• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.168-171
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• 2006

The Haenyeo of Jeju exists as a unique human resource only in Korea and Japan in the world. Especially, the anti-Japan opposition movement of the Haenyeo of Jeju, which had started to get the right to live on their own in 1931, had developed as the national liberation movement by struggling against a colonial of Japan and the official regulation association that was a plundering organization of Japan. Accordingly, there is making an effort to register Jeju's women divers as The National Treasure in UNESCO's Memory of the world. In this research, we are going to make stuff like a digital storytelling, characters, animation movies, games, and hompage to let our children understand and succeed the spirit and culture of the Haenyeo. We'll also use these contents for the education. We examine ways to recreate the culture resources related to the Haenyeo who gradually vanishes.

• Health Policy and Management
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• v.16 no.3
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• pp.52-69
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• 2006

Researchers indicates several issues as to performance evaluation methods for public health centers. Firstly, health centers are passively involved in the evaluation process, the performance indicators are activity-oriented, and mostly unrealistic. Balanced Scorecard is one of the methods for evaluating organizational performance, which is utilized at current in many industries including public sector. The purposes of this study is to apply balanced scorecard approach to a public health center and to develop performance indicators as well as their vision and strategies. For developing performance indicators, researchers selected K City Public Health Center and implemented brainstorming with members of health promotion team. Through team process they suggested goals, strategies and several indicators they considered proper to accomplish their shared vision. And then appropriateness of the indicators were evaluated by professional researchers in health promotion field for consensus building by email questionnaire. Based on survey and professional consensus meeting, 11 performance indicators were tailored in four perspectives as well as 6 strategies and 10 strategic goals, which are steps for accomplishing shared vision of health promotion team. For details, refer to the paper. Most members of health promotion team were satisfied with the indicators. However issues such as low level of recognition and familiarity with a new concept of BSC, and cultural resistance to strategic approach in public organizations should be addressed for future application and dissemination of BSC technique to public health organizations.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.778-781
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• 2009

본 연구는 정기적인 건강검진을 받는 수검자들이 검진결과에 대한 상담을 받는 것이 건강증진행위에 좋은 영향을 줄 수 있는가에 대한 목적을 가지고 있으며 연구결과를 요약하면 다음과 같다. 1. 검증결과 인구의 일반적 특성에 따른 건강검진 후 교육 및 상담에 대한 만족도 정도는 성별에서는 여성보다 남성의 만족도가 높았고, 직렬의 경우 기능직공무원이 만족도가 높았으며, 재직기간이 오래 될수록 만족도가 높았다. 2. 건강검진 시 상담서비스 만족도와 건강증진행위의 관계 분석결과 만족도 내용에서 '검진결과 설명시 교정해야할 건강 위험에 대한 지적, '검진결과에 따른 건강 상담', '검진 후 결과에 대해 제공하는 상담 및 보건 교육', '검진 후 결과에 관련된 자료나 진료 혹은 상담안내'에서 건강증진행위와 영향관계를 가지고 있는 것으로 나타났다. 3. '검진결과 설명 시 교정해야 할 건강 위험에 대한 지적'은 식사조절과 건강관리행위, '검진결과에 따른 건강 상담'은 건강관리행위, '검진 후 결과에 대해 제공하는 상담 및 보건 교육'은 신체활동과 심리적 안정, '검진 후 결과에 관련된 자료나 진료 혹은 상담안내'는 건강관리행위와 영향관계를 가지는 것으로 나타났다. 위의 연구결과에서 나타난 건강검진서비스 만족도가 낮은 항목의 불만족요인을 분석하여 건강교육 프로그램 계획 시 교육내용에 포함한다면 건강검진서비스 만족도가 상승할 것이며, 건강증진행위를 높일 수 있다고 생각한다.

• Journal of Sensor Science and Technology
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• v.17 no.3
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• pp.195-202
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• 2008

A biosensor based on the measurement of capacitance changes has been designed and fabricated for simple and realtime detection of bacteria. Compared to an impedance measurement technique, the capacitance measurement can make additional measurement circuits simpler, which improves a compatability for integration between the sensor and circuit. The fabricated sensor was characterized by detecting Escherichia coli(E. coli). The capacitance changes measured by the sensor were proportional to E. coli cell density, and the proposed sensor could detect $1{\times}10^6$ cfu/ml E. coli at least. The real-time detection was verified by measuring the capacitance every 20 minutes. After 7 hours of E. coli growth experiment, the capacitance of the sensor in the micro volume well with $4.5{\times}10^5$ cfu/ml of initial E. coli density increased by 20 pF, and that in another wells with $1.5{\times}10^6$ cfu/ml and $8.5{\times}10^7$ cfu/ml initial E. coli density increased by 56 pF and 71 pF, respectively. The proposed sensor has a possibility of the real-time detection for bacterial growth, and can detect E. coli cells with $1.8{\times}10^5$ cfu in nutrient broth in 5 hours.

• Korean Journal of Veterinary Service
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• v.30 no.1
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• pp.115-123
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• 2007

The therapeutic effect of honeybee venom collected using be venom collector on bovine mastitis was investigated. Mastitic cows from four farms were selected in the Yang-pyeong areas. Chronic mastitic cows were injected with the various concentrations of honey-bee venom per day. There was a significant difference in the reduction rates of somatic cell counts (SCC) according to treatment concentration and method of bee venom. The milk SCC were significantly decreased in all concentrations of bee venom 3 days after treatment. The reduction rates of SCC in treatment of 3, 6, 12 and 24mg honeybee venom were 20, 43, 63.3 and 65.8% respectively. Honeybee venom treatment consisted of two methods, a syringeful and a Bovivet Spenstift. The treatment with Bovivet Spenstift was more effective in the reduction rates of SCC compared with the syringeful. Thirty two out of 53 quarters were cured by Bovivet Spenstift with 12mg bee venom per day for 14 days. The venom cure rates of bovine mastitis by Escherichia coli, Stapylococcus aureus, Gram positive bacteria and Gram negative bacteria were 33.3, 75, 75 and 43.8% respectively. These results suggested that bee venom treatment (by Bovivet Spenstift with 12mg) might be effective for treatment of bovine mastitis.

• Korean Journal of Veterinary Service
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• v.33 no.3
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• pp.287-292
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• 2010

This study was conducted to investigate effects of bee venom (Apis mellifera L.) on the calving, reproductive efficiency of Hanwoo dams and the growth performance and disease occurrence of calves. Eighty seven experimental dams were allocated into two groups, bee venom treated (n=53, BV) and non-treated (n=34, control) of Hanwoo dams in Icheon, Kyonggi province. Calving period ($14.08{\pm}4.8$) and percentages of retained placenta (7.5%) in BV was shortened compared to control ($17.2{\pm}4.3$, 14.7%, respectively. P>0.05). Post-placenta periods was similar between two groups (P>0.05). Postpartum days ($36.5{\pm}4.3$) to first estrus and calving interval ($358{\pm}18$) were shortened compared to control ($40.2{\pm}5.2$, $375{\pm}23$, respectively) but have not significantly affected (P>0.05). Body weights ($43.5{\pm}3.0$) and average daily gains (0.62) of calves before 30 days old in BV were significantly higher than control ($40.3{\pm}5.3$, 0.52, respectively). The occurrence of respiratory disease and diarrhea in BV was relatively lower compared with Control. The present results indicate that bee venom may affect reproductive efficiency of dams and growth performance of calves.

• Korean Chemical Engineering Research
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• v.50 no.1
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• pp.182-185
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• 2012

N-doped $TiO_2$nanotubes have been newly prepared by two stage sol-gel and strong-alkali hydrothermal process using $TiCl_4$ and hydrazine/ammonia aqueous solution as raw materials. These nanotubes revealed a well developed anatase crystalline phase and perfect nanotube morphology with the diameter around 10nm and the wall thickness below 3 nm. Also, they showed a superior visible light activity and yellowish color due to the light absorption redshifted by ~35 nm and ~25 nm compared to undoped $TiO_2$ nanotubes and anatase nanoparticles, respectively.

• Korean Journal of Veterinary Service
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• v.33 no.2
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• pp.177-183
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• 2010

This study was conducted to investigate the antibiotic effects of bee venom (Apis mellifera) on the growth performance and blood characteristics in broiler chicken. 1-day-old broiler chicks were randomly divided into 3 groups with 3 replicates of 5,000 birds each. The treatments were control without antibiotic and bee venom, 0.5ppm or 1ppm bee venom. The final body weight and body weight gain were significantly higher in bee venom than control (P<0.05). The feed conversion ratio in all treated groups were significantly improved as compared to that of control (P<0.05). No significant differences among the groups were observed in the contents of total cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, albumin and globulin in blood serum. The white blood cell, red blood cell, heterophil, lymphocyte, and stress indicator (heterophil:lymphocyte rate) were not significantly different among the groups. The superoxide dismutase-like activities in the groups that were water containing bee venom were significantly increased compared to those in the control group (P<0.05). It has been suggested that bee venom promotes the growth of broilers without any negative effect when added in broiler water.

• Korean Journal of Veterinary Service
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• v.31 no.2
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• pp.229-237
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• 2008

This study was conducted to evaluate the effect of honeybee venom, purified using bee venom collector, and feeding of probiotics on the body weight gain, growth rate and hematological characteristics of pigs. A total of 120 pigs were examined and divided into 4 groups 1) Control (basal diet), 2) BV (basal diet + bee venom), 3) PB (basal diet + probiotics), 4) BVPB (basal diet + BV + PB). Average daily weight gain improved significantly in all test groups, especially BVPB (P < 0.05) compared to the controls. There was a significant difference in the feed conversion rate (P < 0.05) and efficiency (P < 0.05) between BVPB and control pigs. Weight gain and survivability was higher in the tests than the controls, but white blood cell count was not. Serum total protein, albumin and IgG concentration of BVPB were slightly higher than those of controls. These results suggest that treated honeybee venom and probiotics should be used together to effectively increase the productivity of pigs.

• Biomolecules & Therapeutics
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• v.20 no.3
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• pp.273-279
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• 2012

Hesperidin, a flavanone present in citrus fruits, has been studied as potential therapeutic agents that have anti-tumor activity and apoptotic effects in several cancers, but there is no report about the apoptotic effect of hesperidin in human malignant pleural mesothelioma through the specificity protein 1 (Sp1) protein. We investigated whether hesperidin inhibited cell growth and regulated Sp1 target proteins by suppressing the levels of Sp1 protein in MSTO-211H cells. The $IC_{50}$ value of hesperidin was determined to be 152.3 ${\mu}M$ in MSTO-211H cells for 48 h. Our results suggested that hesperidin (0-160 ${\mu}M$) decreased cell viability, and induced apoptotic cell death. Hesperidin increased Sub-$G_1$ population in MSTO-211H cells. Hesperidin significantly suppressed mRNA/protein level of Sp1 and modulated the expression level of the Sp1 regulatory protein such as p27, p21, cyclin D1, Mcl-1, and survivin in mesothelioma cells. Also, hesperidin induced apoptotic signaling including: cleavages of Bid, caspase-3, and PARP, upregulation of Bax, and down-regulation of Bcl-$_{xl}$ in mesothelioma cells. These results show that hesperidin suppressed mesothelioma cell growth through inhibition of Sp1. In this study, we demonstrated that Sp1 acts as a novel molecular target of hesperidin in human malignant pleural mesothelioma.