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Review of the UBC Porcine Model of Traumatic Spinal Cord Injury

  • Kim, Kyoung-Tae;Streijger, Femke;Manouchehri, Neda;So, Kitty;Shortt, Katelyn;Okon, Elena B.;Tigchelaar, Seth;Cripton, Peter;Kwon, Brian K.
    • Journal of Korean Neurosurgical Society
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    • v.61 no.5
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    • pp.539-547
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    • 2018
  • Traumatic spinal cord injury (SCI) research has recently focused on the use of rat and mouse models for in vivo SCI experiments. Such small rodent SCI models are invaluable for the field, and much has been discovered about the biologic and physiologic aspects of SCI from these models. It has been difficult, however, to reproduce the efficacy of treatments found to produce neurologic benefits in rodent SCI models when these treatments are tested in human clinical trials. A large animal model may have advantages for translational research where anatomical, physiological, or genetic similarities to humans may be more relevant for pre-clinically evaluating novel therapies. Here, we review the work carried out at the University of British Columbia (UBC) on a large animal model of SCI that utilizes Yucatan miniature pigs. The UBC porcine model of SCI may be a useful intermediary in the pre-clinical testing of novel pharmacological treatments, cell-based therapies, and the "bedside back to bench" translation of human clinical observations, which require preclinical testing in an applicable animal model.

Nursing Interventions In Korea (한국의 간호사들이 행하는 간호중재)

  • Yom, Young-Hee
    • Journal of Korean Academy of Nursing Administration
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    • v.4 no.1
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    • pp.33-71
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    • 1998
  • 본 연구의 목적은 한국의 간호사들이 행하는 간호중재를 규명하는 것이다. 연구대상은 한국의 2 병원에서 일하는 수 간호사와 평 간호사를 포함한 443면의 간호사이며, 연구도구는 Iowa Intervention Project Team 이 개발한 336 문항의 5점 척도로 이루어진 "간호중재"설문지를 사용하였다. 5점 척도는 다음과 같다 : (a) 거의 행하지 않는다 : (b) 거의 한달에 한번 행한다 : (c) 거의 일주일에 한 번 행한다 : (d) 거의 하루에 한 번 행한다 : (e) 하루에 여러 번 행한다. 한국자료를 위해 설문지는 본 연구자에 의해 한글로 번역되었고, Back-translation을 이용하여 한글로 번역한 설문지는 다시 bilingual nurse에 의해 영어로 옮겨졌고, 마지막으로 영어로 옮겨진 설문지를 원래의 영문으로 된 설문지와 비교한 후에(Equivalence Test) 수정${\cdot}$보완하여 사용하였다. 한국 간호사들은 336 간호중재 모두를 행하고 있으며, 21개의 간호중재가 적어도 하루에 한 번 정도는 이루어지고 있었다. 간호사들은 "생리적 : 복합영역"에 속하는 간호중재를 가장 빈번하게 행하였고, 이 중에서 "비경구적 투약"은 일주일에 거의 11번 정도로 가장 많이 행하여졌다. 가장 적게 행하는 간호중재는 "동물이용요법"이었다. 간호사들은 교육을 많이 받을수록, 임상경험이 많을수록 더 많은 간호중재를 빈번하게 행했다. 특히, 석사학위를 받은 간호사는 "행위 영역"에 속한 간호중재를 더 많이 행했는 데, 예를 들면 "적극적 경청", "적응 증진", "의사결정지지"등이다. 또한 4년제 대학을 졸업한 간호사들은 "생리적 : 복합영역"에 속한 간호중재들을 전문대학을 졸업한 간호사보다 더 많이 행했는 데, 예를 들면, "뇌부종 관리", "반사 장애 관리", "기구를 사용한 호흡"등이다. 10년 이상의 경험을 가진 간호사들은 "행위 영역"에 속한 간호중재를 임상 경험이 1년 미만이거나 또는 1-5년 사이의 경험을 가진 간호사보다 더 많이 행했는 데, 예를 들면, "죄책감 극복 증진", "진실 말하기"등이다. 또한 6-10년 사이의 임상경험을 가진 간호사들은 "자가 간호영역"에 속한 "옷 입히기", "두발 간호", "구강건강 유지" 등을 임상경험이 1년 미만인 간호사들보다 더 빈번하게 행했다. 이 연구는 간호중재 규명이 간호원가 산출을 위한 연구와, 간호의 질 향상을 위한 연구, 간호지식 탐구를 위한 연구에 공헌할 것을 기대한다.

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Analysis of Health Behaviors of Selected Health Professionals in South Korea (한국 보건전문가들의 보건행동에 관한 분석)

  • Kim, Sung-Hye;Larry K. Olsen
    • Korean Journal of Health Education and Promotion
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    • v.14 no.1
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    • pp.47-62
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    • 1997
  • 본 연구는 한국 보건전문가들의 보건행동을 조사하고, 보건행동간의 상호 관련 요인과 보건행동에 영향을 미치는 인구학적 요인을 분석하는데 그 목적이 있다. 본 연구 대상으로는 한국보건협회 산하의 8개의 보건 관련 학회 중에서 보건교육과 가장 관련이 있는 한국보건교육학회(212명)와 한국보건 간호학회 (124명) 회원 336명이 선정되었다. 본 연구의 도구는 미국에서 이미 실시된 여러 보건행동 연구를 기초로 하여 focus group discussion, back-translation, 전문가들의 panel discussion, 그리고 pilot test(사전조사)를 통하여 한국인의 보건행동 연구를 위해 타당하게 개발되었다. 본 연구를 위하여 1995년 약 두달동안(11월, 12월), 3차에 걸친 우편설문조사를 실시하여 64.3%의 응답회수율을 보였고, 응답자들의 보건행동을 분석하기 위해서 factor analysis(요인분석)와 ANOVA (변량분석) 방법을 사용하였다. 본 연구의 결과는 다음과 같다. 1. 조사응답자의 분포는 남자가 33.8%, 여자가 66.2%였고, 응답자의 80.3%가 석사 이상의 학위를 소유하고 있었다. 응답자들의 전공분야는 다양하였고, 그들 중에서 36.3%가 간호학, 24.4%가 공중보건학을 전공하였다. 응답자 중 과반수 이상이 학교에 근무하였고, 서울에 거주하였으며, 응답자의 평균 직장 근무연수는 14년 이였다. 2. 응답자들의 보건행동에 대한 요인분석 적용의 적합성을 사전검증하기 위하여 Bartlett’s Test of Sphericity (630.37, p〈.00)를 실시하였다. 응답자들의 보건행동을 요인분석한 결과, 17개의 보건행동으로 구성된 네가지 보건행동요인들이 추출되었다. 응답자들의 네가지 보건행동요인들은 다음과 같다: (1) 규칙적인 식사 및 과일 섭취 (2) 음주 및 흡연 (3) 외식,간식 및 카페인 음료 섭취 (4) 운동 및 휴식 3. 응답자들의 인구학적 요인과 네가지 보건행동요인들과의 관계를 분석한 결과, 성별(F=69.59, df=1,203, p〈.05), 교육정도(F=3.48, df=3,199, p〈.05) 그리고 직장(F=4.04, df=3,201, p〈.05)에 따라 음주 및 흡연 행동에 커다란 차이를 보였다. 또한 응답자의 직장 근무연수(F=2.39, df=5,185, p〈.05)에 따라 운동 및 휴식 행동에 커다란 차이를 보였다.

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Nursing Interventions Classification(NIC) Use in Korea : Oriental Medicine Hospitals and General Hospitals (간호중재분류(NIC)에 근거한 간호중재수행분석 II -한방병동과 일반병동 간호사를 중심으로-)

  • 염영희;김성실;김인숙;박원숙;김은주
    • Journal of Korean Academy of Nursing
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    • v.29 no.4
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    • pp.802-816
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    • 1999
  • The purposes of this research were to identify nursing interventions performed by Korean nurses and to compare the interventions performed by nurses working in the oriental medicine hospitals and with those performed by nurses working in the general hospitals. The samples consisted of 144 Korean nurses working in three hospitals, 70 nurses working in the oriental medicine hospitals and 74 nurses working in the general hospitals. The Nursing Interventions Classification (NIC) Use Questionnaire developed by the Iowa Intervention Project team was translated to Korean and verified using the method of back-translation. The questionnaire consists of 433 intervention labels and definition. Thirteen interventions were used at least daily by nurses working in the oriental medicine hospitals, while twenty-one interventions were used at least daily by nurses working in the general hospitals. The most frequently used interventions by nurses working in the oriental medicine hospitals were Documentation, Shift Report Vital Signs Monitoring, Pressure Ulcer Prevention, Positioning, Fall Prevention, Exercise Promotion, Intravenous (IV) Therapy, Pressure Ulcer care, and Bed Rest Care in that crder. For nurses working in the general hospitals the most frequent intervention was Analgesic Administration, followed by the interventions of Medication Administration : Parenteral and Intravenous Therapy (IV) Therapy, Documentation, Intravenous(IV) Insertion, Shift Report, Fall Prevention, Vital Signs Monitoring, Medication Adnninistraction : and, Fluid Monitoring, and Medication Maragement in that order. The interventions performed least often by nurses working in the oriental medicine hospitals were Hemodialysis Therapy and Bleeding Reduction : Antepartum Uterus, while the interventions performed least often by nurses working in the general hospitals were Rape Trauma Treatment and Contact Lens Care. The nurses working in the oriental medicine hospitals performed the interventions in the Physiological : Complex domain significantly more often than the nurses working in the general hospitals, while the nurses working in the general hospitals performed the intervention in the Behavior domain significantly more often than the nurses working in the oriental medicine hospitals. This study suggests that further study will be needed to developed and validate more interventions sensitive to Korean culture.

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Influence of Ligament Deficits and Isthmic Defects on Instability in Lumbar Spine (인대 결손과 협부 결손이 요추 불안정성에 미치는 영향)

  • Choi, Dae-Kyung;Kim, Yoon-Hyuk;Kim, Kyung-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.35 no.10
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    • pp.1205-1210
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    • 2011
  • Spinal instability known to be related to low back pain. However, the quantitative definition of spinal instability has not been established because there is a lack of consensus regarding clinical and radiological studies. In addition, the major factors affecting such instability have not been elucidated, although disc degeneration, disc injury, ligament injury, and isthmic defects are considered to result in such problems. In this study, individual and combined influences on spinal instability with a three-dimensional finite element model of a one-level lumbar spinal motion segment were investigated, under the assumption that the rotation and translation in the sagittal plane under flexion and extension represented the instability indices. The results could be helpful in understanding the causes and mechanisms of spinal instability in the lumbar spine.

The Character Recognition System of Mobile Camera Based Image (모바일 이미지 기반의 문자인식 시스템)

  • Park, Young-Hyun;Lee, Hyung-Jin;Baek, Joong-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.5
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    • pp.1677-1684
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    • 2010
  • Recently, due to the development of mobile phone and supply of smart phone, many contents have been developed. Especially, since the small-sized cameras are equiped in mobile devices, people are interested in the image based contents development, and it also becomes important part in their practical use. Among them, the character recognition system can be widely used in the applications such as blind people guidance systems, automatic robot navigation systems, automatic video retrieval and indexing systems, automatic text translation systems. Therefore, this paper proposes a system that is able to extract text area from the natural images captured by smart phone camera. The individual characters are recognized and result is output in voice. Text areas are extracted using Adaboost algorithm and individual characters are recognized using error back propagated neural network.

Omnidirectional Camera Motion Estimation Using Projected Contours (사영 컨투어를 이용한 전방향 카메라의 움직임 추정 방법)

  • Hwang, Yong-Ho;Lee, Jae-Man;Hong, Hyun-Ki
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.44 no.5
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    • pp.35-44
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    • 2007
  • Since the omnidirectional camera system with a very large field of view could take many information about environment scene from few images, various researches for calibration and 3D reconstruction using omnidirectional image have been presented actively. Most of line segments of man-made objects we projected to the contours by using the omnidirectional camera model. Therefore, the corresponding contours among images sequences would be useful for computing the camera transformations including rotation and translation. This paper presents a novel two step minimization method to estimate the extrinsic parameters of the camera from the corresponding contours. In the first step, coarse camera parameters are estimated by minimizing an angular error function between epipolar planes and back-projected vectors from each corresponding point. Then we can compute the final parameters minimizing a distance error of the projected contours and the actual contours. Simulation results on the synthetic and real images demonstrated that our algorithm can achieve precise contour matching and camera motion estimation.

Development of Korean Version of Acute Concussion Evaluation using Cross-cultural Translation Methodology: Pilot Study (Acute Concussion Evaluation의 한국어 번역 및 문화적 개작: 예비 연구)

  • Kim, Bo-min;Jo, Hee-geun;Koo, Ji-eun;Park, Ji-won;Han, Hyeon-ju;Seo, Ji-hye;Im, Hyeok-bin;Kim, Eun-mi;Jeong, Jun-su;Yoon, Ja-yeong
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.4
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    • pp.73-79
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    • 2019
  • Objectives The purpose of this study is to provide Korean version of mild traumatic brain injury assessment tool. Methods The original version of acute concussion evaluation (ACE) was translated into Korean, and it was then back-translated into English without any prior knowledge of ACE. Finally, the pre-final version of Korean version of acute concussion evaluation (K-ACE) was derived. 49 Korean patients who had been diagnosed with mild traumatic brain injury participated in the study and completed K-ACE. Overall, 44 data were used to analyze findings. Validity of the study was assessed based on Concurrent validity. Reliability was also evaluated using Cronbach's ${\alpha}$ and the intraclass correlation coefficient. Results The Cronbach's ${\alpha}$ value for each item presented a proper level of internal consistency with results of 0.711 to 0.893 in two evaluations, respectively. The intraclass correlation coefficient of the retest reliability was marked as 0.892 (95% CI 0.840~0.933). Concurrent validity demonstrated positive correlations between K-ACE and Korean version of postconcussional syndrome questionnaire. Conclusions The K-ACE is concluded as a valid and reliable tool for measuring mild traumatic brain injury and post-concussion symptoms. Upon completion of the follow-up study, the K-ACE will be well-utilized by both clinicians and researchers.

First Report of Fusarium oxysporum Causing Damping-off on Paprika in Korea (Fusarium oxysporum에 의한 파프리카 잘록병)

  • Park, Mi-Jeong;Back, Chang-Gi;Seo, Yunhee;Park, Jong-Han
    • Research in Plant Disease
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    • v.25 no.2
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    • pp.94-97
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    • 2019
  • In February 2019, a damping-off disease occurred at the seedling stage of paprika in a commercial nursery located in Cheorwon, Korea. A species of Fusarium was isolated from the diseased plant and it was identified as Fusarium oxysporum based on morphological characteristics and nucleotide sequence data of translation elongation factor $1-{\alpha}$ and the largest subunit of RNA polymerase. The isolate obtained was revealed to be pathogenic to the host plant through pathogenicity tests, and the reisolation of the pathogen confirmed Koch's postulates. This is the first report of damping-off caused by Fusarium oxysporum on paprika in Korea.

A Study on the Definition and Reception of the Terminus Technicus Architektonike through Architecture and Geonchuk in the Architectural Theory ('건축(建築)'과 '아키텍처(Architecture)'에서 아르키텍토니케(Architektonike) 개념의 수용에 관한 연구)

  • Kim, Young-Cheol
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.9
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    • pp.87-96
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    • 2018
  • The purpose of this study is to get a more fundamental definition of the term Architecture and Geonchuk through analyzing the origin and reception of the terminus technicus Architektonike. In Latin world the greek term Architektonike was adopted and replaced the term Constructio by Vitruvius and has played a significant role in the history of architecture. In the late 19th Century however, the word Architecture was translated into Geonchuk(建築) and has been dominantly used in countries such as Korea, Japan, and China. But the difference of the denotation between them has not yet been fully evaluated. The term Geonchuk signifies much the same as the Tektonik and remains as such in the architectural discourse. In this context, this study goes back to refer to the philosophy of Metaphysics by Aristotle. In his book the term Architektonike was defined for the first time as terminus technicus, and the philosophies in later Ages of Leibniz or of Kant adopted it to signify the world view in accordance with the time. However, the original thought of the Architektonike disappeared in architectural practice and has been used in most cases as a substitute for Oikodomike which denotes house-building. The usage of this word in later time shows that it lost its foundation to be interpreted not only in terms of principium cognoscendi, but also in terms of principium reale. From this the literal usage of the term architecture and Geonchuk has seldom to do with its original meaning and denotation of Architektonike and also they lost the status of terminus technicus for the discourse of arche which encompasses the meaning of both principle and universal order.