IFNγ expression levels were assessed via ELISA and quantitative PCR. IL-17A expression decreased and IFNγ expression increased in EAE mice that received injections of the GRIM-19 OVN. GRIM19 transgenic mice expressed more IFNγ than did wild-type mice; this inhibited EAE development. However, the effect of GRIM-19 overexpression on the EAE of IFNγ-KO mice did not differ from that of the empty vector. GRIM-19 expression was therapeutic for EAE mice, elevating the IFNγ level. GRIM-19 regulated the Th17/Treg cell balance.

The impact of sports rehabilitation education on career and employment will through psychological resistance (스포츠 재활 교육이 심리적 반발을 통해 진로 및 취업 의지에 미치는 영향)

  • Song Ki-Jae
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.2
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    • pp.187-199
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    • 2024
  • Due to the educational ecosystem in South Korea, there is a significant need to explore a new balance for students who pursue sports rehabilitation education based on their academic performance, in order to help them adapt to their majors, find career paths, and foster motivation for employment. There is a lack of related research in this crucial phase. The purpose of this study is to ascertain the impact of sports rehabilitation education on career aspirations and employment motivation through psychological reactions. The research methodology involved conducting an online survey from December 11th to December 28th, 2023, targeting university students undergoing sports rehabilitation education, with a final collection of 212 survey responses used for analysis. The research findings indicate: firstly, that the knowledge of sports rehabilitation educators has a positive influence on voluntary psychology. Secondly, the competence of sports rehabilitation educators has a positive impact on voluntary psychology. Thirdly, the attitude of sports rehabilitation educators negatively affects involuntary psychology. Fourthly, voluntary psychology positively influences career aspirations. Finally, voluntary psychology positively influences employment motivation, while conversely, involuntary psychology negatively affects employment motivation. These research results are expected to contribute to the development of sports rehabilitation education that influences career paths and employment motivation through psychological reactions.

Development of Simulation for Estimating Growth Changes of Locally Managed European Beech Forests in the Eifel Region of Germany (독일 아이펠의 지역적 관리에 따른 유럽너도밤나무 숲의 생장변화 추정을 위한 시뮬레이션 개발)

  • Jae-gyun Byun;Martina Ross-Nickoll;Richard Ottermanns
    • Journal of the Korea Society for Simulation
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    • v.33 no.1
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    • pp.1-17
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    • 2024
  • Forest management is known to beneficially influence stand structure and wood production, yet quantitative understanding as well as an illustrative depiction of the effects of different management approaches on tree growth and stand dynamics are still scarce. Long-term management of beech forests must balance public interests with ecological aspects. Efficient forest management requires the reliable prediction of tree growth change. We aimed to develop a novel hybrid simulation approach, which realistically simulates short- as well as long-term effects of different forest management regimes commonly applied, but not limited, to German low mountain ranges, including near-natural forest management based on single-tree selection harvesting. The model basically consists of three modules for (a) natural seedling regeneration, (b) mortality adjustment, and (c) tree growth simulation. In our approach, an existing validated growth model was used to calculate single year tree growth, and expanded on by including in a newly developed simulation process using calibrated modules based on practical experience in forest management and advice from the local forest. We included the following different beech forest-management scenarios that are representative for German low mountain ranges to our simulation tool: (1) plantation, (2) continuous cover forestry, and (3) reserved forest. The simulation results show a robust consistency with expert knowledge as well as a great comparability with mid-term monitoring data, indicating a strong model performance. We successfully developed a hybrid simulation that realistically reflects different management strategies and tree growth in low mountain range. This study represents a basis for a new model calibration method, which has translational potential for further studies to develop reliable tailor-made models adjusted to local situations in beech forest management.

Comparative Study of Fish Detection and Classification Performance Using the YOLOv8-Seg Model (YOLOv8-Seg 모델을 이용한 어류 탐지 및 분류 성능 비교연구)

  • Sang-Yeup Jin;Heung-Bae Choi;Myeong-Soo Han;Hyo-tae Lee;Young-Tae Son
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.30 no.2
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    • pp.147-156
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    • 2024
  • The sustainable management and enhancement of marine resources are becoming increasingly important issues worldwide. This study was conducted in response to these challenges, focusing on the development and performance comparison of fish detection and classification models as part of a deep learning-based technique for assessing the effectiveness of marine resource enhancement projects initiated by the Korea Fisheries Resources Agency. The aim was to select the optimal model by training various sizes of YOLOv8-Seg models on a fish image dataset and comparing each performance metric. The dataset used for model construction consisted of 36,749 images and label files of 12 different species of fish, with data diversity enhanced through the application of augmentation techniques during training. When training and validating five different YOLOv8-Seg models under identical conditions, the medium-sized YOLOv8m-Seg model showed high learning efficiency and excellent detection and classification performance, with the shortest training time of 13 h and 12 min, an of 0.933, and an inference speed of 9.6 ms. Considering the balance between each performance metric, this was deemed the most efficient model for meeting real-time processing requirements. The use of such real-time fish detection and classification models could enable effective surveys of marine resource enhancement projects, suggesting the need for ongoing performance improvements and further research.

Review of No Net Loss(NLL) of Wetland and Suggestion of Appropriate NLL in Korea (내륙습지 총량관리제도의 고찰 및 도입 방안 제안)

  • Yujin Kang;Junhyeong Lee;Taewoo Lee;Duckgil Kim;Jaeseung Seo;Soojun Kim;Hung Soo Kim
    • Journal of Wetlands Research
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    • v.26 no.3
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    • pp.227-235
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    • 2024
  • Inland wetlands provide important ecosystem services or functions, including biodiversity conservation, water purification, flood control, and carbon sequestration. However, many inland wetlands are being degraded by urbanization and industrialization, raising the need for conservation and restoration. This study proposes the adoption of No Net Loss(NLL) of Wetland for wetland conservation and restoration in Korea by the review of the literatures. To this end,, we analyzed the wetland conservation and management systems of the United States, Canada, Germany, Japan, and Australia, and identified institutional features and success factors of each country, and sought ways to adapt them to domestic conditions of Korea. The case of the United States highlights the importance of legal frameworks and public-private collaboration, Canada demonstrates systematic management approaches, Germany maintains a balance between development and conservation, Japan underscores the need for cooperative conservation efforts, and Australia emphasizes the efficiency of offset markets. The introduction and operation of these schemes are expected to contribute to climate change mitigation, biodiversity conservation, and water quality improvement, but ongoing research and policy efforts are needed to ensure that the schemes are well established.

A Study on the Floating Island for Water Quality Improvement of a Reservoir (저수지 수질개선을 위한 인공식물섬 조성에 관한 연구)

  • Lee, Kwang-Sik;Jang, Jeong-Ryeol;Kim, Young-Kyeong;Park, Byung-Heun
    • Korean Journal of Environmental Agriculture
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    • v.18 no.1
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    • pp.77-82
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    • 1999
  • Three floating islands have been constructed for water quality improvement for a polluted irrigation reservoir. Each floating island consists of 10 segments. Each segment hay an area of $16m^2$(4×4m) and is made of wood frames and floats(polystyrene foam). We planted three species of aquatic macrophytes(Typha angustifolia, Zizania latifolia, and Phragmites australis) in floating island on June, 1998. They grew very well without death. We would like to evaluate Phragmites australis is the most suitable aquatic macrophyte that could be planted in a floating island because it maintained the best balance of its root and shoot among them. During their grown period, net primary productivity of Typha angustifolia was $962gDM/m^2$, Zizania latifolia was $1,115gDM/m^2$, and Phragmites australis was $523gDM/m^2$. From these data, it would be estimated to 5.0Kg uptake of nitrogen by aquatic macrophytes and phosphorus 0.8Kg in 3 floating islands. The floating islands worked well as a habitat of fish and prawns. Many kinds of insect lived on the floating islands. The floating island has not only the function of water quality treatment but also several advantages: improvement of landscape and species diversity; low cost of maintenance; low technology; unnecessary of energy; less susceptible to variations in pollutant loading. It could be evaluated a good measure of water quality improvement for an irrigation reservoir. However, it should be intensively studied to develop more light, strong, durable and low-priced frames for efficient floating islands.

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