• Progress in Superconductivity and Cryogenics
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• v.15 no.3
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• pp.40-48
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• 2013

Cryoablation device is a surgical instrument to produce the cooling effect to destroy detrimental biological tissue by utilizing low temperature around 110 K. Usually, this device has the concentrated cooling region, so that it is suitable for concentrated and thick target. Accordingly, it is hard to apply this device for the target which is distributed and thin target. In this study, the design procedure of a closed-loop cryoablation device with multiple J-T expansion part is developed for the treatment of incompetent of great saphenous vein. The developed cyoablation device is designed with the analysis of 1-dimensional (1-D) bio-heat equation. The energy balance is considered to determine the minimum mass flow rate of refrigerant for consecutive flow boiling to develop the uniform cooling temperature. Azeotropic mixed refrigerant R410A and zeotropic mixed refrigerant (MR) of R22 ($CHClF_2$) and R23 ($CHF_3$) are utilized as operating fluids of the developed cryoablation device to form the sufficient temperature and to verify the quality of the inside of cryoablation probe. The experimental results of R410A and the zeotropic MR show the temperature non-uniformity over the range are $244.8K{\pm}2.7K$ and $239.8K{\pm}4.7K$ respectively. The experimental results demonstrate that the probe experiences the consecutive flow boiling over the target range of 200 mm.

• Journal of Korean Academy of Nursing
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• v.30 no.1
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• pp.72-83
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• 2000

This study purports to review traditional health concepts of Korea by age, and to compare them to health concepts defined in western societies. Furthermore the study offers these results as the basis of construction for Korean nursing theory. Literature for the review were traditional health books published in Korea. These books are Euibangyoochui, Hyangyakjibsungbang, Dongeuibogam, Eiyangpyun, Dongeuisoosebowon, & Hwangjaenaekyung. In addition, articles that studied traditional literature or Korean medical history were reviewed when no publication of a primary source was available. In ancient Korean society, health was viewed as a 'good relationship or harmony with a supernatural subject', 'harmony of earth, water, fire, and air', and a 'long life with no illness'. The treatment aspect of medicine was emphasized in the middle-aged society. The health concepts in the pre-modern society included such concepts as 'jeongkhibojeon', 'adjustment to the nature', 'harmony between yang and yin', 'strengthening of jeongkhishin', 'circulation of owoonyookchi', 'kyungjok mind-body state' and 'jeongshimjeonghang'. Major health concepts in western literature were 'adaptation', 'role performance', 'actualization of human potential', 'adaptation and actualization of potential', and 'comfort'. Traditional health concepts of Korea focus on principles. They deliver abstract meanings, which make their measures uneasy. They believe in holism and unity with nature and especially emphasize the mental aspect. On the other hand, health concepts of western societies focus on phenomena. Their meanings are somewhat concrete, which make their measurements relatively easy. They see a person adapts positively to the environment as an independent being from the environment. These concepts have biopsychosocial aspects with no partial emphasis in the mental aspects. These traditional concepts of health were classified into two main perspectives. One is the unity of heaven & man, and the other is the unity of mind and body. The former perspective is based on the main concept of Chi. The latter has the main concept of ruling of the mind. The two main concepts discussed above need further examination for development of a nursing theory for Korean society. The application of circulation of Chi needs balance and harmony, and the application of ruling of mind needs temperance.

• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.215-221
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• 2019

The development of blockchain-based art trading platforms has not been revitalized despite the recent recovery of the cryptocurrency market. In this paper, we found that blockchain-based art trading platform is not revitalized due to the large volatility of cryptocurrency price. As a solution, we propose a trading system using dual types of cryptocurrency that one is Stablecoin and the other is legacy cryptocurrency. Through cryptocurrency dualization, the proposed system can satisfy both user's requirements of stability of art price and value growth of the blockchain system. In addition, the proposed system is expected to be able to balance the use of dual cryptocurrencies and market capitalization ratios according to market principles. Finally, the proposed cryptocurrency dualization is expected to be used in other applications that require both the stability of the value of transactions and the growth of the value of the blockchain system.

• Journal of Korean Elementary Science Education
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• v.33 no.1
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• pp.82-94
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• 2014

The purpose of this study is to develop teaching program which utilizes emotional intelligence elements as a measure to stimulate the motive and scientific attitude of learners and examine the effect of its application. The target unit for this study is 'world of plants' in the fourth grade of elementary school, and the teaching program is composed of 3 stages including I(encounter with myself), S(encounter with science), and U(encounter with friends). The teaching program is organized in the way to reflect 5 emotional intelligence elements including self-awareness, self-regulation, self-motivation, sympathy, and personal relations properly according to each stage of teaching program. The result of applying this program into actual classrooms is as follows. First, it is proven that the teaching program actually helps improving the motive of learners to study science. The emotional intelligence takes a role of positive motive for thinking, and the learners monitor their emotion and behavior patterns by using a mirror notebook to reduce their anxiety about science. Second, it is proven that the teaching program changes the science related attitude of learners positively. The emotional intelligence elements help the learners to create friendly feeling toward science subject and have a friendly attitude toward science and a sense of expectancy to science class. Third, it is proven that the teaching program contributes to the improvement of learners' science study achievement. The emotional intelligence takes an important role in improving the learners' science study achievement through the role of adjusting and controlling the recognition capability. However, emphasizing the emotional intelligence excessively also has a risk to break the balance between emotion and recognition, so it is considered that the balanced approach should be applied.

• Culinary science and hospitality research
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• v.17 no.4
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• pp.204-218
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• 2011

This research suggests development of medicinal food in the future, establishes a marketing strategy for securing and maintaining customers of medicinal food restaurants and proposes efficient management directions for medicinal food in the food service industry. The higher the level of medicinal food that can satisfy consumer demand for health such as prevention of adult diseases, fat content, Organic food, etc, the more the purchasing motives of medicinal food including repurchase intention and recommendation are shown. The result of the hypothesis testing shows that the purchasing motives in the influencing factors such as prevention of adult diseases, fat content, organic food, food balance have significant influence on satisfaction in the mediating factors. Based on these analysis results, this study offers useful information about medicinal food and management of a restaurant specializing in medicinal food.

• Journal of the Ergonomics Society of Korea
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• v.34 no.5
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• pp.473-485
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• 2015

Objective: This study provides strategies of how to effectively convert an invention, created at universities or government-funded research institutes, into a strong patent with the clear understanding of its unique technological characteristics. Background: Regardless of the amount of research funds available in our country and the decent number of intellectual property rights created using the funds, there was a deficit of more than KRW 6 trillion in the technology trade balance related with intellectual property rights in the year of 2014. One of the reasons was that the vast number of patents that were being produced by universities or by government-funded research institutes were merely performance-based patents, namely, so called "patents for patents". Another reason is that developed technology from research and development could not be transformed into a strong patent right properly due to the lack of related knowledge. Method: After reviewing various references mentioned on the patent strategies, the definition of a strong patent and the strategies of producing a strong patent for an invention drawn out from research performance will be supplied. Results: To produce a strong patent right at universities or government funded research institutes, one should use strategies for strong specifications, strategies of product patents and method patents, strategies of patent portfolios, strategies of know-how, strategies of inventions defined by numerical limitation and strategies of parameter inventions for a more strategic approach. Conclusion: Strong patent rights will be produced with the use of effective patent strategies provided in this study. Application: It is estimated that the results of this study will aid the establishment of strong patents for inventions developed by research performance at universities or government-funded research institutions.

• Journal of the Ergonomics Society of Korea
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• v.34 no.5
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• pp.363-375
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• 2015

Objective: This study aims to recognize the risk of current traffic systems and to investigate a method to decrease risk by doing exercise using an elastic-band and cognitive rehabilitation. Background: The existing traffic system usually focuses on the ordinary citizens, which may not be appropriate to the elderly. It may affect the cognition and walking speed of the elderly. This study tries to examine whether cognition and muscle training is appropriate to improve their vulnerability. Therefore this study will provide human ergonomics - based basic data in relation to the elderly to identify the risk of current signal system and to mitigate the risk. Method: A total of 30 elderly participants were divided into two groups: experimental and control groups. Experimental group (n=15) was trained to strengthen their muscles and to promote cognition, whereas control group (n=15) was not. The training was conducted twice a week for three weeks. To strengthen muscles, a yellow colored elastic-band was used, and a computer program for cognitive rehabilitation was used to develop cognition. In the experimental group, there were significant differences between pre and post exercises However, the control group didn't show any significant difference. The increase in cognition and walking speed was found in the experimental group, whereas there were no differences in the control group. Statistically there was no significant difference between the two groups. Results: The results of this study show that the exercise program using the elastic-band gave a positive effect on gait training thanks to the development of muscle power and balance. Conclusion: This study did not show any statistical difference or significant differences between the two groups, since time was restricted, we believe. Application: The results of the walking speed will help to prevent traffic collision.

• BMB Reports
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• v.36 no.2
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• pp.207-213
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• 2003

Peroxisome proliferator-activated receptors (PPARs) are orphan nuclear hormone receptors that are known to control the expression of genes that are involved in lipid homeostasis and energy balance. PPARs activate gene transcription in response to a variety of compounds, including hypolipidemic drugs. Most of these compounds have high affinity to the ligand-binding domain (LBD) of PPARs and cause a conformational change within PPARs. As a result, the receptor is converted to an activated mode that promotes the recruitment fo co-activators such as the steroid receptor co-activator-1 (SRC-1). Based on the activation mechanism of PPARs (the ligand binding to $PPAR{\gamma}$ induces interactions of the receptor with transcriptional co-activators), we performed Western blot and ELISA. These showed that the indomethacin, a $PPAR{\gamma}$ ligand, increased the binding between $PPAR{\gamma}$ and SRC-1 in a ligand dose-dependent manner. These results suggested that the in vitro conformational change of $PPAR{\gamma}$ by ligands was also induced, and increased the levels of the ligand-dependent interaction with SRC-1. Collectively, we developed a novel and useful ELISA system for the mass screening of $PPAR{\gamma}$ ligands. This screening system (based on the interaction between $PPAR{\gamma}$ and SRC-1) may be a promising system in the development of drugs for metabolic disorders.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.4
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• pp.1389-1400
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• 2013

This study developed an operating rule curve (ORC) for multipurpose water supply (irrigation and environmental water) in heightened agricultural reservoir. Among the 20 reservoirs in improvement project of agricultural reservoir dam heightening, the 4 representative reservoirs (Ungyang, Gungchon, Yongam and Unam) were selected for the study according to the analysis of statistical characteristics. Available environmental water supply amounts during irrigation and non-irrigation periods, which is the range from release restricted water level to high water level were estimated by water balance analysis using reservoir operation model. Reliability, resiliency and vulnerability criteria for water system performance were used to assess the multiple water supply capacity. The ORC was presented as the percentile rank for the daily reservoir water level from the results of reservoir operation using the past couple of decades weather data. The water levels for each percentile were divided into 3 buffer sections representing drought (5~25%), normal (25~75%), and flood (75~95%) year to operate the heightened agricultural reservoir with ORC.

• Journal of Yeungnam Medical Science
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• v.1 no.1
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• pp.13-23
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• 1984

Acute renal failure refers to a rapid reduction in renal function that usually occurs in an individual with no known previous renal disease. Development of a complication of acue renal failure in critically ill surgical patients is not unusual, and it causes high morbidity and mortality. Acute renal failure can be divided as Pre-renal (functional), Renal (organic), and Post-renal (obstructive) azotemia according to their etiologies. Early recognition and proper correction of pre-renal conditions are utter most important to prevent an organic damage of kidney. These measures include correction of dehydration, treatment of sepsis, and institution of shock therapy. Prolonged exposure to ischemia or nephrotoxin may lead a kidney to permanent parenchymal damage. A differential diagnosis between functional and organic acute renal failure may not be simple in many clinical settings. Renal functional parameters, such as $FENa^+$ or renal failure index, are may be of help in these situations for the differential diagnosis. Provocative test utilyzing mannitol, loop diuretics and renovascular dilators after restoration of renal circulation will give further benefits for diagnosis or for prevention of functional failure from leading to organic renal failure. Converting enzyme blocker, dopamine, calcium channel blocker, and propranolol are also reported to have some degree of renal protection from bioenergetic renal insults. Once diagnosis of acute tubular necrosis has been made, all measures should be utilized to maintain the patient until renal tubular regeneration occurs. Careful regulation of fluid, electrolyte, and acid-base balance is primary goal. Hyperkalemia over 6.5 mEq/l is a medical emergency and it should be corrected immediately. Various dosing schedules for medicines excreting through kidney have been suggested but none was proved safe and accurate. Therefore blood level of specific medicines better be checked before each dose, especially digoxin and Aminoglycosides. Indication for application of ultrafiltration hemofilter or dialysis may be made by individual base.