• The Journal of Korean Medicine
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• v.23 no.4
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• pp.64-72
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• 2002

Objective: Ramulus mori (RM) has been known to be effective for the treatment of obesity. To show the effectiveness of RM in a more scientific way, RM extract was prepared and evaluated in high fat diet rats by measuring the changes of body weight and lipid metabolism as described briefly below. Methods: 200 g of crushed RM was extracted withmethyl alcohol. The extract was evaporated under reduced pressure to give 33.4 g. For 10 weeks, control group rats were fed a high fat diet, while the test group rats were fed with the same diet plus RM extract. The normal group was fed with a normal diet. 150 mg of RM extract per 1 kg of body weight was added to the diet in the test group rats. Results: The control group rats on the high fat diet gained weight significantly, whereas the test group rats on the high fat diet plus RM extract gamed less weight. The significant increase of liver weight caused by the high fat diet was also inhibited by the RM extract treatment. Total lipid, triglyceride and total cholesterol levels of serum in the high fat diet rats were remarkably increased, whereastheir levels on the high fat diet plus RM extract were less increased. While serum HDL-cholesterol levels were remarkably decreased in the high fat diet, its level was less decreased in the high fat diet plus RM extract. Furthermore, we observed that the activities of hepatic acetyl-CoA carboxylase and fatty acid synthetase increased under the high fat diet, while their activities under the high fat diet plus RM extract were getting back nearly to the normal levels of the normal diet rats. Conclusions: These result show that the obesity caused by a high fat diet was effectively inhibited by an RM extract. Our results also showed that the abnormal lipid metabolism caused by a high fat diet was effectively cured by adding RM extract.

• Composites Research
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• v.24 no.2
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• pp.46-50
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• 2011

This paper describes the state of the art for the development of metallic armor materials which are mainly used as armor plates of the combat vehicles. Several important micro-structural features affecting ballistic properties of the metallic armor are discussed. Optimization of the strength and toughness balance of the metallic armor is necessary for the improvement of the ballistic performance resulting from maximizing the resistance to the penetration of the bullet and also to brittle failure of the plates. Understanding and control of the adiabatic shearing phenomenon developed remarkably during high strain rate deformation is needed to prevent brittle failure of the metallic armor materials.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1070-1077
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• 2011

This paper is studied on the influence of machining conditions on weldability obtained by ultrasonic machining. The weldability estimation of dissimilar Ni-Cu sheets with the optimization of one-wavelength horn is confirmed by the use of ultrasonic machining. The optimal welding condition with tensile test by setting the ultrasonic machining parameters is suggested and the weldability is estimated by SEM observation and EDX-ray analysis. Experimental studies are worked with the measure of tensile strength and the analysis of SEM photograph after the ultrasonic machining of workpiece. Machining parameters of machining time, pressure, and amplitude are also applied to this paper.

• Journal of Electrical Engineering and Technology
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• v.10 no.4
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• pp.1899-1909
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• 2015

Glaucoma is one of the most common causes of blindness which is caused by increase of fluid pressure in the eye which damages the optic nerve and eventually causing vision loss. An automated technique to diagnose glaucoma disease can reduce the physicians’ effort in screening of Glaucoma in a person through the fundal retinal images. In this paper, optimal hyper analytic wavelet transform for Glaucoma detection technique from fundal retinal images is proposed. The optimal coefficients for transformation process are found out using the hybrid GSO-Cuckoo search algorithm. This technique consists of pre-processing module, optimal transformation module, feature extraction module and classification module. The implementation is carried out with MATLAB and the evaluation metrics employed are accuracy, sensitivity and specificity. Comparative analysis is carried out by comparing the hybrid GSO with the conventional GSO. The results reported in our paper show that the proposed technique has performed well and has achieved good evaluation metric values. Two 10- fold cross validated test runs are performed, yielding an average fitness of 91.13% and 96.2% accuracy with CGD-BPN (Conjugate Gradient Descent- Back Propagation Network) and Support Vector Machines (SVM) respectively. The techniques also gives high sensitivity and specificity values. The attained high evaluation metric values show the efficiency of detecting Glaucoma by the proposed technique.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.4
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• pp.81-90
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• 2017

This paper presents a smart seat for correction of driver posture while driving. We introduce good postures with seat height, seat angle, head height, back of knees, distances of foot pedals, tilt of seat, etc. There have been some studies on correction of good posture while driving, effects of driving environment on driver's posture, sitting strategies based on seating pressure distribution, estimation of driver's standard postures, and others. However, there are a few studies on guide of good postures while driving for problem of driver's posture using machine leaning. Therefore, we suggest a smart seat for correction of driver's posture based on machine leaning, 1) developed the system to get postures by 10 piezoelectric effect element, 2) collect piezoelectric values from 37 drivers and 28 types of cars, 3) suggest 4 types of good postures while driving, 4) analyze test postures by kNN. As the results, we can guide good postures for bad or problems of postures while driving.

• CELLMED
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• v.5 no.4
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• pp.26.1-26.3
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• 2015

A new physiotherapy named Ciliary Muscle Training method and one successful case had been reported first for treatment of Posner-Schlossman Syndrome (PSS), also known as Glaucomatocyclitic Crisis. When a person observed a back and forth moving object, the ciliary muscle would involuntarily do sometimes tense and sometimes relaxant exercise which can relieve the tensive state of the ciliary muscle of patients suffering PSS disease. Through this period of continued treatment, this ciliary muscle training method can improve the health status of the ciliary muscle and finally achieve the purpose of curing PSS disease. In this successful case, the patient's feedback result was very good after receiving our suggested ciliary muscle training method as an attempt to treat PSS, ill right eye of this PSS patient showed normal appearance without any differences from the other normal eye, his vision test values of naked eye were both 4.9 under nearly 200 degrees of myopia. High intraocular pressure (IOP) was mitigated, measured IOP value was in the normal (≦ 21 mmHg) and comfortable state without PSS relapse until now. Therefore, ciliary muscle training method could be a potential clinical treatment approach to PSS disease.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.34 no.6
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• pp.35-41
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• 2006

In this paper, we focus on improving the performance of the piezoelectric diaphragms of valveless micropumps. A circular lightweight piezoelectric composite actuator (LIPCA) with a high level of displacement and output force has been developed for piezoelectrically actuated micropumps. We used numerical and experimental methods to analyze the characteristics of the actuator to select optimal design. With the developed circular LIPCA, we fabricated a valveless micropump by photo-lithography and PDMS molding techniques. The displacement of the diaphragm, the flow rate and the back pressure of the micropump were evaluated and discussed. With a semi-empirical method, the flow rate with respect to driving frequency was predicted and compared with experimental one. The test results confirm that the circular LIPCA is a promising candidate for micropump application and can be used as a substitute for a conventional piezoelectric actuator diaphragm.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.5
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• pp.374-379
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• 2002

A new active muffler system has been developed and its superior performance on both noise reduction and engine torque increase is demonstrated with experiment. Main characteristic of the proposed muffler system is the use of destructive interference by transmission path difference of divided exhaust pipes to reduce major exhaust noise components thereby overcoming problems of other active exhaust noise control methods. The exhaust pipe is divided into two sections and joined again downstream. One divided pipe has a sliding mechanism to vary its length, which is controlled to make half wavelength transmission path difference for the major engine rpm frequency. In this system one divided pipe is used to control major rpm frequency and its Harmonics and another pipe is used to control noise component double the frequency of rpm. An after-market tuning muffler, which has very simple internal structure and minimal back pressure, is also installed to remove remaining wideband noise. To make the system to be small enough to be practical, conventional muffler is also installed and used in low rpm range and active muffler is only employed in high rpm range. Noise reduction of the proposed system is comparable to conventional passive muffler. The engine dynamo test has proved the proposed system can recover almost all the torque lost by conventional muffler.

• Biomolecules & Therapeutics
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• v.9 no.4
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• pp.298-306
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• 2001

To develop a novel transdermal delivery system of loxoprofen (LP), a potent antiinflammatory and analgesic agent, the effects of vehicle composition and drug loading dose on the skin permeation property were investigated. And in vivo skin absorption property studied by analysing the $C_{max}$ and AUC was investigated after applying the developed plaster systems on rabbit back skin. Addition of isopropyl myristate (IPM) and IPM-diethylene glycol monoethyl ether (DGME) cosolvent in the plaster showed higher permeation rates than those from propylene glycol laurate-DGME cosolvent systems. As the concentration of LP in the plaster increased from 0.56 mg/$\textrm{cm}^2$ to 1.19 mg/$\textrm{cm}^2$, the drug release and skin permeation rates increased linearly. At loading dose of 1.19 mg/$\textrm{cm}^2$, the flux reached 35.6 $\mu$g/$\textrm{cm}^2$/hr. New LP plasters showed a good adhesive property onto skin, and showed no crystal formation. The AU $C_{0-24hr}$ and $C_{max}$ after dermal application of LP plaster (60 mg/70 $\textrm{cm}^2$) were found to be 6951$\pm$230 ng.hr/ml and 400$\pm$44 ng/ml, respectively. And the plasma concentration maintained above 300 ng/ml up to 24 hr period. In the carrageenan-induced rat paw edema test, LP plaster showed similar inhibition rate with marketed ketoprofen (Ketoto $p^{R}$) plaster.aster.r.

• Journal of Power System Engineering
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• v.22 no.1
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• pp.11-17
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• 2018

The steady-state, incompressible and three-dimensional numerical analysis was carried out to evaluate the internal flow fields characteristics of wind tunnel contractions made by Morel's curve equations. The turbulence model used in this study is a realizable ${\kappa}-{\varepsilon}$ well known to be excellent for predicting the performance of the flow separation and recirculation flow as well as the boundary layer with rotation and strong back pressure gradient. As a results, when the flow passes through the interior space of the analytical models, the flow resistance at the inlet of the plenum chamber is the largest at $Z_m=300$, 400 mm, but the smallest at $Z_m=700mm$. The maximum turbulence intensity in the test section is about 2.5% when calculated by the homogeneous flow, so it is improved by about 75% compared to the 10% turbulence intensity at the inlet of the plenum chamber due to the contraction.