• Maxillofacial Plastic and Reconstructive Surgery
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• v.31 no.4
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• pp.349-352
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• 2009

Cementoblastoma is a benign ectomesenchymal odontogenic neoplasm that forms a mass of cementum or cementum-like tissue continuous with the tooth root. Cementoblastoma represents 1% to 6.2% of all odontogenic tumors, and occurs more than 75% arise in the mandible, with most cases arising in the molar and premolar regions. About 75% arises before the age of 30. Radiographically, it appears as a radiopaque mass with a thin radiolucent rim attached to the roots of a tooth. The recurrence rate is 37% in the current study and cortical expansion and perforation of the cortex are common findings in lesions that subsequently recurred. It is apparent that recurrence rate depends largely on the completeness of removal than any other factor. Here we present a 20 year old, female case of an unusual multiple recurrent cementoblastoma around a previous lesion which had been surgically excised 2 years ago.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.108.2-108.2
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• 2014

과거 달 탐사 미션으로 달에는 global magnetic fields는 존재하지 않고 표면에 국부적으로 자기장이 존재함이 확인되었다. 그러나 이렇게 측정된 자기장 데이터는 일정 고도 (> 20 km) 이상에서 측정되었기 때문에, 지표에 비해 그 세기가 매우 약해 자기장의 형태와 분포를 연구하는데 한계가 있다. 보다 자세한 연구를 위해서는 표면에서부터 다양한 고도에 이르는 위치에서 측정된 자기장 데이터가 필요하며, 이는 달 표토의 자화나 Swirl 형성 메커니즘을 이해하는데 중요한 정보이다. 따라서 본 연구에서는 큐브위성을 이용하여 저궤도부터 지표까지의 자기장을 측정하는 방안을 소개한다. 큐브위성은 달 궤도 모선에서 사출되어 자기이상 지역 표면에 충돌하는 임무를 가진다. 자력계는 모선과 큐브위성에 각각 탑재되어 자기장을 측정하며, 모선으로 부터 사출된 큐브위성은 충돌 직전까지 자기장을 측정하고 모선에 습득한 데이터를 실시간으로 전송한다. 이렇게 측정된 자기장 데이터는 모선의 궤도부터 표면에 이르기까지 여러 고도에서 측정되었기 때문에 자기이상 지역의 자기장 구조를 파악하는데 중요한 자료로 활용할 수 있다. 이에 본 연구에서는 달의 자기이상 지역과 큐브위성 임무 설계에 대하여 기술하였다.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.99.1-99.1
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• 2014

달은 global magnetic fields가 존재하지 않으나, 달 표면에 국지적으로 자기장이 존재하며 이러한 현상의 원인은 계속 연구중이다. 달의 자기이상 현상이 나타나는 지역 중 광학적으로 밝고 어두운 패턴이 관측되는 지역을 Swirl이라한다. Mare Crisium ($17.18^{\circ}N$, $59.1^{\circ}E$)은 표면에 2개의 자기이상 지역과 광학적으로 밝은 지역들이 존재하지만, Swirl로 잘 알려진 Reiner Gamma와 같은 지역의 광학적 밝기와 패턴의 차이가 있다. 이를 위해 본 연구에서는 Lunar Prospector (LP) 위성의 magnetometer (MAG) 자료를 이용하여 자기장 분포에 관한 연구 및 Clementine 위성의 UV/VIS 영상자료를 이용하여 광학적 특성 연구를 진행하였다. LP의 MAG 자료는 Mare Cirisium지역의 22.3 km 고도에서 관측된 744개의 자료를 활용하였으며, Clementine의 영상자료는 750 nm, 950 nm의 반사도에 따른 Optical Maturity (OMAT)를 활용하였다. Mare Crisium의 북쪽지역은 자기이상 현상과 OMAT의 고유특성이 동시에 나타나며 이는 swirl과 유사하다. 특히, Mare Cirisum서쪽에 있는 Proclus crater 잔해 일부가 Mare Crisium의 북쪽지역까지 퍼져있어 이와 관련하여 자기장 존재여부에 따른 광학적 특성의 차이점을 조사하였다. 본 논문에서는 Mare Crisium 지역의 Swirl 진위여부를 추론하며, 본 논문에서 이용한 방법의 유용성에 대하여 검증하고자 한다.

• Journal of Microbiology and Biotechnology
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• v.17 no.9
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• pp.1554-1557
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• 2007

Artemisia princeps Pampanini (AP) was fermented with Bifidobacterium infantis K-525 and its antiasthmic effect investigated. AP and fennented AP (FAP) reduced the IgE level in the blood of ovalbumin-induced asthmic mice. Moreover, FAP reduced the IgE, proinflammatory cytokine IL-6, and IL-4 levels in the trachea, as well as in the lung of the experimental asthmic mice, whereas AP only reduced the IgE and IL-6 levels in the lungs. Nonetheless, AP and FAP both inhibited the mRNA expression of IL-6 and TNF-${\alpha}$ in IgE-induced RBL-2H3 cells. The in vivo antiasthmic effect of FAP was more potent than that of AP. Therefore, these findings suggest that the enhanced antiasthmic effect of AP after bifidus fermentation was possibly due to the regulation of the proinflammatory cytokine biosynthesis of IL-6 and TNF-${\alpha}$.

• Journal of Applied Biological Chemistry
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• v.50 no.4
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• pp.259-263
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• 2007

Trapa pseudoincisa Nakai, an aquatic plant, was extracted with 80% aqueous MeOH, and the concentrated extract was successively partitioned with EtOAc, n-BuOH, and $H_2O$. The EtOAc fraction gave three compounds, which were isolated through the repeated silica gel and ODS column chromatographies. Based on the spectroscopic data obtained from NMR, MS, and IR, the chemical structures of the compounds were determined as cycloeucalenol (1), ursolic acid (2), and 2${\beta}$,3${\alpha}$,23-trihydroxyurs-12-en-28-oic acid (3). These triterpenoids were isolated for the first time from Hydrocaryaceae plants including T. pseudoincisa NAKAI.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.35 no.3
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• pp.187-192
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• 2009

Out of all oral malignant tumor, malignant lymphoma occurs in only 3.5%. Especially, most of the primary malignant lymphomas, which occur in the head & neck region are high-grade diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue (MALT) marginal zone B-cell lymphoma is very rare. In the head & neck region, malignant lymphoma is reported to occur in the thyroid, salivary gland, trachea, larynx, orbital lobe and the Waldeyer's ring. Among the Waldeyer's ring, palatal tonsil is reported to be the most common region, but, only 1 case report was published in Korea. Until now, there were no case reports of MALT lymphoma that occurred in the tongue. The purpose of this case report is to report and discuss on a case of MALT lymphoma of the tongue.

• Natural Product Sciences
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• v.13 no.2
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• pp.114-117
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• 2007

To evaluate antiallergic effect of Brassica rapa Metzg (BR, Family Cruciferae), which is widely used as a food source, its anti-asthmic effect was investigated. BR reduced IgE level in the blood of ovalbumin (OVA)-induced asthmic mice. BR also inhibited IgE and ploinflammatory cytokine IL-6 productions in trachea of OVA-induced mice, but did not inhibit IL-4 production. BR did not inhibit mRNA expression of proinflammatory cytokines IL-6 and IL-4 in IgE-induced RBL-2H3 cells. BR and its isolated components 10-undecenoic acid 2-methoxy methyl ester and galactosyl diglyceride potently inhibited the NO production of RAW264.7cells induced by lipopolysaccharide. These findings suggest that the anti-asthmic effect of BR may be due to the inhibition of the biosynthesis of proinflarnmatory cytokine IL-6 in macrophage and BR can improve IgE-induced allergic disease asthma.

• Journal of Society of Preventive Korean Medicine
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• v.5 no.1
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• pp.1-9
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• 2001

Chongripaldangum(鍾離八段錦) is a traditional exercise which is known as qi-gong. It was first mentioned in Sooginsibseo(修眞十書) published in Won dynasty. But it is very difficult to know how to master Chongripaldangum(鍾離八段錦). So we studied the training methods by analizing several books such as $\ll$遵生八?$\gg$ and $\ll$內外功圖說輯要$\gg$ which have pictures of the training methods. It is known that to train Chongripaldangum(鍾離八段錦) is not only limited to the exercise of the body but also training of the mind is an important factor. It is very imprtant to know that the system of Hyung(形), Qi(氣), Sin(神) is needed for Chongripaldangum(鍾離八段錦)

• Journal of Microbiology and Biotechnology
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• v.29 no.1
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• pp.55-58
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• 2019

Development of stable rCHO cell lines is still time consuming and labor intensive, although it is a critical step in the commercial development of recombinant antibodies. The current work demonstrates, for the first time, that electroporation of CHO cells with DMSO can enhance stable expression of recombinant antibodies in rCHO cells. Electroporation with DMSO resulted in an average 3.7-fold and 2.8-fold increases in expression levels of aflibercept and pembrolizumab, respectively, in pools of stable rCHO cells. It also resulted in an average of 2.2-fold and 2.6-fold increases in the expression of aflibercept and pembrolizumab, respectively, in single-cell derived rCHO clones. Simple batch cultures of rCHO cell clones with the highest expression produced 1.0 g/l for aflibercept and 1.4 g/l for pembrolizumab without a time-consuming gene amplification process. Electroporation with DMSO also shortened the development of rCHO cell lines to 2-3 months, allowing rapid establishment of stable rCHO cell lines with a desirable expression level antibodies.

• Journal of Applied Biological Chemistry
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• v.63 no.4
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• pp.335-338
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• 2020

Artemisia iwayomogi (Compositae), a perennial mugwort, is native to Korea and widely distributed in Japan, Russia, and China. A. iwayomogi and A. capillaris are similar in morphology and pharmacological activity and have been used for the same medicinal purposes in Korea. While various ingredients such as coumarins and flavonoids and their activity studies have been reported for A. capillaris, few studies have been conducted on the pharmacologically active components of A. iwayomogi. In Korea, A. capillaris is not economical because only young leaves are used as a medicinal material. Because of this, A. iwayomogi is frequently used in Korea, indicating the need to study its pharmacologically active components. Therefore, a phytochemical study was initiated to isolate active compounds from the aerial parts of A. iwayomogi. Finally, four coumarins, umbelliferone (1), esculetin (2), grevillone (3), and scoparone (4) were isolated for the first time from the aerial parts of A. iwayomogi in this study.